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Ovarian Yolk sac Tumor. Treatment in Germany

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If you are interested in treatment in Germany, please leave a request and our specialists will contact you as soon as possible.

 

Cost for treatment

Diagnostics of ovarian yolk sac tumor
842.45
Chemotherapy of ovarian yolk sac tumor (1 course)
3002.95
Surgery treatment of ovarian yolk sac tumor
3031.95

University Hospital Rechts der Isar Munich

9.8/10
location_onGermany, Munich

Department of Gynecology, Mammology and Obstetrics

The University Hospital Rechts der Isar Munich was founded in 1834. It combines long traditions with the very latest advances in modern medicine. The medical facility includes 33 specialized departments and 20 interdisciplinary centers, where patients can receive top-class medical care in all medical fields. The hospital annuall
Diagnostics of ovarian yolk sac tumor
2558.1
Chemotherapy of ovarian yolk sac tumor (1 course)
9883.05
Surgery treatment of ovarian yolk sac tumor
8713.5

University Hospital Tuebingen

9.2/10
location_onGermany, Tuebingen

Department of Adult and Pediatric Gynecology, Mammology, Obstetrics

According to the prestigious medical publication Focus, the University Hospital Tuebingen ranks among the top five German hospitals! The hospital was founded in 1805, therefore it is proud of its long history, unique experience, and outstanding achievements in the field of medical care, as well as research and teaching activitie
Diagnostics of ovarian yolk sac tumor
2265.2
Chemotherapy of ovarian yolk sac tumor (1 course)
9430.65
Surgery treatment of ovarian yolk sac tumor
8810.65

University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of Obstetrics, Adult and Pediatric Gynecology

The University Hospital Ulm started its activities 35 years ago and during this time it has become one of the most prestigious medical institutions in Europe. The hospital is famous for its numerous discoveries and the world-class achievements in medicine and pharmaceuticals. The medical facility has 29 specialized departments a
Diagnostics of ovarian yolk sac tumor
2430.5
Chemotherapy of ovarian yolk sac tumor (1 course)
9569.85
Surgery treatment of ovarian yolk sac tumor
8674.35

University Hospital Carl Gustav Carus Dresden

9.1/10
location_onGermany, Dresden

Department of Adult and Pediatric Gynecology, Mammology, Obstetrics and Reproductive Medicine

According to the reputable Focus magazine, the University Hospital Carl Gustav Carus Dresden ranks among the top five German hospitals! The hospital is the benchmark for modern high-quality medicine. Positioning itself as a maximum care medical facility, the hospital represents all medical fields. There are 26 specialized depart
Diagnostics of ovarian yolk sac tumor
3123.6
Chemotherapy of ovarian yolk sac tumor (1 course)
11267.8
Surgery treatment of ovarian yolk sac tumor
10578.2

University Hospital Heidelberg

9.8/10
location_onGermany, Heidelberg

Department of Obstetrics, Adult and Pediatric Gynecology

According to Focus magazine, the University Hospital Heidelberg ranks among the top five hospitals in Germany! The hospital is one of the most advanced and reputable medical institutions not only in Germany, but throughout Europe. There are more than 43 specialized departments and 13 medical institutes, which cover all fields of
Diagnostics of ovarian yolk sac tumor
0
Chemotherapy of ovarian yolk sac tumor (1 course)
0
Surgery treatment of ovarian yolk sac tumor
0

University Hospital Frankfurt am Main

10/10
location_onGermany, Frankfurt am Main

Department of Adult and Pediatric Gynecology, Obstetrics and Mammology

According to the reputable Focus magazine, the University Hospital Frankfurt am Main ranks among the top German medical facilities! The hospital was founded in 1914 and today is a well-known German medical facility, which combines rich traditions and scientific innovations. A medical team of more than 6,500 employees cares about
Diagnostics of ovarian yolk sac tumor
2503
Chemotherapy of ovarian yolk sac tumor (1 course)
9002.9
Surgery treatment of ovarian yolk sac tumor
8216.15

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Department of Adult and Pediatric Gynecology, Mammology

According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! The hospital is one of the largest and leading university medical complexes in Europe. The hospital in Germany provides modern diagnostics and treatment of patients, a
Diagnostics of ovarian yolk sac tumor
3638.35
Chemotherapy of ovarian yolk sac tumor (1 course)
8485.25
Surgery treatment of ovarian yolk sac tumor
12470.45

University Hospital of Ludwig Maximilian University of Munich

10/10
location_onGermany, Munich

Department of Obstetrics, Adult and Pediatric Gynecology

According to the Focus magazine, the University Hospital of Ludwig Maximilian University of Munich is regularly ranked among the best medical institutions in Germany! The hospital is the largest multidisciplinary medical facility, as well as a leading research and training center in Germany and Europe. The hospital is proud of i
Diagnostics of ovarian yolk sac tumor
2401.5
Chemotherapy of ovarian yolk sac tumor (1 course)
9912.05
Surgery treatment of ovarian yolk sac tumor
9553.05

University Hospital Erlangen

9.1/10
location_onGermany, Erlangen

Department of Adult and Pediatric Gynecology, Mammology, Obstetrics

According to the Focus magazine, University Hospital Erlangen ranks among the best medical facilities in Germany! The hospital is one of the leading healthcare facilities in Bavaria and offers top-class medical care distinguished by the close intertwining of clinical activities with research and training of medical students. The
Diagnostics of ovarian yolk sac tumor
2376.85
Chemotherapy of ovarian yolk sac tumor (1 course)
9501.7
Surgery treatment of ovarian yolk sac tumor
8625.05

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of Gynecology and Mammology

According to the prestigious Focus magazine, the University Hospital Halle (Saale) ranks among the top German medical facilities! The history of the hospital has more than 300 years, and during this time it managed to earn an excellent reputation not only in Germany, but throughout the world. The hospital positions itself as a s
Diagnostics of ovarian yolk sac tumor
2529.1
Chemotherapy of ovarian yolk sac tumor (1 course)
8586.75
Surgery treatment of ovarian yolk sac tumor
8185.7

University Hospital Hamburg-Eppendorf

9.2/10
location_onGermany, Hamburg

Department of Gynecology and Mammology

According to the Focus magazine, the University Hospital Hamburg-Eppendorf ranks among the top ten hospitals in Germany! Since its foundation in 1889, the hospital has taken a leading position in the European medical arena and still occupies it until today. A highly competent medical team of more than 11,000 employees takes care
Diagnostics of ovarian yolk sac tumor
3087.35
Chemotherapy of ovarian yolk sac tumor (1 course)
8592.55
Surgery treatment of ovarian yolk sac tumor
10868.2

University Hospital Würzburg

9.2/10
location_onGermany, Würzburg

Department of Adult and Pediatric Gynecology, Mammology and Obstetrics

According to the Focus magazine in 2019, the University Hospital Würzburg ranks among the top national German hospitals! The hospital is one of the oldest medical facilities in Germany. The centuries-old traditions of first-class treatment are combined with the very latest achievements of modern evidence-based medicine and
Diagnostics of ovarian yolk sac tumor
2565.35
Chemotherapy of ovarian yolk sac tumor (1 course)
8611.4
Surgery treatment of ovarian yolk sac tumor
8307.5

University Hospital RWTH Aachen

8.9/10
location_onGermany, Aachen

Department of Gynecology, Mammology and Obstetrics

According to the prestigious Focus magazine, the University Hospital RWTH Aachen ranks among the top German hospitals! As a maximum care university medical facility, the hospital guarantees patients first-class medical services combined with a respectful and human attitude. The hospital integrates all the modern options for the
Diagnostics of ovarian yolk sac tumor
2923.5
Chemotherapy of ovarian yolk sac tumor (1 course)
9972.95
Surgery treatment of ovarian yolk sac tumor
9190.55

University Hospital Duesseldorf

9.5/10
location_onGermany, Duesseldorf

Department of Adult and Pediatric Gynecology, Obstetrics and Mammology

According to the authoritative Focus magazine, the University Hospital Duesseldorf ranks among the top Germany hospitals! The hospital is an excellent example of a combination of high-quality health care, research and teaching activities. With more than 50,000 inpatients and about 300,000 outpatients every year, the hospital is
Diagnostics of ovarian yolk sac tumor
2771.25
Chemotherapy of ovarian yolk sac tumor (1 course)
8578.05
Surgery treatment of ovarian yolk sac tumor
9089.05

University Hospital Muenster

9.8/10
location_onGermany, Muenster

Department of Adult and Pediatric Gynecology, Obstetrics

According to the Focus magazine, the University Hospital Muenster ranks among the top German hospitals! The hospital belongs to the most prestigious medical institutions in Germany. The hospital is distinguished by a high professionalism of its doctors, state-of-the-art technological equipment and the availability of the most ad
Diagnostics of ovarian yolk sac tumor
2603.05
Chemotherapy of ovarian yolk sac tumor (1 course)
8404.05
Surgery treatment of ovarian yolk sac tumor
8322

University Hospital Bonn

9.2/10
location_onGermany, Bonn

Department of Gynecology and Gynecologic Oncology

According to the authoritative Focus magazine, the University Hospital Bonn ranks among the top ten medical facilities in Germany! The hospital was opened on January 1, 2001, although in fact it inherits the medical facility, which operated at the Faculty of Medicine of the University of Bonn. The hospital in Germany combin
Diagnostics of ovarian yolk sac tumor
2746.6
Chemotherapy of ovarian yolk sac tumor (1 course)
9867.1
Surgery treatment of ovarian yolk sac tumor
9229.7
| from Booking Health GmbH

Yolk sac tumors (also known as endodermal sinus tumors) are neoplasms developing from germ cells, ovarian germ cell tumors. These are most common in girls and young women. The younger a patient is at the time of diagnosis, the better the prognosis. The average age of women with this condition is 19 years old, and after 40 years, yolk sac tumors are extremely rare. Doctors in medical centers in Germany perform sparing operations on the ovaries and use polychemotherapy. This combination of treatment methods allows for a survival rate of up to 95% in early-stage cancer. 

Content

  1. Treatment principles
  2. Treatment of women of reproductive age
  3. Treatment during menopause
  4. Treatment of yolk sac tumors in Germany

The disease is usually treated with surgery and chemotherapy. Men can undergo an inguinal orchiectomy and a retroperitoneal lymphadenectomy. Women have a hysterectomy.

You can undergo your treatment in one of the following hospitals: University Hospital Rechts der Isar Munich, Leverkusen Clinic, or University Hospital Tuebingen.

You do not have to organize your trip yourself, as the Booking Health specialists will take care of these concerns. They will advise a clinic, a doctor, and a treatment method. Our employees will make an appointment for you on the preferred date, without a long wait period. They will help to get a visa and complete the paperwork necessary for your trip. You will visit a clinic with an interpreter, and for any questions you can contact your personal coordinator 24/7.

Treatment principles

 

Yolk sac tumors are rare, accounting for up to 20% of malignant ovarian germ cell tumors. If untreated, yolk sac tumors progress rapidly, metastasize, and eventually lead to death. But if the disease is detected in time, it can be completely cured.

The very first symptom of the condition is often a palpable tumor-like mass in the abdominal cavity, because due to the active blood supply, the tumors reach large sizes, up to 30 cm. The final diagnosis is established using CT or MRI scans, (alpha-fetoprotein, AFP) tumor marker blood tests, and based on the results of a histological examination of the material removed during the operation.

The main methods for this pathology are surgical treatment, which can be performed in different extents, and chemotherapy. A treatment regimen for yolk sac tumors depends on the stage of cancer, the age of a woman at the time of diagnosis of the disease and her reproductive plans, and the presence of concomitant pathologies.

In most children, the pathology is detected at stage 1, which allows for a more sparing treatment. Yolk sac tumors are often combined with malformations of the genital tract.

Treatment of women of reproductive age

 

The treatment begins with elective or emergency surgery. Elective surgical treatment is performed after laboratory (a blood count test, liver and kidney function assessment, a blood test for infections, and AFP level assessment) and instrumental (MRI and CT scans) examinations. If there are indications for an emergency surgical intervention, the extent of the preoperative diagnostics is reduced. These indications are as follows:

  1. torsion of the tumor pedicle with rapidly progressive necrosis; 
  2. ruptures of the tumor capsule with the threat of spread of malignant cells to the abdominal cavity and retroperitoneal space. 

Elective surgery can be performed endoscopically (through 3 small punctures in the anterior abdominal wall). Should emergency operations be required, surgeons choose a midline laparotomy, which allows for a better overview of the surgical field. The removal of the ovary affected by the tumor is supplemented by the removal of the uterus or the affected regional lymph nodes whenever required.

A surgical intervention is followed by up to 6 courses of polychemotherapy at an interval of 3 weeks. In the early stages of cancer, and if a woman wants to maintain her reproductive potential, doctors may delay chemotherapy by conducting more careful medical supervision over time.

Treatment during menopause

 

Ovarian yolk sac tumors in menopausal patients require more intensive therapy. Even women with the early stages of the disease require only combination treatment, such as a surgical tumor removal with a full course of chemotherapy.

The extent of surgery often includes the removal of both ovaries, uterus, and regional lymph nodes. The supply of eggs in the ovaries is depleted at the time of menopause, and their hormonal activity is also minimal. In such a situation, doctors opt to reduce the risk of cancer recurrence through extended removal of the organs of the reproductive system.

When conducting polychemotherapy, doctors use platinum-based drugs, etoposide, and bleomycin. Medicines are combined to achieve the maximum anticancer effect. Physicians additionally prescribe symptomatic treatment, which helps to endure long-term use of chemotherapy drugs.

Treatment of yolk sac tumors in Germany

 

The treatment of yolk sac tumor in Germany includes surgery (usually minimally invasive), chemotherapy with modern drugs and a careful follow-up.

Surgical interventions can be performed even in the presence of metastases. Doctors remove the uterus with its appendages and all tumor foci that are found in the abdominal cavity. And even if not all metastases are removed, the disease can still be cured. Most women respond well to chemotherapy. During the treatment, doctors monitor its effectiveness with the help of (AFP) tumor marker blood tests.

You can undergo your treatment and rehabilitation for yolk sac tumors in one of the German hospitals. You are welcome to visit the Booking Health website to select the most suitable medical center. Here you can find prices, compare the cost of treatment in different hospitals and make your treatment appointment at the best price. The specialists of the Booking Health company will help you to select the most suitable clinics in Germany and organize your trip.

 

Authors: 

The article was edited by medical experts, board-certified doctors Dr. Nadezhda Ivanisova and Dr. Farrukh Ahmed. For the treatment of the conditions referred to in the article, you must consult a doctor; the information in the article is not intended for self-medication!

 

Sources:

National Center for Biotechnology

European Society of Gynaecological Oncology - ESGO

Healthline




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