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Brachytherapy for Prostate Cancer treatment in the Best Hospitals in the World

University Hospital of Ludwig Maximilian University of Munich

10/10
location_onGermany, Munich

Department of Adult and Pediatric Urology

According to the Focus magazine, the Department of Adult and Pediatric Urology ranks among the top German departments specializing in prostate cancer treatment! The department offers the full range of diagnostics and treatment of urological diseases in men and boys. The department employs comprehensively trained, experienced doctors, who use in their practice all the advanced medical achievements. Each patient is provided with an individual approach to therapy with due consideration of specific needs and wishes.

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book Insurance against increased costs in case of complications with a cover of 200,000 €

Marien Hospital Marl

9.8/10
location_onGermany, Marl

Department of Adult and Pediatric Urology

The Department of Adult and Pediatric Urology offers the full range of diagnostics and treatment of diseases of the genitourinary system in men and boys. The department has 62 beds for inpatient treatment. The therapeutic options include both conservative and surgical techniques. Many operations are performed using the innovative da Vinci surgical system. The key focus of the department is cancer surgery in malignant diseases of the prostate gland, bladder, kidneys and testicles. Also, the department specializes in the treatment of urinary incontinence and pediatric urological pathologies.

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Helios Hospital Berlin-Buch

9.7/10
location_onGermany, Berlin

Department of Urology

The Department of Urology offers the full range of diagnostics and treatment in this ​​medical field. The department's doctors have excellent qualifications in the treatment of diseases of the kidneys, urinary tract and reproductive organs in men. Of particular interest is the treatment of malignant urological neoplasms, which include prostate cancer, testicular cancer, kidney and bladder cancer. The department has in its arsenal many effective conservative and surgical treatment techniques, which can fully restore men's health.

University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of Adult and Pediatric Urology

According to the Focus magazine, the Department of Adult and Pediatric Urology ranks among the top medical institutions in Germany for prostate cancer treatment! The department offers the full range of high-precision diagnostics and effective treatment of diseases of the urogenital system, genitals in men and boys. It treats about 3,000 inpatients and 9,000 outpatients with the clinical cases of varying severity every year.

Urology Hospital Munich-Planegg Munich

10/10
location_onGermany, Munich

Department of Adult and Pediatric Urology

The Department of Adult and Pediatric Urology offers the full service range for the diagnostics and treatment of urological diseases in men and children, as well as urogynecological problems in women. One of the department's priorities is the restoration of potency in men. According to international ratings, this is the best hospital in Europe where a team of urologists effectively treats erectile dysfunction. The department has all modern techniques for the treatment of pathologies of genitourinary tract, while the rich practical experience of doctors allows them to select the best treatment option for each patient. Another department's key focus is the treatment of benign and malignant diseases of the prostate gland.

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Department of Adult and Pediatric Urology

According to the Focus magazine, the Department of Adult and Pediatric Urology ranks among the top German medical facilities specializing in prostate cancer treatment! The department offers all types of modern diagnostic and therapeutic services for patients with urologic diseases. Of particular interest is the treatment of urogenital tumors in men and urogynecological diseases. The department also specializes in kidney transplantation, which is carried out within the specialized center. This center is the largest in Germany and Europe and annually demonstrates high treatment success rates. In addition, the department's competence covers the treatment of urological problems in boys of all age groups.

University Hospital Heidelberg

9.8/10
location_onGermany, Heidelberg

Department of Adult and Pediatric Urology

According to the Focus magazine, the Department of Adult and Pediatric Urology ranks among the top German departments specializing in prostate cancer treatment! The department offers the full range of diagnostics and treatment of the urinary system in men and boys. The department has a long history, rich traditions, and is also a recognized center of excellence in the treatment of all urological diseases. The department specializes in the treatment of malignant urological diseases, reconstructive surgery, pediatric urology, treatment of urinary tract dysfunction and kidney stone disease.

University Hospital Frankfurt am Main

10/10
location_onGermany, Frankfurt am Main

Department of Urology

According to the Focus magazine, the Department of Urology ranks among the top German medical institutions specializing in prostate cancer treatment! The department offers the full range of high-precision diagnostic studies and effective therapeutic options for men with diseases of the genitourinary system. The doctors of the department specialize in the treatment of prostate cancer, benign prostatic hyperplasia, kidney, testicular cancers, urolithiasis, erectile dysfunction and urinary incontinence. There are also excellent qualifications in the field of reconstructive urology.

University Hospital Jena

8.9/10
location_onGermany, Jena

Department of Adult and Pediatric Urology

According to the Focus magazine, the Department of Adult and Pediatric Urology ranks among the top German medical facilities specializing in prostate cancer treatment! The department offers the full range of advanced methods of diagnostics and treatment of all genitourinary system diseases, including in children. Of particular interest is the treatment of patients with urinary tract and kidney tumors, kidney stone disease, prostate diseases, treatment of urinary incontinence, andrologic disorders and urological problems in young patients. Since 2010, the department has been certified as the Prostate Cancer Center (certified by the German Cancer Society, recertified in 2016).

University Hospital Erlangen

9.1/10
location_onGermany, Erlangen

Department of Adult and Pediatric Urology, Andrology

According to the Focus magazine, the Department of Adult and Pediatric Urology, Andrology ranks among the best departments in Germany specializing in prostate cancer treatment! The department offers the full range of diagnostic and therapeutic services in the fields of its expertise. The department's medical team specializes in the treatment of diseases of the urinary tract in women and men, as well as in the treatment of pathologies of the reproductive system in adult men and children, andrological diseases in men. The primary focus of the clinical practice of the department's doctors is medical care for patients with kidney, bladder, ureteral, urethral, prostate, testicular and penile cancers. The department's specialists keep pace with medical innovations, so most surgical interventions are performed using sparing laparoscopic techniques that do not require large incisions in the skin and soft tissues. To treat prostate cancer, doctors successfully use robot-assisted prostatectomy with the da Vinci surgical system. This intervention has many advantages over classical surgery and is available only in the best hospitals in the world. In addition, the department's doctors demonstrate excellent results in the treatment of kidney stone disease, urinary incontinence and pelvic organ prolapse. A specially trained team of doctors has been formed for the treatment of urological pathologies in children. Of particular interest is the correction of congenital genitourinary anomalies in young patients.

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of Urology

According to the Focus magazine, the Department of Urology ranks among the top medical institutions in Germany specializing in prostate cancer treatment! The department offers the full range of diagnostics and treatment of urinary tract diseases in men. Of particular interest are kidney transplantation, treatment of benign and malignant urologic diseases. The department has become one of the pioneers in the field of minimally invasive robot-assisted surgery (da Vinci), thanks to which it has exceptional experience in this area. In addition, the department became the second medical facility in Germany, which performed kidney transplantation using a da Vinci robotic system.

University Hospital Hamburg-Eppendorf

9.2/10
location_onGermany, Hamburg

Department of Adult and Pediatric Urology

According to the Focus magazine, the Department of Adult and Pediatric Urology ranks among the top German medical facilities specializing in prostate cancer treatment! The department has all the diagnostic and therapeutic options to provide first-class medical care for patients with diseases of the genitourinary system. The priority focus is reconstructive urology, in particular, the whole range of urethral surgery, procedures for the treatment of urinary incontinence (including artificial sphincter implantation, sling procedures), as well as penile surgery for congenital or acquired malformations, prosthetics in case of erectile dysfunction.

University Hospital Würzburg

9.2/10
location_onGermany, Würzburg

Department of Adult and Pediatric Urology

The Department of Adult and Pediatric Urology offers the diagnostics and treatment of all diseases of the urinary system organs (kidneys, ureters, bladder, urethra, etc.), as well as of the male reproductive organs in adults and children. The department specializes in the surgical and drug treatment of oncological diseases, correction of complex malformations, and plastic reconstructive urology. The department is the certified Prostate Cancer Centre.

University Hospital Rechts der Isar Munich

9.8/10
location_onGermany, Munich

Department of Adult and Pediatric Urology

The Department of Adult and Pediatric Urology provides high-precision diagnostics and effective treatment of the full range of diseases of the kidneys, urinary tract, bladder, prostate, testicles and their appendages, vas deferens and penis. The treatment of urologic cancers is of particular interest. The focus of pediatric urologists is on young patients with congenital and acquired malformations of the genitourinary system. The department has its in-house advanced operating rooms, an X-ray unit, and two stations with 57 beds. The high quality of medical care is confirmed by many prestigious certificates, including the DEKRA certificate and the certificate of the European Board of Urology. As one of the best urologic facilities in Germany and a leading urology clinic in Munich, the department has been offering patients the daVinci robot-assisted surgery since 2009, which has many advantages for patients: minimal pain, speedy recovery, the highest level of precision compared to conventional surgical interventions.

University Hospital RWTH Aachen

8.7/10
location_onGermany, Aachen

Department of Adult and Pediatric Urology

According to the Focus magazine, the Department of Adult and Pediatric Urology ranks among the top German medical facilities specializing in prostate cancer treatment! The department offers services for the diagnostics and treatment of diseases of the kidneys, urinary tract and pathologies of the reproductive organs in men. The therapeutic options are complemented by the treatment of urological problems in children. The department's doctors focus on the patients with oncopathologies (prostate cancer, renal cell cancer, bladder cancer, testicular cancer). Of particular interest is minimally invasive therapy of stones in the kidneys, ureters and bladder. The doctors have in their arsenal conventional and the very latest conservative, drug and surgical therapies, which allow them to achieve the best result in clinical cases of varying severity.

University Hospital Duesseldorf

9.5/10
location_onGermany, Duesseldorf

Department of Adult and Pediatric Urology

According to the Focus magazine, the Department of Adult and Pediatric Urology ranks among the top German departments specializing in prostate cancer treatment! The department offers the widest range of modern diagnostic and therapeutic methods for accurate detection and treatment of diseases of the genitourinary system in men and boys. The priority focus of the department is the treatment of prostate cancer (certification of the German Cancer Society).

Brachytherapy of the prostate gland is the internal radiation therapy of the prostate. This type of prostate cancer treatment is the minimally invasive radiation therapy of prostate cancer.

Brachytherapy for prostate cancer

Brachytherapy is a type of radiation therapy (radiotherapy) in which a radioactive source is placed directly into or next to prostate cancer locus. There are two main types of brachytherapy: the low dose rate (LDR) and the high dose rate (HDR) radiation therapy. The dose rate refers to the speed at which the radiation dose is delivered, not the actual dose itself. This kind of radiation therapy may not be available in all hospitals and is not suitable for all prostate cancers.

The medical treatment method of brachytherapy is based on the introduction of I-125 isotope microcapsules into the prostate tissue. The location of the grains in the tissue of the prostate gland delivers the required dose of radiation inside the organ and minimizes the irradiation of nearby organs and tissues. It is carried out using a computer planning system. To carry out computer planning, accurate knowledge of the volume and configuration of the prostate gland is required, for which the so-called volume study is performed.

Brachytherapy in the medical treatment of patients with localized prostate cancer is comparable in effectiveness to radical prostatectomy and external beam radiation therapy. This method of radiation therapy treatment is characterized by a small number of complications, a short stay in the hospital, and quicker rehabilitation of patients after the intervention.

Indications for brachytherapy for prostate cancer

The most important point that determines the results of brachytherapy largely is the correct selection of eligible patients. The selection is based on the assessment of clinical and laboratory parameters, data of the digital rectal examination, rectal ultrasound scanning with an accurate determination of the volume of the prostate gland. In some cases, when the extracapsular spread is confirmed, external radiation therapy is recommended, with a possible combination with brachytherapy at the first stage.

Indications for the procedure include:

  • Histologically confirmed adenocarcinoma of the prostate
  • Clinical stage T1-T2, absence of clinical signs of damage to seminal vesicles and regional lymph nodes, absence of metastases
  • Life expectancy over 10 years
  • Prostate volume less than 50 cc
  • PSA blood level <20 ng/ml
  • Maximum flow of urination is more than 10 ml per second

Brachytherapy shows excellent long-term results in the medical treatment of patients with resection of the prostate.

Contraindications include:

1.    Severe obstruction and the presence of residual urine of more than 100 ml

2.    Acute prostatitis and other infectious and inflammatory diseases of the genitourinary system

Special cases of prostate cancer

Age is not a contraindication to prostate cancer radiation therapy treatment. It is necessary to assess the general health condition, the patient's desire, etc. If the PSA blood level is more than 20 ng/ml or the Gleason score is more than 6 points, it is necessary to make an individual decision for each patient. Prostate cancer treatments in this category require individual approach.

In some cases, the anatomical structure of the pelvis is a serious obstacle to performing brachytherapy in prostate cancer. To identify this condition, the tomography of the small pelvis is performed, in which the individual location of the prostate gland and the pubic arch is assessed.

Types of brachytherapy for prostate cancer treatment

There are two main types of brachytherapy for prostate cancer.

LDR brachytherapy is a radiation therapy that involves the insertion of permanent radioactive sources directly into the prostate. These sources emit localized radiation to the entire prostate to destroy the cancer cells. The action of radiation is limited to the prostate and only a few millimeters around it. LDR brachytherapy is generally a radiation therapy treatment for men with prostate cancer, that is completely limited to the prostate gland borders. Placement of permanent radioactive sources requires a procedure under anesthesia that typically takes an hour or two. This prostate cancer treatment may take one or two days.

HDR brachytherapy is a radiation therapy that also involves radioactive material placing directly into the prostate. Unlike LDR, the placement of the material is temporary and shorter – usually it takes a day or two at a time. The radiation therapy takes place at a hospital but may require a longer stay compared to the LDR brachytherapy. It is often performed in combination with external beam radiation therapy for locally advanced disease.

How is the brachytherapy carried out?

Brachytherapy of the prostate is performed under general anesthesia or anesthesia in which the lower body is numbed. Anesthesia lasts 2-3 hours. During the radiation therapy procedure, the patient's legs are spread apart, and a bladder catheter is inserted.

After disinfection of the perineum, a probe is inserted into the anus, the images from which are projected onto a screen, thus the prostate gland is visualized. After imaging the prostate, the specialist begins to insert hollow needles into the prostate gland. The number of needles depends on the size of the prostate and varies from 15 to 30 pieces.

Through hollow needles, radioactive nuclei are injected into the prostate, which either remain there forever or are removed after a certain time. Depending on the size and shape of the prostate, from 1 to 6 radioactive nuclei are injected through the needle. Thus, during prostate brachytherapy, a total of 40-120 nuclei are injected into the gland.

The brachytherapy procedure takes approximately 1.5 hours. After the radiation therapy, the patient stays in the clinic for at least 24 hours, in a specially equipped room. The next morning after the radiation therapy, if the patient does not experience problems with urination, the catheter is removed and the patient is discharged from the clinic.

Radioactive nuclei in the prostate gland lose 50% of their charge within the first 2 months after brachytherapy. Although the dose of radiation outside the man's body is minimal, it is recommended to avoid frequent and long-term contact with children and pregnant women during the first time after therapy.

Sexual intercourse after brachytherapy is permitted, but the using a condom is recommended, as one or more radioactive nuclei can be ejected during orgasm. Also, nuclei can be thrown out during urination, therefore, for the first time after brachytherapy, it is recommended to urinate through a strainer, and in case of ejection of nuclei, collect them in a container specially issued to the patient.

Side effects of brachytherapy

During the first days after prostate brachytherapy, wounds may form in the area of punctures in the perineum. This will go away by itself and shouldn't be too worrisome. Also, in the first days after brachytherapy, blood clots may be present in the urine. In this case, it’s recommended to drink more water so that the blood quickly flows out naturally.

Burning sensation during urination and a frequent urge to urinate are more common, especially during the first weeks after undergoing therapy. These side effects occur most often in patients with large prostates and in patients who have already had urinary problems.

Sometimes a few days after brachytherapy a natural urine drainage is not possible. In such cases, a catheter must be inserted. There may also be problems with bowel movement. Side effects usually go away in a few weeks.

Urinary incontinence after brachytherapy is rare. Unfortunately, erection problems are more common side effects. According to statistics, 30% of men after a course of brachytherapy have problems with erection and orgasm.

You should call your doctor right away if you:

  • Have increasing pain around the perineum (the area between your anus and the base of your scrotum) that is not relieved with painkillers. There may be only a mild pain in your perineum after the seed implantation, and it should get better each day.
  • Have increasing swelling in your scrotum. There may be only a mild swelling after the seed implantation, and it should get better each day.
  • Are not able to urinate (pee).
  • Have any questions or concerns about how you are healing.

If you have any of these signs, talk to your doctor or health care team. There are medicines and medical treatments that can help you feel better. You should talk to your doctor or health care team about any side effects you may have during or after your radiation therapy. Your health care team can help treat these problems.

The cost of brachytherapy

With Booking Health services, you can book brachytherapy for prostate cancer at an affordable price. The cost of the procedure varies in different countries. We can arrange a trip for radiation therapy at a fair price. The cost of brachytherapy for prostate cancer goes as follows:

  • Germany – from 18,000 EUR
  • Turkey – from 12,000 EUR
  • India – from 10,100 EUR

Where can I undergo brachytherapy for prostate cancer treatment abroad?

Among foreign hospitals, the best success rates in brachytherapy for prostate cancer treatment are demonstrated by:

1.    University Hospital of Ludwig Maximillian University of Munich, Department of Adult and Pediatric Urology. The department ranks among the TOP German departments specializing in prostate cancer treatment. It is certified as the Prostate Cancer Center according to the standards of the German Cancer Society. This fact confirms the credibility of the department in the field and the high success rates in prostate cancer treatment.

2.    Medipol Mega University Hospital Istanbul, Department of Adult and Pediatric Urology. The department offers a full range of diagnostics and treatment of genitourinary diseases in boys and men. Particular attention is paid to the surgical treatment of prostate cancer.

3.    University Hospital Ulm, Department of Adult and Pediatric Urology. The department ranks among the TOP German medical facilities specializing in prostate cancer treatment. The department is also certified by the German Cancer Society, therefore all the therapeutic interventions correspond to strict national and international standards.

How can I undergo brachytherapy treatment abroad?

The self-organization of radiation therapy treatment abroad can be overwhelming. It requires specific knowledge and experience in medical tourism. It is safer, easier, and less stressful to shift some responsibility onto a medical tourism agency.

Booking Health is the largest and most transparent medical tourism agency in the world. Medical treatment abroad is arranged due to the direct cooperation with leading foreign hospitals.

Booking Health provides the following services:

  • Selection of radiation therapy program and medical facility
  • Communication with the clinic
  • Providing the patient with the favorable overall cost of radiation therapy procedures
  • Translation of medical documents
  • Help in applying for a visa for the patient and accompanying person
  • Flight and accommodation booking
  • Interpreting services

To undergo prostate cancer treatment abroad for a reasonable price, please leave a request on our website. The medical tourism manager will contact you within a few hours.




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