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Treatment of Clear Cell Renal Carcinoma in Germany | Best Hospitals, Doctors, Prices | Booking Health™

Clear Cell Renal Carcinoma. Treatment in Germany

Best Hospitals of Germany for Treatment of Clear Cell Renal Carcinoma | Booking Health helps you choose the right clinic and save money | ️Highly qualified specialists | ️Professional support on all stages of treatment | Send request 24/7!

Best hospitals and doctors for clear cell renal carcinoma treatment in Germany

Leading hospitals

Cost for treatment

Diagnostic tests for clear cell renal carcinoma
3.371,00 
Chemotherapy of clear cell renal carcinoma 1 course
11.023,06 
Radiotherapy of clear cell renal carcinoma
15.630,00 
Resection of clear cell renal carcinoma
17.927,10 
Cancer rehabilitation
On request
Hospital Harlaching Munich
Germany, Munich
Hospital Harlaching Munich
Overall rating9.2 / 10
According to the prestigious Focus magazine, the Hospital Harlaching Munich ranks among the top 20 medical centers in Bavaria, and is also one of the 100 best hospitals in Germany! The medical complex provides top-class medical care, which meets modern European standards. The medical facility is an Academic Hospital of the Ludwi
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Hannover Medical School (MHH)
Germany, Hannover
Hannover Medical School (MHH)
Overall rating9.8 / 10
The Hannover Medical School has the status of a leading German medical facility. The advanced medical technologies, highly qualified specialists, as well as productive research activities form a solid basis for top-class medical service of the world standard. The hospital is proud of its outstanding achievements in the treatment
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Hospital Cologne-Holweide
Germany, Cologne
Hospital Cologne-Holweide
Overall rating8.9 / 10
According to the reputable Focus magazine, the Hospital Cologne-Holweide ranks among the top medical centers in North Rhine-Westphalia! The medical complex is an academic hospital of the University of Cologne, providing patients with high-quality healthcare based on the latest achievements in university medicine. The hospital ad
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Hospital Kassel
Germany, Kassel
Hospital Kassel
Overall rating9.9 / 10
The Hospital Kassel is a progressive medical facility with a huge medical team, which provides high-quality medical services in all branches of modern medicine. The hospital is part of the regional medical Gesundheit Nordhessen Holding, which unites 5 top-class medical centers, including specialized rehabilitation clinics. With
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Meoclinic Hospital Berlin
Germany, Berlin
Meoclinic Hospital Berlin
Overall rating9.4 / 10
The Meoclinic Hospital Berlin is one of Germany's most renowned multidisciplinary private hospitals offering top-class and patient-centered medical care. The hospital opened its doors to patients back in 2000 and today is deservedly proud of its vast experience. It has 28 specialized departments, each of which is responsible
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Albertinen Hospital Hamburg
Germany, Hamburg
Albertinen Hospital Hamburg
Overall rating9.2 / 10
The Albertinen Hospital Hamburgwas founded in 1907 and nowadays it is one of the largest and the most advanced medical centers in Germany. The medical facility has the status of the Academic Hospital of the University of Hamburg, thanks to which it offers the most advanced diagnostic and treatment methods, which allow the doctor
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Nuremberg Hospital
Germany, Nuremberg
Nuremberg Hospital
Overall rating9 / 10
According to the reputable Focus magazine, the Nuremberg Hospital ranks among the top German medical facilities! The hospital is one of the largest, highly specialized medical centers in Europe and positions itself as the maximum care hospital. The healthcare facility is an academic hospital of the Paracelsus Medical University
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Marienhaus Hospital St. Elisabeth Neuwied
Germany, Neuwied
Marienhaus Hospital St. Elisabeth Neuwied
Overall rating9.8 / 10
The Marienhaus Hospital St. Elisabeth Neuwied is an advanced health facility with an excellent reputation in the national medical arena. It is the largest medical complex in the state of Rhineland-Palatinate. The Marienhaus Hospital St. Elisabeth Neuwied is an academic hospital of Johannes Gutenberg University Mainz and an acade
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Knappschaft Hospital Dortmund
Germany, Dortmund
Knappschaft Hospital Dortmund
Overall rating9.8 / 10
The Knappschaft Hospital Dortmund is a progressive multidisciplinary medical complex providing high quality medical care according to international standards. The hospital was founded in 1958, therefore it has a long history and rich clinical experience. After the overhaul and extensive works on the expansion and modernization o
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Asklepios Municipal Hospital Bad Wildungen
Germany, Bad Wildungen
Asklepios Municipal Hospital Bad Wildungen
Overall rating7.3 / 10
The Asklepios Municipal Hospital Bad Wildungen positions itself as a modern medical facility, which is focused on the provision of high-quality medical services using state-of-the-art medical technologies and advanced treatment methods. The hospital pays great attention to an individual approach to each patient, which is the bas
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Eichsfeld Hospital Heilbad Heiligenstadt
Germany, Heilbad Heiligenstadt
Eichsfeld Hospital Heilbad Heiligenstadt
Overall rating7.7 / 10
The Eichsfeld Hospital Heilbad Heiligenstadt is a reputable medical facility, whose patients can undergo high-quality diagnostics and treatment in accordance with European standards. The medical facility is an Academic Hospital of the University of Goettingen, so many local doctors are actively engaged in research activities and
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Urology Clinic Dortmund
Germany, Dortmund
Urology Clinic Dortmund
Overall rating9.8 / 10
The Urology Clinic Dortmund is a modern medical complex where patients can receive high-quality, personalized care. It is an academic clinic of Witten/Herdecke University that enables the active introduction of innovative diagnostic and treatment methods developed by leading professors from Germany and other countries into clini
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DKD HELIOS Clinic Wiesbaden
Germany, Wiesbaden
DKD HELIOS Clinic Wiesbaden
Overall rating9.2 / 10
The DKD HELIOS Clinic Wiesbaden has long made a name for itself in the international medical arena by introducing an optimal model of medical care, combining the use of the most advanced medical technologies, the experience of highly qualified doctors and impeccable quality of patient care. The medical facility first opened its
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Helios Hospital Berlin-Buch
Germany, Berlin
Helios Hospital Berlin-Buch
Overall rating9.7 / 10
According to the reputable Focus magazine, the Helios Hospital Berlin-Buch ranks among the top medical facilities in Germany! The clinic is proud of its rich history, which dates back over 100 years, as well as the status of a maximum care medical center with exceptionally high success treatment rates. The medical institution is
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Alfried Krupp Hospital in Essen-Steele
Germany, Essen
Alfried Krupp Hospital in Essen-Steele
Overall rating7.3 / 10
The Alfried Krupp Hospital in Essen-Steele is one of the best and most advanced medical facilities in the Ruhr area. The medical complex is an academic hospital of the University of Duisburg-Essen, thanks to which it extremely quickly implements innovative diagnostic and therapeutic methods into clinical practice. The hospital i
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Hospital Nordwest Frankfurt am Main
Germany, Frankfurt am Main
Hospital Nordwest Frankfurt am Main
Overall rating8.8 / 10
According to the reputable Focus magazine, the Hospital Nordwest Frankfurt am Main ranks among the top German medical facilities! The hospital has a reputation of a modern multidisciplinary medical center with excellent quality of services. The medical complex is an academic hospital of the Goethe University Frankfurt, thanks t
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| from Booking Health GmbH

Clear cell renal cancer is a pathological condition in which normal kidney cells are transformed into malignant (cancer) cells. Affected cells grow excessively, and malignant formations appear. In the course of their development, the pathological tissue may interfere with the functioning of the neighboring organs.

Content

  1. About kidney cancer
  2. Symptoms of clear cell renal carcinoma
  3. Treatment tactics
  4. Surgery for clear cell carcinoma
  5. How’s advanced cancer treated in Germany?
  6. Rehabilitation period
  7. The cost of treatment in the German hospitals
  8. Renal cancer treatment in Germany with Booking Health

About kidney cancer

 

Renal cell carcinoma belongs to the aggressive and unpredictable malignancies. In 25-30% of patients with renal cell carcinoma, there are distant metastases at time of diagnosis confirmation. After surgical treatment of patients with localized and locally advanced stages of the disease, the probability of recurrence and occurrence of metastases reaches 30%. The overall survival of patients with advanced clear cell carcinoma is not more than 5.5%, and that's why the problem of treatment of this group of patients is still urgent.

Malignant tumors of this type are characterized by invasive growth with destruction of surrounding tissues. In the case of kidneys, neoplasm development causes not only dysfunction, but also vascular damage and, consequently, chronic blood loss. This is fraught with anemia, blood clots stuck in the ureter and bladder, and acute urinary retention. The spread of atypical cells through the body leads to the formation of metastases. Secondary tumors may, in turn, localize in the respiratory organs, bones, and lungs.

Increased risk of disease is noted in patients with Hippel-Lindau disease, horseshoe kidneys, and acquired cysts that are accompanied by elevated levels of nitrogenous substances in the blood (uremia). The latter condition is the result of the impaired renal function.

Symptoms of clear cell renal carcinoma

 

Often clear cell renal carcinoma is detected by ultrasound or X-ray examination that is conducted for other pathologies. At its initial stages, renal cell cancer causes no pain or other symptoms. Therefore, the first signs of renal cell cancer often arise after the involvement of adjacent tissues or organs. The most typical manifestations are:

  • The appearance of blood in urine (visible or determined by the laboratory tests)
  • Pain in the lumbar region on the side or back
  • Presence of a palpable round or irregular mass at the waist, under the ribs
  • Swelling in the foot area, which may rise to the ankles and shins
  • Elevated blood pressure that does not respond well to hypotensive medications
  • Decreased red blood cell count, a drop in hemoglobin levels (persistent anemia)
  • Severe weakness, constant fatigue
  • A sharp decrease in appetite and, as a result, weight loss
  • Fever without signs of a cold or other infection

If it is a man, there may be dilated veins in the scrotal area (so-called varicocele). If the right testicle is particularly affected, there is a high risk of a large tumor in the kidney area. Some people have almost no symptoms until the advanced stages of clear cell renal carcinoma.

Treatment tactics

 

Renal cell carcinoma is in many ways a "unique" malignancy. Renal cell cancer can appear at a fairly young age and grow very slowly up to a certain point, without manifesting itself. At a certain stage, patients with clear cell renal carcinoma go through a transitional stage of a sudden change in the "behavior" of the neoplasm that rapidly progresses and gives metastases.

Unlike the vast majority of malignant tumors, renal cell cancer is virtually insensitive to radiation, hormonal or cytostatic therapy. This often deprives physicians of a chance to treat patients with advanced forms of renal cell carcinoma more effectively. Perhaps the situation will change with the implementation of a new therapeutic approach, that mainly focuses on targeted therapy (drugs that specifically block tumor proliferation factors). However, this treatment of kidney cancer is rather expensive and not available to all people.

The only method that can cure patients with renal cell carcinoma today is radical surgery, which completely removes or destroys the malignant tumor. Depending on the size of the carcinoma and its location, surgery can be radical (kidney removal – radical nephrectomy) or organ-preserving (kidney resection). The surgeon decides which tactics (resection or removal of the kidney) will be the most suitable in each case based on objective factors (characteristics of renal cell carcinoma, the patient's health status, etc.).

Surgery for clear cell carcinoma

 

Treatment of most neoplasms of the kidney begins with the excision of the primary tumor along with the tissues it has affected. The goal of the surgery is to get rid of the maximal volume of tissues affected by the tumor, given the fact that they are located in close proximity. Even for patients with metastatic renal cell carcinoma, surgery improves the effectiveness of further drug treatment and can be performed at the onset of pathology along with general systemic treatment. For example, various trials have demonstrated that the life expectancy of patients with metastases is significantly longer if surgery is performed before conservative treatment.

Nephrectomy is a well-known and common operation. Hundreds of interventions of this type are conducted each year for both renal cell cancer and other pathologies. Even though it is a major intervention, the risks and possible health problems are defined as minor if the patients with renal cell carcinoma have no significant comorbidities, mainly heart disease and liver pathology. Fatal risks of surgery are about 1% for patients with advanced forms of pathology.

Complications can sometimes occur when a neoplasm invades the nearby vessels, or when the tumor spreads to the adjacent organs. Vascular surgeries with tumor thrombus extension take longer.

There are 2 main types of interventions for kidney cancer. In the case of radical nephrectomy, the entire kidney with surrounding fatty tissue, lymph nodes, and, in some cases, the adherent adrenal gland is excised.

Radical surgery is often performed because the majority of cancer cells are more likely to be removed this way. However, partial nephrectomy is a suitable alternative for patients with small tumors. Therefore, the size and localization of the tumor determine the choice of surgery. In addition, partial nephrectomy is chosen in patients with renal insufficiency or second kidney affection.

How’s advanced cancer treated in Germany?

 

Treatment tactics for patients with clear cell carcinoma at an advanced stage is determined by the characteristics of the primary tumor, the number, size, and localization of distant metastases. The patient's general condition and the presence of concomitant diseases must be taken into account as well.

Surgery is performed rarely but still is conducted when the primary tumor and metastases (if they are found in only one organ) are resectable. In such a situation, they can be removed. Formally, this leads to a cure, as all tumor cells are eliminated. But often after, some patients with metastatic renal cell carcinoma may experience a relapse, since the patients’ body may contain undetected microscopic atypical cells.

For advanced renal cell cancer, surgery may be performed if there are unresectable metastases, but the primary tumor in the kidney is still resectable. In this case, the surgeon will remove the main tumor, this will help improve the condition of patients. After such surgery, adjuvant targeted therapy or immunotherapy is prescribed.

Small cells in the brain may be removed using stereotactic radiosurgery. Some patients with liver metastases may be treated with intraarterial chemotherapy, radiofrequency ablation, and chemoembolization. Specific treatment is required for ascites.

If surgical treatment is impossible, immunotherapy is prescribed. Targeted drugs might help as well, taking into account the fact that renal cell carcinoma responds poorly to chemotherapy. Pain management is also prescribed with drugs from the NSAID group (e.g. ibuprofen, naproxen) and/or with opioid analgesics.

Some patients have the opportunity to participate in clinical trials. On the specialized websites, patients can find out what trials are ongoing and who can become a candidate.

Rehabilitation period

 

During the period of rehabilitation, patients undergo follow-up examinations in order to exclude cell carcinoma recurrence. Physicians will give specific recommendations about the tests required and explain how often they need to be done. Patients with certain hereditary syndromes or genetic diseases are at risk of developing cancer in the future and need additional screenings.

Patients with a kidney removed can lead normal, active lives. However, families must discuss the need for medical care and lifestyle modifications with the attending physician. Patients should have medical examinations at least once a year. Examinations should include blood pressure measurements, kidney function tests, and urine analysis. If deviations are found, patients should be referred to a nephrologist.

The cost of treatment in the German hospitals

 

Renal cancer treatment in Germany is rightly associated with high quality and reliability, and this explains the desire of foreign patients to undergo diagnostics and therapy for clear cell carcinoma in German hospitals, especially when it comes to the most complex diagnoses and receiving the most qualified assistance. And as a consequence, one of the most sought-after areas of medical tourism is cancer treatment in Germany.

As for the cost of treatment in German hospitals, the prices vary depending on the peculiarities of the diagnosis, the number of procedures required for treatment, the level of German hospitals, additional services the patient requires, etc.

The average prices for procedures are listed below:

  • The cost of treatment with resection in the German hospitals starts at 11,865 EUR
  • The cost of treatment with radiotherapy starts at 15,300 EUR
  • The cost of treatment with chemotherapy starts at 3,469 EUR
  • The prices for cancer rehabilitation start at 951 EUR

If you want to know what the price is going to be for your case, visit the Booking Health website and click the request button.

Renal cancer treatment in Germany with Booking Health

 

Booking Health assists in obtaining medical visas and selecting the best German hospitals for patients with oncology.

Booking Health supports patients in every aspect of cancer treatment in Germany. We book flight tickets, transfers from/to the airport, and accommodation for a patient and the accompanying person. Booking Health provides patients with qualified medical interpreters for consultations and communication with medical personnel. Booking Health also translates your medical reports. If your treatment takes too long, Booking Health will help you with the extension of visas. And of course, we are always in touch. We will always help, give advice, and support.

Fill in the request form on the Booking Health website to start your treatment.

 

Authors: 

The article was edited by medical experts, board certified doctors Dr. Nadezhda Ivanisova and Dr. Sergey Pashchenko. For the treatment of the conditions referred to in the article, you must consult a doctor; the information in the article is not intended for self-medication!

 

Sources:

National Cancer Institute

American Cancer Society

MedlinePlus