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Diagnostic and treatment of Acute Lymphoblastic Leukemia

Due to the difficulties associated with the organization of treatment in Turkey, Switzerland, South Korea and India, we are not currently processing requests to these regions.

If you are interested in treatment in Germany, please leave a request and our specialists will contact you as soon as possible.

 

Cost for treatment

Acute Lymphoblastic Leukemia (ALL) Diagnosis
 from  8903
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
 from  97374
Consolidation treatment for acute lymphoblastic leukemia
 from  43984

University Hospital Mannheim

9.8/10
location_onGermany, Mannheim

Department of Hematology and Oncology

According to the reputable Focus magazine, the University Hospital Mannheim ranks among the top medical institutions of Germany, which is an undeniable confirmation of the impeccable medical care and excellent reputation of the hospital! The hospital is a high-tech modern medical institution, which provides accurate diagnosis an
Acute Lymphoblastic Leukemia (ALL) Diagnosis
14408
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
212145
Consolidation treatment for acute lymphoblastic leukemia
72809

University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of Hematology, Oncology, Palliative Care, Rheumatology and Infectology

The University Hospital Ulm started its activities 35 years ago and during this time it has become one of the most prestigious medical institutions in Europe. The hospital is famous for its numerous discoveries and the world-class achievements in medicine and pharmaceuticals. The medical facility has 29 specialized departments a
Acute Lymphoblastic Leukemia (ALL) Diagnosis
16610
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
271200
Consolidation treatment for acute lymphoblastic leukemia
72020

University Hospital Freiburg

9.7/10
location_onGermany, Freibung

Department of Hematology and Oncology

The University Hospital Freiburg is famous for its rich history and is one of the oldest and most prestigious medical facilities in Germany (one of the three best medical institutions in the country). The hospital was based on the Faculty of Medicine of the Albert Ludwig University of Freiburg, which celebrated its 550th anniver
Acute Lymphoblastic Leukemia (ALL) Diagnosis
17463
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
291345
Consolidation treatment for acute lymphoblastic leukemia
88709

University Hospital Heidelberg

9.8/10
location_onGermany, Heidelberg

Department of Hematology, Oncology, Adult and Pediatric Rheumatology

According to the Focus magazine, the University Hospital Heidelberg ranks among the top five hospitals in Germany! The hospital is one of the most advanced and reputable medical institutions not only in Germany, but throughout Europe. There are more than 43 specialized departments and 13 medical institutes, which cover all field
Acute Lymphoblastic Leukemia (ALL) Diagnosis
0
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
0
Consolidation treatment for acute lymphoblastic leukemia
0

University Hospital Frankfurt am Main

10/10
location_onGermany, Frankfurt am Main

Department of Hematology, Oncology, Hemostaseology, Rheumatology and Infectology

According to the reputable Focus magazine, the University Hospital Frankfurt am Main ranks among the top German medical facilities! The hospital was founded in 1914 and today is a well-known German medical facility, which combines rich traditions and scientific innovations. A medical team of more than 6,500 employees cares about
Acute Lymphoblastic Leukemia (ALL) Diagnosis
15317
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
251851
Consolidation treatment for acute lymphoblastic leukemia
78509

University Hospital RWTH Aachen

8.7/10
location_onGermany, Aachen

Department of Oncology and Hematology

According to the prestigious Focus magazine, the University Hospital RWTH Aachen ranks among the top German hospitals! As a maximum care university medical facility, the hospital guarantees patients first-class medical services combined with a respectful and human attitude. The hospital integrates all the modern options for the
Acute Lymphoblastic Leukemia (ALL) Diagnosis
17098
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
291204
Consolidation treatment for acute lymphoblastic leukemia
88625

University Hospital Würzburg

9.2/10
location_onGermany, Würzburg

Department of Gastroenterology, Hematology, Oncology, Hepatology, Infectology, Rheumatology and Clinical Immunology

According to the Focus magazine in 2019, the University Hospital Würzburg ranks among the top national German hospitals! The hospital is one of the oldest medical facilities in Germany. The centuries-old traditions of first-class treatment are combined with the very latest achievements of modern evidence-based medicine and
Acute Lymphoblastic Leukemia (ALL) Diagnosis
14377
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
232109
Consolidation treatment for acute lymphoblastic leukemia
73317

University Hospital Erlangen

9.1/10
location_onGermany, Erlangen

Department of Hematology and Oncology

According to the Focus magazine, University Hospital Erlangen ranks among the best medical facilities in Germany! The hospital is one of the leading healthcare facilities in Bavaria and offers top-class medical care distinguished by the close intertwining of clinical activities with research and training of medical students. The
Acute Lymphoblastic Leukemia (ALL) Diagnosis
16376
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
271353
Consolidation treatment for acute lymphoblastic leukemia
72033

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of Hematology and Oncology

According to the prestigious Focus magazine, the University Hospital Halle (Saale) ranks among the top German medical facilities! The history of the hospital has more than 300 years, and during this time it managed to earn an excellent reputation not only in Germany, but throughout the world. The hospital positions itself as a s
Acute Lymphoblastic Leukemia (ALL) Diagnosis
14741
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
232143
Consolidation treatment for acute lymphoblastic leukemia
73254

University Hospital Hamburg-Eppendorf

9.2/10
location_onGermany, Hamburg

Department of Hematology, Oncology and Pulmonology

According to the Focus magazine, the University Hospital Hamburg-Eppendorf ranks among the top ten hospitals in Germany! Since its foundation in 1889, the hospital has taken a leading position in the European medical arena and still occupies it until today. A highly competent medical team of more than 11,000 employees takes care
Acute Lymphoblastic Leukemia (ALL) Diagnosis
14765
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
232075
Consolidation treatment for acute lymphoblastic leukemia
73084

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Charité Comprehensive Cancer Center

According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! The hospital is one of the largest and leading university medical complexes in Europe. The hospital in Germany provides modern diagnostics and treatment of patients, a
Acute Lymphoblastic Leukemia (ALL) Diagnosis
14403
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
231777
Consolidation treatment for acute lymphoblastic leukemia
72954

University Hospital Bonn

9.2/10
location_onGermany, Bonn

Department of Oncology, Hematology, Rheumatology and Immunoncology

According to the authoritative Focus magazine, the University Hospital Bonn ranks among the top ten medical facilities in Germany! The hospital was opened on January 1, 2001, although in fact it inherits the medical facility, which operated at the Faculty of Medicine of the University of Bonn. The hospital in Germany combin
Acute Lymphoblastic Leukemia (ALL) Diagnosis
17028
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
290938
Consolidation treatment for acute lymphoblastic leukemia
88785

University Hospital Giessen UKGM

9.5/10
location_onGermany, Giessen

Department of Oncology, Hematology and Palliative Care

The University Hospital Giessen UKGM positions itself as an ultramodern medical facility with outstanding quality of medical care. The hospital presents almost all areas of medicine, ranging from ophthalmology to traumatology and dentistry. The priorities of the hospital’s activities include surgery, neurosurgery, oncology
Acute Lymphoblastic Leukemia (ALL) Diagnosis
14738
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
232075
Consolidation treatment for acute lymphoblastic leukemia
72823

University Hospital of Ludwig Maximilian University of Munich

10/10
location_onGermany, Munich

Department of Oncology and Hematology

According to the Focus magazine, the University Hospital of Ludwig Maximilian University of Munich is regularly ranked among the best medical institutions in Germany! The hospital is the largest multidisciplinary medical facility, as well as a leading research and training center in Germany and Europe. The hospital is proud of i
Acute Lymphoblastic Leukemia (ALL) Diagnosis
17493
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
291161
Consolidation treatment for acute lymphoblastic leukemia
76600

University Hospital Marburg UKGM

8.6/10
location_onGermany, Marburg

Department of Hematology, Oncology and Immunology

The University Hospital Marburg UKGM offers patients modern diagnostics and comprehensive therapy at the international level. As a maximum care hospital, the medical facility specializes in all fields of modern medicine ranging from ophthalmology to traumatology and dentistry. The main areas of specialization of the hospital are
Acute Lymphoblastic Leukemia (ALL) Diagnosis
14683
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
232244
Consolidation treatment for acute lymphoblastic leukemia
73113

University Hospital Muenster

9.8/10
location_onGermany, Muenster

Department of Hematology, Hemostaseology, Oncology and Pulmonology

According to the Focus magazine, the University Hospital Muenster ranks among the top German hospitals! The hospital belongs to the most prestigious medical institutions in Germany. The hospital is distinguished by a high professionalism of its doctors, state-of-the-art technological equipment and the availability of the most ad
Acute Lymphoblastic Leukemia (ALL) Diagnosis
14689
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
231934
Consolidation treatment for acute lymphoblastic leukemia
73254
| from Booking Health GmbH

Acute lymphoblastic leukemia is a cancer that affects white blood cells (lymphocytes).

Stages of leukemia are early pre-B ALL, common ALL, pre-B(T) ALL, and mature B(T)-cell ALL.

Treatment includes chemo- and immunotherapy, irradiation, CAR T-cell therapy, and stem cell transplantation.

Cost of treatment with chemotherapy – from €43,781. Price for bone marrow transplantation – from €97,374. Cost of CAR T-cell therapy – from €81,970.

Best hospitals in Europe are:

  • University Hospital of Ludwig Maximilian University of Munich
  • University Hospital Rechts der Isar Munich
  • University Hospital Frankfurt am Main
  • Helios Hospital Berlin-Buch
  • Clinic of Advanced Biological Medicine Frankfurt am Main

About the disease

Acute lymphoblastic leukemia (ALL) affects the blood and bone marrow. This type of cancer creates abnormal blood cells, also known as immature blood cells. ALL mostly damages bone marrow, because this is where white blood cells are produced. ALL tends to develop very rapidly. It mostly affects children, although it can also develop in adults.

ALL mostly develops when abnormalities in DNA appear. As a result, healthy cells start to proliferate, becoming eventually malignant instead of dying and being replaced by new cells. When there are too many white blood cells circulating, they begin to produce lymphoblasts, which is a term for leukemic white blood cells. The reason why DNA becomes abnormal remains unknown. Certain genetic disorders are believed to contribute to the development of ALL, but this theory has not been proved yet.

Children who have previously undergone cancer treatments, such as chemotherapy or radiotherapy, have therefore been exposed to harmful radicals, making them an at-risk group.

According to Cancer Stat Facts, there were approximately 60,000 new cases of ALL in 2016. The 5-year survival rate for this type of cancer is 59.7%.

Symptoms

  • Bone pain
  • Paleness
  • Excessive bleeding from the gums
  • Headaches
  • Fever
  • Weight loss
  • Weakness
  • Nose bleeding

Diagnosis

  • A blood test is essential for diagnosing ALL. It can determine whether a person has too many white blood cells or if there are any immature cells that continue to proliferate and cause malignancy.
  • Bone marrow aspiration is used for a more detailed examination of the patient’s bone marrow. Usually, a sample of bone marrow is taken from the patient’s hip.
  • A CT and MRI scan of the patient’s brain is performed if there is reason to believe that ALL may have metastasized to the brain.

Treatment

  • High-intensity induction chemotherapy is used to kill as many malignant white blood cells and immature cellsб as possible. This aims to stop them from proliferating and to restore normal production of cells in the bone marrow. Depending on the stage the cancer has progressed to, doctors may prescribe 1 or 2 blocks of high-dose drugs.
  • Consolidation treatment is most commonly used after induction chemotherapy. Any remaining leukemic cells in the brain or brainstem are killed. It is mostly used at stages 2 and 3 of ALL.
  • Radiation therapy of the brain is performed if ALL has metastasized to the brain. In this case, doctors use high-intensity radiation to destroy malignant cells in the affected parts of the brain. 
  • A stem cells transplantation is performed if there is a high risk that cells will continue to proliferate and cause malignancy once the main treatment is finished. During this procedure, the affected bone marrow is replaced by healthy bone marrow from a donor.

Authors: Dr. Nadezhda IvanisovaDr. Farrukh Ahmed




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