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Treatment of Ovarian Teratoma

Due to the difficulties associated with the organization of treatment in Turkey, Switzerland, South Korea and India, we are not currently processing requests to these regions.

If you are interested in treatment in Germany, please leave a request and our specialists will contact you as soon as possible.

 

Cost for treatment

Diagnosis of ovarian teratoma
 from  584
Chemotherapy of teratoma with Cisplatin (1 course)
 from  1620
Surgery treatment of ovarian teratoma
 from  2130

University Hospital Rechts der Isar Munich

9.8/10
location_onGermany, Munich

Department of Gynecology, Mammology, Obstetrics and Perinatal Medicine

According to the prestigious FOCUS magazine, the University Hospital Rechts der Isar Munich ranks among the Germany's top medical institutions! Founded in 1834, the hospital combines long traditions and the very latest achievements of modern medicine. The medical facility includes 33 specialized departments, 20 interdiscipli
Diagnosis of ovarian teratoma
2053
Chemotherapy of teratoma with Cisplatin (1 course)
5755
Surgery treatment of ovarian teratoma
6708

University Hospital Tuebingen

9.2/10
location_onGermany, Tuebingen

Department of Adult and Pediatric Gynecology, Mammology, Obstetrics

According to the prestigious medical publication Focus, the University Hospital Tuebingen ranks among the top five German hospitals! The hospital was founded in 1805, therefore it is proud of its long history, unique experience, and outstanding achievements in the field of medical care, as well as research and teaching activitie
Diagnosis of ovarian teratoma
1823
Chemotherapy of teratoma with Cisplatin (1 course)
5533
Surgery treatment of ovarian teratoma
6683

Leverkusen Clinic

10/10
location_onGermany, Leverkusen

Department of Gynecology, Urogynecology, Mammology and Obstetrics

The Leverkusen Clinic is a progressive provider of high-quality diagnostic and therapeutic services in Germany. The medical facility is an Academic Hospital of the University of Cologne, and also maintains close cooperation with the Rhine Research Center. The medical facility houses 12 specialized departments, as well as numerou
Diagnosis of ovarian teratoma
1792
Surgery treatment of ovarian teratoma
6219

University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of Obstetrics, Adult and Pediatric Gynecology

The University Hospital Ulm started its activities 35 years ago and during this time it has become one of the most prestigious medical institutions in Europe. The hospital is famous for its numerous discoveries and the world-class achievements in medicine and pharmaceuticals. The medical facility has 29 specialized departments a
Diagnosis of ovarian teratoma
1955
Chemotherapy of teratoma with Cisplatin (1 course)
5526
Surgery treatment of ovarian teratoma
6595

University Hospital Carl Gustav Carus Dresden

9.1/10
location_onGermany, Dresden

Department of Adult and Pediatric Gynecology, Mammology and Obstetrics

According to the prestigious Focus magazine, the University Hospital Carl Gustav Carus Dresden is among the top three hospitals in Germany! The hospital is the embodiment of the standards of modern high-quality medicine. Since the hospital positions itself as a maximum care medical facility, it represents all medical fields. The
Diagnosis of ovarian teratoma
2569
Chemotherapy of teratoma with Cisplatin (1 course)
6668
Surgery treatment of ovarian teratoma
7964

University Hospital Heidelberg

9.8/10
location_onGermany, Heidelberg

Department of Obstetrics, Adult and Pediatric Gynecology

According to the Focus magazine, the University Hospital Heidelberg ranks among the top five hospitals in Germany! The hospital is one of the most advanced and reputable medical institutions not only in Germany, but throughout Europe. There are more than 43 specialized departments and 13 medical institutes, which cover all field
Diagnosis of ovarian teratoma
0
Chemotherapy of teratoma with Cisplatin (1 course)
0
Surgery treatment of ovarian teratoma
0

University Hospital Frankfurt am Main

10/10
location_onGermany, Frankfurt am Main

Department of Adult and Pediatric Gynecology, Obstetrics and Mammology

According to the reputable Focus magazine, the University Hospital Frankfurt am Main ranks among the top German medical facilities! The hospital was founded in 1914 and today is a well-known German medical facility, which combines rich traditions and scientific innovations. A medical team of more than 6,500 employees cares about
Diagnosis of ovarian teratoma
2030
Chemotherapy of teratoma with Cisplatin (1 course)
5350
Surgery treatment of ovarian teratoma
6257

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Department of Adult and Pediatric Gynecology, Mammology

According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! The hospital is one of the largest and leading university medical complexes in Europe. The hospital in Germany provides modern diagnostics and treatment of patients, a
Diagnosis of ovarian teratoma
2838
Chemotherapy of teratoma with Cisplatin (1 course)
4998
Surgery treatment of ovarian teratoma
9068

University Hospital of Ludwig Maximilian University of Munich

10/10
location_onGermany, Munich

Department of Obstetrics, Adult and Pediatric Gynecology

According to the Focus magazine, the University Hospital of Ludwig Maximilian University of Munich is regularly ranked among the best medical institutions in Germany! The hospital is the largest multidisciplinary medical facility, as well as a leading research and training center in Germany and Europe. The hospital is proud of i
Diagnosis of ovarian teratoma
2010
Chemotherapy of teratoma with Cisplatin (1 course)
5885
Surgery treatment of ovarian teratoma
6967

University Hospital Erlangen

9.1/10
location_onGermany, Erlangen

Department of Adult and Pediatric Gynecology, Mammology, Obstetrics

According to the Focus magazine, University Hospital Erlangen ranks among the best medical facilities in Germany! The hospital is one of the leading healthcare facilities in Bavaria and offers top-class medical care distinguished by the close intertwining of clinical activities with research and training of medical students. The
Diagnosis of ovarian teratoma
1891
Chemotherapy of teratoma with Cisplatin (1 course)
5588
Surgery treatment of ovarian teratoma
6600

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of Gynecology and Mammology

According to the prestigious Focus magazine, the University Hospital Halle (Saale) ranks among the top German medical facilities! The history of the hospital has more than 300 years, and during this time it managed to earn an excellent reputation not only in Germany, but throughout the world. The hospital positions itself as a s
Diagnosis of ovarian teratoma
2087
Chemotherapy of teratoma with Cisplatin (1 course)
5105
Surgery treatment of ovarian teratoma
6279

University Hospital Hamburg-Eppendorf

9.2/10
location_onGermany, Hamburg

Department of Gynecology and Mammology

According to the Focus magazine, the University Hospital Hamburg-Eppendorf ranks among the top ten hospitals in Germany! Since its foundation in 1889, the hospital has taken a leading position in the European medical arena and still occupies it until today. A highly competent medical team of more than 11,000 employees takes care
Diagnosis of ovarian teratoma
2513
Chemotherapy of teratoma with Cisplatin (1 course)
5102
Surgery treatment of ovarian teratoma
8153

University Hospital Würzburg

9.2/10
location_onGermany, Würzburg

Department of Adult and Pediatric Gynecology, Mammology and Obstetrics

According to the Focus magazine in 2019, the University Hospital Würzburg ranks among the top national German hospitals! The hospital is one of the oldest medical facilities in Germany. The centuries-old traditions of first-class treatment are combined with the very latest achievements of modern evidence-based medicine and
Diagnosis of ovarian teratoma
2081
Chemotherapy of teratoma with Cisplatin (1 course)
5112
Surgery treatment of ovarian teratoma
6293

University Hospital RWTH Aachen

8.9/10
location_onGermany, Aachen

Department of Gynecology, Mammology and Obstetrics

According to the prestigious Focus magazine, the University Hospital RWTH Aachen ranks among the top German hospitals! As a maximum care university medical facility, the hospital guarantees patients first-class medical services combined with a respectful and human attitude. The hospital integrates all the modern options for the
Diagnosis of ovarian teratoma
2101
Chemotherapy of teratoma with Cisplatin (1 course)
5881
Surgery treatment of ovarian teratoma
6838

University Hospital Duesseldorf

9.5/10
location_onGermany, Duesseldorf

Department of Adult and Pediatric Gynecology, Obstetrics and Mammology

According to the authoritative Focus magazine, the University Hospital Duesseldorf ranks among the top Germany hospitals! The hospital is an excellent example of a combination of high-quality health care, research and teaching activities. With more than 50,000 inpatients and about 300,000 outpatients every year, the hospital is
Diagnosis of ovarian teratoma
2153
Chemotherapy of teratoma with Cisplatin (1 course)
5033
Surgery treatment of ovarian teratoma
7187

University Hospital Muenster

9.8/10
location_onGermany, Muenster

Department of Adult and Pediatric Gynecology, Obstetrics

According to the Focus magazine, the University Hospital Muenster ranks among the top German hospitals! The hospital belongs to the most prestigious medical institutions in Germany. The hospital is distinguished by a high professionalism of its doctors, state-of-the-art technological equipment and the availability of the most ad
Diagnosis of ovarian teratoma
2009
Chemotherapy of teratoma with Cisplatin (1 course)
4956
Surgery treatment of ovarian teratoma
6381
| from Booking Health GmbH

Content

  1. What is an ovarian teratoma
  2. Mature teratoma
  3. Immature teratomas
  4. Symptoms
  5. Diagnosis
  6. Treatment
  7. Teratoma and fertility
  8. Prognosis
  9. Why choose hospitals abroad?
  10. Cost of treatment abroad
  11. How to start treatment abroad?

 

Teratoma is a germ cell tumor that contains different types of tissues, e.g. muscle, hair, bone, etc. Such tumors are ovarian, testicular or are located in the coccyx. What are the causes of the ovarian teratoma development and how has medicine learned to cope with it?

What is an ovarian teratomaa

 

Ovarian teratoma is an embryonic cell tumor that develops from the layers of the endo-, exo-, and mesoderm. It can be both benign and malignant. Most of such neoplasms are benign. An ovarian malignant tumor can metastasize to distant organs and body parts.

About 25-30% of all mature teratomas develop in the ovarian region, the same amount develops in the sacrum and coccyx area. Up to 10-15% of teratomas are detected in the retroperitoneal space, 5-7% – in the testicles, the same amount – in the presacral area (between the sacrum and the rectus), 5% – in the mediastinal zone (organs located between the right and left pleural cavities).

The factors contributing to the development of the ovarian tumor have not been precisely established yet. It is assumed that teratomas arise as a result of disturbances in embryogenesis, i.e. the process during which embryos are formed and developed.

Ovarian teratomas develop from the primary germ cells. During normal development, they become eggs or sperm (according to gender), but sometimes this process is interrupted, and immature cells turn into various mature tissues of the human body. The structure of mature teratomas is unpredictable. Inside mature teratomas, doctors may find skin derivatives, fragments of liver, thyroid gland, or bone tissue.

In rare cases, mature teratomas can develop in the region of the brain, on the jaws, in the nasal cavity, or lungs.

Mature teratoma

 

In the main classification, teratomas are divided into mature cystic and immature teratomas. Mature cystic teratomas have a dermoid structure. They are characterized by slow growth without affecting adjacent tissues. A mature cystic teratoma is usually a dense neoplasm covered with a fibrous capsule. Mature cystic teratoma does not tend to progress quickly and rarely transforms into a malignant tumor.

Immature teratomas

 

One of the significant problems of modern oncogynecology is ovarian tumors. Epithelial neoplasms occupy the first place in terms of frequency.

Most gynecologists and oncologists may be not familiar with rare ovarian tumors. These include immature teratomas of ovaries, which make up to 1% of all the neoplasms in the women's gonad. Mature cystic teratomas take the 3rd place in the frequency among all the germinogenic ovarian tumors. In the histological classification, immature teratomas belong to ovarian tumors of the group of cystic teratomas.

By the definition, immature teratomas contain embryonic tissues. Most often, the tissues of the nervous system at different stages of embryonic differentiation are found in immature teratomas.

Despite the absence of structures with morphological signs of malignancy, immature teratomas have the ability to invade the surrounding tissues and even metastasize. At the same time, the primary neoplasm and metastases associated with immature teratomas can exist for years without causing significant functional disorders. In those rare cases when there is the possibility of comparing the microscopic structure of the primary ovarian tumor and metastases, the convincing signs of ovarian tumor not differing much from metastatic cells with progression is observed in immature teratomas. The unexpected progression of the process with a fatal outcome can happen with immature teratomas.

A variety of clinical courses of the immature teratomas, affects the approach to the treatment of women with immature teratomas of ovaries.

Symptoms

 

The asymptomatic clinical course or mild symptoms are characteristic for mature cystic teratomas. Being mostly benign, mature cystic teratomas often become an accidental finding during clinical examination for other reasons. With large ovarian teratomas, symptoms including difficulty urinating and defecation are possible. In women with asthenic physique, an increase in the size of the abdomen is sometimes noted. The menstrual cycle is not disturbed.

Sometimes ovarian teratomas can be first detected after pregnancy. This may be due to the acceleration of the growth of the neoplasm against the background of a change in hormonal levels, increased pressure of the tumor on the uterus and pelvic organs, or torsion of the ovarian with mature cystic teratoma. Torsion of the ovarian with the mature cystic teratomas is accompanied by intense pain. It is a medical emergency requiring immediate surgery.

With immature teratomas, weakness, fatigue, and pain in the lower abdomen are observed. With the progression of the ovarian teratoma moderate normochromic anemia, weight loss, pallor, and dry skin are noted. An increase in the size of an ovarian teratoma and the involvement of nearby organs cause symptoms including a change in the pain type, impaired defecation, and urination.

In the absence of timely treatment, necrosis of the ovarian mature cystic teratoma wall is possible. It may be followed by rupture of the cyst and the development of peritonitis. Both pregnant and non-pregnant women with ovarian teratomas can feel an inflammatory process, manifested by severe pain, severe weakness, and an increase in body temperature.

Diagnosis

 

Since teratoma is a congenital condition, it is possible to diagnose it at the early stages during an ultrasound scan. But not all types of tumors can be detected in this way since some of them develop during the first few years of life. For clinical diagnostics at an older age, doctors carry out:

  • Blood tests
  • X-ray and CT scan
  • Gynecological examination
  • Endoscopic examination
  • MRI
  • Biopsy

Additionally, you may need to visit an oncologist who will determine whether the tumor is benign or not. Only after receiving all the results of clinical examinations and visiting related specialists, the doctor prescribes the most effective treatment.

Treatment

 

Treatment of ovarian teratoma of any form is operative. In torsion of the ovarian with the cystic teratomas, the surgery is performed on an emergency basis.

According to the research, removal of the primary ovarian tumor is important in treatment. At advanced stages of the disease, maximum possible cytoreduction is optimal.

The volume of surgery is determined with consideration to the size of the tumor, the age of the patient, the location of the ovarian teratoma, and the presence of concomitant diseases. In girls and young women, the removal of ovarian teratoma with affection of the pelvic organs is carried out in the form of partial resection of the ovaries. To women during menopause, complete removal of the uterus with both appendages is indicated.

Currently, surgery is carried out with the help of the laparoscopic method. Most researchers point out the need to perform the surgery without damaging the ovarian tumor capsule, not allowing the contents of the cyst to go into the abdominal cavity. However, it is not always possible to follow these requirements when performing laparoscopic surgery.

Mature cystic teratomas are usually removed laparoscopically. They have a favorable prognosis with the preservation of fertility. During surgery, a part of the ovary can be resected.

Due to the tendency to transform into a malignant form and metastasize to the lymph nodes, the treatment of cystic teratomas consists not only from surgery but also from the use of radiation therapy simultaneously with the administration of anticancer drugs.

In most cases, the prognosis is favorable. To a large extent, it depends on where the ovarian tumor was formed, as well as on how timely and sufficient the treatment was. Treatment of mature cystic teratoma, the course of which is complicated by malignant transformation, is less successful. In such cases, even the surgery does not guarantee a complete recovery.

Teratoma and fertility

 

In most cases, the tumor grows asymptomatically. In this regard, mature cystic teratomas complicate pregnancy, threatening not only the health and fertility of a woman but also the life of a child.

The type of cellular changes determines what the teratoma itself will be, namely mature cystic or immature. Mature cystic teratomas develop from embryonic tissues; these can be cells of nerves, fat, bones, muscles, etc. In the presence of unidentified cells, we are talking about immature teratomas, prone to malignancy.

Prognosis

 

The prognosis is determined by the type of the histological structure (mature cystic or immature), the primary localization of the tumor, and timely and sufficient treatment. However, women with mature cystic teratomas, as a rule, require shorter follow-up after the completion of the main therapeutic course.

Why choose hospitals abroad?

 

After the diagnosis has been made, and you have learned what teratoma is and how dangerous it is, it is better not to waste time. The earlier the treatment is started, the more favorable the prognosis is.

Now it’s a question of choosing the best hospital for treatment. You can always choose what local hospitals have to offer, but if you’re considering the option of treatment abroad, it’s reasonable to say that you’re thinking in the right direction.

Foreign hospitals have everything necessary for the effective treatment of cancer, i.e. innovative technology, medications, and techniques that are developed in world medicine are quickly introduced into the practice of foreign hospitals.

Specialists that work in foreign hospitals are considered the best in the world due to their training and qualifications. That is why oncology treatment in foreign hospitals demonstrates the highest world rates.

During treatment in foreign hospitals, several methods are usually used that complement each other and target the tumor with the help of different mechanisms of action. There is no standard scheme of cancer treatment. Depending on the results of the examination, age and the general health, each patient receives an individual treatment program while undergoing treatment in foreign hospitals.

Doctors working at foreign hospitals give preference to minimally invasive methods. This is especially important in the treatment of ovarian teratoma since the vital structures of the female reproductive system remain intact.

The precise information about the hospitals that offer the treatment of ovarian teratoma is to be found on the Booking Health website.

Cost of treatment abroad

 

Before mentioning the prices, you need to know that the figures you usually find on the web are very approximate. On the contrary, Booking Health offers treatment programs with the cost of treatment guarantee, so you’re able to know how to evaluate your financial capacity.

The cost of treatment abroad with surgery starts at 2,130 EUR.

The cost of treatment abroad with chemotherapy starts at 1,611 EUR.

The minimal price of diagnostics is 584,00 EUR.

If you want to get a consultation about the therapeutic methods and prices for treatment, leave a request on the Booking Health website.

How to start treatment abroad?

 

Well, for starters, you need to decide whether you want to arrange the treatment abroad by yourself or to use the services of a medical tourism agency.

If the latter seems more convenient to you, you’re not wrong. Treatment abroad with Booking Health implies comfort at every step of the journey. Booking Health provides the services of negotiation with hospitals, visa support, translation and interpretation, booking accommodation and so much more.

All you need to do is leave the request on the Booking Health website, and a medical advisor will contact you.

Authors: Dr. Vadim ZhiliukDr. Sergey Pashchenko




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