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Diagnostic and treatment of Aplastic anemia

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Cost for treatment

Aplastic Anemia Diagnosis
 from  2653
Allogeneic bone marrow transplantation (stem cell transplant) in aplastic anemia
 from  97133
Diagnosis and treatment of aplastic anemia by immunosuppressive therapy
 from  3827

University Hospital Mannheim

9.8/10
location_onGermany, Mannheim

Department of Hematology and Oncology

According to the reputable Focus magazine, the University Hospital Mannheim ranks among the top medical institutions of Germany, which is an undeniable confirmation of the impeccable medical care and excellent reputation of the hospital! The hospital is a high-tech modern medical institution, which provides accurate diagnosis an
Aplastic Anemia Diagnosis
4946
Allogeneic bone marrow transplantation (stem cell transplant) in aplastic anemia
212180
Diagnosis and treatment of aplastic anemia by immunosuppressive therapy
7455

University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of Hematology, Oncology, Palliative Care, Rheumatology and Infectology

The University Hospital Ulm started its activities 35 years ago and during this time it has become one of the most prestigious medical institutions in Europe. The hospital is famous for its numerous discoveries and the world-class achievements in medicine and pharmaceuticals. The medical facility has 29 specialized departments a
Aplastic Anemia Diagnosis
5514
Allogeneic bone marrow transplantation (stem cell transplant) in aplastic anemia
271656
Diagnosis and treatment of aplastic anemia by immunosuppressive therapy
8222

University Hospital Freiburg

9.7/10
location_onGermany, Freibung

Department of Hematology and Oncology

The University Hospital Freiburg is famous for its rich history and is one of the oldest and most prestigious medical facilities in Germany (one of the three best medical institutions in the country). The hospital was based on the Faculty of Medicine of the Albert Ludwig University of Freiburg, which celebrated its 550th anniver
Aplastic Anemia Diagnosis
5891
Allogeneic bone marrow transplantation (stem cell transplant) in aplastic anemia
290972
Diagnosis and treatment of aplastic anemia by immunosuppressive therapy
8486

University Hospital Heidelberg

9.8/10
location_onGermany, Heidelberg

Department of Hematology, Oncology, Adult and Pediatric Rheumatology

According to the Focus magazine, the University Hospital Heidelberg ranks among the top five hospitals in Germany! The hospital is one of the most advanced and reputable medical institutions not only in Germany, but throughout Europe. There are more than 43 specialized departments and 13 medical institutes, which cover all field
Aplastic Anemia Diagnosis
0
Allogeneic bone marrow transplantation (stem cell transplant) in aplastic anemia
0
Diagnosis and treatment of aplastic anemia by immunosuppressive therapy
0

University Hospital Frankfurt am Main

10/10
location_onGermany, Frankfurt am Main

Department of Hematology, Oncology, Hemostaseology, Rheumatology and Infectology

According to the reputable Focus magazine, the University Hospital Frankfurt am Main ranks among the top German medical facilities! The hospital was founded in 1914 and today is a well-known German medical facility, which combines rich traditions and scientific innovations. A medical team of more than 6,500 employees cares about
Aplastic Anemia Diagnosis
5309
Allogeneic bone marrow transplantation (stem cell transplant) in aplastic anemia
252034
Diagnosis and treatment of aplastic anemia by immunosuppressive therapy
7702

University Hospital RWTH Aachen

8.7/10
location_onGermany, Aachen

Department of Oncology and Hematology

According to the prestigious Focus magazine, the University Hospital RWTH Aachen ranks among the top German hospitals! As a maximum care university medical facility, the hospital guarantees patients first-class medical services combined with a respectful and human attitude. The hospital integrates all the modern options for the
Aplastic Anemia Diagnosis
5878
Allogeneic bone marrow transplantation (stem cell transplant) in aplastic anemia
291211
Diagnosis and treatment of aplastic anemia by immunosuppressive therapy
8535

University Hospital Würzburg

9.2/10
location_onGermany, Würzburg

Department of Gastroenterology, Hematology, Oncology, Hepatology, Infectology, Rheumatology and Clinical Immunology

According to the Focus magazine in 2019, the University Hospital Würzburg ranks among the top national German hospitals! The hospital is one of the oldest medical facilities in Germany. The centuries-old traditions of first-class treatment are combined with the very latest achievements of modern evidence-based medicine and
Aplastic Anemia Diagnosis
5028
Allogeneic bone marrow transplantation (stem cell transplant) in aplastic anemia
232322
Diagnosis and treatment of aplastic anemia by immunosuppressive therapy
7351

University Hospital Erlangen

9.1/10
location_onGermany, Erlangen

Department of Hematology and Oncology

According to the Focus magazine, the University Hospital Erlangen ranks among the top German medical facilities! The hospital is one of the leading medical facilities in Bavaria and offers the highest level of medical care, which is characterized by the close intertwining of clinical activities with research and training of medi
Aplastic Anemia Diagnosis
5424
Allogeneic bone marrow transplantation (stem cell transplant) in aplastic anemia
271263
Diagnosis and treatment of aplastic anemia by immunosuppressive therapy
8226

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of Hematology and Oncology

According to the prestigious Focus magazine, the University Hospital Halle (Saale) ranks among the top German medical facilities! The history of the hospital has more than 300 years, and during this time it managed to earn an excellent reputation not only in Germany, but throughout the world. The hospital positions itself as a s
Aplastic Anemia Diagnosis
5078
Allogeneic bone marrow transplantation (stem cell transplant) in aplastic anemia
231988
Diagnosis and treatment of aplastic anemia by immunosuppressive therapy
7323

University Hospital Hamburg-Eppendorf

9.2/10
location_onGermany, Hamburg

Department of Hematology, Oncology and Pulmonology

According to the Focus magazine, the University Hospital Hamburg-Eppendorf ranks among the top ten hospitals in Germany! Since its foundation in 1889, the hospital has taken a leading position in the European medical arena and still occupies it until today. A highly competent medical team of more than 11,000 employees takes care
Aplastic Anemia Diagnosis
4880
Allogeneic bone marrow transplantation (stem cell transplant) in aplastic anemia
232250
Diagnosis and treatment of aplastic anemia by immunosuppressive therapy
7373

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Charité Comprehensive Cancer Center

According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! The hospital is one of the largest and leading university medical complexes in Europe. The hospital in Germany provides modern diagnostics and treatment of patients, a
Aplastic Anemia Diagnosis
5067
Allogeneic bone marrow transplantation (stem cell transplant) in aplastic anemia
231945
Diagnosis and treatment of aplastic anemia by immunosuppressive therapy
7461

University Hospital Bonn

9.2/10
location_onGermany, Bonn

Department of Oncology, Hematology, Rheumatology and Immunoncology

According to the authoritative Focus magazine, the University Hospital Bonn ranks among the top ten medical facilities in Germany! The hospital was opened on January 1, 2001, although in fact it inherits the medical facility, which operated at the Faculty of Medicine of the University of Bonn. The hospital in Germany combin
Aplastic Anemia Diagnosis
5784
Allogeneic bone marrow transplantation (stem cell transplant) in aplastic anemia
290966
Diagnosis and treatment of aplastic anemia by immunosuppressive therapy
8490

University Hospital Giessen UKGM

9.5/10
location_onGermany, Giessen

Department of Oncology, Hematology and Palliative Care

The University Hospital Giessen UKGM positions itself as an ultramodern medical facility with outstanding quality of medical care. The hospital presents almost all areas of medicine, ranging from ophthalmology to traumatology and dentistry. The priorities of the hospital’s activities include surgery, neurosurgery, oncology
Aplastic Anemia Diagnosis
5011
Allogeneic bone marrow transplantation (stem cell transplant) in aplastic anemia
231766
Diagnosis and treatment of aplastic anemia by immunosuppressive therapy
7306

University Hospital of Ludwig Maximilian University of Munich

10/10
location_onGermany, Munich

Department of Oncology and Hematology

According to the Focus magazine, the University Hospital of Ludwig Maximilian University of Munich is regularly ranked among the best medical institutions in Germany! The hospital is the largest multidisciplinary medical facility, as well as a leading research and training center in Germany and Europe. The hospital is proud of i
Aplastic Anemia Diagnosis
5853
Allogeneic bone marrow transplantation (stem cell transplant) in aplastic anemia
291160
Diagnosis and treatment of aplastic anemia by immunosuppressive therapy
8386

University Hospital Marburg UKGM

8.6/10
location_onGermany, Marburg

Department of Hematology, Oncology and Immunology

The University Hospital Marburg UKGM offers patients modern diagnostics and comprehensive therapy at the international level. As a maximum care hospital, the medical facility specializes in all fields of modern medicine ranging from ophthalmology to traumatology and dentistry. The main areas of specialization of the hospital are
Aplastic Anemia Diagnosis
4909
Allogeneic bone marrow transplantation (stem cell transplant) in aplastic anemia
232131
Diagnosis and treatment of aplastic anemia by immunosuppressive therapy
7429

University Hospital Muenster

9.8/10
location_onGermany, Muenster

Department of Hematology, Hemostaseology, Oncology and Pulmonology

According to the Focus magazine, the University Hospital Muenster ranks among the top German hospitals! The hospital belongs to the most prestigious medical institutions in Germany. The hospital is distinguished by a high professionalism of its doctors, state-of-the-art technological equipment and the availability of the most ad
Aplastic Anemia Diagnosis
5078
Allogeneic bone marrow transplantation (stem cell transplant) in aplastic anemia
231868
Diagnosis and treatment of aplastic anemia by immunosuppressive therapy
7308
| from Booking Health GmbH

About the disease

Aplastic anemia is a disease, when body is not able to produce sufficient amount of new blood cells. As a result, person feels fatigue and weakness, is more exposed to different infections and any uncontrollable bleeding can become a medical emergency. Aplastic anemia is considered to be a rare condition, which can generally develop at any age. It can develop gradually and the onset can be sudden, causing more pronounced symptoms. 

Aplastic anemia arises when bone marrow stops producing sufficient amount of white and red blood cells. These blood cells are produced from the stem cells, which are located in the bone marrow. There can be not enough stem cells produced if a person has been exposed to the radioactive and chemical agents for a long time (e.g. during the cancer treatment). Exposure to certain toxic chemicals, such as gasoline, can also result in development of aplastic anemia.

People with autoimmune disorders, which attack stem cells, are more likely to develop aplastic anemia in future. Viral infections, such as hepatitis of different types, can also affect production of new blood cells. In rare cases pregnancy can be a provoking factor in women, who already have autoimmune disorders.

Symptoms

  • Fatigue
  • Pale skin
  • Weight loss
  • Frequent and recurrent infections
  • Prolonged bleeding from nose or sores
  • Unexplained bruises, which appeared without any previous falls or injuries
  • Headaches
  • Dizziness
  • Nausea
  • Loss of consciousness
  • Low blood pressure

Diagnosis

  • Blood test is usually enough to diagnose aplastic anemia, as it allows to assess the amount of platelets, white and red blood cells.
  • Biopsy of bone marrow is mainly used if there is suspicion of cancer, which sometimes has similar symptoms. Sample tissue is usually taken from the hip bone, where bone marrow is the most accessible.

Treatment

  • Allogeneic bone marrow transplantation is a surgery used to remove the old bone marrow and transplant the new one from a donor with genetically similar stem cells. It is used when conservative treatment is unable to renew the normal production of blood cells.
  • Immunosuppressive therapy is used if aplastic anemia was caused by certain autoimmune disorders. In this case, immune system is partially blocked to allow the bone marrow produce sufficient amount of stem cells. During the course of treatment patients need to be extra cautious to avoid infections and viral diseases, as their immune system won't be able to fight them in a proper way.

Authors: Dr. Nadezhda IvanisovaDr. Farrukh Ahmed




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