Infantile fibrosarcoma is a congenital malignant tumor, which develops in soft tissue and most commonly manifests itself in a child before the age of 1. Infantile fibrosarcoma is considered to be an aggressive tumor, as it spreads fast and can become large if not treated on time. Most commonly, tumor develops in arms and legs. Later, it can spread to the trunk, that`s why it's so crucial to find it early. In rare cases, infantile fibrosarcoma can develop in the chest or back. It is not common for infantile fibrosarcoma to develop in any organs, as it almost always appears in soft tissues. Although the exact cause of infantile fibrosarcoma has not been definitely identified, doctors believe that gene aberration is the leading cause. In children with infantile fibrosarcoma gene fusion of ETV6 and NTRK3 has been identified.
If infantile fibrosarcoma becomes large in size, a child can experience ulceration of the skin, followed by the bleeding of the place where tumor is located. According to DoveMed, approximately 36-80% of all cases of infantile fibrosarcoma has been diagnosed right after the birth of a child. This condition is slightly more common among males than females. Infantile fibrosarcoma can be very large in size, in some cases exceeding 25 cm in length.
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