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Treatment of Brain Aneurysm

Due to the difficulties associated with the organization of treatment in Turkey, Switzerland, South Korea and India, we are not currently processing requests to these regions.

If you are interested in treatment in Germany, please leave a request and our specialists will contact you as soon as possible.

 

Cost for treatment

Brain Aneurysm Diagnostics
 from  368
Partial resection and coil embolization of brain aneurysm
 from  9825
Treatment of brain aneurysm by surgical clipping
 from  8606

Sana Hospital Duisburg

9.8/10
location_onGermany, Duisburg

Department of Neurosurgery

The Sana Hospital Duisburg is a maximum care medical center with 678 beds and 17 specialized departments. With the very latest innovations and high quality patient care, the clinic works for the benefit of a person and their health. The hospital ranks among the leading clinics in the region. In 2013, the hospital
Brain Aneurysm Diagnostics
1583
Partial resection and coil embolization of brain aneurysm
25256
Treatment of brain aneurysm by surgical clipping
23013

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Department of Adult and Pediatric Neurosurgery

According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! The hospital is one of the largest and leading university medical complexes in Europe. The hospital in Germany provides modern diagnostics and treatment of patients, a
Brain Aneurysm Diagnostics
2024
Partial resection and coil embolization of brain aneurysm
38216
Treatment of brain aneurysm by surgical clipping
34052

University Hospital Freiburg

9.7/10
location_onGermany, Freibung

Department of Adult and Pediatric Neurosurgery

The University Hospital Freiburg is famous for its rich history and is one of the oldest and most prestigious medical facilities in Germany (one of the three best medical institutions in the country). The hospital was based on the Faculty of Medicine of the Albert Ludwig University of Freiburg, which celebrated its 550th anniver
Brain Aneurysm Diagnostics
1688
Partial resection and coil embolization of brain aneurysm
28624
Treatment of brain aneurysm by surgical clipping
25857

University Hospital Frankfurt am Main

10/10
location_onGermany, Frankfurt am Main

Department of Adult and Pediatric Neurosurgery

According to the reputable Focus magazine, the University Hospital Frankfurt am Main ranks among the top German medical facilities! The hospital was founded in 1914 and today is a well-known German medical facility, which combines rich traditions and scientific innovations. A medical team of more than 6,500 employees cares about
Brain Aneurysm Diagnostics
1575
Partial resection and coil embolization of brain aneurysm
25374
Treatment of brain aneurysm by surgical clipping
22624

University Hospital Würzburg

9.2/10
location_onGermany, Würzburg

Department of Adult and Pediatric Neurosurgery

According to the Focus magazine in 2019, the University Hospital Würzburg ranks among the top national German hospitals! The hospital is one of the oldest medical facilities in Germany. The centuries-old traditions of first-class treatment are combined with the very latest achievements of modern evidence-based medicine and
Brain Aneurysm Diagnostics
1585
Partial resection and coil embolization of brain aneurysm
25241
Treatment of brain aneurysm by surgical clipping
22657

University Hospital Bonn

9.2/10
location_onGermany, Bonn

Department of Neurosurgery

According to the authoritative Focus magazine, the University Hospital Bonn ranks among the top ten medical facilities in Germany! The hospital was opened on January 1, 2001, although in fact it inherits the medical facility, which operated at the Faculty of Medicine of the University of Bonn. The hospital in Germany combin
Brain Aneurysm Diagnostics
1670
Partial resection and coil embolization of brain aneurysm
28844
Treatment of brain aneurysm by surgical clipping
25488

University Hospital Carl Gustav Carus Dresden

9.1/10
location_onGermany, Dresden

Department of Adult and Pediatric Neurosurgery

According to the prestigious Focus magazine, the University Hospital Carl Gustav Carus Dresden is among the top three hospitals in Germany! The hospital is the embodiment of the standards of modern high-quality medicine. Since the hospital positions itself as a maximum care medical facility, it represents all medical fields. The
Brain Aneurysm Diagnostics
1836
Partial resection and coil embolization of brain aneurysm
33558
Treatment of brain aneurysm by surgical clipping
30044

University Hospital Erlangen

9.1/10
location_onGermany, Erlangen

Department of Adult and Pediatric Neurosurgery, Spinal Surgery

According to the Focus magazine, University Hospital Erlangen ranks among the best medical facilities in Germany! The hospital is one of the leading healthcare facilities in Bavaria and offers top-class medical care distinguished by the close intertwining of clinical activities with research and training of medical students. The
Brain Aneurysm Diagnostics
1619
Partial resection and coil embolization of brain aneurysm
27115
Treatment of brain aneurysm by surgical clipping
24210

University Hospital Hamburg-Eppendorf

9.2/10
location_onGermany, Hamburg

Department of Adult and Pediatric Neurosurgery

According to the Focus magazine, the University Hospital Hamburg-Eppendorf ranks among the top ten hospitals in Germany! Since its foundation in 1889, the hospital has taken a leading position in the European medical arena and still occupies it until today. A highly competent medical team of more than 11,000 employees takes care
Brain Aneurysm Diagnostics
1854
Partial resection and coil embolization of brain aneurysm
33627
Treatment of brain aneurysm by surgical clipping
29950

University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of Neurosurgery

The University Hospital Ulm started its activities 35 years ago and during this time it has become one of the most prestigious medical institutions in Europe. The hospital is famous for its numerous discoveries and the world-class achievements in medicine and pharmaceuticals. The medical facility has 29 specialized departments a
Brain Aneurysm Diagnostics
1618
Partial resection and coil embolization of brain aneurysm
27014
Treatment of brain aneurysm by surgical clipping
24162

University Hospital Heidelberg

9.8/10
location_onGermany, Heidelberg

Department of Adult and Pediatric Neurosurgery

According to the Focus magazine, the University Hospital Heidelberg ranks among the top five hospitals in Germany! The hospital is one of the most advanced and reputable medical institutions not only in Germany, but throughout Europe. There are more than 43 specialized departments and 13 medical institutes, which cover all field
Brain Aneurysm Diagnostics
0
Partial resection and coil embolization of brain aneurysm
0
Treatment of brain aneurysm by surgical clipping
0

University Hospital Essen

9.6/10
location_onGermany, Essen

Department of Adult and Pediatric Neurosurgery

According to the authoritative Focus magazine the University Hospital Essen ranks among the top German hospitals! With 27 specialized departments and 24 institutes, the hospital in Germany is a maximum care medical facility. The hospital has 1,300 beds for inpatient treatment. A highly qualified medical team of more than 6,000 e
Brain Aneurysm Diagnostics
1582
Partial resection and coil embolization of brain aneurysm
25146
Treatment of brain aneurysm by surgical clipping
22990

University Hospital Jena

8.9/10
location_onGermany, Jena

Department of Adult and Pediatric Neurosurgery

According to the prestigious Focus magazine, the University Hospital Jena regularly ranks among the top German medical facilities! The hospital has positioned itself as a multidisciplinary medical facility with a long history of more than 200 years. Since its foundation, the hospital has been constantly developing and modernizin
Brain Aneurysm Diagnostics
1702
Partial resection and coil embolization of brain aneurysm
28515
Treatment of brain aneurysm by surgical clipping
25767

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of Neurosurgery

According to the prestigious Focus magazine, the University Hospital Halle (Saale) ranks among the top German medical facilities! The history of the hospital has more than 300 years, and during this time it managed to earn an excellent reputation not only in Germany, but throughout the world. The hospital positions itself as a s
Brain Aneurysm Diagnostics
1560
Partial resection and coil embolization of brain aneurysm
25178
Treatment of brain aneurysm by surgical clipping
22687

University Hospital Marburg UKGM

8.6/10
location_onGermany, Marburg

Department of Adult and Pediatric Neurosurgery

The University Hospital Marburg UKGM offers patients modern diagnostics and comprehensive therapy at the international level. As a maximum care hospital, the medical facility specializes in all fields of modern medicine ranging from ophthalmology to traumatology and dentistry. The main areas of specialization of the hospital are
Brain Aneurysm Diagnostics
1526
Partial resection and coil embolization of brain aneurysm
23701
Treatment of brain aneurysm by surgical clipping
21360

University Hospital of Ludwig Maximilian University of Munich

10/10
location_onGermany, Munich

Department of Adult and Pediatric Neurosurgery

According to the Focus magazine, the University Hospital of Ludwig Maximilian University of Munich is regularly ranked among the best medical institutions in Germany! The hospital is the largest multidisciplinary medical facility, as well as a leading research and training center in Germany and Europe. The hospital is proud of i
Brain Aneurysm Diagnostics
1674
Partial resection and coil embolization of brain aneurysm
28437
Treatment of brain aneurysm by surgical clipping
25470
| from Booking Health GmbH
Brain aneurysm is an abnormal ballooning or expansion of a brain blood vessel.

The most efficient treatment is the surgical one, i.e. resection, coiling and clipping.

The cost of partial resection and coiling starts at €9,825, the cost of treatment with surgical clipping starts at €8,606. You can find other prices on the Booking Health website.

The best hospitals in Europe are:

HospitalCountry, city
Sana Hospital DuisburgGermany, Duisburg
Charite University Hospital BerlinGermany, Berlin
University Hospital FreiburgGermany, Freiburg
University Hospital Frankfurt-am-MainGermany, Frankfurt-am-Main
University Hospital ErlangenGermany, Erlangen

 

Brain aneurysms are local enlargements of blood vessels. They look like a bag-shaped bulge. The wall in this place is weakened, and therefore aneurysm ruptures with hemorrhage into the subarachnoid space of the brain often occur. The risk of this complication increases with a lesion larger than 7 mm. Doctors in Europe perform endovascular procedures and microsurgical interventions to cut off the blood flow through the aneurysm. Thanks to experienced doctors and high-quality equipment, the effectiveness of treatment abroad exceeds 90%, and the risk of severe complications is three times lower than the world average.

Content

  1. How common are aneurysms
  2. Symptoms of brain aneurysm
  3. Diagnostics of brain aneurysm
  4. Do brain aneurysms require treatment
  5. Endovascular treatment of aneurysm
  6. Surgical treatment of brain aneurysm
  7. Where is it better to undergo treatment for brain aneurysms
  8. Treatment in Europe at an affordable price

How common are aneurysms 

 

Previously, the prevalence of brain aneurysms was judged solely by the number of subarachnoid hemorrhages that occurred as a result of their rupture. No asymptomatic vascular bulging was found. The frequency of ruptures is 10-15 cases per 100,000 population per year.

Today we have information about the prevalence of asymptomatic brain aneurysms. The disease affects approximately 2.8% of people. They are more common in women than in men, and are found predominantly in the age group over 30. 15-30% of patients have more than one aneurysm.

Risk factors: 

  • Arterial hypertension.
  • Family history of brain aneurysms.
  • Concomitant brain diseases. 
  • Hormone replacement therapy in postmenopausal women. 

The frequency of familial brain aneurysms is 7-20%. 

Symptoms of brain aneurysm

 

The brain aneurysm that has not yet ruptured usually causes no symptoms. 

The ruptured brain aneurysm causes hemorrhage. Blood accumulates in the subarachnoid space. The rupture results in the impaired blood supply to the brain, and a section of brain tissue often dies off. This condition is considered a hemorrhagic stroke. It is severe, poses a high risk of death and disability. If the person survives, they need surgery to prevent repeated hemorrhage.

Brain aneurysms can rarely cause symptoms. The symptomatic course is typical only for giant formations. They compress the structures of the brain. The clinical course of such aneurysms is called pseudotumorous, since they imitate a tumor. The pathology may cause transient ischemic brain disorders: a person may have impaired limb mobility, difficulty speaking, swallowing disorders or other focal symptoms, depending on the artery in which the aneurysm is located.

With giant bulging of blood vessels, the risk of rupture is several times higher. This group of patients requires treatment first.

Diagnostics of brain aneurysm

 

In developed countries, the main diagnostic option is MRI. The sensitivity of the diagnostic examination on modern devices for the detection of formations from 5 mm reaches 98%. A more informative diagnostic test involves the use of a contrast agent.

Another accurate diagnostic study is a CT scan. Doctors often use 3D reconstruction of the brain aneurysm to assess the type of blood supply and plan treatment. Nonetheless, the CT scan has a drawback: radiation exposure. Therefore, the method is not usually used repeatedly to monitor asymptomatic patients.

X-ray angiography is rarely used in developed countries, but it is still widely used in developing countries. This diagnostic test is informative, but it is invasive: it requires the administration of the contrast agent into the blood by catheterization of the arterial bed. This is the main disadvantage of angiography as compared with CT scans and MRI. With the use of the last ones, the contrast agent can be injected into the venous blood through the median cubital vein.

To undergo angiography, the patient has to be hospitalized, as the procedure can sometimes give complications. In Europe, it is carried out mainly in the presence of contraindications to the use of contrast agents for CT scans and MRI, for example, in case of renal failure. Although the diagnostic test is invasive, it is more accurate than CT scans and MRI for detecting small aneurysms – up to 3 mm.

Do brain aneurysms require treatment 

 

Diagnostic methods are improving, becoming more accurate, and therefore asymptomatic aneurysms, which a person did not even suspect, are increasingly being diagnosed in people in the brain. Do these patients need treatment? On the one hand, there is a risk of rupture of even a small aneurysm, which can result in the extravasation of blood into the brain, death or disability of the patient. On the other hand, most aneurysms never rupture in their lifetime, and surgical treatment itself carries certain risks. Therefore, when deciding on the need for treatment, doctors weigh the potential risks and benefits of medical procedures and neurosurgical interventions.

There are two large studies that have assessed the risk of rupture of asymptomatic brain aneurysms. As a result, the key risk factors for ruptured aneurysm were identified, the presence of which makes doctors decide on the need for treatment.

According to the ISUIA study, risk factors for ruptured brain aneurysm are as follows: 

  • The size of the formation is more than 7 mm.
  • Localization in the vertebrobasilar basin or in the region of the posterior communicating artery.
  • A history of subarachnoid hemorrhage.

A Japanese UCAS study found that the risk of ruptured aneurysm is: 

  • 0.36% per year for brain aneurysms with the size of 3-4 mm;
  • 0.5% for formations with the size of 5-6 mm.
  • 1.69% with the size of 7-9 mm.
  • 4.37% in case of reaching the size from 10 to 24 mm.
  • 33.4% with giant brain aneurysms from 25 mm.

The increased risk of rupture is indicated not only by the characteristic localization of the formation, but also by the presence of diverticula (wall protrusions) in it.

The authors noted that the data cannot be applied to the European population, since the Asian race is at higher risk of ruptured brain aneurysm. However, the trends are the same for residents of all countries and continents: the larger the formation, the more likely complications will arise. Accordingly, the more likely it is that the doctor will decide whether to treat such an aneurysm.

The rupture most often occurs when the size of the aneurysm is more than 1 cm. Nonetheless, it is relatively rare. Therefore, in absolute numbers, the amount of ruptured aneurysms less than 1 cm in size is much higher. For example, according to W. Sang, who described 627 ruptures, only 12% of cases were in formation of more than 1 cm, and almost 72% of cases of rupture were in aneurysms less than 7 mm in size. Thus, only formations of 4 mm or less should be considered safe.

Another predictive factor is aneurysm growth. If it increases over the year by 0.75 mm or more, then the risk of rupture during the year is 5.4%. Without any growth tendency observed, the likelihood of this complication is minimal.

Endovascular treatment of aneurysm

 

The safest treatment option is to remove the aneurysm with access through the blood vessels (endovascular intervention). In this case, doctors do not have to open the patient's skull. Endovascular treatment is the technique of choice for patients with aneurysms of the vertebrobasilar basin and the paraclinoid segment of the internal carotid artery.

To eliminate aneurysms, doctors most often use coils. They are injected into the aneurysm, after which blood coagulation occurs in this place and blood clots form. They fill the aneurysm and close the entrance to it, thereby stopping the blood flow. The endovascular technique provides better results for narrow-necked aneurysms. If the patient has a wide-necked aneurysm, specialists apply a stent- or balloon-assisted method in order to avoid the coil loops falling out. The techniques used by doctors are as follows:

  • Temporary occlusion (closure of the lumen) of the vessel supplying the blood with a balloon catheter. 
  • Reconstruction of the lumen of the artery with a stent at the level of the neck. 

Large, multi-chambered, and diverticular aneurysms are most difficult to treat. In such situations, doctors strive to occlude the main chamber and close the neck as tightly as possible so that no more blood flows into the bulging. If the blood flow inside the aneurysm is stopped, the risk of rupture is reduced to zero. However, some patients have recanalization, which is the restoration of blood flow through the pathological section of the vessel. Therefore, endovascular treatment, although safer, is less reliable than surgery.

Another problem that doctors face is pathological tortuosity, loops and kinks of the arteries. They are detected in 5% of patients. In such situations, foreign experts use guiding catheters.

Thus, endovascular treatment is safer, but less reliable than surgery. On average, its efficiency is 55%. In other patients, either it is not possible to close the aneurysm, or the blood flow through it is restored after some time (recanalization). The best European hospitals use modern technologies in order to achieve a successful and reliable blood flow shutdown through the aneurysm even in the most difficult cases, so the efficiency of manipulations is higher – it reaches 70%. But still, the results are worse than when performing the surgical intervention. Therefore, endovascular treatment is the method of choice for patients over 60 years of age or with concomitant diseases for whom conventional surgery may be unsafe.

Surgical treatment of brain aneurysm

 

The classic treatment option is surgery. With this approach, mortality and the risk of complications are higher, but the effectiveness of the treatment exceeds 90%. The surgical intervention is preferred in patients under 60 years of age who do not have severe chronic diseases.

The essence of the surgical intervention is that a clip is applied to the brain aneurysm foundation. It separates the formation from the blood vessel, and the blood flow through it stops.

In all hospitals, surgical intervention is effective, but not everywhere it is equally safe. The incidence of complications in different medical facilities ranges from 5 to 30%. To minimize health risks, you can receive medical treatment abroad.

Foreign centers apply high-quality intraoperative control of the procedure. Doctors use neuroimaging techniques to assess the state of blood vessels and brain tissue, to avoid damage to functionally important areas. When working in a narrow and deep wound, endoscopic assistance is used. To imagine the clipping area, doctors insert a thin tube with a video camera and lighting. The technique is used for small aneurysms that are inaccessible for imaging with a surgical microscope.

After performing the manipulations, doctors check whether the result has been achieved, whether the movement of blood through the artery and its large branches is not disturbed. For this, the following methods can be used:

  • Opening the lumen of the aneurysm.
  • Careful assessment of the clipping area using a surgical microscope or an endoscope.
  • Intraoperative Doppler ultrasound (a sensor that measures blood flow velocity is used);
  • Intraoperative angiography (the administration of a contrast agent into the vessels with X-ray images).

The radical nature of the surgical intervention is judged by the absence of blood flow in the aneurysm and the presence of normal blood circulation in the supplying artery and its branches.

The final results can only be assessed after 6 months. Until the expiration of this time, the results are considered intermediate.

The results of the intervention depend on the hospital in which the surgery is performed. In some neurosurgical centers, mortality rates reach 2.6%, and the risk of disability is 12%. Nonetheless, if you are undergoing treatment abroad, in one of the best hospitals, then the risk of an unfavorable outcome is reduced by 3 times.

Where is it better to undergo treatment for brain aneurysms  

 

It is better to have brain surgery in hospitals in developed countries. In this case, you can expect that the aneurysm will be completely cut off from the bloodstream, and the recanalization (restoration of blood flow) will not occur in the future. Doctors in Europe achieve good treatment results with minimal risk of complications.

There are several reasons for you to undergo medical treatment abroad:

  • The effectiveness of endovascular treatment reaches 70%, with the world average of 55%.
  • The effectiveness of endovascular treatment for small narrow-necked brain aneurysms exceeds 90%.
  • It is possible to successfully cut off the blood flow even through large and giant wide-necked aneurysms, containing several chambers, and diverticula.
  • To control the cause of surgical interventions, surgeons use high-precision intraoperative diagnostics, the latest surgical microscopes, and video endoscopic assistance.
  • The mortality rate of patients after brain surgery is 3 times less, the risk of disability is 3 times less, and the likelihood of complications is 6 times less.
  • The risk of restoring blood flow through an aneurysm within 6 months of observation does not exceed 5%, and in narrow-necked formations up to 25 mm, it approaches zero.

Timely and high-quality treatment of the brain aneurysm will help get rid of symptoms and avoid subarachnoid hemorrhages.

Treatment in Europe at an affordable price 

 

To undergo medical treatment in one of the European hospitals, please use the services of the Booking Health company. On our website, you can find out the cost of treatment in Europe and compare prices in order to book a medical care program at a favorable price. Thanks to our service, medical treatment in Europe will be easier and faster for you, and the cost of treatment will be lower.

You are welcome to leave your request on the Booking Health website. Our specialist will contact you and provide a free consultation on treatment in Europe. Booking Health will take care of the organization of your trip abroad. We will provide the following benefits for you:

  • We will select a hospital for medical treatment in Europe, whose doctors specialize in the treatment of brain aneurysms and achieve the best results.
  • We will solve the problem of the language barrier, and we will also help to establish communication with your doctor.
  • We will reduce the waiting time for the medical care program. You will undergo treatment on the most suitable dates.
  • We will reduce the price. When booking through our service, the cost of treatment in a European hospital will be lower due to the lack of overpricing and additional coefficients for foreign patients.
  • We will help you solve any organizational issues: we will draw up documents, meet you abroad and take you to the hospital, book a hotel, provide interpreting services.
  • We will prepare a program and translate medical documents. You will not need to repeat the previously performed diagnostic procedures. 
  • We will help you keep in touch with the hospital after treatment in Europe.
  • We will arrange additional diagnostic examinations and treatment in European hospitals, if required.
  • We will buy medicines in another country and forward them to your native country.

The world's leading doctors will take care of your health. The specialists of the Booking Health company will help reduce the cost of treatment, organize your trip, and you can fully focus on restoring your health.

Authors: Dr. Nadezhda Ivanisova, Dr. Sergey Pashchenko




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