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Diagnostic and treatment of Parkinsons disease

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Cost for treatment

Parkinson Disease Diagnostics
 from  892
Diagnosis and conservative treatment of parkinsons disease
 from  3269
Diagnosis of Parkinson's disease before deep brain stimulation (DBS) and implanted of neurostimulator
 from  2082

Bundeswehr Academic Hospital Berlin

10/10
location_onGermany, Berlin

Department of Neurology

The Bundeswehr Academic Hospital Berlin is a modern medical facility that offers first-class medical care in the field of emergency care, traumatology, urology, internal medicine, surgery, neurosurgery, neurology, nuclear medicine and other focuses. The hospital has 15 specialized departments, medical teams of which guarantee th
Parkinson Disease Diagnostics
3256 help2856
Diagnosis and conservative treatment of parkinsons disease
8628 help7428
Diagnosis of Parkinson's disease before deep brain stimulation (DBS) and implanted of neurostimulator
9069 help8569

Beta Klinik Bonn

9.7/10
location_onGermany, Bonn

Department of Neurology and Epileptology

Beta Klinik is a modern hospital which consists of 30 specialized departments. The hospital is equipped with the state-of-the-art equipment of the university level. The operating rooms, an intensive care unit and the rehabilitation center correspond to the highest standards. It also concerns highly qualified physicians of the ho
Parkinson Disease Diagnostics
3268
Diagnosis and conservative treatment of parkinsons disease
10324
Diagnosis of Parkinson's disease before deep brain stimulation (DBS) and implanted of neurostimulator
7627

Memorial Bahcelievler Hospital Istanbul

9.2/10
location_onTurkey, Istanbul

Department of Neurology

The Memorial Bahçelievler Hospital Istanbul is an advanced multidisciplinary medical center that began its clinical practice in 2018. It is part of the world famous Memorial Healthcare Group. The hospital was designed in accordance with the very latest standards of modern architecture with the aim of providing top-class m
Parkinson Disease Diagnostics
1433
Diagnosis and conservative treatment of parkinsons disease
5384
Diagnosis of Parkinson's disease before deep brain stimulation (DBS) and implanted of neurostimulator
3677

University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of Neurology

The University Hospital Ulm started its activities 35 years ago and during this time it has become one of the most prestigious medical institutions in Europe. The hospital is famous for its numerous discoveries and the world-class achievements in medicine and pharmaceuticals. The medical facility has 29 specialized departments a
Parkinson Disease Diagnostics
3321
Diagnosis and conservative treatment of parkinsons disease
10943
Diagnosis of Parkinson's disease before deep brain stimulation (DBS) and implanted of neurostimulator
7822

Tel Aviv Sourasky Medical Center

9.9/10
location_onIsrael, Tel Aviv

Department of Neurology

The Tel Aviv Sourasky Medical Center is the second largest and one of the most advanced healthcare and research facilities in Israel. It began its work in 1961, but it is still popular among the local population and attracts thousands of international patients. The multidisciplinary medical center covers an area of ​​150,000 m&s
Parkinson Disease Diagnostics
2126
Diagnosis and conservative treatment of parkinsons disease
7652
Diagnosis of Parkinson's disease before deep brain stimulation (DBS) and implanted of neurostimulator
4981

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Department of Neurology

According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! The hospital is one of the largest and leading university medical complexes in Europe. The hospital in Germany provides modern diagnostics and treatment of patients, a
Parkinson Disease Diagnostics
4466
Diagnosis and conservative treatment of parkinsons disease
14576
Diagnosis of Parkinson's disease before deep brain stimulation (DBS) and implanted of neurostimulator
10373

Medipol Mega University Hospital Istanbul

8/10
location_onTurkey, Istanbul

Department of Neurology

The Medipol Mega University Hospital is the leading and the largest medical facility in Turkey where the patients can receive top-class medical services according to the international standards. Thanks to a highly qualified medical team, cutting-edge medical technology and a special atmosphere aimed at recovery, the hospital has
Parkinson Disease Diagnostics
1754 help1554
Diagnosis and conservative treatment of parkinsons disease
6106 help5306
Diagnosis of Parkinson's disease before deep brain stimulation (DBS) and implanted of neurostimulator
4026 help3526

Primus Super Speciality Hospital New Delhi

9/10
location_onIndia, New Delhi

Department of Adult and Pediatric Neurosurgery, Neurology

The Primus Super Speciality Hospital New Delhi is a modern medical facility, which is distinguished by extremely high quality and standards of medical service. The hospital is located in the heart of New Delhi, in the capital of India. During its design and construction, the most advanced medical technologies from around the wor
Parkinson Disease Diagnostics
928
Diagnosis and conservative treatment of parkinsons disease
3276
Diagnosis of Parkinson's disease before deep brain stimulation (DBS) and implanted of neurostimulator
2100

University Hospital of Ludwig Maximilian University of Munich

10/10
location_onGermany, Munich

Department of Neurology

According to the Focus magazine, the University Hospital of Ludwig Maximilian University of Munich is regularly ranked among the best medical institutions in Germany! The hospital is the largest multidisciplinary medical facility, as well as a leading research and training center in Germany and Europe. The hospital is proud of i
Parkinson Disease Diagnostics
3606
Diagnosis and conservative treatment of parkinsons disease
11376
Diagnosis of Parkinson's disease before deep brain stimulation (DBS) and implanted of neurostimulator
8058

University Hospital Muenster

9.8/10
location_onGermany, Muenster

Department of General Neurology

According to the Focus magazine, the University Hospital Muenster ranks among the top German hospitals! The hospital belongs to the most prestigious medical institutions in Germany. The hospital is distinguished by a high professionalism of its doctors, state-of-the-art technological equipment and the availability of the most ad
Parkinson Disease Diagnostics
3268
Diagnosis and conservative treatment of parkinsons disease
10256
Diagnosis of Parkinson's disease before deep brain stimulation (DBS) and implanted of neurostimulator
7555

University Hospital Frankfurt am Main

10/10
location_onGermany, Frankfurt am Main

Department of Neurology

According to the reputable Focus magazine, the University Hospital Frankfurt am Main ranks among the top German medical facilities! The hospital was founded in 1914 and today is a well-known German medical facility, which combines rich traditions and scientific innovations. A medical team of more than 6,500 employees cares about
Parkinson Disease Diagnostics
3201
Diagnosis and conservative treatment of parkinsons disease
10436
Diagnosis of Parkinson's disease before deep brain stimulation (DBS) and implanted of neurostimulator
7510

University Hospital Carl Gustav Carus Dresden

9.1/10
location_onGermany, Dresden

Department of Neurology

According to the prestigious Focus magazine, the University Hospital Carl Gustav Carus Dresden is among the top three hospitals in Germany! The hospital is the embodiment of the standards of modern high-quality medicine. Since the hospital positions itself as a maximum care medical facility, it represents all medical fields. The
Parkinson Disease Diagnostics
3952
Diagnosis and conservative treatment of parkinsons disease
13013
Diagnosis of Parkinson's disease before deep brain stimulation (DBS) and implanted of neurostimulator
9300

University Hospital Heidelberg

9.8/10
location_onGermany, Heidelberg

Department of Neurology

According to the Focus magazine, the University Hospital Heidelberg ranks among the top five hospitals in Germany! The hospital is one of the most advanced and reputable medical institutions not only in Germany, but throughout Europe. There are more than 43 specialized departments and 13 medical institutes, which cover all field
Parkinson Disease Diagnostics
0
Diagnosis and conservative treatment of parkinsons disease
0
Diagnosis of Parkinson's disease before deep brain stimulation (DBS) and implanted of neurostimulator
0

University Hospital RWTH Aachen

9.1/10
location_onGermany, Aachen

Department of Neurology

According to the prestigious Focus magazine, the University Hospital RWTH Aachen ranks among the top German hospitals! As a maximum care university medical facility, the hospital guarantees patients first-class medical services combined with a respectful and human attitude. The hospital integrates all the modern options for the
Parkinson Disease Diagnostics
3468
Diagnosis and conservative treatment of parkinsons disease
11301
Diagnosis of Parkinson's disease before deep brain stimulation (DBS) and implanted of neurostimulator
8194

University Hospital Bonn

9.2/10
location_onGermany, Bonn

Department of Neurology

According to the authoritative Focus magazine, the University Hospital Bonn ranks among the top ten medical facilities in Germany! The hospital was opened on January 1, 2001, although in fact it inherits the medical facility, which operated at the Faculty of Medicine of the University of Bonn. The hospital in Germany combin
Parkinson Disease Diagnostics
3485
Diagnosis and conservative treatment of parkinsons disease
11393
Diagnosis of Parkinson's disease before deep brain stimulation (DBS) and implanted of neurostimulator
8188

University Hospital Würzburg

9.2/10
location_onGermany, Würzburg

Department of Neurology

According to the Focus magazine in 2019, the University Hospital Würzburg ranks among the top national German hospitals! The hospital is one of the oldest medical facilities in Germany. The centuries-old traditions of first-class treatment are combined with the very latest achievements of modern evidence-based medicine and
Parkinson Disease Diagnostics
3308
Diagnosis and conservative treatment of parkinsons disease
10327
Diagnosis of Parkinson's disease before deep brain stimulation (DBS) and implanted of neurostimulator
7539

About the disease

Parkinson’s disease is a chronic, progressive brain disease, first described in the beginning of nineteenth century by the English doctor-physician John Parkinson. It is also known as a tremor disease. Patients with Parkinson’s disease often suffer from uncontrolled limb tremor, muscles stiffness, impaired joint coordination and problem with speech. These signs usually develop after age of 55, although there are cases of Parkinson’s disease under the age of 55 years.

Tremor develops as a result of damage or destruction of neurons located in the black substance of a brain and accumulation of alpha-synuclein inside them. In healthy brain these nerve cells produce neurotransmitter dopamine. The function of dopamine is to ensure the normal work of mesocortical (responsible for motivation and emotional reactions), mesolimbic (responsible for feelings of pleasure, reward and desire) and nigrostriatal pathway (responsible for motor activity). In Parkinson’s disease the reduced production of dopamine interferes with the normal transmission of nerve impulses.

Several medications taken for a long time at high doses can cause Parkinson’s disease. These includes drugs for treatment of certain mental disorders, as well as anti-nausea medications, such as metoclopramide. The antiepileptic valproic acid may also cause some of the most well-known symptoms of Parkinson's disease. Parkinson’s disease may also be caused by an infectious or traumatic brain injury.

Symptoms

  • Tremor of hands
  • Light finger shaking
  • Minor speech disorders
  • Devastating mood
  • Loss of vital strength
  • Insomnia

Parkinson’s disease is progressive, its symptoms aggravate and worsen over time. It eventually leads to disability and total loss of motion capacity.

Tremor often starts with a slight trembling of the fingers or of even individual fingertips. In some cases tremor is accompanied by uneven movement of middle finger and thumb which looks like a person is rolling invisible pills. These symptoms may appear with other disorders of nervous system, such as discoordination. Shaking is particularly evident during the "pill rolling syndrome" which occurs mostly when the patient is stressed and devastated about something. Although tremor of limbs and joints causes considerable further inconvenience, it does not end in a total loss of vital capacity. Many patients with tremor disease suffer only from a little shaking.

Diagnosis

  • There are no specific diagnostic tests for Parkinson’s disease. That is why doctor starts examination from medical history checking and excluding concomitant pathology of the brain. Then doctor proceeds to neurological examination, including cognitive tests.
  • Transcranial sonography is the ultrasound technique that allows to assess the state of dopamine-producing cells.
  • MRI allows to exclude not connected with Parkinson’s disease brain injuries that can also cause tremor.
  • PET-scan is the most informative examination, as it reflects the functional activity of the brain cells. PET-scan can reveal the earliest stages of the disease.

Treatment

The treatment program should be individualized for each patient. The rationally selected regimen will allow to achieve good results for a long time. 

  • Lifestyle modification. Aerobic exercises and balance training will improve ability to walk and somewhat reduce tremor.
  • Drugs intake. The most effective in patients with Parkinson’s disease medication is carbidopa-levodopa. It replaces deficiency of dopamine and restores normal work of nervous pathways. Dopamine agonists are also used. This type of drugs has different from the dopamine structure, but similar effects. Anticholinergics will help to cope with tremor, this is a symptomatic treatment.
  • Deep brain stimulation (DBS) with implanted neurostimulator is the modern treatment technique, which uses neurostimulator to send electrical impulses to specific areas in the brain responsible for movement. This procedure can improve tremor and other manifestations of dyskinesia.
  • Pallidotomy is a surgery during which a surgeon removes the overactive part of the brain, which lessens the tremor and eliminates rigidity.



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