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Colon Cancer — CRS and HIPEC - Hyperthermic Intraperitoneal Chemoperfusion: treatment in the Best Hospitals of Germany

University Hospital of Ludwig Maximilian University of Munich

10/10
location_onGermany, Munich

Department of General, Abdominal and Transplant Surgery

According to the Focus magazine, the Department of General, Abdominal and Transplant Surgery ranks among the best departments in Germany specializing in bowel cancer treatment! The department covers the full range of services in these medical fields and holds the leading position at the national and international level in terms of the number of surgical interventions performed and their success rate. Of particular interest are operations to treat cancer, organ transplants, as well as minimally invasive surgery.

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Department of General, Abdominal and Vascular Surgery

According to the Focus magazine, the Department of General, Abdominal and Vascular Surgery ranks among the top German medical facilities specializing in the treatment of bowel and lung cancer! The department offers all the modern surgical options for the treatment of diseases of the abdominal cavity and blood vessels. The department's doctors have expert knowledge and vast experience in the treatment of colorectal cancer, stomach, esophageal, pancreatic cancers, liver metastases, inflammatory bowel diseases (diverticular disease, Crohn's disease, ulcerative colitis). Also, they specialize in the surgical treatment of vascular pathologies and thyroid diseases.

University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of General and Abdominal Surgery

The Department of General and Abdominal Surgery offers the full range of surgical treatment of diseases of the esophagus and abdominal organs, thyroid and parathyroid glands, as well as the interventions in bariatric surgery. The surgeons of the department have a deep knowledge in all open and minimally invasive surgical techniques, perform extensive operations of high complexity with maximum safety for the patient.

University Hospital Carl Gustav Carus Dresden

9.1/10
location_onGermany, Dresden

Department of Abdominal, Thoracic and Vascular Surgery

According to the Focus magazine, the Department of Abdominal, Thoracic and Vascular Surgery is included in the ranking of the top German departments specializing in colon cancer treatment! The department offers the full range of services in these medical fields. It provides the surgical treatment of diseases of the gastrointestinal tract, thyroid and parathyroid glands, thoracic organs and blood vessels. Special focus is on the treatment of gastrointestinal cancer. With appropriate clinical indications, preference is always given to minimally invasive surgical techniques.

University Hospital Frankfurt am Main

10/10
location_onGermany, Frankfurt am Main

Department of General and Abdominal Surgery

According to the Focus magazine, the Department of General and Abdominal Surgery ranks among the top German departments specializing in bowel cancer treatment! The department offers the full range of classical and minimally invasive methods for the treatment of common surgical diseases, cancer pathologies, diseases of the endocrine organs, proctological problems. The specialization also covers transplant surgery (liver, kidney and pancreas transplantation). The department is certified by the German Cancer Society for its outstanding results in the treatment of bowel, pancreatic, stomach and liver cancers.

University Hospital RWTH Aachen

9.2/10
location_onGermany, Aachen

Department of Adult and Pediatric General, Abdominal, Transplant Surgery

According to Focus magazine, the Department of Adult and Pediatric General, Abdominal, Transplant Surgery ranks among the top German medical facilities specializing in bowel cancer treatment! The department performs surgical treatment of general surgical diseases, abdominal pathologies, and also specializes in organ transplantation. Of particular interest are surgical oncology of the abdominal organs, as well as pancreatic and liver surgery. The department annually performs more than 3,000 surgical interventions, which contributes to its credibility at the national level.

University Hospital Marburg UKGM

8.6/10
location_onGermany, Marburg

Department of Abdominal, Thoracic and Vascular Surgery

The Department of Abdominal, Thoracic and Vascular Surgery offers all modern surgical interventions in these fields. Specialization covers the treatment of diseases of the abdominal organs, endocrine glands, pathologies of the lungs and chest wall, pathological vascular lesions of all parts of the body. In addition, kidney transplantation and pancreas transplantation are part of the surgeons' tasks. Whenever possible, operations are performed using minimally invasive techniques that have several advantages over classical interventions.

University Hospital Jena

8.9/10
location_onGermany, Jena

Department of General, Abdominal and Vascular Surgery

According to the Focus magazine, the Department of General, Abdominal and Vascular Surgery ranks among the top German medical facilities specializing in the treatment of bowel cancer! The department offers the full range of surgical treatment of diseases of the abdominal organs and blood vessels, including the transplantation of abdominal organs. The sparing minimally invasive surgical techniques are widely used in the clinical practice, which allow to provide treatment in simple and complex clinical cases by making small incisions and using special tiny surgical instruments. The exceptional experience and profound knowledge of the department's doctors are also an integral part of the high treatment success rates.

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of General, Abdominal, Vascular and Endocrine Surgery

The Department of General, Abdominal, Vascular and Endocrine Surgery offers the full range of medical services in these fields. The department specializes in the surgical treatment of gastrointestinal cancers (surgical treatment of pancreatic, liver, stomach, esophageal and colon malignancies), hernia repair, treatment of gastrointestinal inflammatory diseases, endocrine surgery and surgical correction of vascular diseases and defects. The treatment of patients is carried out in close cooperation with the experts from related fields, particularly, with oncologists, gastroenterologists, radiologists, angiologists, etc.

University Hospital Heidelberg

9.8/10
location_onGermany, Heidelberg

Department of General, Abdominal and Transplant Surgery

According to the Focus magazine, the Department of General, Abdominal and Transplant Surgery ranks among the top German departments specializing in bowel cancer treatment! The department offers the full range of services in these medical fields and guarantees the first-class medical care at the university level. The department specializes in the treatment of diseases of the abdominal cavity, esophagus and thyroid gland, transplantation of liver, kidney and pancreas. The medical facility has won the reputation of one of the three largest and most successful Transplant Centers in Germany. Also, within the clinical practice, doctors hold highly-specialized consultations on rare diseases and provide 24-hour emergency care. 

University Hospital Hamburg-Eppendorf

9.2/10
location_onGermany, Hamburg

Department of General, Abdominal and Thoracic Surgery

According to the Focus magazine, the Department of General, Abdominal and Thoracic Surgery ranks among the top German departments specializing in bowel cancer treatment! The department offers the full range of surgical treatment of diseases of the thorax and abdomen, endocrine glands, blood vessels and morbid obesity. If possible, the preference is always given to sparing minimally invasive surgical techniques. The department performs more than 3,000 outpatient and about 2,600 inpatient interventions every year. The department has one of the largest interdisciplinary Obesity Centers, as well as one of three supraregional Centers for Pancreatic, Stomach and Esophageal Surgery.

University Hospital Würzburg

9.2/10
location_onGermany, Würzburg

Department of General, Abdominal, Transplant, Vascular and Pediatric Surgery

The Department of General, Abdominal, Transplant, Vascular and Pediatric Surgery covers the whole range of services in these fields. The department specializes in the treatment of diseases of the upper and lower gastrointestinal tract, liver, gallbladder, pancreas, thyroid and parathyroid glands, adrenal glands, as well as overweight. In addition, the department is a recognized Center for Vascular and Pediatric Surgery.

University Hospital Tuebingen

9.2/10
location_onGermany, Tuebingen

Department of General, Abdominal, Adult and Pediatric Transplant Surgery

According to the Focus magazine, the Department of General, Abdominal, Adult and Pediatric Transplant Surgery ranks among the top German departments specializing in the treatment of bowel cancer! The department specializes in the treatment of tumors of the gastrointestinal tract, pancreas, liver, and retroperitoneal space (peritoneal carcinomatosis), liver, kidney, pancreas, bowel transplantations in children and adults, as well as the surgical treatment of obesity and general surgical interventions.

University Hospital Rechts der Isar Munich

9.8/10
location_onGermany, Munich

Department of Surgery

The Department of Surgery offers the full range of services in this field and specializes in general, abdominal, thoracic, transplant surgery. The medical team of the department, consisting of 10 specialized senior physicians, 30 medical specialists and assistant physicians, as well as highly motivated nursing staff, provides first-class treatment of tumors, inflammatory and degenerative diseases of the esophagus, stomach, intestines, pancreas, liver, gallbladder, spleen, lungs, thyroid and parathyroid glands. The department is headed by Prof. Dr. med. Helmut Friess.

University Hospital Muenster

9.8/10
location_onGermany, Muenster

Department of General, Abdominal and Transplant Surgery

According to the Focus magazine, the Department of General, Abdominal and Transplant Surgery is ranked among the top German medical facilities specializing in the bowel cancer treatment! The department offers the full range of services in these medical fields. The main clinical focuses include the surgical treatment of abdominal oncopathology, robotic surgery, minimally invasive surgery, endoscopy, organ transplantation and intensive care after surgical treatment. The department's doctors have special competence in the treatment of intestinal, pancreatic, stomach and liver cancers (certification of the German Cancer Society).

University Hospital Duesseldorf

9.5/10
location_onGermany, Duesseldorf

Department of General, Abdominal and Pediatric Surgery

The Department of General, Abdominal and Pediatric Surgery offers the full range of surgical treatment of diseases of the organs of abdominal cavity, thorax, emergency surgical care in polytrauma, as well as many surgical interventions in children. Of particular interest is cancer surgery on the liver, gallbladder, and pancreas. In addition, the department's specialists masterfully manage all the methods of bariatric surgery. Many operations are performed using minimally invasive techniques, which facilitate the quickest possible recovery of the patient.

Colon cancer therapy in Germany is carried out using advanced methods, one of which is the hyperthermic intraperitoneal chemotherapy method (HIPEC). This chemotherapy technique helps in the treatment of malignant neoplasms that have spread from the internal organs to the inner space of the abdominal cavity.

Colon cancer overview

Colon cancer is the formation of malignant cells in the lining of the intestinal wall. Colon cancer usually develops from a benign or borderline polyp.

The development of the colon cancer process is not rapid. According to clinical data, it takes cancer cells from 1,5 to 2 years to invade all layers of the intestinal wall. Then the malignant process may affect the pelvic bones, other inner organs and tissues located nearby. Through the lymphatic system, cancer cells can spread throughout the body, forming separate foci of cancer called metastases. They are most often found in the regional lymph nodes, lungs, or liver.

Treatment with HIPEC therapy

Some cancers are very difficult to treat and some of them, until recently, were considered incurable. Tumors that have spread to the abdomen are classified as peritoneal malignancies.

The abdominal cavity is the space in the abdomen that includes the stomach, colon, liver, uterus, ovaries, and other abdominal organs. Cancer cells that are located inside the abdominal organs can spread to the abdominal cavity. This is called peritoneal carcinomatosis or peritoneal metastases and is traditionally considered incurable. Most metastases originate from the abdominal organs, including metastases from colon cancer, appendix cancer, ovarian cancer, pancreatic cancer, and stomach cancer. Although primary cancers of the peritoneum are rare, they include primary peritoneal carcinoma.

The development of cancer therapy techniques has made it possible to improve the primary therapy of peritoneal metastases. Modern cancer treatment has moved on from the old regimens of palliative therapy with chemotherapy or palliative surgery aimed at relieving symptoms to a new era of radical surgery in combination with heated chemotherapy (HIPEC), providing patients with new hope for treatment.

A new approach in therapy of cancer that had spread to the peritoneum combines surgery and chemotherapy during surgery. This treatment approach is the result of long and extensive research showing that some chemotherapy drugs can effectively affect malignant tissues when injected directly into the abdominal cavity.

Some of the chemotherapeutic drugs can kill cancer cells more effectively when heated. There have been many studies on the effects of heat (hyperthermia) on cancer cells. It has shown that heat can stop the growth of cancer cells. The researchers found that therapy using heated to the 42-44 degrees Celsius drugs kill cancer cells with little damage to healthy tissues.

A number of studies in the United States and Europe have shown that colon cancer patients receiving HIPEC therapy increased their life expectancy by more than five years.

In regard to hyperthermic intraperitoneal chemotherapy (HIPEC), the term "intraperitoneal" means that the chemotherapy drugs are delivered directly to the abdominal cavity. The term "hyperthermic" means that the solution is heated to a temperature higher than normal body temperature. Since heated chemotherapy can only penetrate a very limited area of the tumor tissue, it is necessary to remove all visible tumor formations before starting HIPEC.

The HIPEC therapy involves direct contact between malignant cells on the walls of the peritoneum and hot solutions of chemotherapy drugs. Therefore, HIPEC therapy is a two-step process. First, the surgeon removes as much tumor tissue as possible, not including distant metastasis. This intervention is called cytoreductive surgery (CRS) and is aimed at reducing the number of malignant cells. As a result, the cancer intoxication decreases, and the patient's condition improves. The remaining tumor lesions are treated with a chemotherapy drug that is heated up to about 41-42 degrees Celsius.

Tumor cells are more sensitive to heat than healthy cells. Therefore, hyperthermic chemotherapy affects them more. Direct contact between the tumor and the highly concentrated drug solution increases the rate of the drug absorption and the overall efficacy of HIPEC therapy compared to standard intravenous administration of drugs.

In most cases, HIPEC therapy uses a reservoir with a pump, in which the drug solution is heated. The solution is delivered through a drainage tube into the abdominal cavity. The abdominal cavity is open during the HIPEC session, and liquid is removed through a drainage tube introduced from the opposite side.

Surgery to remove colon tumors is lengthy, complex, and includes hot chemotherapy for 90 minutes. Therefore, it is important to make sure that candidates for this type of surgery are eligible for the procedure. For this treatment, only patients who do not have serious heart or pulmonary diseases are eligible.

Where can I undergo CRS and HIPEC treatment in Germany?

Health tourism is becoming more and more popular these days, as medicine in Germany often ensures a much better quality of colon cancer treatment with HIPEC.

The following hospitals show the best success rates in colon cancer treatment with CRS and HIPEC:

  1. University Hospital of Ludwig Maximilian University of Munich
  2. Charite University Hospital Berlin
  3. University Hospital Ulm
  4. University Hospital Carl Gustav Carus Dresden
  5. University Hospital Frankfurt am Main

You can find more information about the hospitals in Germany on the Booking Health website.

The cost of treatment in Germany

The prices in hospitals listed on the Booking Health website are relatively low. With Booking Health, you can undergo colon cancer treatment with CRS and HIPEC in Germany at an affordable price.

The cost of treatment varies, as the price depends on the hospital, specifics of the disease, and the complexity of its treatment.

The cost of treatment with HIPEC and CRS in Germany is 38,154-67,436 EUR.

You also need to consider the cost of possible additional procedures and follow-up care. Therefore, the ultimate cost of treatment in Germany may differ from the initial price.

To make sure that the overall cost of treatment in Germany is suitable for you, contact us by leaving the request on the Booking Health website.

How can I undergo CRS and HIPEC treatment in Germany?

It is not easy to self-organize any treatment abroad. It requires certain knowledge and expertise. Thus, it is safer, easier, and less stressful to shift some responsibility onto a medical tourism agency.

As the largest and most transparent medical tourism agency in the world, Booking Health has up-to-date information about colon cancer treatment with CRS and HIPEC in the best hospitals in Germany. Therefore, we will help you select the right clinic taking into account your wishes for treatment.

We want to help you and take on all the troubles. You can be free of unnecessary stress, while Booking Health takes care of all organizational issues regarding the treatment. Our services are aimed at undergoing colon cancer treatment in Germany with CRS and HIPEC safely and successfully.

Medical tourism can be easy! All you need to do is to leave a request on the Booking Health website, and our manager will contact you shortly.




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