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Treatment of Infantile fibrosarcoma in children

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Cost for treatment

Diagnosis of fibrosarcoma in children
 from  1068.1
Chimiotherapy for fibrosarcoma in children (1 course)
 from  3830.2
Radiation therapy for fibrosarcoma in children
 from  16050

Rambam Health Care Campus Haifa

9.8/10
location_onIsrael, Haifa

Department of Pediatric Hematology and Oncology

The Rambam Health Care Campus Haifa is the largest and the most progressive hospital in Northern Israel. The medical center was founded in 1938 and nowadays is proud of its long history, rich and successful experience in providing comprehensive medical services in all medical fields. The hospital serves more than 2 million local
Diagnosis of fibrosarcoma in children
2526.7
Chimiotherapy for fibrosarcoma in children (1 course)
8999.1
Surgery resection of infantile fibrosarcoma
14018.4

Tel Aviv Sourasky Medical Center

9.9/10
location_onIsrael, Tel Aviv

Department of Pediatric Hematology, Oncology and Bone Marrow Transplant

The Tel Aviv Sourasky Medical Center is the second largest and one of the most advanced healthcare and research facilities in Israel. It began its work in 1961, but it is still popular among the local population and attracts thousands of international patients. The multidisciplinary medical center covers an area of ​​150,000 m&s
Diagnosis of fibrosarcoma in children
2424.4
Chimiotherapy for fibrosarcoma in children (1 course)
9065.1
Surgery resection of infantile fibrosarcoma
14352.8

University Hospital HM Monteprincipe Madrid

9/10
location_onSpain, Madrid

Department of Pediatric Hematology and Oncology

The University Hospital HM Monteprincipe Madrid is rightfully recognized as one of the best and most advanced medical facilities in Madrid and throughout the whole country. The hospital was opened in 1998 and in a short time has become a worthy example of top-class medical services. The hospital is part of the HM Hospitales Grou
Diagnosis of fibrosarcoma in children
1306.8
Chimiotherapy for fibrosarcoma in children (1 course)
5245.9

University Hospital Frankfurt am Main

10/10
location_onGermany, Frankfurt am Main

Department of Pediatric and Adolescent Medicine

According to the reputable Focus magazine, the University Hospital Frankfurt am Main ranks among the top German medical facilities! The hospital was founded in 1914 and today is a well-known German medical facility, which combines rich traditions and scientific innovations. A medical team of more than 6,500 employees cares about
Diagnosis of fibrosarcoma in children
3452.6
Chimiotherapy for fibrosarcoma in children (1 course)
11869.5
Surgery resection of infantile fibrosarcoma
16826.2

University Hospital Heidelberg

9.8/10
location_onGermany, Heidelberg

Department of Pediatric Oncology, Hematology, Immunology and Pulmonology

According to the Focus magazine, the University Hospital Heidelberg ranks among the top five hospitals in Germany! The hospital is one of the most advanced and reputable medical institutions not only in Germany, but throughout Europe. There are more than 43 specialized departments and 13 medical institutes, which cover all field
Diagnosis of fibrosarcoma in children
0
Diagnosis of fibrosarcoma in children
0
Chimiotherapy for fibrosarcoma in children (1 course)
0

University Hospital RWTH Aachen

8.9/10
location_onGermany, Aachen

Department of Pediatric and Adolescent Medicine

According to the prestigious Focus magazine, the University Hospital RWTH Aachen ranks among the top German hospitals! As a maximum care university medical facility, the hospital guarantees patients first-class medical services combined with a respectful and human attitude. The hospital integrates all the modern options for the
Diagnosis of fibrosarcoma in children
3883.8
Chimiotherapy for fibrosarcoma in children (1 course)
13156.5
Surgery resection of infantile fibrosarcoma
19087.8

University Hospital Hamburg-Eppendorf

9.2/10
location_onGermany, Hamburg

Department of Pediatric Hematology and Oncology

According to the Focus magazine, the University Hospital Hamburg-Eppendorf ranks among the top ten hospitals in Germany! Since its foundation in 1889, the hospital has taken a leading position in the European medical arena and still occupies it until today. A highly competent medical team of more than 11,000 employees takes care
Diagnosis of fibrosarcoma in children
3386.6
Chimiotherapy for fibrosarcoma in children (1 course)
11021.4
Radiation therapy for fibrosarcoma in children
25360.4

University Hospital Würzburg

9.2/10
location_onGermany, Würzburg

Department of Pediatric and Adolescent Medicine

According to the Focus magazine in 2019, the University Hospital Würzburg ranks among the top national German hospitals! The hospital is one of the oldest medical facilities in Germany. The centuries-old traditions of first-class treatment are combined with the very latest achievements of modern evidence-based medicine and
Diagnosis of fibrosarcoma in children
3355.8
Chimiotherapy for fibrosarcoma in children (1 course)
10918
Radiation therapy for fibrosarcoma in children
25337.3

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Department of Pediatric Oncology and Hematology

According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! The hospital is one of the largest and leading university medical complexes in Europe. The hospital in Germany provides modern diagnostics and treatment of patients, a
Diagnosis of fibrosarcoma in children
3408.6
Chimiotherapy for fibrosarcoma in children (1 course)
10833.3
Surgery resection of infantile fibrosarcoma
25603.1

University Hospital Tuebingen

9.2/10
location_onGermany, Tuebingen

Department of General Pediatrics, Pediatric Hematology and Oncology

According to the prestigious medical publication Focus, the University Hospital Tuebingen ranks among the top five German hospitals! The hospital was founded in 1805, therefore it is proud of its long history, unique experience, and outstanding achievements in the field of medical care, as well as research and teaching activitie
Diagnosis of fibrosarcoma in children
3729.8
Chimiotherapy for fibrosarcoma in children (1 course)
12361.2
Surgery resection of infantile fibrosarcoma
18148.4

University Hospital Bonn

9.2/10
location_onGermany, Bonn

Department of Pediatric Hematology and Oncology

According to the authoritative Focus magazine, the University Hospital Bonn ranks among the top ten medical facilities in Germany! The hospital was opened on January 1, 2001, although in fact it inherits the medical facility, which operated at the Faculty of Medicine of the University of Bonn. The hospital in Germany combin
Diagnosis of fibrosarcoma in children
3922.3
Chimiotherapy for fibrosarcoma in children (1 course)
12945.3
Radiation therapy for fibrosarcoma in children
25328.5

University Hospital Duesseldorf

9.5/10
location_onGermany, Duesseldorf

Department of Pediatric Oncology, Hematology and Clinical Immunology

According to the authoritative Focus magazine, the University Hospital Duesseldorf ranks among the top Germany hospitals! The hospital is an excellent example of a combination of high-quality health care, research and teaching activities. With more than 50,000 inpatients and about 300,000 outpatients every year, the hospital is
Diagnosis of fibrosarcoma in children
3306.3
Chimiotherapy for fibrosarcoma in children (1 course)
11118.2
Radiation therapy for fibrosarcoma in children
24864.3

University Hospital Muenster

9.8/10
location_onGermany, Muenster

Department of Pediatric Hematology and Oncology

According to the Focus magazine, the University Hospital Muenster ranks among the top German hospitals! The hospital belongs to the most prestigious medical institutions in Germany. The hospital is distinguished by a high professionalism of its doctors, state-of-the-art technological equipment and the availability of the most ad
Diagnosis of fibrosarcoma in children
3387.7
Chimiotherapy for fibrosarcoma in children (1 course)
11254.6
Radiation therapy for fibrosarcoma in children
25073.3

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of General Pediatrics, Pediatric Hematology, Oncology and Neuropediatrics

According to the prestigious Focus magazine, the University Hospital Halle (Saale) ranks among the top German medical facilities! The history of the hospital has more than 300 years, and during this time it managed to earn an excellent reputation not only in Germany, but throughout the world. The hospital positions itself as a s
Diagnosis of fibrosarcoma in children
3387.7
Chimiotherapy for fibrosarcoma in children (1 course)
11130.3
Radiation therapy for fibrosarcoma in children
25117.3

University Hospital Jena

8.9/10
location_onGermany, Jena

Department of Pediatric and Adolescent Medicine

According to the prestigious Focus magazine, the University Hospital Jena regularly ranks among the top German medical facilities! The hospital has positioned itself as a multidisciplinary medical facility with a long history of more than 200 years. Since its foundation, the hospital has been constantly developing and modernizin
Diagnosis of fibrosarcoma in children
3256.8
Chimiotherapy for fibrosarcoma in children (1 course)
10897.1
Surgery resection of infantile fibrosarcoma
18885.4

University Hospital Marburg UKGM

8.6/10
location_onGermany, Marburg

Department of Pediatric and Adolescent Medicine

The University Hospital Marburg UKGM offers patients modern diagnostics and comprehensive therapy at the international level. As a maximum care hospital, the medical facility specializes in all fields of modern medicine ranging from ophthalmology to traumatology and dentistry. The main areas of specialization of the hospital are
Diagnosis of fibrosarcoma in children
3256.8
Chimiotherapy for fibrosarcoma in children (1 course)
10923.5
Surgery resection of infantile fibrosarcoma
15931.9

About the disease

Infantile fibrosarcoma is a congenital malignant tumor, which develops in soft tissue and most commonly manifests itself in a child before the age of 1. Infantile fibrosarcoma is considered to be an aggressive tumor, as it spreads fast and can become large if not treated on time. Most commonly, tumor develops in arms and legs. Later, it can spread to the trunk, that`s why it's so crucial to find it early. In rare cases, infantile fibrosarcoma can develop in the chest or back. It is not common for infantile fibrosarcoma to develop in any organs, as it almost always appears in soft tissues.  Although the exact cause of infantile fibrosarcoma has not been definitely identified, doctors believe that gene aberration is the leading cause. In children with  infantile fibrosarcoma  gene fusion of ETV6 and NTRK3 has been identified.

If  infantile fibrosarcoma becomes large in size, a child can experience ulceration of the skin, followed by the bleeding of the place where tumor is located. According to DoveMed, approximately 36-80% of all cases of infantile fibrosarcoma  has been diagnosed right after the birth of a child. This condition is slightly more common among males than females.  Infantile fibrosarcoma can be very large in size, in some cases exceeding 25 cm in length.

Symptoms

  • Tumor, most commonly in the area of extremities
  • Ulceration and bleeding at the site where tumor is located
  • Tumor grows very quickly
  • Weight loss
  • Mood swings
  • Pain in the area of tumor

Diagnosis

  • During a physical examination, the doctor will palpate the area where tumor is located. Most commonly, it can be felt deeply under the skin or be visible if tumor grew large. The doctor will also ask about a family history of a patient to determine if infantile fibrosarcoma could be inherited.
  • An MRI and CT scan of the tumor help to determine its exact location, size and also dynamics of growth.
  • A biopsy of the affected tissue is important for a conclusive diagnosis, as it helps the doctor to determine for sure if the tumor is benign or malignant.

Treatment

  • Surgery resection is used for excision of the tumor. In some cases, several resections need to be performed to completely resect the tumor. Overall, this surgery has good prognosis and most children who underwent a surgery recover even if this tumor has been large. The most important prerequisite for a definite good prognosis is for a tumor not to spread to the internal organs.
  • Radiation therapy and chemotherapy are used to shrink the tumor and prevent it from spreading faster. These two therapies are also very beneficial in case a tumor has spread to internal organs.



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