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Acute Lymphoblastic Leukemia (all) — High-intensity Induction Chemotherapy 2 Blocks): treatment in the Best Hospitals of Germany

University Hospital Mannheim

9.8/10
location_onGermany, Mannheim

Department of Hematology and Oncology

The Department of Hematology and Oncology offers the full range of services in these medical fields. It diagnoses and treats all benign and malignant blood diseases, cancers. The huge clinical experience and high competence of the doctors working in the department allow them to achieve excellent treatment results even in the most severe cases.

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University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of Hematology, Oncology, Palliative Care, Rheumatology and Infectology

The Department of Hematology, Oncology, Palliative Care, Rheumatology and Infectology offers the full range of services in these fields. It provides the accurate diagnostics and effective treatment of oncological diseases, benign and malignant blood pathologies, rheumatic and infectious diseases. A separate focus of the department is palliative care aimed at relieving pain and improving the quality of life of the terminally ill patients. The doctors of the department have unique clinical skills and rich experience, which contributes to high treatment success rates.

University Hospital Freiburg

9.7/10
location_onGermany, Freibung

Department of Hematology and Oncology

The Department of Hematology and Oncology offers the full range of diagnostics and treatment of blood diseases, coagulation disorders, oncological diseases and related pathological conditions. The treatment is provided both on an outpatient and inpatient basis. The patient is offered a comprehensive treatment, including intensive care to eliminate side effects associated with the tumor and therapy, development of individual recommendations on nutrition, physiotherapeutic measures and psycho-oncological care.

University Hospital Heidelberg

9.8/10
location_onGermany, Heidelberg

Department of Hematology, Oncology, Adult and Pediatric Rheumatology

The Department of Hematology, Oncology, Adult and Pediatric Rheumatology offers the full range of modern diagnostics and treatment of malignant diseases, rheumatic pathologies, including particularly complex clinical cases in these fields. In addition, the department's doctors specialize in stem cell transplantation and occupy leading positions in this field at the international level. The medical team of the department makes every effort to guarantee each patient an individual, first-class treatment, based on the very latest achievements of modern medicine and human respect, understanding of the needs of each patient.

University Hospital Frankfurt am Main

10/10
location_onGermany, Frankfurt am Main

Department of Hematology, Oncology, Hemostaseology, Rheumatology and Infectology

The Department of Hematology, Oncology, Hemostaseology, Rheumatology and Infectology offers the full range of medical services in the fields of its specialization. The department specializes in the diagnostics and treatment of all diseases of the hematopoietic system, systemic treatment of solid tumors, infectious diseases, including outpatient admission of patients with HIV, blood clotting disorders, as well as the entire clinical and morphological group of rheumatic diseases. The department is actively engaged in research activities and regularly implements the latest medical developments into clinical practice, thereby providing treatment in accordance with the most advanced scientific achievements.

University Hospital RWTH Aachen

8.7/10
location_onGermany, Aachen

Department of Oncology and Hematology

The Department of Oncology and Hematology offers accurate diagnostics and effective treatment of benign and malignant blood diseases, as well as solid tumors. The department's specialists are proud of the excellent results in the field of bone marrow transplantation, which is among the department’s priority focuses. The department has 61 beds. Medical care is carried out both on an outpatient and inpatient basis.

University Hospital Würzburg

9.2/10
location_onGermany, Würzburg

Department of Gastroenterology, Hematology, Oncology, Hepatology, Infectology, Rheumatology and Clinical Immunology

The Department of Gastroenterology, Hematology, Oncology, Hepatology, Infectology, Rheumatology and Clinical Immunology offers the full range of diagnostics and treatment in these fields. The department specializes in the treatment of benign and malignant diseases of the digestive system, liver and bile ducts, the hematopoietic system, etc. Much attention is paid to the interdisciplinary cooperation (Cancer Center Mainfranken, etc.).

University Hospital Erlangen

9.1/10
location_onGermany, Erlangen

Department of Hematology and Oncology

The Department of Hematology and Oncology offers the full range of diagnostics and treatment of diseases of the hematopoietic system, such as acute or chronic leukemia, malignant lymphomas, as well as solid malignant tumors, which require chemotherapy or other systemic therapies. The department offers all systemic treatments, including bone marrow transplantation, antibody therapy. The main goal of each medical team employee is to provide patients with a competent medical care.

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of Hematology and Oncology

According to the Focus magazine, the Department of Hematology and Oncology ranks among the top German medical facilities specializing in bowel cancer treatment! The department offers the full range of specialized diagnostics, treatment and follow-up care for patients with oncological diseases and blood diseases. The department's doctors have in their arsenal many innovative effective methods to fight against cancer. In addition, a number of clinical trials are carried out here in order to develop the very latest targeted drugs, immunotherapy drugs, etc. All the department's specialists regularly undergo advanced training courses, which help them to keep abreast of innovations in medicine and to guarantee the best therapy result for patients.

University Hospital Hamburg-Eppendorf

9.2/10
location_onGermany, Hamburg

Department of Hematology, Oncology and Pulmonology

According to the Focus magazine, the Department of Hematology, Oncology and Pulmonology ranks among the top medical facilities in Germany specializing in bowel cancer treatment! The department offers the full range of modern diagnostics and treatment of solid tumors, benign and malignant blood and hematopoietic system diseases, including bleeding disorders, as well as pathologies of the lungs and other organs of the respiratory system. The offer is complemented by effective palliative care. All physicians of the department are highly qualified experts in their area of specialization and apply theoretical knowledge and clinical experience to ensure an optimal therapy result.

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Charité Comprehensive Cancer Center

Charité Comprehensive Cancer Center offers patients the full range of classical and innovative examinations, treatment of malignant diseases of all organs and anatomical structures of the human body. The spectrum is complemented by follow-up medical care, rehabilitation, modern schemes for the prevention and early detection of malignant diseases. An important component of the therapeutic process in the center is psycho-oncological care. The centerdals with the treatment of patients of all age groups, ranging from small children to elderly patients.

University Hospital Bonn

9.2/10
location_onGermany, Bonn

Department of Oncology, Hematology, Rheumatology and Immunoncology

The Department of Oncology, Hematology, Rheumatology and Immunoncology offers the full range of diagnostics and treatment of solid tumors, benign and malignant diseases of blood and bone marrow, rheumatic pathologies. The priority purpose of each employee in the department is to provide patients with an optimal medical care, based on the use of the very latest treatment methods. The department's specialists are distinguished by their high professionalism and colossal experience in the treatment of extremely complex clinical cases.

University Hospital Giessen UKGM

9.5/10
location_onGermany, Giessen

Department of Oncology, Hematology and Palliative Care

The Department of Oncology, Hematology and Palliative Care offers all the options of modern medicine for the treatment of patients with the pathologies in these fields. Specialization covers the treatment of cancer of the internal organs, blood cancer, symptomatic treatment of progressive incurable diseases. Other focuses of the department are intensive care medicine and special pain therapy. To achieve successful and long-term results, the clinical practice is based on the use of effective classic and innovative treatment methods.

University Hospital of Ludwig Maximilian University of Munich

10/10
location_onGermany, Munich

Department of Oncology and Hematology

The Department of Oncology and Hematology offers the full range of services in the field of diagnostics and treatment of oncological and blood diseases. Of particular interest is the treatment of patients with acute leukemia, lymphomas, carcinomas and sarcomas. The highly qualified medical team of 65 doctors and 130 nurses takes care of the health of the patients. About 2,800 inpatients and 10,000 outpatients are treated in the department annually.

University Hospital Muenster

9.8/10
location_onGermany, Muenster

Department of Hematology, Hemostaseology, Oncology and Pulmonology

The Department of Hematology, Hemostaseology, Oncology and Pulmonology offers the full range of diagnostics and treatment of blood diseases, including oncopathologies and blood coagulation disorders, lung diseases, and rare malignant diseases. The department incorporates two modern Bone Marrow Transplantation Centers. In addition, the department belongs to the largest medical facilities in Germany, which specialize in the treatment of malignant lymphomas, acute leukemias, sarcomas, as well as bone marrow transplantation. The physicians of the department are committed to providing patients with the comprehensive medical care of the highest quality, based on the respective attitude towards patients.

University Hospital Marburg UKGM

8.6/10
location_onGermany, Marburg

Department of Hematology, Oncology and Immunology

According to the Focus magazine, the Department of Hematology, Oncology and Immunology ranks among the top German medical facilities specializing in leukemia treatment! The department offers accurate diagnostics and effective treatment of malignant and benign blood diseases, solid tumors. The patients are treated in close collaboration with the Comprehensive Cancer Center. Of particular interest to the department's doctors is the treatment of various types of leukemia (within the specialized center with advanced infrastructure). The department takes part in many national and international clinical trials, which makes it possible for patients with advanced stages of cancer to receive treatment using innovative therapeutic methods.

Acute lymphoblastic leukemia is a dangerous hematologic disease, which is one and a half times more common in children than in adults. The peak incidence occurs at the age of 5 years. All patients receive chemotherapy. It is performed in several stages. There can also be used other treatments, such as bone marrow transplantation, irradiation of the brain or testicles.

What is induction?

The treatment of acute lymphoblastic leukemia does not involve surgery as in other types of cancer. The treatment is based on chemotherapy. The treatment involves three stages. These are:

  1. Induction.
  2. Consolidation.
  3. Maintenance therapy.

The induction phase aims to achieve remission. This is the most active treatment phase when several drugs are administered in large doses. In complete remission, a bone marrow testing shows that it contains no more than 5% of blast cells. Most patients manage to achieve remission. However, they need additional treatment to avoid a relapse.

Side effects of induction

Induction involves the administration of high doses of chemotherapy. The doctors can simultaneously apply three and sometimes four drugs (in children with prognostically unfavorable factors). Although induction is less intense in lymphoblastic leukemia than in myeloblastic leukemia, it still can cause certain side effects. Most of them are reversible. Upon therapy completion, the side effects will disappear over time.

Here are some standard symptoms, which can occur during the chemotherapy for any tumor:

  • hair loss;
  • delayed wound healing;
  • decreased appetite;
  • nausea;
  • diarrhea.

The consequence of cancer treatment is always the inhibition of red bone marrow function. The following symptoms can be caused by the decreased number of blood cells:

  • the decreased number of platelets causes blood-clotting disorder, so there may appear bruises on the skin, the slightest scratches can bleed for a long time, nosebleeds are possible, women can have long and heavy menstrual periods;
  • the decreased number of erythrocytes results in anemia, blood transports oxygen poorly, skin becomes pale, heart rate increases, weakness and shortness of breath appear;
  • the symptoms of the decreased leukocyte levels do not usually manifest themselves, but such changes in the blood can lead to the increased risk of infectious diseases.

All changes can be detected in the tests. If they occur, the patient may be prescribed maintenance therapy. The patient undergoes transfusion of blood or its components.

The following side effects are associated with the use of only a few chemotherapy options:

  • dry eyes;
  • impaired coordination;
  • numbness in the arms or legs.

Anthracycline drugs are cardiotoxic. Some drugs negatively affect kidney and liver function. To avoid complications, the doctor carefully studies patient's medical history before the selection of a tumor therapy option, and he also performs diagnostics in dynamics. The tests may reveal kidney or liver lesions, while the doctor can timely detect functional impairment of the heart muscle using ECG.

Tumor lysis syndrome is a complication, which develops at the initial stage of induction, but only when the disease is detected at the advanced stages. Should the patient have a large number of tumor cells, the load on the excretory system of the body will sharply increase in case of their decay. The symptoms of intoxication occur. This affects kidneys, and therefore, electrolyte metabolism disorders may develop. Such patients require supportive medical care.

Occasionally, intensive and prolonged chemotherapy can lead to the formation of another type of cancer. It can be myeloid leukemia or non-Hodgkin lymphoma. These neoplasms require surgical removal.

Treatment results

A child usually responds to the treatment better than an adult patient. In 95% of children, remission can be achieved within 1 month of induction chemotherapy. Many people manage to recover completely, but the duration of treatment is 2-3 years.

The relapses most often occur during maintenance therapy. They are less common within 12 months upon treatment completion. If a child does not have a relapse of the disease within 2 years upon treatment completion, he is very likely not to have it again in his life. 

The adults have worse treatment outcomes. Although 60% of patients with acute lymphoblastic leukemia are children, 8 out of 10 deaths from this disease occur in adults. The prognosis worsens with age. The worst outcomes of oncology are noted after the age of 65 years.

According to the results of induction chemotherapy, the adults can achieve remission in 85% of cases, but this may require a longer and more intensive treatment. The problem of some patients is that they cannot undergo intensive chemotherapy due to the presence of concomitant somatic diseases. Due to this, the doses of the drugs can be reduced. Such treatment does not aim to cure pathology, but can only increase life expectancy, thereby delaying the onset of relapse.

Treatment in Germany with the Booking Health company

To undergo induction chemotherapy in Germany at an affordable cost, you can use the services of the Booking Health company. We will arrange your diagnostics and treatment abroad. You can undergo cancer treatment in Germany at the best Cancer Centers. We provide the following services and benefits:

  • Selection of the best German hospital for cancer treatment. We will select the Cancer Center specializing in the diagnostics and chemotherapy of blood cancer.
  • The cost of medical services will be reduced for you. The saving on the course reaches up to 50%. The cost reduction is associated with the absence of overpricing and additional coefficients, which are provided for foreign patients at the hospitals specializing in cancer treatment.
  • Booking an appointment on the most suitable dates for you.
  • Preparation of the program, taking into account previously performed examinations.
  • Establishment of communication directly with the attending physician.
  • Monitoring of the program at all its stages.
  • Control of the cost of procedures and operations, return of unspent funds upon therapy course completion.
  • Buying and forwarding of medicines.
  • Organization of additional diagnostics, medical procedures, operations or rehabilitation.
  • Communication with the hospital upon treatment completion in Germany.

The reviews about the Booking Health company are mostly positive. The patients are satisfied with our services because we take care of all the organizational issues. We will provide translation of a medical history and other medical documentation, preparation of documents, booking of hotel and airline tickets, transfer from the airport. Surely, your feedback about the Booking Health services will also be positive after treatment completion. Thanks to our work, you can undergo the best treatment at a reduced cost.




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