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University Hospital Muenster

9.8/10 from78 Votes

The University Hospital Muenster is one of the most respected multi-field medical centers in Germany. It consists of more than 30 departments and numerous research institutes and centers. Every year over 58,000 inpatients are treated here and nearly 475,000 patients receive medical care on the outpatient basis.

Brain AV-Malformation (AVM) diagnosis
2871
Treatment of av-malformation of brain using platinum coils embolization (coiling)
18560
Treatment of brain av-malformation with partial resection and coiling
22080
location_onCountry: Germany
location_searchingCity: Muenster
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Charite University Hospital Berlin

9/10 from95 Votes

Being the medical school for both Humboldt University and Free University of Berlin and having a long experience, the Charite Hospital has gained wide recognition. It is regarded as one of the most research-intensive medical facilities in Germany and the largest university medical center in Europe.

Brain AV-Malformation (AVM) diagnosis
5591
location_onCountry: Germany
location_searchingCity: Berlin
certificatecertificatecertificatecertificatecertificatecertificatecertificate

University Hospital Rechts der Isar of the Munich Technical University

10/10 from70 Votes

The Rechts der Isar Hospital is the University Hospital of the Technical University of Munich. There is intensive cooperation between the research facilities of the TU and the hospital in numbers of areas.

Brain AV-Malformation (AVM) diagnosis
2889
location_onCountry: Germany
location_searchingCity: Munich
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University Hospital of the Ludwig-Maximilians-University Munich (LMU)

9.2/10 from40 Votes

The Hospital of the Ludwig-Maximilians-University (LMU) Munich is a center of high-end medicine, medical innovation and medical and technical progress, which enables an individual and safe patient care.

Brain AV-Malformation (AVM) diagnosis
3643
location_onCountry: Germany
location_searchingCity: Munich
certificatecertificatecertificatecertificate

University Hospital Frankfurt am Main

10/10 from97 Votes

The University Hospital Frankfurt is part of the Johann Wolfgang Goethe University Frankfurt am Main. The hospital was founded in 1914 and today it is a famous German medical institution with rich traditions. The hospital treats about 49,000 inpatients and 220,000 outpatients every year.

Brain AV-Malformation (AVM) diagnosis
2851
location_onCountry: Germany
location_searchingCity: Frankfurt am Main
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Sana Hospital Duisburg

9.8/10 from5 Votes

The Sana Hospital Duisburg is a maximum care medical center with 678 beds and 17 specialized departments. With the very latest innovations and high quality patient care, the clinic works for the benefit of a person and their health. The hospital ranks among the leading clinics in the region.

Brain AV-Malformation (AVM) diagnosis
2715
Treatment of av-malformation of brain using platinum coils embolization (coiling)
17382
Treatment of brain av-malformation with partial resection and coiling
19588
location_onCountry: Germany
location_searchingCity: Duisburg
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HELIOS Clinic Krefeld

9.7/10 from38 Votes

Founded in 2014, the HELIOS Clinic Krefeld is one of the most modern medical facilities in Germany today. A team of highly qualified specialists, innovative medical equipment and comfortable accommodation conditions – the clinic has everything to make the treatment run smoothly and efficiently.

Brain AV-Malformation (AVM) diagnosis
2554
location_onCountry: Germany
location_searchingCity: Krefeld

Vivantes Neukölln Hospital Berlin

10/10 from23 Votes

The Vivantes Neukölln Hospital is the maximum care hospital and one of the largest healthcare facilities in Berlin.   There are more than 20 specialized departments and centers, including pediatric departments. In total, the hospital has 1,200 beds.

Brain AV-Malformation (AVM) diagnosis
3620
Treatment of av-malformation of brain using platinum coils embolization (coiling)
21720
Treatment of av-malformation of brain using platinum coils embolization (coiling)
21975
location_onCountry: Germany
location_searchingCity: Berlin

Vivantes Humboldt Hospital Berlin

9.7/10 from23 Votes

An academic clinic of the university medical complex Charité, the Vivantes Humboldt Hospital is one of the largest specialized medical institutions in Berlin.

Treatment of av-malformation of brain using platinum coils embolization (coiling)
21648
Treatment of brain av-malformation with partial resection and coiling
24810
location_onCountry: Germany
location_searchingCity: Berlin

Academic Hospital Asklepios Barmbek Hamburg

9.5/10 from23 Votes

As an Academic Hospital of the University of Hamburg, the Asklepios Barmbek Hospital offers a wide range of medical services in the field of conservative and surgical treatment. The hospital was opened in 2005 and today it is one of the best and modern medical centers in Europe.

Treatment of av-malformation of brain using platinum coils embolization (coiling)
18596
Treatment of brain av-malformation with partial resection and coiling
22099
location_onCountry: Germany
location_searchingCity: Hamburg

Alfried Krupp Hospital in Essen-Ruettenscheid

7.4/10 from42 Votes

With 900 beds and approximately 2,050 employees in two branches, the Alfried Krupp Hospital is one of the larger hospital institutions in Essen.

Brain AV-Malformation (AVM) diagnosis
2841
Treatment of av-malformation of brain using platinum coils embolization (coiling)
18322
Treatment of brain av-malformation with partial resection and coiling
22412
location_onCountry: Germany
location_searchingCity: Essen
certificate

Academic Hospital Schwabing Munich

8.5/10 from7 Votes

The Schwabing Clinic is a modern medical facility with a high level of service. The clinic has high-tech modern equipment, making it one of the best hospitals not only in Germany but also in Europe. There are comfortable single and double rooms with shower and toilet, TV, telephone and radio.

Brain AV-Malformation (AVM) diagnosis
2615
location_onCountry: Germany
location_searchingCity: Munich

Tel Aviv Sourasky Medical Center

9.9/10 from23 Votes

The Tel Aviv Sourasky Medical Center (Ichilov) is the second largest and one of the most advanced healthcare and research institutions in Israel. Founded in 1961, it still enjoys popularity among the local population and draws thousands of international patients.

Brain AV-Malformation (AVM) diagnosis
0.00
location_onCountry: Israel
location_searchingCity: Tel Aviv

University Hospital Cologne

9.8/10 from82 Votes

The University Hospital Cologne is included in the Focus magazine rating of top German hospitals 2017 and offers patients first-class medical care meeting the latest medical advancements.

Brain AV-Malformation (AVM) diagnosis
2523
location_onCountry: Germany
location_searchingCity: Cologne
certificatecertificatecertificate

Rambam Health Care Campus Haifa

9.8/10 from23 Votes

Rambam Health Care Campus is the largest and the most advanced hospital in Northern Israel. Founded in 1938, the medical center has a long history and a rich experience in providing comprehensive medical services in all medical specialties.

Brain AV-Malformation (AVM) diagnosis
0.00
location_onCountry: Israel
location_searchingCity: Haifa

St. Vincentius Clinic Karlsruhe

9.8/10 from23 Votes

The St. Vincentius Clinic is the largest multidisciplinary medical institution and academiс hospital of the Albert Ludwig University of Freiburg. Treatment and diagnosis of patients is conducted by doctors with a scientific degree. They are introducing the latest progressive techniques.

Treatment of av-malformation of brain using platinum coils embolization (coiling)
17534
Treatment of brain av-malformation with partial resection and coiling
19743
location_onCountry: Germany
location_searchingCity: Karlsruhe

About the disease

Av-malformation of brain is an abnormal tangle of abnormal blood vessels that connect the arteries and veins in the area of the brain. Overall, arteries are responsible for the transportation of blood from heart to brain Moreover, this blood must be rich in oxygen, that's why arteries contain special oxygen-cells. Blood which does not have an oxygen is carried to lungs and back to the heart, because brain can naturally accept only oxygen-cells blood. In case av-malformation this process of blood interchange becomes disrupted. It means that blood with oxygen and blood without oxygen mix and create chaos. Av-malformation can develop in any part of the body, but most often if effects brain and spine. Brain av-malformation is very rare disease with 1% of world population having it.   

Cause of brain malformation still remains unknown. It is a congenital disease, but it manifests itself when a person is in his adulthood. It is not transmitted genetically, which means that this disease appears absolutely randomly.

First symptoms of av-malformation may appear at the age of 11-12. Some patients begin to feel the rupture of brain tissues only when they are 40 or 50. Symptoms gradually build up and become more and more severe over the course of several years. Sometimes brain malformation manifests itself during pregnancy, when a woman suddenly experiences hemorrhage of brain tissues and severe headaches. Nevertheless, brain malformation is more common in men that women. According to Brain Foundation.org, which is a medical site, if the first symptom of this disease was hemorrhage, it can become fatal in 10%. That`s why timely treatment is so important.

Symptoms

  • Hemorrhage of the brain vessels
  • Rupture of certain brain tissues
  • Constant pain in one specific area of the head
  • Some muscles become weak and can not function as before
  • Body becomes numb
  • Patient may lose vision partially or fully
  • Coordination becomes unsteady and unbalanced

The most dangerous type of brain malformations is called the Galen defect. This defect is inborn and it can appear either after the birth or during the first months of baby`s life. If the person has the Galen effect, the blood vessels start to accumulate in his rain to the point when the head swells enormously. The swelling is especially seen on the scalp and near the neck. Because of this swelling brain experiences compression and the fluid, which was earlier directed in specific areas of the brain, starts to freely flow in any part of the hemisphere. The Galen defect may also cause various heart diseases, because the blood does not return properly back to the heart.

Diagnosis

The most common diagnostic method for this disease is brain scan. Doctors may also use the cerebral arteriography during which the location of arteries is revealed. Magnetic imaging can also be quite effective. It helps to obtain the microscopic image of the brain with its smallest deviations from the norm. It can also detect if there`s an excessive amount of blood in the brain.

Treatment

The most dangerous complication of brain malformation is the brain hemorrhage, that`s why  treatment of malformation mostly aims to prevent or stop bleeding and future seizures. Medicine in this case may only alleviate the pain and reduce the number of headaches, that's why it's important to undergo surgery. There are such surgical options:

  • Partial resection and coiling, when a doctor inserts catheter into hip vessel to pack coils  into aneurysm. It is done to prevent blood flow from inundating aneurysm. The doctor can track the catheter through the X-Ray which shows its exact location. Coiling may reduce size of the malformation and prevent further bleeding.
  • Platinum coils embolization (coiling) is a more modern procedure, which also uses coils to hamper blood flow, but in this case doctor uses coils made of platinum.
  • Resection of AVM. During the resection the surgeon makes an incision and opens a skull. After that he identifies the exact location of the damaged brain tissue and removes the malformation around this. If the malformation is located too deep, neurosurgeon simply can not reach it and in that case he can use other treatment options.
  • Radiosurgery. During the radiosurgery the doctors use radiation to destroy the malformation. In this case the irradiation scatters damaged cells. If malformation is too big, it is impossible to make the cells vanish. The biggest drawback of radiosurgery is that the cells, which formed the malformation before, may gather again and create even a bigger problem. Moreover, the irradiation has a long line of serious side effects: the immune system of the person weakens, he loses his hair, his skin worsen and general health condition deteriorates. That`s why it is more preferable to undergo the surgery. Recent advances in medicine allow the doctors to almost diminish the malformation with the microsurgery, which can reach the most distant cells and prevent their future growth. The most modern type of radiosurgery is Gamma Knife, which is less traumatic than surgery.

After treatment was finished patients need to undergo the regular check-ups and to maintain the healthy lifestyle. For instance, patients are advised to undergo course of physical therapy and to avoid any stressful situations in future, which can cause the hemorrhage of the bain. Patients also need to regularly control their blood pressure. If it is high, they are prescribed drugs that can normalize the blood flow and prevent hypertension.




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