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Treatment of Ovarian Yolk sac Tumor in Germany | ️Best Hospitals, Doctors, Prices | Booking Health™

Ovarian Yolk sac Tumor. Treatment in Germany

Best Hospitals of Germany for Treatment of Ovarian Yolk sac Tumor | Booking Health helps you choose the right clinic and save money | ️Highly qualified specialists | ️Professional support on all stages of treatment | Send request 24/7!

Best hospitals and doctors for ovarian yolk sac tumor treatment in Germany

Leading hospitals

Cost for treatment

Diagnostics of ovarian yolk sac tumor
1807
Chemotherapy of ovarian yolk sac tumor (1 course)
6627.45
Surgery treatment of ovarian yolk sac tumor
6870.7
Cancer rehabilitation
0.00
University Hospital Rechts der Isar Munich
Germany, Munich
University Hospital Rechts der Isar Munich
Overall rating9.8 / 10
The University Hospital Rechts der Isar Munich was founded in 1834. It combines long traditions with the very latest advances in modern medicine. The medical facility includes 33 specialized departments and 20 interdisciplinary centers, where patients can receive top-class medical care in all medical fields. The hospital annuall
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University Hospital Tuebingen
Germany, Tuebingen
University Hospital Tuebingen
Overall rating9.2 / 10
According to the prestigious medical publication Focus, the University Hospital Tuebingen ranks among the top five German hospitals! The hospital was founded in 1805, therefore it is proud of its long history, unique experience, and outstanding achievements in the field of medical care, as well as research and teaching activitie
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University Hospital Ulm
Germany, Ulm
University Hospital Ulm
Overall rating8.7 / 10
The University Hospital Ulm is an advanced medical complex that provides patients with high-class medical care using the very latest scientific achievements. The medical facility has been performing successful clinical activities for more than 40 years and has long earned an excellent reputation throughout Europe. The hospital r
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University Hospital Carl Gustav Carus Dresden
Germany, Dresden
University Hospital Carl Gustav Carus Dresden
Overall rating9.1 / 10
According to the reputable Focus magazine, the University Hospital Carl Gustav Carus Dresden ranks among the top five German hospitals! The hospital is the benchmark for modern high-quality medicine. Positioning itself as a maximum care medical facility, the hospital represents all medical fields. There are 26 specialized depart
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University Hospital Heidelberg
Germany, Heidelberg
University Hospital Heidelberg
Overall rating9.8 / 10
According to Focus magazine, the University Hospital Heidelberg ranks among the top five hospitals in Germany! The hospital is one of the most advanced and reputable medical institutions not only in Germany, but throughout Europe. There are more than 43 specialized departments and 13 medical institutes, which cover all fields of
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University Hospital Frankfurt am Main
Germany, Frankfurt am Main
University Hospital Frankfurt am Main
Overall rating10 / 10
According to the reputable Focus magazine, the University Hospital Frankfurt am Main ranks among the top German medical facilities! The hospital was founded in 1914 and today is a well-known German medical facility, which combines rich traditions and scientific innovations. A medical team of more than 6,500 employees cares about
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Charite University Hospital Berlin
Germany, Berlin
Charite University Hospital Berlin
Overall rating9 / 10
According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! The hospital is one of the largest and leading university medical complexes in Europe. The hospital in Germany provides modern diagnostics and treatment of patients, a
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According to the Focus magazine, the University Hospital of Ludwig Maximilian University of Munich is regularly ranked among the best medical institutions in Germany! The hospital is the largest multidisciplinary medical facility, as well as a leading research and training center in Germany and Europe. The hospital is proud of i
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University Hospital Erlangen
Germany, Erlangen
University Hospital Erlangen
Overall rating9.1 / 10
According to the Focus magazine, University Hospital Erlangen ranks among the best medical facilities in Germany! The hospital is one of the leading healthcare facilities in Bavaria and offers top-class medical care distinguished by the close intertwining of clinical activities with research and training of medical students. The
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University Hospital Halle (Saale)
Germany, Halle
University Hospital Halle (Saale)
Overall rating9.6 / 10
According to the prestigious Focus magazine, the University Hospital Halle (Saale) ranks among the top German medical facilities! The history of the hospital has more than 300 years, and during this time it managed to earn an excellent reputation not only in Germany, but throughout the world. The hospital positions itself as a s
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University Hospital Hamburg-Eppendorf
Germany, Hamburg
University Hospital Hamburg-Eppendorf
Overall rating9.2 / 10
According to the Focus magazine, the University Hospital Hamburg-Eppendorf ranks among the top ten hospitals in Germany! Since its foundation in 1889, the hospital has taken a leading position in the European medical arena and still occupies it until today. A highly competent medical team of more than 11,000 employees takes care
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University Hospital Würzburg
Germany, Würzburg
University Hospital Würzburg
Overall rating9.2 / 10
According to the Focus magazine in 2019, the University Hospital Würzburg ranks among the top national German hospitals! The hospital is one of the oldest medical facilities in Germany. The centuries-old traditions of first-class treatment are combined with the very latest achievements of modern evidence-based medicine and
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University Hospital RWTH Aachen
Germany, Aachen
University Hospital RWTH Aachen
Overall rating8.9 / 10
According to the prestigious Focus magazine, the University Hospital RWTH Aachen ranks among the top German hospitals! As a maximum care university medical facility, the hospital guarantees patients first-class medical services combined with a respectful and human attitude. The hospital integrates all the modern options for the
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University Hospital Duesseldorf
Germany, Duesseldorf
University Hospital Duesseldorf
Overall rating9.5 / 10
According to the authoritative Focus magazine, the University Hospital Duesseldorf ranks among the top Germany hospitals! The hospital is an excellent example of a combination of high-quality health care, research and teaching activities. With more than 50,000 inpatients and about 300,000 outpatients every year, the hospital is
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University Hospital Muenster
Germany, Muenster
University Hospital Muenster
Overall rating9.8 / 10
According to the Focus magazine, the University Hospital Muenster ranks among the top German hospitals! The hospital belongs to the most prestigious medical institutions in Germany. The hospital is distinguished by a high professionalism of its doctors, state-of-the-art technological equipment and the availability of the most ad
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University Hospital Bonn
Germany, Bonn
University Hospital Bonn
Overall rating9.2 / 10
According to the authoritative Focus magazine, the University Hospital Bonn ranks among the top ten medical facilities in Germany! The hospital was opened on January 1, 2001, although in fact it inherits the medical facility, which operated at the Faculty of Medicine of the University of Bonn. The hospital in Germany combin
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| from Booking Health GmbH

Yolk sac tumors (also known as endodermal sinus tumors) are neoplasms developing from germ cells, ovarian germ cell tumors. These are most common in girls and young women. The younger a patient is at the time of diagnosis, the better the prognosis. The average age of women with this condition is 19 years old, and after 40 years, yolk sac tumors are extremely rare. Doctors in medical centers in Germany perform sparing operations on the ovaries and use polychemotherapy. This combination of treatment methods allows for a survival rate of up to 95% in early-stage cancer. 

Content

  1. Treatment principles
  2. Treatment of women of reproductive age
  3. Treatment during menopause
  4. Treatment of yolk sac tumors in Germany

The disease is usually treated with surgery and chemotherapy. Men can undergo an inguinal orchiectomy and a retroperitoneal lymphadenectomy. Women have a hysterectomy.

You can undergo your treatment in one of the following hospitals: University Hospital Rechts der Isar Munich, Leverkusen Clinic, or University Hospital Tuebingen.

You do not have to organize your trip yourself, as the Booking Health specialists will take care of these concerns. They will advise a clinic, a doctor, and a treatment method. Our employees will make an appointment for you on the preferred date, without a long wait period. They will help to get a visa and complete the paperwork necessary for your trip. You will visit a clinic with an interpreter, and for any questions you can contact your personal coordinator 24/7.

Treatment principles

 

Yolk sac tumors are rare, accounting for up to 20% of malignant ovarian germ cell tumors. If untreated, yolk sac tumors progress rapidly, metastasize, and eventually lead to death. But if the disease is detected in time, it can be completely cured.

The very first symptom of the condition is often a palpable tumor-like mass in the abdominal cavity, because due to the active blood supply, the tumors reach large sizes, up to 30 cm. The final diagnosis is established using CT or MRI scans, (alpha-fetoprotein, AFP) tumor marker blood tests, and based on the results of a histological examination of the material removed during the operation.

The main methods for this pathology are surgical treatment, which can be performed in different extents, and chemotherapy. A treatment regimen for yolk sac tumors depends on the stage of cancer, the age of a woman at the time of diagnosis of the disease and her reproductive plans, and the presence of concomitant pathologies.

In most children, the pathology is detected at stage 1, which allows for a more sparing treatment. Yolk sac tumors are often combined with malformations of the genital tract.

Treatment of women of reproductive age

 

The treatment begins with elective or emergency surgery. Elective surgical treatment is performed after laboratory (a blood count test, liver and kidney function assessment, a blood test for infections, and AFP level assessment) and instrumental (MRI and CT scans) examinations. If there are indications for an emergency surgical intervention, the extent of the preoperative diagnostics is reduced. These indications are as follows:

  1. torsion of the tumor pedicle with rapidly progressive necrosis; 
  2. ruptures of the tumor capsule with the threat of spread of malignant cells to the abdominal cavity and retroperitoneal space. 

Elective surgery can be performed endoscopically (through 3 small punctures in the anterior abdominal wall). Should emergency operations be required, surgeons choose a midline laparotomy, which allows for a better overview of the surgical field. The removal of the ovary affected by the tumor is supplemented by the removal of the uterus or the affected regional lymph nodes whenever required.

A surgical intervention is followed by up to 6 courses of polychemotherapy at an interval of 3 weeks. In the early stages of cancer, and if a woman wants to maintain her reproductive potential, doctors may delay chemotherapy by conducting more careful medical supervision over time.

Treatment during menopause

 

Ovarian yolk sac tumors in menopausal patients require more intensive therapy. Even women with the early stages of the disease require only combination treatment, such as a surgical tumor removal with a full course of chemotherapy.

The extent of surgery often includes the removal of both ovaries, uterus, and regional lymph nodes. The supply of eggs in the ovaries is depleted at the time of menopause, and their hormonal activity is also minimal. In such a situation, doctors opt to reduce the risk of cancer recurrence through extended removal of the organs of the reproductive system.

When conducting polychemotherapy, doctors use platinum-based drugs, etoposide, and bleomycin. Medicines are combined to achieve the maximum anticancer effect. Physicians additionally prescribe symptomatic treatment, which helps to endure long-term use of chemotherapy drugs.

Treatment of yolk sac tumors in Germany

 

The treatment of yolk sac tumor in Germany includes surgery (usually minimally invasive), chemotherapy with modern drugs and a careful follow-up.

Surgical interventions can be performed even in the presence of metastases. Doctors remove the uterus with its appendages and all tumor foci that are found in the abdominal cavity. And even if not all metastases are removed, the disease can still be cured. Most women respond well to chemotherapy. During the treatment, doctors monitor its effectiveness with the help of (AFP) tumor marker blood tests.

You can undergo your treatment and rehabilitation for yolk sac tumors in one of the German hospitals. You are welcome to visit the Booking Health website to select the most suitable medical center. Here you can find prices, compare the cost of treatment in different hospitals and make your treatment appointment at the best price. The specialists of the Booking Health company will help you to select the most suitable clinics in Germany and organize your trip.

 

Authors: 

The article was edited by medical experts, board-certified doctors Dr. Nadezhda Ivanisova and Dr. Farrukh Ahmed. For the treatment of the conditions referred to in the article, you must consult a doctor; the information in the article is not intended for self-medication!

 

Sources:

National Center for Biotechnology

European Society of Gynaecological Oncology - ESGO

Healthline