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Treatment of Breast cancer

Due to the difficulties associated with the organization of treatment in Turkey, Switzerland and South Korea, we have currently suspended the processing of requests to these regions.

If you are interested in treatment in Germany, please leave a request and our specialists will contact you as soon as possible.

 

Cost for treatment

Breast cancer diagnosis
 from  642
Sectoral resection in breast cancer with flap plastic
 from  3696
Radical mastectomy in breast cancer
 from  4140

University Hospital Tuebingen

9.2/10
location_onGermany, Tuebingen

Department of Adult and Pediatric Gynecology, Mammology, Obstetrics

According to the prestigious medical publication Focus, the University Hospital Tuebingen ranks among the top five German hospitals! The hospital was founded in 1805, therefore it is proud of its long history, unique experience, and outstanding achievements in the field of medical care, as well as research and teaching activitie
Breast cancer diagnosis
1977
Sectoral resection in breast cancer with flap plastic
12103
Radical mastectomy in breast cancer
12859

University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of Obstetrics, Adult and Pediatric Gynecology

The University Hospital Ulm started its activities 35 years ago and during this time it has become one of the most prestigious medical institutions in Europe. The hospital is famous for its numerous discoveries and the world-class achievements in medicine and pharmaceuticals. The medical facility has 29 specialized departments a
Breast cancer diagnosis
2104
Sectoral resection in breast cancer with flap plastic
12068
Radical mastectomy in breast cancer
12628

University Hospital Frankfurt am Main

10/10
location_onGermany, Frankfurt am Main

Department of Adult and Pediatric Gynecology, Obstetrics and Mammology

According to the reputable Focus magazine, the University Hospital Frankfurt am Main ranks among the top German medical facilities! The hospital was founded in 1914 and today is a well-known German medical facility, which combines rich traditions and scientific innovations. A medical team of more than 6,500 employees cares about
Breast cancer diagnosis
2115
Sectoral resection in breast cancer with flap plastic
11376
Radical mastectomy in breast cancer
12107

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Department of Adult and Pediatric Gynecology, Mammology

According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! The hospital is one of the largest and leading university medical complexes in Europe. The hospital in Germany provides modern diagnostics and treatment of patients, a
Breast cancer diagnosis
2940
Sectoral resection in breast cancer with flap plastic
16430
Radical mastectomy in breast cancer
17650

University Hospital Muenster

9.8/10
location_onGermany, Muenster

Department of Mammology

According to the Focus magazine, the University Hospital Muenster ranks among the top German hospitals! The hospital belongs to the most prestigious medical institutions in Germany. The hospital is distinguished by a high professionalism of its doctors, state-of-the-art technological equipment and the availability of the most ad
Breast cancer diagnosis
2131
Sectoral resection in breast cancer with flap plastic
11244
Radical mastectomy in breast cancer
11959

University Hospital Erlangen

9.1/10
location_onGermany, Erlangen

Department of Gynecology, Obstetrics and Mammology

According to the Focus magazine, the University Hospital Erlangen ranks among the top German medical facilities! The hospital is one of the leading medical facilities in Bavaria and offers the highest level of medical care, which is characterized by the close intertwining of clinical activities with research and training of medi
Breast cancer diagnosis
1973
Sectoral resection in breast cancer with flap plastic
12021
Radical mastectomy in breast cancer
12636

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of Gynecology and Mammology

According to the prestigious Focus magazine, the University Hospital Halle (Saale) ranks among the top German medical facilities! The history of the hospital has more than 300 years, and during this time it managed to earn an excellent reputation not only in Germany, but throughout the world. The hospital positions itself as a s
Breast cancer diagnosis
2156
Sectoral resection in breast cancer with flap plastic
11636
Radical mastectomy in breast cancer
12080

University Hospital Hamburg-Eppendorf

9.2/10
location_onGermany, Hamburg

Department of Gynecology and Mammology

According to the Focus magazine, the University Hospital Hamburg-Eppendorf ranks among the top ten hospitals in Germany! Since its foundation in 1889, the hospital has taken a leading position in the European medical arena and still occupies it until today. A highly competent medical team of more than 11,000 employees takes care
Breast cancer diagnosis
2649
Sectoral resection in breast cancer with flap plastic
14840
Radical mastectomy in breast cancer
15730

University Hospital RWTH Aachen

8.9/10
location_onGermany, Aachen

Department of Gynecology, Mammology and Obstetrics

According to the prestigious Focus magazine, the University Hospital RWTH Aachen ranks among the top German hospitals! As a maximum care university medical facility, the hospital guarantees patients first-class medical services combined with a respectful and human attitude. The hospital integrates all the modern options for the
Breast cancer diagnosis
2310
Sectoral resection in breast cancer with flap plastic
12659
Radical mastectomy in breast cancer
13575

University Hospital Würzburg

9.2/10
location_onGermany, Würzburg

Department of Adult and Pediatric Gynecology, Mammology and Obstetrics

According to the Focus magazine in 2019, the University Hospital Würzburg ranks among the top national German hospitals! The hospital is one of the oldest medical facilities in Germany. The centuries-old traditions of first-class treatment are combined with the very latest achievements of modern evidence-based medicine and
Breast cancer diagnosis
2090
Sectoral resection in breast cancer with flap plastic
11541
Radical mastectomy in breast cancer
12090

University Hospital Rechts der Isar Munich

9.8/10
location_onGermany, Munich

Department of Gynecology, Mammology, Obstetrics and Perinatal Medicine

According to the prestigious FOCUS magazine, the University Hospital Rechts der Isar Munich ranks among the Germany's top medical institutions! Founded in 1834, the hospital combines long traditions and the very latest achievements of modern medicine. The medical facility includes 33 specialized departments, 20 interdiscipli
Breast cancer diagnosis
2327
Sectoral resection in breast cancer with flap plastic
12040
Radical mastectomy in breast cancer
12800

University Hospital Heidelberg

9.8/10
location_onGermany, Heidelberg

Department of Mammology

According to the Focus magazine, the University Hospital Heidelberg ranks among the top five hospitals in Germany! The hospital is one of the most advanced and reputable medical institutions not only in Germany, but throughout Europe. There are more than 43 specialized departments and 13 medical institutes, which cover all field
Breast cancer diagnosis
0
Sectoral resection in breast cancer with flap plastic
0
Radical mastectomy in breast cancer
0

University Hospital Duesseldorf

9.5/10
location_onGermany, Duesseldorf

Department of Adult and Pediatric Gynecology, Obstetrics and Mammology

According to the authoritative Focus magazine, the University Hospital Duesseldorf ranks among the top Germany hospitals! The hospital is an excellent example of a combination of high-quality health care, research and teaching activities. With more than 50,000 inpatients and about 300,000 outpatients every year, the hospital is
Breast cancer diagnosis
2312
Sectoral resection in breast cancer with flap plastic
12609
Radical mastectomy in breast cancer
13409

University Hospital of Ludwig Maximilian University of Munich

10/10
location_onGermany, Munich

Breast Center

According to the Focus magazine, the University Hospital of Ludwig Maximilian University of Munich is regularly ranked among the best medical institutions in Germany! The hospital is the largest multidisciplinary medical facility, as well as a leading research and training center in Germany and Europe. The hospital is proud of i
Breast cancer diagnosis
2176
Sectoral resection in breast cancer with flap plastic
12690
Radical mastectomy in breast cancer
13259

University Hospital Oldenburg

10/10
location_onGermany, Oldenburg

Department of Mammology, Gynecology and Obstetrics

According to the Focus magazine, the University Hospital Oldenburg ranks among the best medical facilities in Germany! The hospital offers a wide range of medical services that meet the highest medical standards. The hospital has 832 beds. The medical facility annually serves 37,000 patients on an inpatient and partially inpatie
Breast cancer diagnosis
1749
Sectoral resection in breast cancer with flap plastic
10103
Radical mastectomy in breast cancer
10765

PAN Clinic Cologne

10/10
location_onGermany, Cologne

Department of Mammology and Breast Surgery

The PAN Clinic Cologne is a multidisciplinary medical facility that combines advanced medicine, excellent quality of patient care and a high level of comfort. Founded in 1999, the clinic is located in the very heart of Cologne. During this time, the medical complex has gained long clinical experience, but at the same time it has
Breast cancer diagnosis
2301
Sectoral resection in breast cancer with flap plastic
11932
Radical mastectomy in breast cancer
12727
| from Booking Health GmbH

Content

  1. Stages of breast cancer
  2. Factors influencing the treatment and prognosis
  3. Surgery
  4. Chemotherapy
  5. Radiation therapy
  6. Stage 4 breast cancer treatment options
  7. Clinical trials
  8. Best hospital for breast cancer treatment abroad
  9. Prices for treatment abroad
  10. Why undergoing treatment with Booking Health?

 

Most tumors that arise in the breasts are benign and not considered dangerous. Their cells do not differ significantly from healthy ones, and they do not interfere with functioning of the organs or spread to distant body parts.

Breast cancer develops due to atypical molecular changes that regulate normal cell growth. Malignant cells multiply uncontrollably, so over time they can overgrow the original localization and spread to surrounding healthy tissues and distant organs.

Stages of breast cancer

 

Stage 1 and 2 breast cancers are called early-stage or localized cancers. At the first stage, a tumor is less than 2 cm in diameter and doesn't affect the lymph nodes. At the second stage, the tumor spreads to the axillary lymph nodes and/or the tumor is larger than 2 cm (up to 5 cm).

Stage 3 breast cancer is also called locally advanced cancer. It is characterized by a large tumor (more than 5 cm in diameter), metastasizing to the axillary lymph nodes, the involvement of intramammary, supra- and subclavian lymph nodes. At this stage, the tumor may invade the muscle tissue under the breast.

Inflammatory breast cancer is a fast-growing type of tumor that causes redness and inflammation of the breast. It is classified as stage 3 breast cancer, even if the tumor is small and the lymph nodes are not affected.

At stage 4 breast cancer, the tumor metastasizes to distant organs (bones, lungs, liver, etc). In this case, the size of the initial tumor and the degree of damage to the lymph nodes aren’t the important criteria.

Factors influencing the treatment and prognosis

 

Today, breast cancer treatment is personalized. It depends not only on the stage but also on the biological subtype of cancer.

Tumors that express sex hormone receptors and do not express HER2 (human epidermal growth factor receptor 2) have a more favorable clinical course. These tumors tend to respond well to hormone therapy and have better prognosis.

Triple negative breast cancer is a tumor with no receptors for hormones and HER2. As a rule, in these tumors, cells are dividing very quickly. Triple negative breast cancer has the most unfavorable prognosis and an extremely high metastatic potential. On the other hand, such tumors are most sensitive to chemotherapeutic agents.

Hereditary breast cancer risk group should be taken into account as a prognostic factor as well.

The most common early-stage cancer treatment is surgery.

Metastatic breast cancer is cancer that spreads to lymph nodes or distant body parts.

The best treatment for stage 4 breast cancer is radiation therapy, chemotherapy, targeted therapy, and hormonal therapy.

Cost of treatment with sectoral resection starts at €3,696. Price for radical mastectomy starts at €4,140. Cost of chemotherapy starts at €2,483.

The best hospitals for breast cancer treatment in Europe are:

  • University Hospital Rechts der Isar Munich
  • University Hospital Frankfurt am Main
  • University Hospital of Ludwig Maximilian University of Munich
  • Helios Hospital Berlin-Buch
  • Clinic of Advanced Biological Medicine Frankfurt am Main

Surgery

 

Surgery is still one of the main breast cancer treatment options.

Over the past decade, surgery has become more widespread and actively used. This is explained by the fact that the long-term results of radical operations are almost not inferior to the results of surgical treatments using organ-preserving and reconstructive techniques.

When choosing the volume of a surgical intervention, it is necessary to assess all the indications and contraindications and take into account the features of breast cancer.

Today, the following surgical techniques are widely used:

  • Removal of a tumor within healthy tissues (lumpectomy) with the removal of lymph nodes
  • Lumpectomy and simultaneous reconstruction of the shape and volume of the mammary gland
  • Complete subcutaneous removal of the mammary gland with or without preservation of the nipple and areola with reconstruction with a silicone implant

Although surgery remains the main method of treatment, patients who undergo breast-conserving surgery should receive additional treatments, which may include systemic chemotherapy, radiation therapy, and hormone therapy.

Chemotherapy

 

Usually, chemotherapy is performed before or after surgery. Its regimen is selected according to histological and immunohistochemical peculiarities of the malignant neoplasm.

The low-risk group includes patients who have tumors with high hormonal sensitivity, less than 2 cm in diameter, and a high degree of tumor differentiation. The high-risk group includes patients who have hormonally insensitive tumors, with a neoplasm exceeding 2 cm size, and a moderate and low degree of tumor differentiation.

Chemotherapy implies using of specific medications designed for:

  • Diminishing a tumor volume
  • Improving the long-term result of surgical interventions
  • Eradicating micrometastases
  • Increasing duration of the relapse-free period

Over the years, chemotherapy has significantly strengthened its position in breast cancer treatment. This is primarily because of good results in breast cancer treatment in the preoperative period (neoadjuvant chemotherapy), the life expectancy increase after therapy, and a decrease in the risk of tumor recurrence after treatments.

Radiation therapy

 

Radiation therapy is considered one of the fundamental breast cancer treatments. The potency of radiation therapy is explained by the tumor sensitivity to ionizing rays. After irradiation, tumor cells are either destroyed or lose their ability to reproduce.

Applied at early stages, radiation therapy can contribute to the tumor destruction, reducing the chance of recurrence by more than 50%. With timely diagnosis making and proper treatment tactics, more than 80% of patients can be cured.

The technique of radiation therapy is constantly being improved in order to reduce the negative impact of rays on the human body.

Stage 4 breast cancer treatment options

 

Radical surgery at this stage is usually not possible, because in patients with stage 4 breast cancer metastases are present, and most of them are very small. However, palliative surgery still belongs to the stage 4 breast cancer treatment options, as it facilitates managing the symptoms of stage 4 metastatic breast cancer, enhances a woman's condition, and increases life expectancy. To eliminate the hormonal effects in stage 4 metastatic breast cancer, ovarian removal (oophorectomy) is sometimes performed as well.

Among stage 4 breast cancer treatment options, chemotherapy is considered one of the first-line treatments. The doctor may prescribe one chemotherapy drug or a multi-drug therapy. Chemotherapy for stage 4 breast cancer treatment is carried out in cycles with several breaks that are necessary to restore a patient's health condition.

In more than half patients with stage 4 metastatic breast cancer tumor cells are sensitive to female sex hormones. Such type of stage 4 breast cancer is responsive to hormone therapy. Therefore, various hormonal drugs are used for stage 4 breast cancer treatment.

In stage 4 metastatic breast cancer, a malignant focus often has an excess amount of specific receptor protein on its surface called HER2. When activated, it induces malignant cells to multiply. Currently, targeted drugs are available that block this receptor. During stage 4 breast cancer treatment such blockers are sometimes combined with chemotherapy. Suchlike treatment continues as long as the tumor responds to medication. For stage 4 breast cancer that responds to the mentioned blockers, targeted therapy is prescribed along with chemotherapy or hormone therapy.

So, in hormone-sensitive stage 4 breast cancer hormonal drugs can be used in combination with targeted ones. Time is needed for the effect of hormone therapy to become noticeable, sometimes as long as several months. However, if severe symptoms that have to be eliminated quickly are observed, treatment starts with chemotherapy. In hormone-insensitive cancer, hormone therapy is ineffective, and chemotherapy becomes the treatment of choice.

Stage 4 breast cancer treatment is carried out until the very moment it stops being effective. The chances for recovery for stage 4 breast cancer is around 22%. It is possible to achieve stable remission in less than 10% of patients with stage 4 breast cancer.

Clinical trials

 

Clinical trials are designed for elaboration of the novel treatment options. The significance of clinical trials among stage 4 breast cancer treatment options specifically cannot be underrated. In some cases there's a need for an alternative therapy when conventional stage 4 breast cancer treatment options are insufficient.

A patient can be included in the clinical trials only after voluntary informed consent is obtained, as well as if the diagnosis meets the criteria for inclusion in clinical trials.

You can talk to your doctor about the benefits of participation in your case and ask about the available clinical trials for your diagnosis.

Best hospital for breast cancer treatment abroad

 

In choosing the best hospital for breast cancer treatment abroad several aspects must be considered, i.e.:

  • Certifications of hospitals (presence of certain certificates indicates that the breast cancer treatment in hospitals is conducted following the international protocols)
  • Availability of up-to-date equipment in hospitals
  • Experience of oncologists that work in hospitals (usually, hospitals have the profiles of doctors on their websites)
  • Availability of new treatment methods (leading foreign hospitals offer breast cancer treatment using immunotherapy, targeted therapy, or proton therapy)
  • Pricing policy of the hospitals (some hospitals provide additional services for more comfortable treatment, increasing the cost of treatment; also, due to taxes, cancer care in some hospitals can be more expensive)
  • Location of hospitals (relevant in certain cases)

Booking Health has already helped thousands of patients to find the best hospital for treatment abroad for their diagnosis. You can choose the best hospital for breast cancer treatment abroad among the most trustworthy specialized hospitals:

  1. University Hospital Tuebingen
  2. University Hospital Ulm
  3. University Hospital Frankfurt am Main
  4. Charite University Hospital Berlin
  5. University Hospital Muenster

Contact Booking Health for assistance in the selection of the best hospital for breast cancer treatment for you.

Prices for treatment abroad

 

The prices for treatment procedures are different in different countries. Prices in German hospitals are as follows:

  • The cost of treatment of breast cancer with chemotherapy starts at 6,470 EUR
  • The cost of treatment with radiotherapy starts at 13,800 EUR
  • The cost of treatment with radical mastectomy starts at 10,639 EUR

You can find more prices for medical procedures on the Booking Health website.

Why undergoing treatment with Booking Health?

 

With a cancer diagnosis, postponing the treatment isn’t an option. And the time you may spend organizing the treatment abroad can be used more efficiently.

Deciding to use the services of the medical tourism operator Booking Health, you save not only time but also your money, and more importantly, you get a guarantee of high quality of treatment abroad.

If you need any help with figuring out how this works, leave a request on the Booking Health website, and a medical advisor will contact you shortly.

Authors: Dr. Nadezhda IvanisovaDr. Farrukh Ahmed




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