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St. Vincentius Clinic Karlsruhe

9.8/10 from23 Votes

The St. Vincentius Clinic is the largest multidisciplinary medical institution and academiс hospital of the Albert Ludwig University of Freiburg. Treatment and diagnosis of patients is conducted by doctors with a scientific degree. They are introducing the latest progressive techniques.

Acute Lymphoblastic Leukemia (ALL) Diagnosis
14215
Consolidation treatment for acute lymphoblastic leukemia (ALL)
66340
High-intensity induction chemotherapy 1 block) of acute lymphoblastic leukemia (ALL)
39725
location_onCountry: Germany
location_searchingCity: Karlsruhe

Charite University Hospital Berlin

9/10 from95 Votes

Being the medical school for both Humboldt University and Free University of Berlin and having a long experience, the Charite Hospital has gained wide recognition. It is regarded as one of the most research-intensive medical facilities in Germany and the largest university medical center in Europe.

Acute Lymphoblastic Leukemia (ALL) Diagnosis
14081
Allogeneic bone marrow transplantation (stem cell transplant) in acute lymphoblastic leukemia (ALL)
239811
Consolidation treatment for acute lymphoblastic leukemia (ALL)
66714
location_onCountry: Germany
location_searchingCity: Berlin
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University Hospital Rechts der Isar of the Munich Technical University

10/10 from70 Votes

The Rechts der Isar Hospital is the University Hospital of the Technical University of Munich. There is intensive cooperation between the research facilities of the TU and the hospital in numbers of areas.

Acute Lymphoblastic Leukemia (ALL) Diagnosis
15810
Allogeneic bone marrow transplantation (stem cell transplant) in acute lymphoblastic leukemia (ALL)
260016
Consolidation treatment for acute lymphoblastic leukemia (ALL)
76110
location_onCountry: Germany
location_searchingCity: Munich
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Vivantes Neukölln Hospital Berlin

10/10 from23 Votes

The Vivantes Neukölln Hospital is the maximum care hospital and one of the largest healthcare facilities in Berlin.   There are more than 20 specialized departments and centers, including pediatric departments. In total, the hospital has 1,200 beds.

Acute Lymphoblastic Leukemia (ALL) Diagnosis
18077
Consolidation treatment for acute lymphoblastic leukemia (ALL)
86651
High-intensity induction chemotherapy 1 block) of acute lymphoblastic leukemia (ALL)
51287
location_onCountry: Germany
location_searchingCity: Berlin

Academic Hospital Neuperlach Munich

9.8/10 from11 Votes

The Neuperlach Clinic is a modern medical facility with a high level of service. The clinic has high-tech modern equipment, making it one of the best hospitals not only in Germany but also in Europe. There are comfortable single and double rooms with shower and toilet, TV, telephone and radio.

Acute Lymphoblastic Leukemia (ALL) Diagnosis
14193
Consolidation treatment for acute lymphoblastic leukemia (ALL)
66505
High-intensity induction chemotherapy 1 block) of acute lymphoblastic leukemia (ALL)
39707
location_onCountry: Germany
location_searchingCity: Munich

University Hospital Frankfurt am Main

10/10 from97 Votes

The University Hospital Frankfurt is part of the Johann Wolfgang Goethe University Frankfurt am Main. The hospital was founded in 1914 and today it is a famous German medical institution with rich traditions. The hospital treats about 49,000 inpatients and 220,000 outpatients every year.

Acute Lymphoblastic Leukemia (ALL) Diagnosis
15829
Allogeneic bone marrow transplantation (stem cell transplant) in acute lymphoblastic leukemia (ALL)
259791
Consolidation treatment for acute lymphoblastic leukemia (ALL)
76148
location_onCountry: Germany
location_searchingCity: Frankfurt am Main
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University Hospital Muenster

9.8/10 from78 Votes

The University Hospital Muenster is one of the most respected multi-field medical centers in Germany. It consists of more than 30 departments and numerous research institutes and centers. Every year over 58,000 inpatients are treated here and nearly 475,000 patients receive medical care on the outpatient basis.

Acute Lymphoblastic Leukemia (ALL) Diagnosis
14105
Allogeneic bone marrow transplantation (stem cell transplant) in acute lymphoblastic leukemia (ALL)
240189
Consolidation treatment for acute lymphoblastic leukemia (ALL)
66644
location_onCountry: Germany
location_searchingCity: Muenster
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HELIOS Clinic Krefeld

9.7/10 from38 Votes

Founded in 2014, the HELIOS Clinic Krefeld is one of the most modern medical facilities in Germany today. A team of highly qualified specialists, innovative medical equipment and comfortable accommodation conditions – the clinic has everything to make the treatment run smoothly and efficiently.

Acute Lymphoblastic Leukemia (ALL) Diagnosis
13994
Consolidation treatment for acute lymphoblastic leukemia (ALL)
66635
High-intensity induction chemotherapy 1 block) of acute lymphoblastic leukemia (ALL)
39825
location_onCountry: Germany
location_searchingCity: Krefeld

Academic Hospital Harlaching Munich

9.2/10 from32 Votes

The Academic Hospital Harlaching is an emergency medical care facility offering top-class service. With about 700 beds, the hospital treats about 32,000 patients every year.

Acute Lymphoblastic Leukemia (ALL) Diagnosis
14215
Consolidation treatment for acute lymphoblastic leukemia (ALL)
66684
High-intensity induction chemotherapy 1 block) of acute lymphoblastic leukemia (ALL)
39533
location_onCountry: Germany
location_searchingCity: Munich
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Academic Hospital Asklepios Barmbek Hamburg

9.5/10 from23 Votes

As an Academic Hospital of the University of Hamburg, the Asklepios Barmbek Hospital offers a wide range of medical services in the field of conservative and surgical treatment. The hospital was opened in 2005 and today it is one of the best and modern medical centers in Europe.

Acute Lymphoblastic Leukemia (ALL) Diagnosis
14003
Consolidation treatment for acute lymphoblastic leukemia (ALL)
66836
High-intensity induction chemotherapy 1 block) of acute lymphoblastic leukemia (ALL)
39819
location_onCountry: Germany
location_searchingCity: Hamburg

Vivantes Humboldt Hospital Berlin

9.7/10 from23 Votes

An academic clinic of the university medical complex Charité, the Vivantes Humboldt Hospital is one of the largest specialized medical institutions in Berlin.

Acute Lymphoblastic Leukemia (ALL) Diagnosis
17858
Consolidation treatment for acute lymphoblastic leukemia (ALL)
86150
High-intensity induction chemotherapy 1 block) of acute lymphoblastic leukemia (ALL)
51340
location_onCountry: Germany
location_searchingCity: Berlin

Academic Hospital Schwabing Munich

8.5/10 from7 Votes

The Schwabing Clinic is a modern medical facility with a high level of service. The clinic has high-tech modern equipment, making it one of the best hospitals not only in Germany but also in Europe. There are comfortable single and double rooms with shower and toilet, TV, telephone and radio.

Acute Lymphoblastic Leukemia (ALL) Diagnosis
14178
Consolidation treatment for acute lymphoblastic leukemia (ALL)
66458
High-intensity induction chemotherapy 1 block) of acute lymphoblastic leukemia (ALL)
39394
location_onCountry: Germany
location_searchingCity: Munich
certificatecertificate

University Hospital Duesseldorf

9.9/10 from71 Votes

The University Hospital Dusseldorf  is a maximum-care hospital, and as such, we at Dusseldorf University, or UKD, are a byword for international top-quality service in all areas of medical care.

Acute Lymphoblastic Leukemia (ALL) Diagnosis
14067
Allogeneic bone marrow transplantation (stem cell transplant) in acute lymphoblastic leukemia (ALL)
240308
Consolidation treatment for acute lymphoblastic leukemia (ALL)
66569
location_onCountry: Germany
location_searchingCity: Duesseldorf
certificatecertificatecertificatecertificate

Tel Aviv Sourasky Medical Center

9.9/10 from23 Votes

The Tel Aviv Sourasky Medical Center (Ichilov) is the second largest and one of the most advanced healthcare and research institutions in Israel. Founded in 1961, it still enjoys popularity among the local population and draws thousands of international patients.

Acute Lymphoblastic Leukemia (ALL) Diagnosis
0.00
Consolidation treatment for acute lymphoblastic leukemia (ALL)
0.00
High-intensity induction chemotherapy 1 block) of acute lymphoblastic leukemia (ALL)
0.00
location_onCountry: Israel
location_searchingCity: Tel Aviv

University Hospital Cologne

9.8/10 from82 Votes

The University Hospital Cologne is included in the Focus magazine rating of top German hospitals 2017 and offers patients first-class medical care meeting the latest medical advancements.

Acute Lymphoblastic Leukemia (ALL) Diagnosis
14161
Allogeneic bone marrow transplantation (stem cell transplant) in acute lymphoblastic leukemia (ALL)
240245
Consolidation treatment for acute lymphoblastic leukemia (ALL)
66625
location_onCountry: Germany
location_searchingCity: Cologne
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Hannover Medical School

9.8/10 from43 Votes

The Hannover Medical School (MHH) is one of the most efficient medical universities in Germany, treating more than 63,000 inpatients and 460,000 outpatients annually.

Acute Lymphoblastic Leukemia (ALL) Diagnosis
16329
Allogeneic bone marrow transplantation (stem cell transplant) in acute lymphoblastic leukemia (ALL)
259493
Consolidation treatment for acute lymphoblastic leukemia (ALL)
75768
location_onCountry: Germany
location_searchingCity: Hannover
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About the disease

Acute lymphoblastic leukemia affects the blood and bone marrow. This type of cancer creates abnormal blood cells, also known as immature blood cells. ALL mostly damages bone marrow, because this is where white blood cells are produced. ALL tends to develop very rapidly. It mostly affects children, although it can also develop among adults.

ALL mostly develops when abnormalities in DNA coding appear. As a result, healthy cells start to proliferate, becoming eventually malignant instead of dying off and being replaced by new cells. When there are too many white blood cells circulating, they begin to produce lymphoblasts, which is a term for leukemic white blood cells. The reason why DNA coding becomes abnormal remains unknown. Certain genetic disorders are believed to contribute to the development of ALL, but this theory has not been proved yet.

Children who have previously undergone cancer treatments, such as chemotherapy or radiotherapy, have therefore been exposed to harmful radicals, making them an at-risk group.

According to Cancer Stat Facts, there were approximately 60,000 new cases of ALL in 2016. The 5-year survival rate for this type of cancer is 59.7%.

Symptoms

  • Bone pain
  • Paleness
  • Excessive bleeding from the gums
  • Headaches
  • Fever
  • Weight loss
  • Weakness
  • Nose bleeding

Diagnosis

  • A blood test is essential for diagnosing ALL. It can determine whether a person has too many white blood cells or if there are any immature cells that continue to proliferate and cause malignancy.
  • Bone marrow aspiration is used for a closer examination of the patient’s bone marrow. Usually, a sample of bone marrow is taken from the patient’s hip.
  • A CT and MRI scan of the patient’s brain is performed if there is reason to believe that ALL may have metastasized to the brain.

Treatment

  • High-intensity induction chemotherapy is used to kill as many malignant white blood cells and immature cells as possible. This aims to stop them from proliferating and to restore normal production of cells in the bone marrow. Depending on the stage the cancer has progressed to, doctors may prescribe 1 or 2 blocks of high agent drugs.
  • Consolidation treatment is most commonly used after induction chemotherapy. Any remaining leukemic cells in the brain or brainstem are killed. It is mostly used in stages 2 and 3 of ALL.
  • Radiation therapy of the brain is performed if ALL has metastasized to the brain. In this case, doctors use high-intensity radiation to destroy malignant cells in the affected parts of the brain. 
  • A stem cell transplant is performed if there is a high risk that cells will continue to proliferate and cause malignancy once the main treatment is finished. During this procedure, the affected bone marrow is replaced by healthy bone marrow from a donor. 



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