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diagnostic: Chronic myelogenous leukemia (cml). Diagnostic

Chronic myeloid leukemia (CML) is malignant disease of the blood caused by structural changes in the 9th and 22nd pairs of granulocyte chromosomes. This genetic disorder is called "Philadelphia chromosome." According to statistics, people aged 30-50 years are the most susceptible to CML. The key to a successful fight against this pathology is early diagnosis.

Procedure

The survey begins with the oncologist’s advice. The physician clarifies complaints, collects the case history and conducts a clinical examination. If there is a suspicion for a pathology, the patient receives a referral for complete blood count and blood chemistry. Certain changes in the hemogram (increased number of white blood cells, decrease in red blood cells and platelets) are a basis for further diagnostics.

The optimum research program includes:

1. Lymphocyte immunophenotyping by flow cytometry. The tumor cells are exposed to antibodies. The resulting complexes are then detected using fluorescent labels. This technique allows not only to diagnose the disease, but also to determine its specific type. This analysis requires the patient’s blood taken from a vein.

2. Cytogenetic analysis by standard karyotyping. Blood elements are stained in a special way and examined under a microscope. The research task is to detect or rule out the chromosomal breakage associated with leukemia.

3. Cytogenetic study by fluorescent hybridization. This study is carried out for the sole purpose of establishing the presence of "Philadelphia chromosome," provoking the CML development. Short DNA sequences (probes) labeled with fluorophores are used for analysis. Interacting with them, the altered chromosomes 9 and 22 are stained red and green.

4. Abdomen ultrasound. The patients diagnosed with CML feature the change of the liver and spleen size.

5. CT scan or MRI of the whole body. Comprehensive scanning allows establishing the prevalence of tumor process (impairment of bones, lymph nodes, brain, and other internal organs).

6. Bone marrow aspiration biopsy (ilium wing punch biopsy). During the procedure, a sample of the bone marrow is taken from the patient. The material is sent for histological analysis by which the chronic myeloid leukemia is distinguished from chronic lymphoblastic leukemia.

Painful procedures are performed under local anesthesia or in a drug-induced sleep. The cost of medication is determined by the treatment intensity. The patient during treatment is under supervision of medical personnel.

According to the test findings, the physician establishes an accurate diagnosis and develops the further treatment tactics.

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Age: 15 years or older

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Luisenhospital

9.8/10 from 3 Votes

Department of Gastroenterology, Cardiology, Diabetology, Pulmonology and Oncology

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis #332361

The Department of Gastroenterology, Cardiology, Diabetology, Pulmonology and Oncology offers a wide spectrum of medical services ranging from gastroenterology (diseases of the stomach, intestines, pancreas and liver), cardiology (heart disease and circulatory disorders) and diabetes (diabetes m...


Duration: 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Aachen

University Hospital Bonn

9.2/10 from 150 Votes

Department of Oncology, Hematology, Rheumatology and Immunoncology

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis #87869

The key objective of the Department of Internal Medicine III is to create and offer optimal treatments for internal diseases on inpatient, partially inpatient and outpatient basis.


Duration: 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Bonn
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University Hospital Cologne

9.8/10 from 82 Votes

Department of Internal Medicine I: oncology, hematology, clinical infectiology, clinical immunology, hemostasis, intensive care

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis #165669

The Department of Internal Medicine I deals with the treatment of various internal diseases. The department specializes in the following medical focuses: oncology, hematology, clinical infectology, clinical immunology, hemostasis, intensive care.


Duration: 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Cologne
certificate

University Hospital Frankfurt

9.5/10 from 97 Votes

Department of Hematology, Oncology, Hemostaseology, Rheumatology and Infectiology

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis #76481

The Department of Hematology, Oncology, Hemostaseology, Rheumatology and Infectiology specializes in the treatment of all diseases of the hematopoietic system and solid tumors.


Duration: 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Frankfurt am Main

Charite University Hospital Berlin

9/10 from 95 Votes

Charité Comprehensive Cancer Center

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis #229163

The Charite Comprehensive Cancer Center integrates all departments and units dealing with cancer treatment. The center offers patients the most advanced comprehensive cancer treatment.


Duration: 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Berlin
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Academic Hospital Schwabing

8.5/10 from 7 Votes

Department of Hematology, Oncology, Immunology, Palliative Medicine, Infectiology and Tropical Medicine

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis #177529

The Department of Hematology, Oncology, Immunology, Palliative Medicine, Infectious Diseases and Tropical Medicine in Schwabing treats all benign blood diseases, disorders of the immune and coagulation system, all forms of blood cancer, and the most of cancers.


Duration: 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Munich

Academic Hospital Nordwest

9.5/10 from 24 Votes

Department of Oncology and Hematology

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis #35007

The Department of Oncology and Hematology at the Hospital Nordwest is a medical institution, which deals with the diagnosis, treatment and follow-up care of patients with benign and malignant tumors of the hematopoietic system, as well as all kinds of cancer.


Duration: 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Frankfurt am Main
certificate

University Hospital RWTH Aachen

8.7/10 from 41 Votes

Department of Oncology, Hematology and Stem Cell Transplant

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis #105711

The Department of Oncology, Hematology and Stem Cell Transplant provides patient care on both inpatient and outpatient basis. The focuses of the inpatient treatment are acute leukemia and high-dose chemotherapy followed by autologous blood stem cell transplantation.


Duration: 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Aachen
certificate

Alfried Krupp Hospital in Essen-Ruettenscheid

7.4/10 from 42 Votes

Department of Internal Medicine I (Gastroenterology, Hematology, Onkology, Cardiology, Pulmology, Sport Medicine)

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis #216635

The main treatment areas of the Department of Internal Medicine I, headed by Prof. Dr. med. Thomas Budde, are invasive and non-invasive cardiac diagnostics and therapy of all cardiac diseases.


Duration: 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Essen

University Hospital Düsseldorf

9.9/10 from 71 Votes

Department of Hematology, Oncology and Clinical Immunology

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis #166227

The Department of Hematology, Oncology and Clinical Immunology at the University Hospital Dusseldorf provides treatment of patients with blood diseases, cancer and immune system diseases. The Department focuses on the treatment of malignant diseases of  blood, bone marrow and lymph nodes.


Duration: 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Duesseldorf

Tel Aviv Sourasky Medical Center

9.9/10 from 23 Votes

Department of Hematology

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis #331117

The Department of Hematology at the Tel Aviv Sourasky Medical Center provides expert care for patients with a variety of blood disorders, including malignant hematological diseases.


Duration: 6 days
Type of Treatment: Outpatient
location_onCountry: Israel
location_searchingCity: Tel Aviv

Hannover Medical School

9.8/10 from 43 Votes

Department of Hematology, Hemostaseology, Oncology and Stem Cell Transplantation

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis #247027

The Department of Hematology, Hemostasiology, Oncology and Stem Cell Transplantation at the Hannover Medical School specializes in diagnosis and treatment of the entire range of malignant tumors, benign hematological diseases and blood coagulation disorders.


Duration: 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Hannover
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Academic Hospital Neuperlach

9.8/10 from 11 Votes

Department of Hematology and Oncology

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis #145023

The department of hematology and oncology diagnosed and treated malignant tumors. The therapeutic spectrum includes all medicamentous treating methodes including chemotherapy, antibody, immune and hormone therapy. Cancer patients benefit from interdisciplinary treatment.


Duration: 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Munich

District Hospital Waldbröl Oberberg

9.7/10 from 23 Votes

Department of Hematology, Oncology, Palliative Medicine and Sleep Laboratory

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis #286494

The Department of Hematology, Oncology, Palliative Medicine, Pneumology and Somnology at the District Hospital of Waldbröl (Medical Department III) has 30 beds. A competent treatment is provided by three medical specialists in the field of hematology and oncology and a professional anesthesiologist.


Duration: 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Waldbrоl

University Hospital Halle (Saale)

9.6/10 from 78 Votes

Department of Hematology and Oncology (Department of Internal Medicine IV)

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis #251067

The Department of Internal Medicine IV (Hematology and Oncology) covers the whole range of hematology and oncology. This includes prevention, diagnosis, therapy and post-operative care for cancer of all organs and blood.


Duration: 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Halle
certificate

University Hospital Essen

9.6/10 from 23 Votes

Department of Hematology

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis #290698

The Department of Hematology at the Essen University Hospital is the largest center for blood diseases in the Ruhr Area.


Duration: 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Essen




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