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Treatment of Giant Cell Fibroblastoma (gcf) in Germany

Due to the difficulties associated with the organization of treatment in Turkey, Switzerland, South Korea and India, we are not currently processing requests to these regions.

If you are interested in treatment in Germany, please leave a request and our specialists will contact you as soon as possible.

 

Cost for treatment

Diagnostics of giant cell fibroblastoma (GCF)
971
Surgery resection of giant cell fibroblastoma (GCF)
4180
General therapeutic rehabilitation
565.57

Vivantes Neukölln Hospital Berlin

10/10
location_onGermany, Berlin

Department of Hematology, Oncology and Palliative Medicine

The Vivantes Neukölln Hospital is the maximum care hospital and one of the largest healthcare facilities in Berlin.  There are more than 20 specialized departments and centers, including pediatric departments. In total, the hospital has 1,200 beds. The hospital uses innovative technologies and the latest treatments, as
Diagnostics of giant cell fibroblastoma (GCF)
3449
Surgery resection of giant cell fibroblastoma (GCF)
13046

MediClin Robert Janker Clinic

9.5/10
location_onGermany, Bonn

Department of Oncology and Palliative Care

The MediClin Robert Janker Clinic is a progressive medical facility, which has all the very latest diagnostic and treatment methods for the recovery of health of patients who suffer from cancers. The clinic was founded by renowned radiologist and surgeon Robert Janker. Today, its history has more than 80 years of successful clin
Diagnostics of giant cell fibroblastoma (GCF)
3533

University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of Hematology, Oncology, Palliative Care, Rheumatology and Infectology

The University Hospital Ulm started its activities 35 years ago and during this time it has become one of the most prestigious medical institutions in Europe. The hospital is famous for its numerous discoveries and the world-class achievements in medicine and pharmaceuticals. The medical facility has 29 specialized departments a
Diagnostics of giant cell fibroblastoma (GCF)
3508
Surgery resection of giant cell fibroblastoma (GCF)
13282

Medias Cancer Clinic Burghausen

10/10
location_onGermany, Burghausen

Department of Oncology and Surgical Oncology

The Medias Cancer Clinic Burghausen positions itself as a private highly specialised medical facility with international leadership in cancer treatment. The key areas of specialization of the clinic include regional chemotherapy, surgical oncology, hyperthermia, immunotherapy and pain therapy. The ultimate value of each emp
Diagnostics of giant cell fibroblastoma (GCF)
3731

St. Vincentius Hospital Karlsruhe-Academic Hospital of the University of Freiburg

9.8/10
location_onGermany, Karlsruhe

Department of Hematology, Oncology, Immunology and Palliative Care

The St. Vincentius Clinic is the largest multidisciplinary medical institution and academiс hospital of the Albert Ludwig University of Freiburg. Treatment and diagnosis of patients is conducted by doctors with a scientific degree. They are introducing the latest progressive techniques. The clinic has at its disposal the latest
Diagnostics of giant cell fibroblastoma (GCF)
3509 help3189
Surgery resection of giant cell fibroblastoma (GCF)
11795

University Hospital Freiburg

9.7/10
location_onGermany, Freibung

Department of Hematology and Oncology

The University Hospital Freiburg is famous for its rich history and is one of the oldest and most prestigious medical facilities in Germany (one of the three best medical institutions in the country). The hospital was based on the Faculty of Medicine of the Albert Ludwig University of Freiburg, which celebrated its 550th anniver
Diagnostics of giant cell fibroblastoma (GCF)
3571
Surgery resection of giant cell fibroblastoma (GCF)
13858

University Hospital Frankfurt am Main

10/10
location_onGermany, Frankfurt am Main

Cancer Center

According to the reputable Focus magazine, the University Hospital Frankfurt am Main ranks among the top German medical facilities! The hospital was founded in 1914 and today is a well-known German medical facility, which combines rich traditions and scientific innovations. A medical team of more than 6,500 employees cares about
Diagnostics of giant cell fibroblastoma (GCF)
3250
Surgery resection of giant cell fibroblastoma (GCF)
12517

University Hospital Heidelberg

9.8/10
location_onGermany, Heidelberg

Department of Hematology, Oncology, Adult and Pediatric Rheumatology

According to Focus magazine, the University Hospital Heidelberg ranks among the top five hospitals in Germany! The hospital is one of the most advanced and reputable medical institutions not only in Germany, but throughout Europe. There are more than 43 specialized departments and 13 medical institutes, which cover all fields of
Diagnostics of giant cell fibroblastoma (GCF)
0
Surgery resection of giant cell fibroblastoma (GCF)
0

University Hospital Würzburg

9.2/10
location_onGermany, Würzburg

Department of Gastroenterology, Hematology, Oncology, Hepatology, Infectology, Rheumatology and Clinical Immunology

According to the Focus magazine in 2019, the University Hospital Würzburg ranks among the top national German hospitals! The hospital is one of the oldest medical facilities in Germany. The centuries-old traditions of first-class treatment are combined with the very latest achievements of modern evidence-based medicine and
Diagnostics of giant cell fibroblastoma (GCF)
3063
Surgery resection of giant cell fibroblastoma (GCF)
12482

University Hospital RWTH Aachen

8.7/10
location_onGermany, Aachen

Department of Oncology and Hematology

According to the prestigious Focus magazine, the University Hospital RWTH Aachen ranks among the top German hospitals! As a maximum care university medical facility, the hospital guarantees patients first-class medical services combined with a respectful and human attitude. The hospital integrates all the modern options for the
Diagnostics of giant cell fibroblastoma (GCF)
3630
Surgery resection of giant cell fibroblastoma (GCF)
13979

University Hospital Carl Gustav Carus Dresden

9.1/10
location_onGermany, Dresden

Department of Oncology

According to the reputable Focus magazine, the University Hospital Carl Gustav Carus Dresden ranks among the top five German hospitals! The hospital is the benchmark for modern high-quality medicine. Positioning itself as a maximum care medical facility, the hospital represents all medical fields. There are 26 specialized depart
Diagnostics of giant cell fibroblastoma (GCF)
4203
Surgery resection of giant cell fibroblastoma (GCF)
16128

University Hospital Erlangen

9.1/10
location_onGermany, Erlangen

Department of Hematology and Oncology

According to the Focus magazine, University Hospital Erlangen ranks among the best medical facilities in Germany! The hospital is one of the leading healthcare facilities in Bavaria and offers top-class medical care distinguished by the close intertwining of clinical activities with research and training of medical students. The
Diagnostics of giant cell fibroblastoma (GCF)
3524
Surgery resection of giant cell fibroblastoma (GCF)
13028

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of Hematology and Oncology

According to the prestigious Focus magazine, the University Hospital Halle (Saale) ranks among the top German medical facilities! The history of the hospital has more than 300 years, and during this time it managed to earn an excellent reputation not only in Germany, but throughout the world. The hospital positions itself as a s
Diagnostics of giant cell fibroblastoma (GCF)
3061
Surgery resection of giant cell fibroblastoma (GCF)
12314

University Hospital Hamburg-Eppendorf

9.2/10
location_onGermany, Hamburg

Department of Hematology, Oncology and Pulmonology

According to the Focus magazine, the University Hospital Hamburg-Eppendorf ranks among the top ten hospitals in Germany! Since its foundation in 1889, the hospital has taken a leading position in the European medical arena and still occupies it until today. A highly competent medical team of more than 11,000 employees takes care
Diagnostics of giant cell fibroblastoma (GCF)
3091
Surgery resection of giant cell fibroblastoma (GCF)
16264

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Charité Comprehensive Cancer Center

According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! The hospital is one of the largest and leading university medical complexes in Europe. The hospital in Germany provides modern diagnostics and treatment of patients, a
Diagnostics of giant cell fibroblastoma (GCF)
3226
Surgery resection of giant cell fibroblastoma (GCF)
18353

University Hospital Bonn

9.2/10
location_onGermany, Bonn

Department of Oncology, Hematology, Rheumatology and Immunoncology

According to the authoritative Focus magazine, the University Hospital Bonn ranks among the top ten medical facilities in Germany! The hospital was opened on January 1, 2001, although in fact it inherits the medical facility, which operated at the Faculty of Medicine of the University of Bonn. The hospital in Germany combin
Diagnostics of giant cell fibroblastoma (GCF)
3597
Surgery resection of giant cell fibroblastoma (GCF)
13688
| from Booking Health GmbH

Content

  1. Overview
  2. The features of giant cell fibroblastoma (GCF)
  3. Symptoms of giant cell fibroblastoma (GCF)
  4. Diagnostics of the giant cell fibroblastoma in Germany
  5. Treatment options for giant cell fibroblastoma
  6. Surgery
  7. Prognosis
  8. Benefits of cancer treatment in Germany
  9. German hospitals to undergo treatment of giant cell fibroblastoma
  10. The cost of treatment in Germany
  11. How can I undergo cancer treatment in Germany?

 

Malignant soft tissue tumors are comparatively rare. They account for 0.7% of all malignant neoplasms in adults, but in childhood, their frequency reaches 6.5%, and they rank 5th among the most common malignant neoplasms of childhood.

Overview

 

Giant cell fibroblastoma (GCF) is considered a form of dermatofibrosarcoma protuberans. Like many other types of tumors, dermatofibrosarcoma protuberans occur because cells begin to divide rapidly, eventually transforming into abnormal ones.

Dermatofibrosarcoma protuberans is a type of tumor that consists of pathologically altered fibroblasts (cell of connective tissue). In most cases, this tumor develops in the skin and may eventually spread to the lungs, although this happens relatively rare. In most cases, treatment of dermatofibrosarcoma protuberans requires surgical removal, since other methods have a very low success rate.

Pathology develops due to the fusion of two specific genes. The resulting fusion gene (that appears to be common for dermatofibrosarcoma protuberans and giant cell fibroblastoma) does not function as it should function normally. Instead, it produces substances that stimulate tumor growth, although the gene itself perceives it as normal functioning.

At first, the whole process may manifest in the form of a small bump under the skin. Over time, dermatofibrosarcoma protuberans can invade muscles and spread to surrounding organs.

The causes and mechanisms of the development of both giant cell fibroblastoma (GCF) and dermatofibrosarcoma protuberans remain unclear. Some researchers point to a possible connection with injury, others – to the presence of genetic abnormalities.

The features of giant cell fibroblastoma (GCF)

 

The tumor can be located anywhere in the body, but more often it is localized in the area of the chest, spine, abdomen, or extremities.

If we’re talking about dermatofibrosarcoma protuberans, it sometimes appears on the neck or scalp. Unlike giant cell fibroblastoma, dermatofibrosarcoma protuberans is prone to metastasizing, but the lower limbs and distal upper limbs are rarely affected though.

At the initial stages, the surface of both giant cell fibroblastoma and dermatofibrosarcoma protuberans is smooth or slightly bumpy. The color is brownish, reddish, purple, or bluish. As a result of slow growth over several years, the primary focus turns into a tumor-like node protruding above the surface of the skin. The skin over the protruding dermatofibrosarcoma protuberans or giant cell fibroblastoma is usually atrophied. Initially, the node is freely movable. As the underlying tissues grow and adhesions arise, the mobility of both giant cell fibroblastoma and dermatofibrosarcoma protuberans decreases.

How big the tumor is depends on the course of the disease, but the size can range from a few millimeters to 10-15 centimeters. Usually, a giant cell fibroblastoma, like dermatofibrosarcoma protuberans, is diagnosed when its diameter reaches several centimeters.

The giant cell fibroblastoma is dense, fibrous, and consists of bundles of spindle-shaped cells. The molecular and cellular structure is somewhat elongated, with different levels of cell differentiation in each case.

The tumor forms many root-like small outgrowths that penetrate the underlying tissues. At the initial stages, it is a formation of nodules. Subsequently, the number and size of nodules in the formation increase. The skin over the giant cell fibroblastoma is usually thinned. With the disease being undetected for a long time, bleeding or erosion may appear in the place of the neoplasm location.

Symptoms of giant cell fibroblastoma (GCF)

 

Usually, both giant cell fibroblastoma and dermatofibrosarcoma protuberans are asymptomatic. Less often patients complain of minor or moderate pain in the area of the neoplasm. With a prolonged course of giant cell fibroblastoma or dermatofibrosarcoma protuberans, erosions can be found on the surface of the tumor.

Sometimes, usually after repeated relapses, dermatofibrosarcoma protuberans metastasizes to regional lymph nodes and distant organs. It should be noted that a giant cell fibroblastoma, which isn't usually characterized by metastasizing, can invade the underlying tissues, affecting the bones, muscles, and organs located nearby.

Diagnostics of the giant cell fibroblastoma in Germany

 

The diagnosis of giant cell fibroblastoma in German hospitals is established based on clinical manifestations and data from additional studies. As the disease is accompanied by nonspecific symptoms, the main diagnostic technique is the examination of a tissue sample taken during biopsy.

There are no specific immunochemical markers of the tumor. The final diagnosis of giant cell fibroblastoma is based on molecular and histological examination data. To detect distant cancer cells, ultrasound scan of internal organs, chest X-ray, and other imaging techniques are used.

Treatment options for giant cell fibroblastoma

 

Surgery is often the preferred treatment for giant cell fibroblastoma. Removing the tumor also allows the surrounding tissue to be examined for signs of invasion. Fortunately, this procedure is relatively straightforward and rarely leads to the development of complications. Even when surgery is performed, subsequent treatment with radiation or chemotherapy is often carried out as a preventive measure.

Chemotherapy is usually used to shrink the tumor. Mild chemotherapeutic drugs are often used for various types of chemotherapy for giant cell fibroblastoma, which in some cases give promising results. There is also a good chance that radiation therapy will be used in combination with chemotherapy.

Surgery

 

Surgical treatment is carried out on an outpatient basis or in a hospital setting.

The most effective is the Mohs operation, during which the dermato-oncologist excises the visible tumor and, if necessary, the surrounding tissue. After excision, the clinical laboratory assistant performs mapping – makes 1 mm thick slices of a protruding dermatofibrosarcoma, stains the samples with special dyes, and examines them under a microscope to determine the boundaries of the tumor.

Based on the data obtained during the microscopic examination, the doctor determines in the boundaries of giant cell fibroblastoma, and, if necessary, excises the tissues nearby. This technique allows doctors to accurately determine the true boundaries of the tumor and makes it possible to reduce the number of relapses.

Prognosis

 

The prognosis for giant cell fibroblastoma, especially in the case of early detection, is quite favourable.

However, the prognosis for giant cell fibroblastoma depends on the course of the disease and the number of relapses. According to various data, the risk of recurrence after radical surgery ranges from 10 to 60%, which may be due to both differences in the severity and spreading of the process or the chosen surgical technique.

While it is not considered to be the most dangerous of all tumor types, it is important to understand that giant cell fibroblastoma is a serious disease. Detection at the advanced stages of the disease has a significant impact on the treatment process, as well as on the duration of the recovery period. By following the doctor's recommendations, both during the treatment with radiation and chemotherapy and after surgery, you can minimize symptoms or discomfort that may be present.

Benefits of cancer treatment in Germany

 

Oncology treatment in Germany has long been a gold standard in medicine. German hospitals are showing amazing statistics. They have about 40% more treatment success than other countries in Europe and Asia – all due to the effectiveness of German medicine.

Cancer treatment in Germany has several advantages:

  • Impeccable diagnostic system
  • Transparent pricing system
  • Widespread use of advanced robotic technologies in medicine
  • Disciplined and professional staff

All modern instrumental and laboratory research methods are available for patients. At the same time, diagnostic buildings are located on the same territory as inpatient departments. This means that the time is used as efficiently as possible.

In cancer treatment in Germany robot surgeons and modern laparoscopic installations are not considered advanced technology. These are usual assistants of the oncologist surgeon.

Oncology is one of the most developed areas in German medicine. Local oncologists study at universities for a long time and must undergo practical training in the best clinics in the country and the world. The middle and junior medical staff do their job clearly, and they are always ready to come to the rescue.

German hospitals to undergo treatment of giant cell fibroblastoma in

 

German hospitals are known for their excellent service, advanced equipment, highly qualified specialists, and proved treatment efficiency.

Hospitals that specialize in the treatment of giant cell fibroblastoma are:

  1. Vivantes Neukolln Hospital Berlin
  2. MediClin Robert Janker Clinic
  3. University Hospital Ulm
  4. Medias Cancer Clinic Burghausen
  5. St. Vincentius Hospital Karlsruhe-Academic Hospital of University of Freiburg
  6. University Hospital Freiburg
  7. University Hospital Frankfurt am Main

The cost of treatment in Germany

 

Since 2003, the diagnosis-related pricing system has been used in Germany. This is a standard system for determining the price of treatment, depending on the diagnosis of the patient and the method of treatment of the disease chosen by the German doctors. Thus, the cost of medical services is approximately the same in different hospitals in Germany. However, the price can fluctuate depending on the medical procedures involved in the treatment plan.

The cost of treatment with tumor resection is 10,825-18,353 EUR. The cost of treatment with additional diagnostics of giant cell fibroblastoma is 14,000-21,500 EUR.

Of course, the cost of treatment in Germany cannot be called cheap, but the results achieved by German specialists are truly priceless.

How can I undergo cancer treatment in Germany?

 

If you are dissatisfied with the level of medicine in your native country, you can come to Germany for treatment.

In German clinics, you will undergo precise diagnostics and treatment of high quality that will be minimally invasive, safe, and effective. Prices here are not the lowest, but quite affordable.

To organize a trip to Germany, contact the medical tourism company Booking Health. Booking Health will help you find a good clinic and the best specialist, and will provide language support throughout your stay in Germany.

All you need to do is leave a request on the Booking Health website. You will be contacted and provided with all the information about cancer treatment in Germany.

Authors: Dr. Nadezhda IvanisovaDr. Sergey Pashchenko




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