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Diagnostic and treatment of Acute lymphoblastic leukemia

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Best hospitals and doctors for acute lymphoblastic leukemia treatment abroad

The selection of doctors and clinics is carried out on the basis of annual qualification reports. The main selection criterion is the number of operations or procedures performed. It takes into account experience, reputation in the medical society, the availability of quality certificates and high specialization in a certain field.

Cost for treatment

Acute Lymphoblastic Leukemia (ALL) Diagnosis
 from  10241
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
 from  172943
Consolidation treatment for acute lymphoblastic leukemia
 from  41334

University Hospital Mannheim

9.8/10
location_onGermany, Mannheim

Department of Hematology and Oncology

According to the reputable Focus magazine, the University Hospital Mannheim ranks among the top medical institutions of Germany, which is an undeniable confirmation of the impeccable medical care and excellent reputation of the hospital! The hospital is a high-tech modern medical institution, which provides accurate diagnosis an
Acute Lymphoblastic Leukemia (ALL) Diagnosis
14408
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
212317
Consolidation treatment for acute lymphoblastic leukemia
72809

University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of Hematology, Oncology, Palliative Care, Rheumatology and Infectology

The University Hospital Ulm started its activities 35 years ago and during this time it has become one of the most prestigious medical institutions in Europe. The hospital is famous for its numerous discoveries and the world-class achievements in medicine and pharmaceuticals. The medical facility has 29 specialized departments a
Acute Lymphoblastic Leukemia (ALL) Diagnosis
16610
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
271677
Consolidation treatment for acute lymphoblastic leukemia
72020

Medicana International Ankara Hospital

9/10
location_onTurkey, Ankara

Department of Hematology and Bone Marrow Transplantation

The Medicana International Ankara Hospital is one of the leading medical centers, which belongs to the largest medical network Medicana in Turkey. The hospital incorporates all specialties of the modern medicine under one roof. It particularly focuses on bone marrow transplantation, cardiology, cardiovascular surg
Acute Lymphoblastic Leukemia (ALL) Diagnosis
11748
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
173111
Consolidation treatment for acute lymphoblastic leukemia
50286

Samsung Medical Center Seoul

9.8/10
location_onSouth Korea, Seoul

Department of Oncology and Hematology

The Samsung Medical Center was founded in 1994 and soon won the reputation of a medical facility of presidential standards, which it still preserves today. The hospital has 40 departments, 10 specialized centers and a huge Cancer Center with 655 beds. The medical facility is equipped with advanced equipment (for example, a 32-ch
Acute Lymphoblastic Leukemia (ALL) Diagnosis
15238.6 help13803
Consolidation treatment for acute lymphoblastic leukemia
67408.6 help58984
High-intensity induction chemotherapy of acute lymphoblastic leukemia with complications
67237.8 help58781

Tel Aviv Sourasky Medical Center

9.9/10
location_onIsrael, Tel Aviv

Department of Hematology

The Tel Aviv Sourasky Medical Center is the second largest and one of the most advanced healthcare and research facilities in Israel. It began its work in 1961, but it is still popular among the local population and attracts thousands of international patients. The multidisciplinary medical center covers an area of ​​150,000 m&s
Acute Lymphoblastic Leukemia (ALL) Diagnosis
17313
Consolidation treatment for acute lymphoblastic leukemia
76765
High-intensity induction chemotherapy of acute lymphoblastic leukemia with complications
76612

University Hospital Freiburg

9.7/10
location_onGermany, Freibung

Department of Hematology and Oncology

The University Hospital Freiburg is famous for its rich history and is one of the oldest and most prestigious medical facilities in Germany (one of the three best medical institutions in the country). The hospital was based on the Faculty of Medicine of the Albert Ludwig University of Freiburg, which celebrated its 550th anniver
Acute Lymphoblastic Leukemia (ALL) Diagnosis
17463
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
291473
Consolidation treatment for acute lymphoblastic leukemia
88709

University Hospital Heidelberg

9.8/10
location_onGermany, Heidelberg

Department of Hematology, Oncology, Adult and Pediatric Rheumatology

According to the Focus magazine, the University Hospital Heidelberg ranks among the top five hospitals in Germany! The hospital is one of the most advanced and reputable medical institutions not only in Germany, but throughout Europe. There are more than 43 specialized departments and 13 medical institutes, which cover all field
Acute Lymphoblastic Leukemia (ALL) Diagnosis
0
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
0
Consolidation treatment for acute lymphoblastic leukemia
0

University Hospital Würzburg

9.2/10
location_onGermany, Würzburg

Department of Gastroenterology, Hematology, Oncology, Hepatology, Infectology, Rheumatology and Clinical Immunology

According to the Focus magazine in 2019, the University Hospital Würzburg ranks among the top national German hospitals! The hospital is one of the oldest medical facilities in Germany. The centuries-old traditions of first-class treatment are combined with the very latest achievements of modern evidence-based medicine and
Acute Lymphoblastic Leukemia (ALL) Diagnosis
14377
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
232033
Consolidation treatment for acute lymphoblastic leukemia
73317

University Hospital RWTH Aachen

8.7/10
location_onGermany, Aachen

Department of Oncology and Hematology

According to the prestigious Focus magazine, the University Hospital RWTH Aachen ranks among the top German hospitals! As a maximum care university medical facility, the hospital guarantees patients first-class medical services combined with a respectful and human attitude. The hospital integrates all the modern options for the
Acute Lymphoblastic Leukemia (ALL) Diagnosis
17098
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
291252
Consolidation treatment for acute lymphoblastic leukemia
88625

University Hospital Erlangen

9.1/10
location_onGermany, Erlangen

Department of Hematology and Oncology

According to the Focus magazine, the University Hospital Erlangen ranks among the top German medical facilities! The hospital is one of the leading medical facilities in Bavaria and offers the highest level of medical care, which is characterized by the close intertwining of clinical activities with research and training of medi
Acute Lymphoblastic Leukemia (ALL) Diagnosis
16376
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
271698
Consolidation treatment for acute lymphoblastic leukemia
72033

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of Hematology and Oncology

According to the prestigious Focus magazine, the University Hospital Halle (Saale) ranks among the top German medical facilities! The history of the hospital has more than 300 years, and during this time it managed to earn an excellent reputation not only in Germany, but throughout the world. The hospital positions itself as a s
Acute Lymphoblastic Leukemia (ALL) Diagnosis
14741
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
231862
Consolidation treatment for acute lymphoblastic leukemia
73254

University Hospital Hamburg-Eppendorf

9.2/10
location_onGermany, Hamburg

Department of Hematology, Oncology and Pulmonology

According to the Focus magazine, the University Hospital Hamburg-Eppendorf ranks among the top ten hospitals in Germany! Since its foundation in 1889, the hospital has taken a leading position in the European medical arena and still occupies it until today. A highly competent medical team of more than 11,000 employees takes care
Acute Lymphoblastic Leukemia (ALL) Diagnosis
14765
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
232226
Consolidation treatment for acute lymphoblastic leukemia
73084

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Charité Comprehensive Cancer Center

According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! The hospital is one of the largest and leading university medical complexes in Europe. The hospital in Germany provides modern diagnostics and treatment of patients, a
Acute Lymphoblastic Leukemia (ALL) Diagnosis
14403
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
231900
Consolidation treatment for acute lymphoblastic leukemia
72954

University Hospital Bonn

9.2/10
location_onGermany, Bonn

Department of Oncology, Hematology, Rheumatology and Immunoncology

According to the authoritative Focus magazine, the University Hospital Bonn ranks among the top ten medical facilities in Germany! The hospital was opened on January 1, 2001, although in fact it inherits the medical facility, which operated at the Faculty of Medicine of the University of Bonn. The hospital in Germany combin
Acute Lymphoblastic Leukemia (ALL) Diagnosis
17028
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
291457
Consolidation treatment for acute lymphoblastic leukemia
88785

University Hospital of Ludwig Maximilian University of Munich

10/10
location_onGermany, Munich

Department of Oncology and Hematology

According to the Focus magazine, the University Hospital of Ludwig Maximilian University of Munich is regularly ranked among the best medical institutions in Germany! The hospital is the largest multidisciplinary medical facility, as well as a leading research and training center in Germany and Europe. The hospital is proud of i
Acute Lymphoblastic Leukemia (ALL) Diagnosis
17493
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
291373
Consolidation treatment for acute lymphoblastic leukemia
76600

University Hospital Giessen UKGM

9.5/10
location_onGermany, Giessen

Department of Oncology, Hematology and Palliative Care

The University Hospital Giessen UKGM positions itself as an ultramodern medical facility with outstanding quality of medical care. The hospital presents almost all areas of medicine, ranging from ophthalmology to traumatology and dentistry. The priorities of the hospital’s activities include surgery, neurosurgery, oncology
Acute Lymphoblastic Leukemia (ALL) Diagnosis
14738
Allogeneic bone marrow transplantation in acute lymphoblastic leukemia
231760
Consolidation treatment for acute lymphoblastic leukemia
72823

About the disease

Acute lymphoblastic leukemia (ALL) affects the blood and bone marrow. This type of cancer creates abnormal blood cells, also known as immature blood cells. ALL mostly damages bone marrow, because this is where white blood cells are produced. ALL tends to develop very rapidly. It mostly affects children, although it can also develop in adults.

ALL mostly develops when abnormalities in DNA appear. As a result, healthy cells start to proliferate, becoming eventually malignant instead of dying and being replaced by new cells. When there are too many white blood cells circulating, they begin to produce lymphoblasts, which is a term for leukemic white blood cells. The reason why DNA becomes abnormal remains unknown. Certain genetic disorders are believed to contribute to the development of ALL, but this theory has not been proved yet.

Children who have previously undergone cancer treatments, such as chemotherapy or radiotherapy, have therefore been exposed to harmful radicals, making them an at-risk group.

According to Cancer Stat Facts, there were approximately 60,000 new cases of ALL in 2016. The 5-year survival rate for this type of cancer is 59.7%.

Symptoms

  • Bone pain
  • Paleness
  • Excessive bleeding from the gums
  • Headaches
  • Fever
  • Weight loss
  • Weakness
  • Nose bleeding

Diagnosis

  • A blood test is essential for diagnosing ALL. It can determine whether a person has too many white blood cells or if there are any immature cells that continue to proliferate and cause malignancy.
  • Bone marrow aspiration is used for a more detailed examination of the patient’s bone marrow. Usually, a sample of bone marrow is taken from the patient’s hip.
  • A CT and MRI scan of the patient’s brain is performed if there is reason to believe that ALL may have metastasized to the brain.

Treatment

  • High-intensity induction chemotherapy is used to kill as many malignant white blood cells and immature cellsб as possible. This aims to stop them from proliferating and to restore normal production of cells in the bone marrow. Depending on the stage the cancer has progressed to, doctors may prescribe 1 or 2 blocks of high-dose drugs.
  • Consolidation treatment is most commonly used after induction chemotherapy. Any remaining leukemic cells in the brain or brainstem are killed. It is mostly used at stages 2 and 3 of ALL.
  • Radiation therapy of the brain is performed if ALL has metastasized to the brain. In this case, doctors use high-intensity radiation to destroy malignant cells in the affected parts of the brain. 
  • A stem cells transplantation is performed if there is a high risk that cells will continue to proliferate and cause malignancy once the main treatment is finished. During this procedure, the affected bone marrow is replaced by healthy bone marrow from a donor.

 

Author: Dr. Nadezhda Ivanisova

 




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