diagnostic:
Chronic myelogenous leukemia (cml). Diagnostic abroad

Chronic myeloid leukemia (CML) is malignant disease of the blood caused by structural changes in the 9th and 22nd pairs of granulocyte chromosomes. This genetic disorder is called "Philadelphia chromosome." According to statistics, people aged 30-50 years are the most susceptible to CML. The key to a successful fight against this pathology is early diagnosis.

Procedure

The survey begins with the oncologist’s advice. The physician clarifies complaints, collects the case history and conducts a clinical examination. If there is a suspicion for a pathology, the patient receives a referral for complete blood count and blood chemistry. Certain changes in the hemogram (increased number of white blood cells, decrease in red blood cells and platelets) are a basis for further diagnostics.

The optimum research program includes:

1. Lymphocyte immunophenotyping by flow cytometry. The tumor cells are exposed to antibodies. The resulting complexes are then detected using fluorescent labels. This technique allows not only to diagnose the disease, but also to determine its specific type. This analysis requires the patient’s blood taken from a vein.

2. Cytogenetic analysis by standard karyotyping. Blood elements are stained in a special way and examined under a microscope. The research task is to detect or rule out the chromosomal breakage associated with leukemia.

3. Cytogenetic study by fluorescent hybridization. This study is carried out for the sole purpose of establishing the presence of "Philadelphia chromosome," provoking the CML development. Short DNA sequences (probes) labeled with fluorophores are used for analysis. Interacting with them, the altered chromosomes 9 and 22 are stained red and green.

4. Abdomen ultrasound. The patients diagnosed with CML feature the change of the liver and spleen size.

5. CT scan or MRI of the whole body. Comprehensive scanning allows establishing the prevalence of tumor process (impairment of bones, lymph nodes, brain, and other internal organs).

6. Bone marrow aspiration biopsy (ilium wing punch biopsy). During the procedure, a sample of the bone marrow is taken from the patient. The material is sent for histological analysis by which the chronic myeloid leukemia is distinguished from chronic lymphoblastic leukemia.

Painful procedures are performed under local anesthesia or in a drug-induced sleep. The cost of medication is determined by the treatment intensity. The patient during treatment is under supervision of medical personnel.

According to the test findings, the physician establishes an accurate diagnosis and develops the further treatment tactics.

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University Hospital Bonn

8.6/10 from 150 Votes

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis

The key objective of the Department of Internal Medicine III is to create and offer optimal treatments for internal diseases on inpatient, partially inpatient and outpatient basis.


Duration 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Bonn

Price 6541.00

University Hospital Cologne

8.7/10 from 82 Votes

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis

The Department I for Internal Medicine of the University Hospital Cologne deals with the treatment of patients with various internal diseases. This includes in particular the following fields: Oncology, Hematology, Clinical infectology, Clinical immunology, Hemostasis, Intensive care.


Duration 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Cologne

Price 6645.00

University Hospital Frankfurt

7.5/10 from 97 Votes

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis

The Department of Hematology, Oncology, Hemostasis, Rheumatology and Infectology at the University Hospital Frankfurt specializes in the treatment of all diseases of the hymatopoietic system and solid tumors.


Duration 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Frankfurt am Main

Price 7741.00

Charite University Hospital Berlin

9/10 from 95 Votes

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis

The Charité Comprehensive Cancer Center integrates the clinical and research activities for all Charité departments and institutes dealing with Cancer. The director of the Charité Comprehensive Cancer Center is Prof. Dr. med. Ulrich Keilholz.


Duration 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Berlin

Price 9321.00

University Hospital Heidelberg

9/10 from 57 Votes

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis

The Department of Hematology, Oncology and Rheumatology at the Heidelberg University Hospital makes every effort to provide medical care of the highest quality to the patients with oncologic and rheumatologic diseases.


Duration 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Heidelberg

Krankenhaus Nordwest

9.5/10 from 24 Votes

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis

Department of Oncology and Hematology of Krankenhaus Nordwest offers a wide range of medical services, including diagnosis, therapy and treatment of oncological diseases or diseases closely associated with the circulatory system.


Duration 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Frankfurt am Main

Price 5797.00

Städtisches Klinikum Schwabing

8.5/10 from 7 Votes

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis

The Department of Hematology, Oncology, Immunology, Palliative Medicine, Infectious Diseases and Tropical Medicine in Schwabing treats all benign blood diseases, disorders of the immune and coagulation system, all forms of blood cancer, and the most of cancers.


Duration 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Munich

Price 6084.00

RWTH University Hospital Aachen

8.7/10 from 41 Votes

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis

The Department of Oncology, Hematology and Stem Cell Transplant provides patient care on both inpatient and outpatient basis. The focuses of the inpatient treatment are acute leukemia and high-dose chemotherapy followed by autologous blood stem cell transplantation.


Duration 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Aachen

Price 6014.00

Alfried Krupp Hospital in Essen-Ruettenscheid

9.9/10 from 42 Votes

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis

The main treatment areas of the Department of Internal Medicine I, headed by Prof. Dr. med. Thomas Budde, are invasive and non-invasive cardiac diagnostics and therapy of all cardiac diseases.


Duration 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Essen

Price 5320.00

University Hospital Dusseldorf

9.9/10 from 71 Votes

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis

The Department of Hematology, Oncology and Clinical Immunology at the University Hospital Dusseldorf provides treatment of patients with blood diseases, cancer and immune system diseases. The Department focuses on the treatment of malignant diseases of  blood, bone marrow and lymph nodes. .


Duration 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Duesseldorf

Price 7693.00

Hannover Medical School, MHH

9.8/10 from 43 Votes

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis

The clinic of hematology, hemostasis, oncology and stem cell transplantation is a leading therapeutic clinic of the Medical Institute of Hannover for patients with solid tumor and systemic diseases, with other partially benign diseases of the hematopoietic system, as well as bleeding disorders.


Duration 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Hannover

Price 6306.00

Städtisches Klinikum Neuperlach

9.8/10 from 11 Votes

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis

The department of hematology and oncology diagnosed and treated malignant tumors. The therapeutic spectrum includes all medicamentous treating methodes including chemotherapy, antibody, immune and hormone therapy. Cancer patients benefit from interdisciplinary treatment.


Duration 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Munich

Price 5775.00

Gummersbach District Hospital of the Klinikum Oberberg

9.6/10 from 23 Votes

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis

The Department of Internal Medicine II at the Klinikum Oberberg in Gummersbach focuses on diagnosis and treatment of oncological and hematological diseases.


Duration 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Gummersbach

Price 5545.00

University Hospital Halle (Saale)

9.5/10 from 78 Votes

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis

The Department of Internal Medicine IV (Hematology and Oncology) covers the whole range of hematology and oncology. This includes prevention, diagnosis, therapy and post-operative care for cancer of all organs and blood.


Duration 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Halle

Price 6328.00

UKGM Gießen

9.5/10 from 35 Votes

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis

The department of internal medicine IV and V includes general internal medicine and a number of priority areas of this subject. The clinic offers a wide range of newest innovative treatments especially in the fields of medical oncology, hematology and palliative care.


Duration 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Giessen

Price 5957.00

University Hospital Hamburg-Eppendorf

9.2/10 from 92 Votes

Chronic Myelogenous (Myeloid) Leukemia (CML) Diagnosis

The Medical Department II at the University Medical Center Hamburg-Eppendorf specializes in the treatment of patients with cancer of the internal organs and hematopoietic system. There is provided the whole range of treatments for these diseases.


Duration 6 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Hamburg

Price 9113.00