Treatment of Henoch-Schonlein Purpura
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University Hospital Ulm
Department of Hematology, Oncology, Palliative Care, Rheumatology and Infectology
Medicana International Ankara Hospital
Department of Hematology and Bone Marrow Transplantation
Samsung Medical Center Seoul
Department of Oncology and Hematology
Tel Aviv Sourasky Medical Center
Department of Hematology
University Hospital Freiburg
Department of Hematology and Oncology
University Hospital Heidelberg
Department of Hematology, Oncology, Adult and Pediatric Rheumatology
University Hospital Frankfurt am Main
Department of Hematology, Oncology, Hemostaseology, Rheumatology and Infectology
University Hospital Würzburg
Department of Gastroenterology, Hematology, Oncology, Hepatology, Infectology, Rheumatology and Clinical Immunology
University Hospital RWTH Aachen
Department of Oncology and Hematology
University Hospital Erlangen
Department of Hematology and Oncology
University Hospital Halle (Saale)
Department of Hematology and Oncology
University Hospital Hamburg-Eppendorf
Department of Hematology, Oncology and Pulmonology
Charite University Hospital Berlin
Charité Comprehensive Cancer Center
University Hospital Bonn
Department of Oncology, Hematology, Rheumatology and Immunoncology
University Hospital of Ludwig Maximilian University of Munich
Department of Oncology and Hematology
Henoch-Schonlein purpura is an inflammation of small blood vessels. This disease is mostly pediatric. As a result of inflammation in small blood vessels, blood vessels can start to leak. Mostly, blood vessels of the skin, kidneys and intestines are affected. Henoch-schonlein purpura manifests itself as a rash, which is followed by little bruises. Bruises, in this case, are mostly numerous. Rash and bruising can develop on the legs and buttocks. Henoch-Schonlein purpura is mostly common among children aged 2 to 11, but in rare cases it can affect people of other age groups as well. It has been noted that Henoch-schonlein purpura is more prevalent among boys. If an adult has Henoch-schonlein purpura, he/she is more likely to have more severe symptoms than children.
Most commonly, Henoch-schonlein purpura lasts about 4 weeks, in some cases 6 weeks, and after that the condition resolves. In most cases, Henoch-schonlein purpura does not have any serious complication, but nonetheless a child needs to be checked after recovery to see if there had been any damage to the kidneys and intestines. After Henoch-schonlein purpura has passed, a child needs to be regularly checked by the doctor to assure that small blood vessels function normally. Although the exact cause of Henoch-schonlein purpura has not been identified, it is believed that abnormal immune system response to respiratory infections which a child can contract during winter or autumn plays a vital role in causing development of Henoch-schonlein purpura.
- Rash
- Bruising
- Joint pain
- Swelling
- Abdominal pain
- In some cases blood in the urine if kidneys have been damaged
- Fever
- Headaches
- During a general examination, a doctor will examine the rash to determine its nature. He will also look if there is bruising.
- A urinalysis is used to check the function of kidneys.
- A blood test is used to determine if there is an infection.
- A biopsy of the skin is sometimes used if the only manifestation of Henoch-schonlein purpura is rash and a doctor needs to confirm the diagnosis.
- Conservative treatment is used to alleviate the symptoms and also reduce joint pain. It is also used to precipitate the recovery and ensure its safe outcome. A doctor may prescribe anti-inflammatory drugs. Corticosteroids can be prescribed in severe cases, but they are rarely used.
- Extracorporeal blood correction is used if Henoch-schonlein purpura has caused sepsis. Then small blood vessels need to be purified in order to reduce inflammation.