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Multimodality treatment of ovarian cancer with cytoreductive surgery and HIPEC (639353) | University Hospital Tuebingen - BookingHealth
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After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan and tomography of the abdominal organs. Based on the results of the examination, the physician will choose the surgical technique and the type of anesthesia. After that, preparation according to the preoperative standard will start.<\/p>\n\n<p style=\"text-align:justify\"><strong>Cytoreductive surgery<\/strong>&nbsp;begins with general anesthesia. The intervention is performed as open surgery, i.e. through the incision in the anterior abdominal wall, so that the surgeon can carefully examine the peritoneum and the surface of the abdominal organs. The surgeon removes affected by the malignant process ovaries, areas of the peritoneum and metastases in other internal organs. This stage of the operation can take several hours, since the overall effectiveness of the treatment depends on the completeness of the malignant tissues removal.<\/p>\n\n<p style=\"text-align:justify\">At the next stage of the operation, the surgeon inserts several catheters into the abdominal cavity. Through the catheters, a heated solution of a chemotherapy drug is pumped inside. The special system maintains the required temperature (42-43 degrees Celsius), pressure and circulation rate of the medicinal solution. The solution mechanically flushes out blood clots and remnants of malignant tissues, and a heated chemotherapy drug destroys micrometastases in internal organs and lymph nodes (micrometastases can&rsquo;t be detected by the naked eye).<\/p>\n\n<p style=\"text-align:justify\">After 1-1.5 hours, the chemotherapy drug is removed from the abdominal cavity and the abdominal cavity is washed with saline. 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After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan and tomography of the abdominal organs. Based on the results of the examination, the physician will choose the surgical technique and the type of anesthesia. After that, preparation according to the preoperative standard will start.<\/p>\n\n<p style=\"text-align:justify\"><strong>Cytoreductive surgery<\/strong>&nbsp;begins with general anesthesia. The intervention is performed as open surgery, i.e. through the incision in the anterior abdominal wall, so that the surgeon can carefully examine the peritoneum and the surface of the abdominal organs. The surgeon removes affected by the malignant process ovaries, areas of the peritoneum and metastases in other internal organs. This stage of the operation can take several hours, since the overall effectiveness of the treatment depends on the completeness of the malignant tissues removal.<\/p>\n\n<p style=\"text-align:justify\">At the next stage of the operation, the surgeon inserts several catheters into the abdominal cavity. Through the catheters, a heated solution of a chemotherapy drug is pumped inside. The special system maintains the required temperature (42-43 degrees Celsius), pressure and circulation rate of the medicinal solution. The solution mechanically flushes out blood clots and remnants of malignant tissues, and a heated chemotherapy drug destroys micrometastases in internal organs and lymph nodes (micrometastases can&rsquo;t be detected by the naked eye).<\/p>\n\n<p style=\"text-align:justify\">After 1-1.5 hours, the chemotherapy drug is removed from the abdominal cavity and the abdominal cavity is washed with saline. 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Multimodality treatment of ovarian cancer with cytoreductive surgery and HIPEC in University Hospital Tuebingen

University Hospital Tuebingen

Tuebingen, Germany
Program id # 639353
Doctor photo
Prof. Dr. med. Diethelm Wallwiener
Department of Adult and Pediatric Gynecology, Mammology, Obstetrics
Specialized in: adult and pediatric gynecology, mammology, obstetrics

The program includes:

  • Initial presentation in the clinic
  • clinical history taking
  • review of medical records
  • physical examination
  • laboratory tests:
    • complete blood count
    • general urine analysis
    • biochemical analysis of blood
    • TSH-basal, fT3, fT4
    • tumor markers 
    • inflammation indicators (CRP, ESR)
    • indicators of blood coagulation
  • abdominal ultrasound scan
  • CT scan/MRI or PET-CT of abdomen
  • preoperative care
  • cytoreductive surgery to remove visible tumors
    inside the abdomen and HIPEC
  • histological and immunohistochemical
    examination of removed tissues
  • symptomatic treatment
  • cost of essential medicines
  • nursing services
  • stay in the hospital with a full board
  • accommodation in a 2-bedroom ward
  • elaboration of further recommendations

How program is carried out

During the first visit, the physician will conduct a clinical examination and go through the results of the available diagnostic tests. After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan and tomography of the abdominal organs. Based on the results of the examination, the physician will choose the surgical technique and the type of anesthesia. After that, preparation according to the preoperative standard will start.

Cytoreductive surgery begins with general anesthesia. The intervention is performed as open surgery, i.e. through the incision in the anterior abdominal wall, so that the surgeon can carefully examine the peritoneum and the surface of the abdominal organs. The surgeon removes affected by the malignant process ovaries, areas of the peritoneum and metastases in other internal organs. This stage of the operation can take several hours, since the overall effectiveness of the treatment depends on the completeness of the malignant tissues removal.

At the next stage of the operation, the surgeon inserts several catheters into the abdominal cavity. Through the catheters, a heated solution of a chemotherapy drug is pumped inside. The special system maintains the required temperature (42-43 degrees Celsius), pressure and circulation rate of the medicinal solution. The solution mechanically flushes out blood clots and remnants of malignant tissues, and a heated chemotherapy drug destroys micrometastases in internal organs and lymph nodes (micrometastases can’t be detected by the naked eye).

After 1-1.5 hours, the chemotherapy drug is removed from the abdominal cavity and the abdominal cavity is washed with saline. After that, the surgeon removes the catheters and sutures the incision of the anterior abdominal wall.

After the completion of the operation, you will be transferred to the ward of the intensive care unit, under the round-the-clock supervision of doctors and nurses. In 1-3 days after the operation, your drains will be removed and you will be transferred to a regular ward for further recovery. The whole treatment takes 10-12 days on average.

Finally, the attending physician will evaluate the results of control examinations, schedule the date of discharge from the hospital and give you detailed recommendations for further follow-up and treatment.

Required documents

  • Medical records
  • MRI/CT scan (not older than 3 months)
  • Biopsy results (if available)

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About the department

According to the Focus magazine, the Department of Adult and Pediatric Gynecology, Mammology, Obstetrics at the University Hospital Tuebingen is included in the ranking of the top German departments specializing in obstetrics and breast cancer treatment! 

The department offers the full range of diagnostics and treatment of diseases of the female reproductive system, breast pathologies. Also, the specialists of the department provide a comprehensive management of pregnancy, childbirth and postpartum care for both mother and child. Key attention is paid to the treatment of female genital cancers, as well as breast cancer treatment. For this purpose, the department has all the modern therapeutic techniques, as well as its our own innovative developments by the department doctors.

The department is headed by Prof. Dr. med. Diethelm Wallwiener. For almost 25 years, the specialist has been guarding women's health, treating the full range of gynecologic diseases and breast pathologies. The obstetrician-gynecologist also does everything to ensure that the pregnancy and childbirth of his patients are as safe as possible. Dr. Wallwiener is an honorary member of the National College of French Gynecologists and Obstetricians (CNGOF), the European Society for Gynecological Endoscopy (ESGE), and the Royal College of Obstetricians and Gynecologists (RCOG). Almost 250 of his publications are presented on Internet resources, and he is also often invited to medical conferences to read reports.

The medical team of the department has long experience in the surgical treatment of gynecological diseases in women. The surgeons specialize in performing both highly complex interventions and sparing minimally invasive procedures. It should be noted that the treatment of many diseases is carried out within the framework of specialized centers, for example, such pathologies include endometriosis, cervical dysplasia, pelvic diseases, breast cancer, etc. The department has an excellent reputation in the treatment of oncopathology of the female genital organs, breast cancer, and also was certified by the German Cancer Society.

In the field of obstetrics, the patients are provided with high-quality prenatal diagnostics, comprehensive counseling on all issues of pregnancy, childbirth and the postpartum period. The childbirth takes place in the modern delivery rooms, equipped with everything necessary for a safe childbirth. Also, the department offers courses for the future parents.

The service range of the department includes:

Outpatient surgery
  • Laparoscopy
  • Hysteroscopy
  • Uterus scraping
  • Conization of the cervix
  • Laser therapy
  • Diagnostics in fertility disorders
Diagnostics and treatment of pelvic diseases
  • Suspension therapy
  • Urinary incontinence treatment using TVT or TVT-O procedures
  • Drug therapy
  • Electrostimulation
  • Biofeedback technique
  • Pessary treatment
  • Special exercise to strengthen the pelvic floor muscles
Diagnostics and treatment of breast cancer
  • Mammography screening
  • Imaging diagnostics and early detection of the pathology
  • Minimally invasive diagnostics (biopsy)
  • Drug therapy (for example, antihormonal therapy)
  • Radiation therapy
  • Surgical treatment, including plastic reconstructive surgery to achieve the optimal aesthetic result
  • Psychological care
  • Genetic counseling
Obstetric services
  • Comprehensive management of pregnancy, including high-risk pregnancy
  • Prenatal diagnostics
    • Screening (first, second and third trimester)
    • Invasive diagnostics and therapy (for example, amniocentesis, chorionic villus sampling or umbilical cord puncture)
    • Ultrasound examinations
    • Detection of fetal malformations in the womb
  • Delivery
  • Postpartum care for both mother and baby
  • Courses for the future parents
  • Counseling on baby care
Diagnostics and treatment of gynecologic cancers
  • Uterine cancer
  • Cervical cancer
  • Ovarian cancer
  • Vulvar cancer
  • Vaginal cancer
  • Fallopian tube cancer
  • Recurrent oncological processes and metastases
    • Targeted therapy
    • Antibody therapy
    • Hormone therapy
    • Radiation therapy
    • Chemotherapy
    • Surgical treatment
    • Treatment within the framework of clinical trials
    • Psycho-oncological care
Diagnostics and treatment of cervical dysplasia
  • Histological examination
  • Colposcopy
  • Individually adapted laser therapy
  • Conization of the cervix
Diagnostic and treatment of endometriosis (conservative and surgical methods) 
Diagnostics and treatment of gynecologic problems in children and adolescents
  • Diseases in newborns before puberty
  • Diseases arising after puberty
    • Violations of the menstrual cycle (for example, severe pain during menstruation, lack of menstruation)
    • Infections
    • Delayed puberty and impaired puberty
    • Contraception counseling
    • Hormonal disorders (for example, polycystic ovary syndrome)
    • Congenital adrenal gland disorder
    • Malformations of the internal and external genital organs
    • Ovarian cysts and tumors
    • Pathological breast changes
    • Ullrich-Turner syndrome and other genetic abnormalities
    • Consultation on HPV and vaccination against cervical cancer
Diagnostics and treatment of fertility
  • Comprehensive diagnostics
  • In vitro fertilization (IVF)
  • Intracytoplasmic sperm injection (ICSI)
Gynecological surgery
  • Minimally invasive surgery
  • Cancer surgery (many operations are endoscopic)
  • Plastic surgery (for example, after breast cancer treatment)
  • Conventional surgery (access through the abdominal cavity or vagina)
  • Surgical treatment of stress urinary incontinence (TVT or TVT-O procedures)
Diagnostics and treatment of rare genital malformations 
Other medical services 

Curriculum vitae

  • 1974 Study of Physics at the Saarland University.
  • 1975 Study of Medicine at the Saarland University.
  • 1981 Admission to medical practice.
  • 1982 Doctoral Degree.
  • 1982 - 1988 Research Assistant at the Department of Gynecology and Department of Pediatrics, Division of Interdisciplinary Intensive Care of the University Hospitals in Homburg
  • 1988 - 1998 Senior Physician at the Department of Gynecology, University Hospital Heidelberg.
  • 1989 Certified as a Physician in Obstetrics and Gynecology.
  • 1990 Habilitation.
  • 1996 Appointed as a Visiting Professor.
  • Since 1998, Chair of Gynecology (C4 Professor), University Hospital Tuebingen.

Clinical and Scientific Focuses

  • Surgical/experimental gynecology.
  • Surgical oncology.
  • Fertility as part of reproductive medicine.
  • Gynecologic oncology.
  • High-risk obstetrics.

Memberships in Professional Societies

  • German Society of Senology (at present Acting President of the Society).
  • European Society for Gynecological Endoscopy and Innovative Surgery (ESGE).
  • German Cancer Society, Representative of the Working Association "Gynecologic Oncology" (AGO) in the "Clinical Trials" Commission, Quality Seal A.
  • German Society of Gynecology and Obstetrics (DGGG), Guidelines Commission of the AGO.
  • German Society of Laser Medicine, Board Member.

Photo of the doctor: (c) Universitätsklinikum Tübingen

Sources:

Universitätsklinikum und Medizinische Fakultät Tübingen

PubMed, National Library of Medicine


About hospital

According to the prestigious medical publication Focus, the University Hospital Tuebingen ranks among the top five German hospitals! 

The hospital was founded in 1805, therefore it is proud of its long history, unique experience, and outstanding achievements in the field of medical care, as well as research and teaching activities. Nowadays, it is one of the most advanced medical institutions, which provides a wide range of general and highly specialized medical services. The hospital combines the state-of-art medical technologies in the field of diagnostics and the very latest treatment methods of a wide range of diseases.

The hospital has 17 specialized departments, which cover almost all fields of modern medicine and contribute to the top-class medical service in Germany. It treats about 367,000 outpatients and 74,000 inpatients annually. This testifies to the high authority of the hospital at the national and international medical arena. This is the first German hospital, which confirmed the high quality of healthcare and the effectiveness of service with a KTQ certification (in 2009).

Photo: (с) depositphotos

Accommodation in hospital

Patients rooms

The patients of the University Hospital Tuebingen live in comfortable single and double rooms with an ensuite bathroom equipped with a shower and toilet. The beds in the patient rooms are equipped with orthopedic mattresses that promote good and full sleep. There is a TV in the room, and it is also possible to connect a smartphone or laptop to the Internet. In addition, there is enough space in the patient room to receive 2-3 guests without inconvenience for the second patient.

The enhanced-comfort rooms include a hairdryer, heated towel rail, a large mirror, a direct dial telephone, a flat-screen satellite TV, a writing desk, free Internet access, a mini-bar and a refrigerator.

Meals and Menus

The patients of the hospital are offered tasty and healthy three meals a day: breakfast, lunch and dinner. Breakfast is served as a buffet, while for lunch and dinner there is a choice of several menus. Also, if desired, the patient will be provided with an individual menu. There are several cafes and cafeterias on the territory of the hospital, where one can have a tasty meal or enjoy a cup of coffee, tea and dessert.

Further details

Standard rooms include:

Toilet
Shower
Wi-Fi
TV

Religion

Religious services are available upon request.

Accompanying person

During the inpatient program, an accompanying person can stay with you in a patient room or in a hotel of your choice.

Hotel

During the outpatient program, you can stay in a hotel of your choice. Our managers will help you choose the most suitable option for you.