About the disease
Clear cell renal carcinoma is a type of kidney cancer. It is called clear cell renal carcinoma because it forms in the cells lining, specifically in small tubules which are responsible for filtering waste and also for producing the urine. The waste is filtered from blood and, these tubules are helping the body to get rid of all unnecessary and harmful chemicals and elements. According to the National Cancer Institute, only in the USA approximately 58, 000 people had been diagnosed with clear cell renal carcinoma in 2010.
Most common age when clear cell renal carcinoma is diagnosed is over 55 years. This cancer is more common among male population. According to statistics, if clear cell renal carcinoma is diagnosed early in the beginning stages of its development, the prognosis is good and the patient usually recovers. However, if cancer spreads outside the kidney and affects other organs, prognosis can be fatal, that`s why it is important to get the diagnosis early.
Overall, clear cell renal carcinoma is the most common type of kidney cancer representing approximately 92% of all kidney cancer cases. Other relatively common type of kidney cancer is papillary carcinoma, which accounts for approximately 8% of kidney cancer cases.
Clear cell renal carcinoma can be latent for a long period of time without showing any symptoms. In some cases, it can be discovered already on the advanced stages, that`s why it is important to have regular check-ups and to pay attention if there is something wrong with the kidneys. The most common manifestation of clear cell renal carcinoma is blood in the urine which is observed in approximately 40% of all patients with this disease. Blood in the urine is never a normal process, that`s why one should pay attention to this symptom.
- Blood in the urine
- Flank pain
- A palpable mass in the abdominal area
- Bloating in the abdominal area
- Weight loss
- Frequent urination
- Night sweats
- High blood pressure
- During a general examination, the doctor will palpate the mass in the abdominal area to determine if it is hard or soft in consistency. The doctor will ask the person about their lifestyle, medical history and also about any recent changes in weight. The doctor will ask if there had been blood in the urine as well.
- An urinalysis can be used to examine the urine and rule out other causes of problems with kidneys.
- An MRI and CT scan can detect any abnormal changes and malformations in the kidney area.
- A biopsy of the kidney can be used to examine it under the microscope and determine if there are malignant cells that would indicate cancer. A biopsy can also determine the type of kidney cancer.
- Chemotherapy is used to kill the malignant cells with special drugs-agents aimed to destroy them.
- Tumor resection can also be used to resect the tumor and keep it from spreading further.
- Radiotherapy can be used to shrink the tumor and also prevent it from growing.