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Acute Lymphoblastic Leukemia (all) — High-intensity Induction Chemotherapy 2 Blocks): treatment in the Best Hospitals in the World

University Hospital Mannheim

9.8/10
location_onGermany, Mannheim

Department of Hematology and Oncology

The Department of Hematology and Oncology offers the full range of services in these medical fields. It diagnoses and treats all benign and malignant blood diseases, cancers. The huge clinical experience and high competence of the doctors working in the department allow them to achieve excellent treatment results even in the most severe cases.

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University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of Hematology, Oncology, Palliative Care, Rheumatology and Infectology

The Department of Hematology, Oncology, Palliative Care, Rheumatology and Infectology offers the full range of services in these fields. It provides the accurate diagnostics and effective treatment of oncological diseases, benign and malignant blood pathologies, rheumatic and infectious diseases. A separate focus of the department is palliative care aimed at relieving pain and improving the quality of life of the terminally ill patients. The doctors of the department have unique clinical skills and rich experience, which contributes to high treatment success rates.

Medicana International Ankara Hospital

9/10
location_onTurkey, Ankara

Department of Hematology and Bone Marrow Transplantation

The Department of Hematology and Bone Marrow Transplantation at the Medicana International Ankara Hospital is a leading private medical center in Ankara offering services of bone marrow transplantation. In the nine-bed Department, various kinds of bone marrow transplantation are performed to treat a wide range of both oncohematological and other diseases. Since December 2012, the Department is licensed by the Ministry of Health in Turkey.

Samsung Medical Center Seoul

9.8/10
location_onSouth Korea, Seoul

Department of Oncology and Hematology

The Department of Oncology and Hematology offers the full range of services in these medical fields. The main clinical focuses include diagnostics and treatment of various forms of oncological diseases and blood diseases. The medical team of the department strives not only to prolong the life of patients, but also to improve its quality.

 

Tel Aviv Sourasky Medical Center

9.9/10
location_onIsrael, Tel Aviv

Department of Hematology

The Department of Hematology provides highly qualified care to patients suffering from various blood diseases, including malignant hematological diseases. The treatment of malignant diseases of the hematopoietic system is based on the use of various schemes of intensive chemotherapy and bone marrow transplantation. If desired, the patients can be treated within the clinical trials. As a rule, this option is offered to the patients who do not have positive dynamics due to the application of classical treatment methods.

University Hospital Freiburg

9.7/10
location_onGermany, Freibung

Department of Hematology and Oncology

The Department of Hematology and Oncology offers the full range of diagnostics and treatment of blood diseases, coagulation disorders, oncological diseases and related pathological conditions. The treatment is provided both on an outpatient and inpatient basis. The patient is offered a comprehensive treatment, including intensive care to eliminate side effects associated with the tumor and therapy, development of individual recommendations on nutrition, physiotherapeutic measures and psycho-oncological care.

University Hospital Heidelberg

9.8/10
location_onGermany, Heidelberg

Department of Hematology, Oncology, Adult and Pediatric Rheumatology

The Department of Hematology, Oncology, Adult and Pediatric Rheumatology offers the full range of modern diagnostics and treatment of malignant diseases, rheumatic pathologies, including particularly complex clinical cases in these fields. In addition, the department's doctors specialize in stem cell transplantation and occupy leading positions in this field at the international level. The medical team of the department makes every effort to guarantee each patient an individual, first-class treatment, based on the very latest achievements of modern medicine and human respect, understanding of the needs of each patient.

University Hospital Frankfurt am Main

10/10
location_onGermany, Frankfurt am Main

Department of Hematology, Oncology, Hemostaseology, Rheumatology and Infectology

The Department of Hematology, Oncology, Hemostaseology, Rheumatology and Infectology offers the full range of medical services in the fields of its specialization. The department specializes in the diagnostics and treatment of all diseases of the hematopoietic system, systemic treatment of solid tumors, infectious diseases, including outpatient admission of patients with HIV, blood clotting disorders, as well as the entire clinical and morphological group of rheumatic diseases. The department is actively engaged in research activities and regularly implements the latest medical developments into clinical practice, thereby providing treatment in accordance with the most advanced scientific achievements.

University Hospital Würzburg

9.2/10
location_onGermany, Würzburg

Department of Gastroenterology, Hematology, Oncology, Hepatology, Infectology, Rheumatology and Clinical Immunology

The Department of Gastroenterology, Hematology, Oncology, Hepatology, Infectology, Rheumatology and Clinical Immunology offers the full range of diagnostics and treatment in these fields. The department specializes in the treatment of benign and malignant diseases of the digestive system, liver and bile ducts, the hematopoietic system, etc. Much attention is paid to the interdisciplinary cooperation (Cancer Center Mainfranken, etc.).

University Hospital RWTH Aachen

8.7/10
location_onGermany, Aachen

Department of Oncology and Hematology

The Department of Oncology and Hematology offers accurate diagnostics and effective treatment of benign and malignant blood diseases, as well as solid tumors. The department's specialists are proud of the excellent results in the field of bone marrow transplantation, which is among the department’s priority focuses. The department has 61 beds. Medical care is carried out both on an outpatient and inpatient basis.

University Hospital Erlangen

9.1/10
location_onGermany, Erlangen

Department of Hematology and Oncology

The Department of Hematology and Oncology offers the full range of diagnostics and treatment of diseases of the hematopoietic system, such as acute or chronic leukemia, malignant lymphomas, as well as solid malignant tumors, which require chemotherapy or other systemic therapies. The department offers all systemic treatments, including bone marrow transplantation, antibody therapy. The main goal of each medical team employee is to provide patients with a competent medical care.

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of Hematology and Oncology

According to the Focus magazine, the Department of Hematology and Oncology ranks among the top German medical facilities specializing in bowel cancer treatment! The department offers the full range of specialized diagnostics, treatment and follow-up care for patients with oncological diseases and blood diseases. The department's doctors have in their arsenal many innovative effective methods to fight against cancer. In addition, a number of clinical trials are carried out here in order to develop the very latest targeted drugs, immunotherapy drugs, etc. All the department's specialists regularly undergo advanced training courses, which help them to keep abreast of innovations in medicine and to guarantee the best therapy result for patients.

University Hospital Hamburg-Eppendorf

9.2/10
location_onGermany, Hamburg

Department of Hematology, Oncology and Pulmonology

According to the Focus magazine, the Department of Hematology, Oncology and Pulmonology ranks among the top medical facilities in Germany specializing in bowel cancer treatment! The department offers the full range of modern diagnostics and treatment of solid tumors, benign and malignant blood and hematopoietic system diseases, including bleeding disorders, as well as pathologies of the lungs and other organs of the respiratory system. The offer is complemented by effective palliative care. All physicians of the department are highly qualified experts in their area of specialization and apply theoretical knowledge and clinical experience to ensure an optimal therapy result.

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Charité Comprehensive Cancer Center

Charité Comprehensive Cancer Center offers patients the full range of classical and innovative examinations, treatment of malignant diseases of all organs and anatomical structures of the human body. The spectrum is complemented by follow-up medical care, rehabilitation, modern schemes for the prevention and early detection of malignant diseases. An important component of the therapeutic process in the center is psycho-oncological care. The centerdals with the treatment of patients of all age groups, ranging from small children to elderly patients.

University Hospital Bonn

9.2/10
location_onGermany, Bonn

Department of Oncology, Hematology, Rheumatology and Immunoncology

The Department of Oncology, Hematology, Rheumatology and Immunoncology offers the full range of diagnostics and treatment of solid tumors, benign and malignant diseases of blood and bone marrow, rheumatic pathologies. The priority purpose of each employee in the department is to provide patients with an optimal medical care, based on the use of the very latest treatment methods. The department's specialists are distinguished by their high professionalism and colossal experience in the treatment of extremely complex clinical cases.

University Hospital of Ludwig Maximilian University of Munich

10/10
location_onGermany, Munich

Department of Oncology and Hematology

The Department of Oncology and Hematology offers the full range of services in the field of diagnostics and treatment of oncological and blood diseases. Of particular interest is the treatment of patients with acute leukemia, lymphomas, carcinomas and sarcomas. The highly qualified medical team of 65 doctors and 130 nurses takes care of the health of the patients. About 2,800 inpatients and 10,000 outpatients are treated in the department annually.

Acute lymphoblastic leukemia is one of the most dangerous oncohematological diseases. In a natural course, it leads to the death of a patient within a few months, but with the help of chemotherapy, it is possible to significantly increase life expectancy, and sometimes completely cure the disease. The best treatment successes can be achieved in children, while in adults relapses occur much more often.

What is induction chemotherapy?

The main treatment option in acute lymphoblastic leukemia is chemotherapy. It is performed in several stages:

  1. Induction.
  2. Consolidation.
  3. Supportive care.

After the diagnostics of the disease, the treatment begins with induction. It suggests an intensive course of chemotherapy. 3 drugs are administered simultaneously. If the patient is assigned to a high-risk group, the fourth drug will be added.

The purpose of induction is to achieve a state of complete remission. A remission is a reduction in the levels of blast cells in the red bone marrow up to 5% or less. In response to chemotherapy, a prognosis of the disease outcome can be made and further treatment tactics can be determined.

The induction period has a short duration, usually several weeks. In subsequent stages, chemotherapy becomes less intense, but longer. It is required for relapse prevention.

Side effects

A child may experience side effects. Their cause is that induction chemotherapy is highly intense. According to modern protocols, the patient receives 3, and sometimes 4, high-dose drugs.

Common symptom caused by induction:

  • weakness;
  • hair loss;
  • bowel disorders;
  • decreased appetite;
  • nausea.

Other symptoms appear due to the decreased number of blood cells. This inevitably occurs, since chemotherapy blocks primarily cell division, which divide quickly and often. Not only the tumor suffers, but also the healthy cells of the child's body, especially the bone marrow. Such treatment has the following side effects:

  • bruises on the body, nosebleeds due to the decreased number of platelets;
  • increased risk of infections – a consequence of a reduced production of leukocytes;
  • skin paleness, tachycardia, shortness of breath – symptoms caused by the reduced production of erythrocytes.

The number of cells in the blood remains low during the entire period of induction, as well as during a few weeks after the therapy completion. It increases gradually. The protocols for provision of medical care to children abroad allow for the elimination of these complications by means of transfusion of blood and its components. The feedback from patients and their parents suggests that this procedure helps to overcome most of the unpleasant and dangerous symptoms.

Due to weak immunity, some patients have infectious complications. According to the protocol, the antibiotics can be prescribed in the case of bacterial complications. Additional surgery may be occasionally required for dissection of the abscesses.

Some drugs have the following side effects:

  • dry eye syndrome;
  • impaired coordination;
  • tingling in legs and arms.

A rare complication is the formation of another cancer. It can be acute myeloid leukemia or non-Hodgkin lymphoma.

Tumor lysis syndrome is rare in oncology, as it is observed only in patients who receive a course of induction therapy at the advanced stage of the disease. Once cancer cells die, their contents will enter the bloodstream and overload the excretory system. The kidneys are most affected. Sometimes electrolyte disturbances can occur, which negatively affects the condition of the heart and nervous system. Nonetheless, good clinics abroad constantly examine the patient. In the case of diagnostics of complications resulting from the destruction of the tumor, the protocols suggest supportive medical care.

Treatment results

Pediatric oncology has achieved great success in the treatment of acute lymphoblastic leukemia. In addition, young age is a prognostically favorable factor in B-cell leukemia. The disease is much more severe in adults, while relapses occur more often.

The remission in the treatment of a child is achieved in 95% of cases within one month after the completion of the induction phase. The tests show that the number of blast cells in the red bone marrow is reduced up to 5% or less. This is an indicator of the norm, because such a number of cells are contained in the bone marrow of a healthy person.

In the future, the risk of relapse depends on many factors,. These are:

  • levels of blast cells in the blood at the beginning of treatment;
  • type of leukemia – relapses are much less common in B-cell leukemia in children under 9 years old;
  • genetic changes in tumor cells;
  • response to treatment – the risk of relapse is lower if the patient responds well to chemotherapy within 1-2 weeks after its initiation.

Treatment abroad with the Booking Health company

To receive the high-quality treatment of acute lymphoblastic leukemia in children at an affordable price, please contact the Booking Health company. You will be treated by the best specialists in the world according to modern healthcare protocols. We provide the following services and benefits:

  • Selection of the best clinic, which specializes in the treatment of acute lymphoblastic leukemia in children and achieves the best results in this field of oncology.
  • Reduced cost of medical services due to the lack of coefficients and overpricing for foreign patients.
  • Booking an appointment on the most suitable dates for you.
  • Preparation of the program taking into account previously performed diagnostics.
  • Establishment of communication directly with your attending physician.
  • Monitoring of the program at all its stages.
  • Control of the costs of procedures and operations, return of unspent funds.
  • Buying and forwarding of medicines.
  • Organization of additional diagnostics, conservative treatment, surgery or rehabilitation.
  • Communication with the clinic upon completion of surgery or chemotherapeutic treatment of acute lymphoblastic leukemia.

People leave good reviews about our work. The Booking Health company will fully arrange your medical treatment abroad, help you to prepare the documents, translate your medical history, book a hotel and airline tickets. We will meet you at the airport, take you to the clinic and provide interpreting services. We offer top-class services at affordable price, so you will receive high-quality medical care and save a lot of money.




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