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Clinic of Advanced Biological Medicine

The Clinic of Advanced Biological Medicine in Frankfurt am Main aims to boost the immune system, to maintain and improve the quality of life in case of disease, minimize side effects of toxic treatment, to increase chances for recovery as well as to increase life span through the use of effective treatments.
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Cancer: Ovarian yolk sac tumor — Chemotherapy. Treatment abroad

Ovarian yolk sac tumor is a rare and extremely malignant formation, characteristic mainly for girls 6 to 14 years old. The tumor develops from embryonic germ cells and produces alpha-fetoprotein, which serves as its marker. In approximately 5% cases, the disease is bilateral. The main treatment is surgery followed by chemotherapy.

Treatment Stages

The scope of manipulation depends on the tumor process prevalence and patient’s age. At stage I, the girls and young patients planning the childbirth undergo an organ-preserving intervention. The surgeon makes an abdominal incision through which s/he removes the ovary with the tumor and the adjacent fallopian tube. During surgery, the neighboring organs are scrutinized. The biopsy of the healthy ovary, peritoneum, diaphragm and any suspicious areas is performed. Tissue samples are sent for histological examination.

At a more advanced stage, the resection of the uterus with appendages and greater omentum is indicated. The surgery is performed by laparotomy, which allows a complete examination of the abdominal cavity. The swollen lymph nodes are removed, when required.

In patients with metastases, the cytoreductive intervention is performed to remove the maximum possible number of tumor nodules.

Surgical treatment is contraindicated if the patient is in serious somatic condition, for example, if she has diseases, such as:

  • diabetes,
  • kidney or liver failure,
  • severe cardiovascular disease.

A relative contraindication is the appearance of multiple metastases. In such cases, the treatment is initiated with chemotherapy, followed by surgery.

After surgery, all patients receive chemotherapy. Depending on the process stage, platinum drugs are recommended as a monotherapy or in combination with the other cytostatics. The number of courses varies from 3 to 6. The total treatment duration can be up to six months. At the 3rd stage of the disease, subject to a good treatment outcome, a repeated cytoreductive surgery is possible.

After treatment ,the patient should be followed up by the oncologist and undergo examinations, including the physical examination, determination of alpha-fetoprotein level and abdominal ultrasound. In the case of relapse, a second course of anti-tumor agents is recommend.

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University Hospital Bonn

9.2/10 from 150 Votes

Department of Oncology, Hematology, Rheumatology and Immunoncology

Chemotherapy of ovarian yolk sac tumor (1 course) #205701

The key objective of the Department of Internal Medicine III is to create and offer optimal treatments for internal diseases on inpatient, partially inpatient and outpatient basis.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Bonn
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Price 7427.00

University Hospital Cologne

9.8/10 from 82 Votes

Department of Internal Medicine I: oncology, hematology, clinical infectology, clinical immunology, hemostasis, intensive care

Chemotherapy of ovarian yolk sac tumor (1 course) #208517

The Department I for Internal Medicine of the University Hospital Cologne deals with the treatment of patients with various internal diseases. This includes in particular the following fields: Oncology, Hematology, Clinical infectology, Clinical immunology, Hemostasis, Intensive care.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Cologne
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Price 6438.00

University Hospital Frankfurt

9.5/10 from 97 Votes

Department of Hematology, Oncology, Rheumatology and Immunology

Chemotherapy of ovarian yolk sac tumor (1 course) #210899

The Department of Hematology, Oncology, Hemostasis, Rheumatology and Infectology at the University Hospital Frankfurt specializes in the treatment of all diseases of the hymatopoietic system and solid tumors.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Frankfurt am Main

Price 7218.00

Charite University Hospital Berlin

9/10 from 95 Votes

Charité Comprehensive Cancer Center

Chemotherapy of ovarian yolk sac tumor (1 course) #228935

The Charité Comprehensive Cancer Center integrates the clinical and research activities for all Charité departments and institutes dealing with Cancer. The director of the Charité Comprehensive Cancer Center is Prof. Dr. med. Ulrich Keilholz.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Berlin
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Price 8788.00

University Hospital Heidelberg

9/10 from 57 Votes

Department of Hematology, Oncology and Rheumatology

Chemotherapy of ovarian yolk sac tumor (1 course) #211405

The Department of Hematology, Oncology and Rheumatology at the Heidelberg University Hospital makes every effort to provide medical care of the highest quality to the patients with oncologic and rheumatologic diseases.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Heidelberg
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Städtisches Klinikum Schwabing

8.5/10 from 7 Votes

Department of Hematology, Oncology, Immunology, Palliative Medicine, Infectiology and Tropical Medicine

Chemotherapy of ovarian yolk sac tumor (1 course) #212869

The Department of Hematology, Oncology, Immunology, Palliative Medicine, Infectious Diseases and Tropical Medicine in Schwabing treats all benign blood diseases, disorders of the immune and coagulation system, all forms of blood cancer, and the most of cancers.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Munich

Price 5899.00

Hospital Nordwest

9.5/10 from 24 Votes

Department of Oncology and Hematology

Chemotherapy of ovarian yolk sac tumor (1 course) #220801

The Department of Oncology and Hematology at the Hospital Nordwest is a medical institution, which deals with the diagnosis, treatment and follow-up care of patients with benign and malignant tumors of the hematopoietic system, as well as all kinds of cancer.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Frankfurt am Main
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Price 5526.00

RWTH University Hospital Aachen

8.7/10 from 41 Votes

Department of Oncology, Hematology and Stem Cell Transplant

Chemotherapy of ovarian yolk sac tumor (1 course) #209765

The Department of Oncology, Hematology and Stem Cell Transplant provides patient care on both inpatient and outpatient basis. The focuses of the inpatient treatment are acute leukemia and high-dose chemotherapy followed by autologous blood stem cell transplantation.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Aachen
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Price 6225.00

Alfried Krupp Hospital in Essen-Ruettenscheid

7.4/10 from 42 Votes

Department of Internal Medicine I (Gastroenterology, Hematology, Onkology, Cardiology, Pulmology, Sport Medicine)

Chemotherapy of ovarian yolk sac tumor (1 course) #216833

The main treatment areas of the Department of Internal Medicine I, headed by Prof. Dr. med. Thomas Budde, are invasive and non-invasive cardiac diagnostics and therapy of all cardiac diseases.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Essen

Price 5254.00

University Hospital Dusseldorf

9.9/10 from 71 Votes

Department of Hematology, Oncology and Clinical Immunology

Chemotherapy of ovarian yolk sac tumor (1 course) #209089

The Department of Hematology, Oncology and Clinical Immunology at the University Hospital Dusseldorf provides treatment of patients with blood diseases, cancer and immune system diseases. The Department focuses on the treatment of malignant diseases of  blood, bone marrow and lymph nodes. .


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Duesseldorf

Price 7283.00

Hannover Medical School, MHH

9.8/10 from 43 Votes

Department of Hematology, Hemostaseology, Oncology and Stem Cell Transplantation

Chemotherapy of ovarian yolk sac tumor (1 course) #246793

The clinic of hematology, hemostasis, oncology and stem cell transplantation is a leading therapeutic clinic of the Medical Institute of Hannover for patients with solid tumor and systemic diseases, with other partially benign diseases of the hematopoietic system, as well as bleeding disorders.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Hannover
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Price 6315.00

Städtisches Klinikum Neuperlach

9.8/10 from 11 Votes

Department of Hematology and Oncology

Chemotherapy of ovarian yolk sac tumor (1 course) #196857

The department of hematology and oncology diagnosed and treated malignant tumors. The therapeutic spectrum includes all medicamentous treating methodes including chemotherapy, antibody, immune and hormone therapy. Cancer patients benefit from interdisciplinary treatment.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Munich

Price 5819.00

Waldbrol District Hospital of the Klinikum Oberberg

9.7/10 from 23 Votes

Department of Hematology, Oncology, Palliative Medicine and Sleep Laboratory

Chemotherapy of ovarian yolk sac tumor (1 course) #286406

The Department of Hematology, Oncology, Palliative Medicine, Pneumology and Somnology at the District Hospital of Waldbröl (Medical Department III) has 30 beds. A competent treatment is provided by three medical specialists in the field of hematology and oncology and a professional anesthesiologist.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Waldbrоl

Price 5303.00

University Hospital Halle (Saale)

9.6/10 from 78 Votes

Department of Hematology and Oncology (Department of Internal Medicine IV)

Chemotherapy of ovarian yolk sac tumor (1 course) #250833

The Department of Internal Medicine IV (Hematology and Oncology) covers the whole range of hematology and oncology. This includes prevention, diagnosis, therapy and post-operative care for cancer of all organs and blood.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Halle
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Price 6177.00

Gummersbach District Hospital of the Klinikum Oberberg

9.6/10 from 23 Votes

Department of Internal Medicine II (Hematology and Medical Oncology)

Chemotherapy of ovarian yolk sac tumor (1 course) #285721

The Department of Internal Medicine II at the Klinikum Oberberg in Gummersbach focuses on diagnosis and treatment of oncological and hematological diseases.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Gummersbach

Price 5219.00

Salem-Spital

9.6/10 from 29 Votes

Department of Oncology

Chemotherapy of ovarian yolk sac tumor (1 course) #196349

Specialists in Department of Oncology of Salem-Spital are also involved in Swiss Tumor Institute STI. Among our partners there is a competenct network that offers real advantages in diagnosis and therapy of tumors and treats patients as the focus of its work.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Switzerland
location_searchingCity: Bern