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University Hospital Muenster

9.8/10 from 78 Votes

The University Hospital Muenster is one of the most respected multi-field medical centers in Germany. It consists of more than 30 departments and numerous research institutes and centers. Every year over 58,000 inpatients are treated here and nearly 475,000 patients receive medical care on the outpatient basis.

Brain cavernoma diagnostics
1356
Treatment of brain cavernoma by embolization with platinum coils (coiling)
18638
Treatment of brain cavernoma by partial resection and coiling
21816
location_onCountry: Germany
location_searchingCity: Muenster
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University Hospital Cologne

9.8/10 from 82 Votes

The University Hospital Cologne is included in the Focus magazine rating of top German hospitals 2017 and offers patients first-class medical care meeting the latest medical advancements.

Brain cavernoma diagnostics
1250
location_onCountry: Germany
location_searchingCity: Cologne
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University Hospital Rechts der Isar of the Munich Technical University

10/10 from 70 Votes

The Rechts der Isar Hospital is the University Hospital of the Technical University of Munich. There is intensive cooperation between the research facilities of the TU and the hospital in numbers of areas.

Brain cavernoma diagnostics
1462
location_onCountry: Germany
location_searchingCity: Munich
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Academic Hospital Bogenhausen Munich

9.2/10 from 43 Votes

With more than 36,000 patients annually and 1,000 beds, the Academic Hospital Bogenhausen is one of the largest clinics in Munich.

Brain cavernoma diagnostics
1375
location_onCountry: Germany
location_searchingCity: Munich

University Hospital Frankfurt am Main

10/10 from 97 Votes

The University Hospital Frankfurt is part of the Johann Wolfgang Goethe University Frankfurt am Main. The hospital was founded in 1914 and today it is a famous German medical institution with rich traditions. The hospital treats about 49,000 inpatients and 220,000 outpatients every year.

Brain cavernoma diagnostics
1355
location_onCountry: Germany
location_searchingCity: Frankfurt am Main
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Charite University Hospital Berlin

9/10 from 95 Votes

Being the medical school for both Humboldt University and Free University of Berlin and having a long experience, the Charite Hospital has gained wide recognition. It is regarded as one of the most research-intensive medical facilities in Germany and the largest university medical center in Europe.

Brain cavernoma diagnostics
2054
location_onCountry: Germany
location_searchingCity: Berlin
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Academic Hospital Schwabing Munich

8.5/10 from 7 Votes

The Schwabing Clinic is a modern medical facility with a high level of service. The clinic has high-tech modern equipment, making it one of the best hospitals not only in Germany but also in Europe. There are comfortable single and double rooms with shower and toilet, TV, telephone and radio.

Brain cavernoma diagnostics
1322
location_onCountry: Germany
location_searchingCity: Munich

Vivantes Neukölln Hospital Berlin

10/10 from 23 Votes

The Vivantes Neukölln Hospital is the maximum care hospital and one of the largest healthcare facilities in Berlin.   There are more than 20 specialized departments and centers, including pediatric departments. In total, the hospital has 1,200 beds.

Brain cavernoma diagnostics
1486
Treatment of brain cavernoma by embolization with platinum coils (coiling)
21056
Treatment of brain cavernoma by embolization with platinum coils (coiling)
21482
Treatment of brain cavernoma by partial resection and coiling
24583
location_onCountry: Germany
location_searchingCity: Berlin

Vivantes Humboldt Hospital Berlin

9.7/10 from 23 Votes

An academic clinic of the university medical complex Charité, the Vivantes Humboldt Hospital is one of the largest specialized medical institutions in Berlin.

Treatment of brain cavernoma by embolization with platinum coils (coiling)
21049
Treatment of brain cavernoma by partial resection and coiling
24586
location_onCountry: Germany
location_searchingCity: Berlin

Academic Hospital Asklepios Barmbek Hamburg

9.5/10 from 23 Votes

As an Academic Hospital of the University of Hamburg, the Asklepios Barmbek Hospital offers a wide range of medical services in the field of conservative and surgical treatment. The hospital was opened in 2005 and today it is one of the best and modern medical centers in Europe.

Treatment of brain cavernoma by embolization with platinum coils (coiling)
18406
Treatment of brain cavernoma by partial resection and coiling
21900
location_onCountry: Germany
location_searchingCity: Hamburg

Alfried Krupp Hospital in Essen-Ruettenscheid

7.4/10 from 42 Votes

With 900 beds and approximately 2,050 employees in two branches, the Alfried Krupp Hospital is one of the larger hospital institutions in Essen.

Brain cavernoma diagnostics
1340
Treatment of brain cavernoma by embolization with platinum coils (coiling)
18485
Treatment of brain cavernoma by partial resection and coiling
21419
location_onCountry: Germany
location_searchingCity: Essen
certificate

Tel Aviv Sourasky Medical Center

9.9/10 from 23 Votes

The Tel Aviv Sourasky Medical Center (Ichilov) is the second largest and one of the most advanced healthcare and research institutions in Israel. Founded in 1961, it still enjoys popularity among the local population and draws thousands of international patients.

Brain cavernoma diagnostics
0.00
location_onCountry: Israel
location_searchingCity: Tel Aviv

Rambam Health Care Campus Haifa

9.8/10 from 23 Votes

Rambam Health Care Campus is the largest and the most advanced hospital in Northern Israel. Founded in 1938, the medical center has a long history and a rich experience in providing comprehensive medical services in all medical specialties.

Brain cavernoma diagnostics
0.00
location_onCountry: Israel
location_searchingCity: Haifa

St. Vincentius Clinic Karlsruhe

9.8/10 from 23 Votes

The St. Vincentius Clinic is the largest multidisciplinary medical institution and academiс hospital of the Albert Ludwig University of Freiburg. Treatment and diagnosis of patients is conducted by doctors with a scientific degree. They are introducing the latest progressive techniques.

Treatment of brain cavernoma by embolization with platinum coils (coiling)
17262
Treatment of brain cavernoma by partial resection and coiling
19854
location_onCountry: Germany
location_searchingCity: Karlsruhe

Vivantes Auguste-Viktoria Hospital Berlin

9.7/10 from 23 Votes

The Vivantes Auguste-Victoria Hospital, has special expertise and received international recognition in the field of Urology, especially in the treatment of prostate cancer and also Oncology, Neurology, Cardiology and other directions.

Treatment of brain cavernoma by embolization with platinum coils (coiling)
21357
Treatment of brain cavernoma by partial resection and coiling
24122
location_onCountry: Germany
location_searchingCity: Berlin

Vivantes Am Urban Hospital Berlin

9.7/10 from 23 Votes

The Vivantes Am Urban Hospital is an academic clinic at the Charité University Hospital. Many departments of the hospital are recognized for their outstanding medical and patient care services.

Treatment of brain cavernoma by embolization with platinum coils (coiling)
21463
Treatment of brain cavernoma by partial resection and coiling
24343
location_onCountry: Germany
location_searchingCity: Berlin

About the disease

Cavernoma of brain is a cerebral vascular neoplasm that forms as a benign tumor in the brain. Cavernoma is mostly caused by neurological disorders. Brain cavernoma is mainly localized in the innate area of ​​the brain, most of all - in the hemisphere. The incidence of the disease - 0.6 cases per 100 000. The size of formation can be very different - from few millimeters to several centimeters. Most common size is about 3 centimeters.

The most dangerous complication of cavernoma is bleeding in brain, which can even result in death. According to recent findings risk of the brain bleeding varies from 0.25% to 16.5% annually. Probability of hemorrhage is increased for the patients, whose tumor affected brain stem. For patients who have already experienced  hemorrhage the chances of recurrent internal bleeding estimate 33.9%.

Cavernoma of brainstem

Cavernoma located in the brainstem is the most dangerous vascular formation. It develops in a relatively small size and after that it damages brain tissues. It becomes very dangerous for patients to have any kind of injuries. Even minor bruises caused by bleeding can lead to severe and focal cerebral damage. Specific neurological symptoms of this localization are dysfunctions of cranial nerves, dizziness, impaired movements of eyeballs, peripheral facial nerve paresis and bulbar or pseudobulbar disorders. In addition to that patient may develop symptoms of hypertension in midbrain.

Spinal cavernoma

Cavernous malformations of spinal cord are much rarer, but its recurrent bleeding may lead to progressive sensory, motor or autonomic function disorders. Often there is a dysfunction of the pelvic organs. Lack of timely diagnosis and treatment can lead to irreversible changes and severe disability. A significant number of patients, particularly those with a long treatment history, experience the disorder of senses as they lose ability to smell and touch things.

Symptoms 

  • Seizures similar to epilepsy
  • Severe headaches
  • Nausea
  • Emotional instability

Diagnosis

Main method of diagnosis is magnetic resonance imaging. Cavernoma may be an accidental "discovery" during the instrumental study conducted for other indications. Common types of this brain dysfunction are cavernoma of brainstem and spinal cavernoma. Approximately 54-74% of patients fully recover after treatment.

Magnetic resonance imaging is best in detecting both spinal and brainstem cavernomas. Resonance imaging gives 100% picture of the brain with 95% specificity of its all sectors. Another common diagnostic method is MRI. However, the use of this method is limited as picture presents information only about surrounding tissues of the affected area.

Treatment

Surgical removal of cavernomas is in most cases effective and can be applied in case of multiple hemorrhages of the cavities located in the deeper areas of the brain. Surgery also relieves patient of all possible risks, connected with this disease. After surgery chances of epilepsy attacks decrease and patient gets protection against subsequent hemorrhage. Surgical intervention is determined by the location and condition of patient's neoplastic brain formation.

During the surgery doctor usually achieves complete resection of malformation. He also decreases significantly the number of epileptic-like seizures and restores neurological function. Sign of complete cavernoma excision is cessation of bleeding. Choice of surgical approach is based on a thorough study of topography and MRI. Removing and malformation is made from its closest tangential location to the brainstem

Platinum coils embolization (coiling) is often used for treatment of malformations in the brain. According to MayfieldClinic.com, which is a medical site, this method uses technology of inserting with catheter platinum wire into the brain to prevent bleeding.

Partial resection and coiling is also an effective treatment option, which is a microsurgical removal of cavernoma.

If cavernoma is difficult to access, main method of treatment is radiosurgery. Radiosurgical treatment of cavernoma  is aimed primarily at reducing the risk of recurrent bleeding and epilepsy attacks. Today, medical literature describes 450 cases of patients with cavernomas, who underwent such treatment option as "gamma knife" .After “gamma knife" treatment risk of hemorrhage is reduced by 80% after the first two years. Subsequently, annual risk reduces by 1,1-3,3%.




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