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Treatment of Dermatofibrosarcoma in Germany

Due to the difficulties associated with the organization of treatment in Turkey, Switzerland, South Korea and India, we are not currently processing requests to these regions.

If you are interested in treatment in Germany, please leave a request and our specialists will contact you as soon as possible.

 

Cost for treatment

Diagnostic for dermatofibrosarcoma
970
Micrographic surgery for dermatofibrosarcoma
2107
Radiotherapy for dermatofibrosarcoma
11755

University Hospital of Ludwig Maximilian University of Munich

10/10
location_onGermany, Munich

Department of Adult and Pediatric Dermatology, Allergology

According to the Focus magazine, the University Hospital of Ludwig Maximilian University of Munich is regularly ranked among the best medical institutions in Germany! The hospital is the largest multidisciplinary medical facility, as well as a leading research and training center in Germany and Europe. The hospital is proud of i
Diagnostic for dermatofibrosarcoma
3716
Micrographic surgery for dermatofibrosarcoma
6670
Radiotherapy for dermatofibrosarcoma
22814

HELIOS Clinic Krefeld

9.7/10
location_onGermany, Krefeld

Department of Dermatology and Venereology

Founded in 2014, the HELIOS Clinic Krefeld is one of the most modern medical facilities in Germany today. A team of highly qualified specialists, innovative medical equipment and comfortable accommodation conditions – the clinic has everything to make the treatment run smoothly and efficiently. Having crossed the threshold
Diagnostic for dermatofibrosarcoma
3251
Micrographic surgery for dermatofibrosarcoma
5781
Radiotherapy for dermatofibrosarcoma
18736

University Hospital Frankfurt am Main

10/10
location_onGermany, Frankfurt am Main

Department of Dermatology, Venereology and Allergology

According to the reputable Focus magazine, the University Hospital Frankfurt am Main ranks among the top German medical facilities! The hospital was founded in 1914 and today is a well-known German medical facility, which combines rich traditions and scientific innovations. A medical team of more than 6,500 employees cares about
Diagnostic for dermatofibrosarcoma
3394
Micrographic surgery for dermatofibrosarcoma
5969
Radiotherapy for dermatofibrosarcoma
17536

University Hospital Erlangen

9.1/10
location_onGermany, Erlangen

Department of Dermatology, Allergology and Andrology

According to the Focus magazine, University Hospital Erlangen ranks among the best medical facilities in Germany! The hospital is one of the leading healthcare facilities in Bavaria and offers top-class medical care distinguished by the close intertwining of clinical activities with research and training of medical students. The
Diagnostic for dermatofibrosarcoma
3488
Micrographic surgery for dermatofibrosarcoma
6429
Radiotherapy for dermatofibrosarcoma
21402

University Hospital RWTH Aachen

8.7/10
location_onGermany, Aachen

Department of Dermatology and Allergology

According to the prestigious Focus magazine, the University Hospital RWTH Aachen ranks among the top German hospitals! As a maximum care university medical facility, the hospital guarantees patients first-class medical services combined with a respectful and human attitude. The hospital integrates all the modern options for the
Diagnostic for dermatofibrosarcoma
3592
Micrographic surgery for dermatofibrosarcoma
6782
Radiotherapy for dermatofibrosarcoma
22566

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Department of Adult and Pediatric Dermatology, Venereology and Allergology

According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! The hospital is one of the largest and leading university medical complexes in Europe. The hospital in Germany provides modern diagnostics and treatment of patients, a
Diagnostic for dermatofibrosarcoma
4651
Micrographic surgery for dermatofibrosarcoma
8616
Radiotherapy for dermatofibrosarcoma
22543

University Hospital Hamburg-Eppendorf

9.2/10
location_onGermany, Hamburg

Department of Dermatology and Venereology

According to the Focus magazine, the University Hospital Hamburg-Eppendorf ranks among the top ten hospitals in Germany! Since its foundation in 1889, the hospital has taken a leading position in the European medical arena and still occupies it until today. A highly competent medical team of more than 11,000 employees takes care
Diagnostic for dermatofibrosarcoma
4105
Micrographic surgery for dermatofibrosarcoma
7827
Radiotherapy for dermatofibrosarcoma
17778

University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of Dermatology and Allergology

The University Hospital Ulm started its activities 35 years ago and during this time it has become one of the most prestigious medical institutions in Europe. The hospital is famous for its numerous discoveries and the world-class achievements in medicine and pharmaceuticals. The medical facility has 29 specialized departments a
Diagnostic for dermatofibrosarcoma
3428
Micrographic surgery for dermatofibrosarcoma
6481
Radiotherapy for dermatofibrosarcoma
21426

University Hospital Würzburg

9.2/10
location_onGermany, Würzburg

Department of Adult and Pediatric Dermatology, Venereology and Allergology

According to the Focus magazine in 2019, the University Hospital Würzburg ranks among the top national German hospitals! The hospital is one of the oldest medical facilities in Germany. The centuries-old traditions of first-class treatment are combined with the very latest achievements of modern evidence-based medicine and
Diagnostic for dermatofibrosarcoma
3232
Micrographic surgery for dermatofibrosarcoma
6093
Radiotherapy for dermatofibrosarcoma
17530

University Hospital Muenster

9.8/10
location_onGermany, Muenster

Department of Adult and Pediatric Dermatology, Venereology

According to the Focus magazine, the University Hospital Muenster ranks among the top German hospitals! The hospital belongs to the most prestigious medical institutions in Germany. The hospital is distinguished by a high professionalism of its doctors, state-of-the-art technological equipment and the availability of the most ad
Diagnostic for dermatofibrosarcoma
3286
Micrographic surgery for dermatofibrosarcoma
6001
Radiotherapy for dermatofibrosarcoma
17945

University Hospital Bonn

9.2/10
location_onGermany, Bonn

Department of Dermatology and Allergology

According to the authoritative Focus magazine, the University Hospital Bonn ranks among the top ten medical facilities in Germany! The hospital was opened on January 1, 2001, although in fact it inherits the medical facility, which operated at the Faculty of Medicine of the University of Bonn. The hospital in Germany combin
Diagnostic for dermatofibrosarcoma
3633
Micrographic surgery for dermatofibrosarcoma
6741
Radiotherapy for dermatofibrosarcoma
17561

University Hospital Heidelberg

9.8/10
location_onGermany, Heidelberg

Department of Adult and Pediatric Dermatology

According to Focus magazine, the University Hospital Heidelberg ranks among the top five hospitals in Germany! The hospital is one of the most advanced and reputable medical institutions not only in Germany, but throughout Europe. There are more than 43 specialized departments and 13 medical institutes, which cover all fields of
Diagnostic for dermatofibrosarcoma
0
Micrographic surgery for dermatofibrosarcoma
0
Radiotherapy for dermatofibrosarcoma
0

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of Dermatology and Venereology

According to the prestigious Focus magazine, the University Hospital Halle (Saale) ranks among the top German medical facilities! The history of the hospital has more than 300 years, and during this time it managed to earn an excellent reputation not only in Germany, but throughout the world. The hospital positions itself as a s
Diagnostic for dermatofibrosarcoma
3350
Micrographic surgery for dermatofibrosarcoma
6024
Radiotherapy for dermatofibrosarcoma
17871

University Hospital Jena

8.9/10
location_onGermany, Jena

Department of Dermatology

According to the prestigious Focus magazine, the University Hospital Jena regularly ranks among the top German medical facilities! The hospital has positioned itself as a multidisciplinary medical facility with a long history of more than 200 years. Since its foundation, the hospital has been constantly developing and modernizin
Diagnostic for dermatofibrosarcoma
0.00
Micrographic surgery for dermatofibrosarcoma
6783
Radiotherapy for dermatofibrosarcoma
17962

University Hospital Essen

9.6/10
location_onGermany, Essen

Department of Dermatology

According to the authoritative Focus magazine the University Hospital Essen ranks among the top German hospitals! With 27 specialized departments and 24 institutes, the hospital in Germany is a maximum care medical facility. The hospital has 1,300 beds for inpatient treatment. A highly qualified medical team of more than 6,000 e
Diagnostic for dermatofibrosarcoma
3416
Micrographic surgery for dermatofibrosarcoma
6154
Radiotherapy for dermatofibrosarcoma
17801

University Hospital Marburg UKGM

8.6/10
location_onGermany, Marburg

Department of Dermatology and Allergology

The University Hospital Marburg UKGM offers patients modern diagnostics and comprehensive therapy at the international level. As a maximum care hospital, the medical facility specializes in all fields of modern medicine ranging from ophthalmology to traumatology and dentistry. The main areas of specialization of the hospital are
Diagnostic for dermatofibrosarcoma
3172
Micrographic surgery for dermatofibrosarcoma
5755
Radiotherapy for dermatofibrosarcoma
21195
| from Booking Health GmbH

Dermatofibrosarcoma protuberans (DFSP) is a rare soft tissue tumor affecting the skin and subcutaneous adipose tissue. Physically, the tumor is a slowly growing solid plaque. It most often develops on the torso in young people. A diagnosis is made by doing a skin biopsy. In Germany, the vast majority of cases are successfully treated. Clinics in Germany prefer the Mohs surgery, as it provides a 7-fold reduction in the risk of tumor recurrence compared to wide excision.

Content

  1. Mohs surgery
  2. Wide excision
  3. Drug therapy
  4. Radiation therapy

In Germany, the main treatment method is the Mohs microsurgery. The operation provides a low risk of recurrence and ensures excellent aesthetic results. After surgery, radiation therapy or drug therapy with tyrosine kinase inhibitors may be required.

You can undergo treatment in the following hospitals: University Hospital of Ludwig Maximilian University of Munich, University Hospital Frankfurt am Main, HELIOS Clinic Krefeld.

Please leave your request for the treatment of dermatofibrosarcoma on the Booking Health website, and our specialists will contact you immediately. They will help you select a clinic and a doctor, apply for a visa, get to the clinic, get medical insurance and communicate with doctors in the same language (interpreting services). Upon completing treatment and returning to your native country, you will be able to receive remote consultations from the attending physician until complete recovery.

Mohs surgery

 

Mohs micrographic surgery is considered the best treatment for dermatofibrosarcoma. This is a complex operation that is not performed in all medical centers. At the same time, it is the main one in German clinics.

The essence of the surgical technique is the multi-stage removal of the tumor, with a constant assessment of the state of the resection margin.

The doctor performs a tumor resection with minimal capture of the adjacent tissues. The material is then sent to the laboratory to assess the resection margin. After receiving the results, the doctor continues to cut the flaps, but only in the direction in which tumor cells are found. After each such stage, a repeated histological examination is carried out.

As a result, the operation can take several hours. It is continued until the resection margins are clear. Such an operation is more sparing and provides better aesthetic outcomes since the doctor does not have to remove tissue with a "reserve". This is especially important when the neoplasm is localized in areas where resection of a significant amount of tissue can lead to functional disorders.

Another advantage of the Mohs surgery is the low risk of tumor recurrence. It is associated with total histopathological control of the resection margin during surgery.

Wide excision

 

Wide excision is rarely used in developed countries, but this method is often used in countries with poorly developed medicine.

The essence of the surgical intervention is that the tumor is removed with an indentation of 2 to 4 cm from the visible margin of the neoplasm. The indentation depends on both the size of the tumor and its location, as well as on the requirements for the functional and aesthetic outcomes of the surgery.

After a wide local excision, the recurrence rate reaches 7,3%. At the same time, in the case of micrographic Mohs surgery, the probability of tumor recurrence is only 1%.

Dermatofibroma very rarely metastasizes to the lymph nodes, so in most cases, patients do not require additional surgical intervention on the lymphatic collector. As a result of refusing to remove lymph nodes, the treatment of the disease becomes less traumatic, the risk of complications is reduced, and the duration of oncological rehabilitation is reduced.

Drug therapy

 

The treatment of dermatofibrosarcoma in Germany involves using an oral tyrosine kinase inhibitor. Most patients do not require drug therapy. It is used for the following forms of dermatofibrosarcoma:

  • recurrent (returning after primary treatment)
  • unresectable (not subject to surgical removal)
  • metastatic

The best response to the treatment is achieved in patients with t(17;22) translocation. This genetic disorder is detected by the results of molecular biological diagnostics. Fluorescence in situ hybridization (FISH) or reverse transcription polymerase chain reaction (RT-PCR) is used in Germany.

The course of treatment lasts 6 months, and it is effective in two-thirds of patients.

Radiation therapy

 

In the case of dermatofibrosarcoma, radiation therapy is not very common. This is due to the fact that surgery is enough to cure this disease in most patients. The areas of application of radiation therapy are as follows:

  • after surgery – in case of high risk of recurrence
  • destruction of the recurrent tumor

After surgery, most recurrences occur within the first 3 years. Therefore, the most accurate monitoring of patients is carried out during these periods. They are examined every 3 months in the first year and every 6 months in the next 2 years. Then the frequency of examinations can be reduced to 1 time in 12 months. With a high risk of recurrence, the list of diagnostic tests includes a chest CT scan.

Patients who want to undergo diagnostics and treatment of dermatofibrosarcoma in Germany can book a medical care program via the international medical tourism agency Booking Health. When using this service, prices will be lower for you due to the lack of additional coefficients for foreign patients. The cost of treatment is guaranteed not to increase, as you will receive insurance coverage up to 200,000 euros. On our website, you can find out the price for surgical interventions and conservative procedures in different clinics in Germany and book your treatment on the most suitable dates. The Booking Health specialists will select a clinic for you and take care of the arrangement of your trip.

 

Authors: 

The article was edited by medical experts, board certified doctors Dr. Nadezhda Ivanisova and Dr. Sergey Pashchenko. For the treatment of the conditions referred to in the article, you must consult a doctor; the information in the article is not intended for self-medication!

 

Sources:

MedlinePlus

Sience Direct

PubMed




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