Cancer:
Ovarian yolk sac tumor — Chemotherapy. Treatment abroad

Ovarian yolk sac tumor is a rare and extremely malignant formation, characteristic mainly for girls 6 to 14 years old. The tumor develops from embryonic germ cells and produces alpha-fetoprotein, which serves as its marker. In approximately 5% cases, the disease is bilateral. The main treatment is surgery followed by chemotherapy.

Treatment Stages

The scope of manipulation depends on the tumor process prevalence and patient’s age. At stage I, the girls and young patients planning the childbirth undergo an organ-preserving intervention. The surgeon makes an abdominal incision through which s/he removes the ovary with the tumor and the adjacent fallopian tube. During surgery, the neighboring organs are scrutinized. The biopsy of the healthy ovary, peritoneum, diaphragm and any suspicious areas is performed. Tissue samples are sent for histological examination.

At a more advanced stage, the resection of the uterus with appendages and greater omentum is indicated. The surgery is performed by laparotomy, which allows a complete examination of the abdominal cavity. The swollen lymph nodes are removed, when required.

In patients with metastases, the cytoreductive intervention is performed to remove the maximum possible number of tumor nodules.

Surgical treatment is contraindicated if the patient is in serious somatic condition, for example, if she has diseases, such as:

  • diabetes,
  • kidney or liver failure,
  • severe cardiovascular disease.

A relative contraindication is the appearance of multiple metastases. In such cases, the treatment is initiated with chemotherapy, followed by surgery.

After surgery, all patients receive chemotherapy. Depending on the process stage, platinum drugs are recommended as a monotherapy or in combination with the other cytostatics. The number of courses varies from 3 to 6. The total treatment duration can be up to six months. At the 3rd stage of the disease, subject to a good treatment outcome, a repeated cytoreductive surgery is possible.

After treatment ,the patient should be followed up by the oncologist and undergo examinations, including the physical examination, determination of alpha-fetoprotein level and abdominal ultrasound. In the case of relapse, a second course of anti-tumor agents is recommend.

Read more
 

Sort by:

University Hospital Bonn

8.6/10 from 150 Votes

Chemotherapy of ovarian yolk sac tumor (1 course)

The key objective of the Department of Internal Medicine III is to create and offer optimal treatments for internal diseases on inpatient, partially inpatient and outpatient basis.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Bonn

Price 6278.00

University Hospital Cologne

8.7/10 from 82 Votes

Chemotherapy of ovarian yolk sac tumor (1 course)

The Department I for Internal Medicine of the University Hospital Cologne deals with the treatment of patients with various internal diseases. This includes in particular the following fields: Oncology, Hematology, Clinical infectology, Clinical immunology, Hemostasis, Intensive care.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Cologne

Price 6405.00

University Hospital Frankfurt

7.5/10 from 97 Votes

Chemotherapy of ovarian yolk sac tumor (1 course)

The Department of Hematology, Oncology, Hemostasis, Rheumatology and Infectology at the University Hospital Frankfurt specializes in the treatment of all diseases of the hymatopoietic system and solid tumors.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Frankfurt am Main

Price 7405.00

Charite University Hospital Berlin

9/10 from 95 Votes

Chemotherapy of ovarian yolk sac tumor (1 course)

The Charité Comprehensive Cancer Center integrates the clinical and research activities for all Charité departments and institutes dealing with Cancer. The director of the Charité Comprehensive Cancer Center is Prof. Dr. med. Ulrich Keilholz.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Berlin

Price 8769.00

University Hospital Heidelberg

9/10 from 57 Votes

Chemotherapy of ovarian yolk sac tumor (1 course)

The Department of Hematology, Oncology and Rheumatology at the Heidelberg University Hospital makes every effort to provide medical care of the highest quality to the patients with oncologic and rheumatologic diseases.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Heidelberg

Krankenhaus Nordwest

9.5/10 from 24 Votes

Chemotherapy of ovarian yolk sac tumor (1 course)

Department of Oncology and Hematology of Krankenhaus Nordwest offers a wide range of medical services, including diagnosis, therapy and treatment of oncological diseases or diseases closely associated with the circulatory system.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Frankfurt am Main

Price 5876.00

Städtisches Klinikum Schwabing

8.5/10 from 7 Votes

Chemotherapy of ovarian yolk sac tumor (1 course)

The Department of Hematology, Oncology, Immunology, Palliative Medicine, Infectious Diseases and Tropical Medicine in Schwabing treats all benign blood diseases, disorders of the immune and coagulation system, all forms of blood cancer, and the most of cancers.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Munich

Price 5707.00

RWTH University Hospital Aachen

8.7/10 from 41 Votes

Chemotherapy of ovarian yolk sac tumor (1 course)

The Department of Oncology, Hematology and Stem Cell Transplant provides patient care on both inpatient and outpatient basis. The focuses of the inpatient treatment are acute leukemia and high-dose chemotherapy followed by autologous blood stem cell transplantation.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Aachen

Price 5917.00

Alfried Krupp Hospital in Essen-Ruettenscheid

9.9/10 from 42 Votes

Chemotherapy of ovarian yolk sac tumor (1 course)

The main treatment areas of the Department of Internal Medicine I, headed by Prof. Dr. med. Thomas Budde, are invasive and non-invasive cardiac diagnostics and therapy of all cardiac diseases.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Essen

Price 5119.00

University Hospital Dusseldorf

9.9/10 from 71 Votes

Chemotherapy of ovarian yolk sac tumor (1 course)

The Department of Hematology, Oncology and Clinical Immunology at the University Hospital Dusseldorf provides treatment of patients with blood diseases, cancer and immune system diseases. The Department focuses on the treatment of malignant diseases of  blood, bone marrow and lymph nodes. .


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Duesseldorf

Price 7417.00

Hannover Medical School, MHH

9.8/10 from 43 Votes

Chemotherapy of ovarian yolk sac tumor (1 course)

The clinic of hematology, hemostasis, oncology and stem cell transplantation is a leading therapeutic clinic of the Medical Institute of Hannover for patients with solid tumor and systemic diseases, with other partially benign diseases of the hematopoietic system, as well as bleeding disorders.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Hannover

Price 6239.00

Städtisches Klinikum Neuperlach

9.8/10 from 11 Votes

Chemotherapy of ovarian yolk sac tumor (1 course)

The department of hematology and oncology diagnosed and treated malignant tumors. The therapeutic spectrum includes all medicamentous treating methodes including chemotherapy, antibody, immune and hormone therapy. Cancer patients benefit from interdisciplinary treatment.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Munich

Price 5872.00

Salem-Spital

9.6/10 from 29 Votes

Chemotherapy of ovarian yolk sac tumor (1 course)

Specialists in Department of Oncology of Salem-Spital are also involved in Swiss Tumor Institute STI. Among our partners there is a competenct network that offers real advantages in diagnosis and therapy of tumors and treats patients as the focus of its work.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Switzerland
location_searchingCity: Bern

Gummersbach District Hospital of the Klinikum Oberberg

9.6/10 from 23 Votes

Chemotherapy of ovarian yolk sac tumor (1 course)

The Department of Internal Medicine II at the Klinikum Oberberg in Gummersbach focuses on diagnosis and treatment of oncological and hematological diseases.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Gummersbach

Price 5287.00

University Hospital Halle (Saale)

9.5/10 from 78 Votes

Chemotherapy of ovarian yolk sac tumor (1 course)

The Department of Internal Medicine IV (Hematology and Oncology) covers the whole range of hematology and oncology. This includes prevention, diagnosis, therapy and post-operative care for cancer of all organs and blood.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Halle

Price 6100.00

UKGM Gießen

9.5/10 from 35 Votes

Chemotherapy of ovarian yolk sac tumor (1 course)

The department of internal medicine IV and V includes general internal medicine and a number of priority areas of this subject. The clinic offers a wide range of newest innovative treatments especially in the fields of medical oncology, hematology and palliative care.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Giessen

Price 5611.00