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Treatment of Liver Fibrosis in Germany

Due to the difficulties associated with the organization of treatment in Turkey, Switzerland, South Korea and India, we are not currently processing requests to these regions.

If you are interested in treatment in Germany, please leave a request and our specialists will contact you as soon as possible.

 

Cost for treatment

Liver Fibrosis Diagnostics
715
Diagnosis and conservative treatment of liver fibrosis
1935
General therapeutic rehabilitation
565.57

University Hospital Duesseldorf

8.5/10
location_onGermany, Duesseldorf

Department of Gastroenterology, Hepatology and Infectology

According to the authoritative Focus magazine, the University Hospital Duesseldorf ranks among the top Germany hospitals! The hospital is an excellent example of a combination of high-quality health care, research and teaching activities. With more than 50,000 inpatients and about 300,000 outpatients every year, the hospital is
Liver Fibrosis Diagnostics
3063
Diagnosis and conservative treatment of liver fibrosis
7665

University Hospital of Ludwig Maximilian University of Munich

10/10
location_onGermany, Munich

Department of Gastroenterology and Hepatology

According to the Focus magazine, the University Hospital of Ludwig Maximilian University of Munich is regularly ranked among the best medical institutions in Germany! The hospital is the largest multidisciplinary medical facility, as well as a leading research and training center in Germany and Europe. The hospital is proud of i
Liver Fibrosis Diagnostics
3119
Diagnosis and conservative treatment of liver fibrosis
7629

University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of Gastroenterology and Hepatology

The University Hospital Ulm started its activities 35 years ago and during this time it has become one of the most prestigious medical institutions in Europe. The hospital is famous for its numerous discoveries and the world-class achievements in medicine and pharmaceuticals. The medical facility has 29 specialized departments a
Liver Fibrosis Diagnostics
2907
Diagnosis and conservative treatment of liver fibrosis
7234

University Hospital Heidelberg

9.8/10
location_onGermany, Heidelberg

Department of Gastroenterology, Hepatology and Infectology

According to Focus magazine, the University Hospital Heidelberg ranks among the top five hospitals in Germany! The hospital is one of the most advanced and reputable medical institutions not only in Germany, but throughout Europe. There are more than 43 specialized departments and 13 medical institutes, which cover all fields of
Liver Fibrosis Diagnostics
0
Diagnosis and conservative treatment of liver fibrosis
0

University Hospital Bonn

9.2/10
location_onGermany, Bonn

Department of Gastroenterology, Hepatology, Nephrology, Infectology, Endocrinology and Diabetology

According to the authoritative Focus magazine, the University Hospital Bonn ranks among the top ten medical facilities in Germany! The hospital was opened on January 1, 2001, although in fact it inherits the medical facility, which operated at the Faculty of Medicine of the University of Bonn. The hospital in Germany combin
Liver Fibrosis Diagnostics
2987
Diagnosis and conservative treatment of liver fibrosis
7587

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Department of Hepatology and Gastroenterology

According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! The hospital is one of the largest and leading university medical complexes in Europe. The hospital in Germany provides modern diagnostics and treatment of patients, a
Liver Fibrosis Diagnostics
3755
Diagnosis and conservative treatment of liver fibrosis
9384

University Hospital Carl Gustav Carus Dresden

9.1/10
location_onGermany, Dresden

Department of Gastroenterology and Hepatology

According to the reputable Focus magazine, the University Hospital Carl Gustav Carus Dresden ranks among the top five German hospitals! The hospital is the benchmark for modern high-quality medicine. Positioning itself as a maximum care medical facility, the hospital represents all medical fields. There are 26 specialized depart
Liver Fibrosis Diagnostics
3533
Diagnosis and conservative treatment of liver fibrosis
8616

University Hospital Rechts der Isar Munich

9.8/10
location_onGermany, Munich

Department of Gastroenterology, Hepatology, Endocrinology and Infectology

The University Hospital Rechts der Isar Munich was founded in 1834. It combines long traditions with the very latest advances in modern medicine. The medical facility includes 33 specialized departments and 20 interdisciplinary centers, where patients can receive top-class medical care in all medical fields. The hospital annuall
Liver Fibrosis Diagnostics
3035
Diagnosis and conservative treatment of liver fibrosis
7690

University Hospital Jena

8.9/10
location_onGermany, Jena

Department of Gastroenterology, Hepatology and Infectology

According to the prestigious Focus magazine, the University Hospital Jena regularly ranks among the top German medical facilities! The hospital has positioned itself as a multidisciplinary medical facility with a long history of more than 200 years. Since its foundation, the hospital has been constantly developing and modernizin
Liver Fibrosis Diagnostics
3164
Diagnosis and conservative treatment of liver fibrosis
7573

University Hospital Tuebingen

9.2/10
location_onGermany, Tuebingen

Department of Gastroenterology, Hepatology and Infectology

According to the prestigious medical publication Focus, the University Hospital Tuebingen ranks among the top five German hospitals! The hospital was founded in 1805, therefore it is proud of its long history, unique experience, and outstanding achievements in the field of medical care, as well as research and teaching activitie
Liver Fibrosis Diagnostics
2924
Diagnosis and conservative treatment of liver fibrosis
7301

University Hospital Essen

9.6/10
location_onGermany, Essen

Department of Gastroenterology and Hepatology

According to the authoritative Focus magazine the University Hospital Essen ranks among the top German hospitals! With 27 specialized departments and 24 institutes, the hospital in Germany is a maximum care medical facility. The hospital has 1,300 beds for inpatient treatment. A highly qualified medical team of more than 6,000 e
Liver Fibrosis Diagnostics
2744
Diagnosis and conservative treatment of liver fibrosis
7055

HELIOS University Hospital Wuppertal

9.8/10
location_onGermany, Wuppertal

Department of Gastroenterology, Hepatology and Endocrinology

According to the prestigious Focus magazine, the HELIOS University Hospital Wuppertal ranks among the top medical facilities in Germany! The hospital rightfully enjoys the status of the maximum care medical facility and provides its high-quality services in all modern fields of medicine. The hospital operates on the basis of the
Liver Fibrosis Diagnostics
2826
Diagnosis and conservative treatment of liver fibrosis
6996

University Hospital Saarland Homburg

9.8/10
location_onGermany, Homburg

Department of Gastroenterology, Hepatology, Endocrinology, Diabetology and Nutritional Medicine

The University Hospital Saarland is the largest hospital in the city of Homburg and the most important medical facility in the region. The hospital, which currently has 30 specialized departments and 20 institutes, was founded in 1947 and operates on the basis of the Saarland University. The hospital plays a leading role in medi
Liver Fibrosis Diagnostics
2730
Diagnosis and conservative treatment of liver fibrosis
6605

Academic Municipal Hospital Karlsruhe

9.8/10
location_onGermany, Karlsruhe

Department of Gastroenterology, Hepatology and Diabetology

According to the prestigious Focus magazine, the Academic Municipal Hospital Karlsruhe ranks among the top German hospitals! The hospital positions itself as a modern maximum care medical facility, which combines long traditions and progressive achievements of modern medicine. The hospital operates on the basis of the University
Liver Fibrosis Diagnostics
2726
Diagnosis and conservative treatment of liver fibrosis
6607

Hannover Medical School (MHH)

9.8/10
location_onGermany, Hannover

Department of Gastroenterology, Hepatology and Endocrinology

The Hannover Medical School has the status of a leading German medical facility. The advanced medical technologies, highly qualified specialists, as well as productive research activities form a solid basis for top-class medical service of the world standard. The hospital is proud of its outstanding achievements in the treatment
Liver Fibrosis Diagnostics
3052
Diagnosis and conservative treatment of liver fibrosis
7626

Hospital Nordwest Frankfurt am Main

8.8/10
location_onGermany, Frankfurt am Main

Department of Gastroenterology, Hepatology, Cardiology and Pulmonology

According to the reputable Focus magazine, the Hospital Nordwest Frankfurt am Main ranks among the top German medical facilities! The hospital has a reputation of a modern multidisciplinary medical center with excellent quality of services. The medical complex is an academic hospital of the Goethe University Frankfurt, thanks t
Liver Fibrosis Diagnostics
3017
Diagnosis and conservative treatment of liver fibrosis
7590
| from Booking Health GmbH

Content

  1. How common is liver fibrosis?
  2. The process of fibrosis formation
  3. What causes liver fibrosis?
  4. Symptoms
  5. Complications
  6. Diagnostics of liver fibrosis in Germany
  7. The importance of liver fibrosis treatment
  8. Principles of liver fibrosis treatment in Germany
  9. Methods for liver fibrosis treatment in Germany
  10. The cost of treatment in Germany
  11. How to undergo liver fibrosis treatment in Germany?

 

Liver fibrosis is a liver disease characterized by an excessive development of fibrous connective tissue under the influence of prolonged inflammation.

How common is liver fibrosis?

 

Liver fibrosis affects millions of people, most of whom have a history of chronic hepatitis or alcoholic liver disease. In the US, the liver fibrosis is observed in about 360 cases per 100 thousand people, and it is the leading cause of death among diseases of the digestive system (about 30 thousand deaths per year). Besides, about 10,000 deaths are due to liver cancer, which often occurs at the advanced stage of liver fibrosis.

Clinical manifestations of liver fibrosis vary from mild to the pronounced medical signs. About 40% of patients with this liver disease are asymptomatic for many years, but the liver disease inevitably progresses and ends with the development of complications.

The process of fibrosis formation

 

Liver fibrosis develops as a result of the response of liver cells to damage resulting from the inflammatory process caused by exposure to various damaging agents. This process is accompanied by the activation of inflammatory cells, which produce active substances. Among other things, these substances stimulate synthesis of collagen – a special protein that forms the basis of the body's connective tissue and fills the spaces between cells.

Initially, fibrous tissue, composed of collagen and its derivatives, plays a protective role. It stops the spread of infectious processes to neighboring areas, isolates areas with pathological changes from the systemic blood flow, etc. Over time, the amount of fibrous tissue increases and it replaces healthy liver tissue, which eventually disrupts liver function and hampers blood circulation in it.

What causes liver fibrosis?

 

Liver fibrosis arises when the liver is severely affected by inflammation. In such condition an attempt to repair itself ultimately fails, because liver cells are being replaced by fibrous tissue. And this tissue eventually intermits the normal functioning of the liver.

Liver fibrosis is a consequence of certain major medical conditions, including:

  • Alcoholism
  • Chronic hepatitis
  • Fatty liver disease

Other possible causes of liver fibrosis include biliary duct inflammation, autoimmune diseases, hereditary metabolic disorders, and intake of certain therapeutic medicines.

Symptoms

 

The first medical sign in patients with liver fibrosis is constant fatigue for no apparent reason. Patients feel weak, become irritable, and high-reactive. Also, patients often experience headaches.

Then specific medical signs appear that include:

  • Nausea that sometimes leads to vomiting
  • Alternating diarrhea and constipation
  • Pain in the abdomen, aggravated by eating fried or fatty foods, as well as by drinking alcohol
  • Reluctant eating, up to a complete lack of appetite for a long time
  • Heaviness in the stomach
  • Bloating

All of the above may indicate other diseases. Therefore, at this stage, there are not enough indicating factors to diagnose liver disease. Moreover, in about 20% of people who suffered from liver fibrosis, it is possible to determine the true cause of the symptoms only after death.

The initial stage of liver damage with fibrosis is characterized by an increase in the size of the organ. In addition, there may be a decrease in the level of leukocytes, platelets, and erythrocytes. As a result, patients have anemia and thrombocytopenia. An enlargement of the spleen, varicose veins in the esophagus, and hemorrhages indicate that the disease is progressing to the stage of cirrhosis.

Complications

 

Lack of timely liver fibrosis treatment can lead to the development of severe complications that can be fatal. These include hepatocellular insufficiency (liver cells practically do not perform their functions), gastrointestinal bleeding, increased pressure in the portal vein, and hepatic coma.

The main danger of liver fibrosis is its transition to cirrhosis. Unfortunately, this is a very common situation, since fibrosis is practically asymptomatic and many people "feel" it already at the stage of cirrhosis, when symptoms characteristic of liver failure appear.

Diagnostics of liver fibrosis in Germany

 

The main methods for diagnosing liver fibrosis are:

  • Ultrasound scan of the liver
  • CT, MRI scan of the liver
  • Ultrasound elastography
  • Magnetic resonance elastography
  • Blood tests for markers of liver function, such as bilirubin levels
  • Liver biopsy

As a rule, not all of the above diagnostic tests are involved in making an accurate diagnosis. The choice of methods for diagnosing liver fibrosis in Germany is carried out by the doctor based on medical information about the liver disease obtained earlier, and the medical information further needed.

The importance of liver fibrosis treatment

 

Liver fibrosis is a chronic liver disease in which connective tissue grows in the liver, replacing functional cells. As a rule, this occurs against the background of inflammatory processes of different etiology.

With progression, changes in the structure of the liver lead to liver failure and cirrhosis. These are very dangerous conditions that can be fatal. Therefore, the absence of liver fibrosis treatment is unacceptable. And the sooner an accurate diagnosis of the medical condition is carried out and an adequate liver fibrosis treatment is selected, the more successful the fight against the liver disease will be.

Liver fibrosis treatment in Germany includes the use of the most effective methods of treatment aimed at maintaining the functionality of the organ and preventing the development of complications, primarily cirrhosis.

Principles of liver fibrosis treatment in Germany

 

Liver fibrosis can be mild, moderate, or severe. Each of the stages has its own characteristics of the clinical course. Liver fibrosis treatment in Germany is carried out taking into account the stage of the liver disease.

In German hepatology centers, an integrated approach is used, which includes pathogenetic and symptomatic therapy. Thus, it is possible to stop or slow down the process of replacing the liver parenchyma with connective tissue as much as possible, and avoid the development of complications.

The most important thing in treatment is to determine the causes of liver fibrosis. If it is possible to accurately determine the causative agent and eliminate it, this will stop the degradation processes in the tissues. And over time, under favorable conditions, the liver will be able to regenerate and restore functionality of the affected areas.

Therefore, liver fibrosis treatment in Germany is primarily aimed at fighting the liver diseases that provoke its onset. For each liver disease, there are specially developed treatment tactics. So, when viral hepatitis is detected, the main task is to destroy the virus in the body; with hemochromatosis – to remove excess iron from the body; with alcohol abuse – to exclude alcohol and get rid of the consequences of its toxic effects. The liver fibrosis treatment also includes treatment with therapeutic medicines and nutrition correction.

Correctly selected liver fibrosis treatment allows effective coping with the liver disease and stops destructive processes in the liver. The choice of tactics for the liver fibrosis treatment depends on the stage of liver disease. The earlier the liver disease is detected and measures are taken, the better the treatment prognosis is.

Methods for liver fibrosis treatment in Germany

 

Therapy for liver fibrosis includes mainly conservative methods and detoxification therapy.

Drug therapy includes eliminating the cause of liver disease and minimizing the intensity of pathological processes. As a rule, hepatoprotectors, immunomodulators, and immunosuppressants are used. If necessary, liver fibrosis treatment with antibiotic therapy (to exclude the primary infection), treatment of alcohol dependence, obesity, normalization of blood glucose levels, stabilization of the cardiological system are possible.

In patients with liver fibrosis, diet is one of the primary prescriptions. It is necessary to draw up a balanced dietary plan, excluding all foods that complicate the work of the liver. Withdrawal of alcohol is mandatory. It may be necessary to exclude therapeutic medicines that were previously used by patients.

Another method of moderate liver fibrosis treatment is stem cell treatment. The patient's own stem cells are harvested. Their purifying and cultivation are carried out. After these, they are transplanted into the liver, where they activate restoration of liver structures.

If the liver is affected seriously, a liver transplant is performed. Such a medical intervention requires special equipment and the highest level of skill of the surgeon, therefore in many countries, it is practiced rarely. However, in German hepatology centers, such medical procedures are performed regularly, and have already become commonplace with very high efficiency though.

In some cases, surgical intervention is possible. However, the choice of the method for liver fibrosis treatment in hepatology centers is made by the doctors. Attending physicians always inform patients about the possible complications of each treatment option. Each case is considered individually and a medical tactics is developed that will allow patients to get the best result.

The cost of treatment in Germany

 

The cost of treatment of liver fibrosis depends on the stage of the liver disease and the treatment plan that is prescribed by the doctor according to the patient’s medical indications.

The cost of treatment with conservative therapy and diagnosis making in Germany ranges from 6,600 EUR to 9,384 EUR, where the price for diagnostics alone is about 3000 EUR.

It is possible to determine the approximate cost of treatment in Germany for each specific case. Specialists of Booking Health are able to draw up a preliminary price for medical procedures and the overall cost of treatment based on your medical information.

How to undergo liver fibrosis treatment in Germany?

 

If you are a patient with liver fibrosis and want to have the best doctors by your side, the right decision is to choose a liver fibrosis treatment in Germany. The best clinics in Germany successfully treat the most complex liver diseases and demonstrate excellent treatment results. Besides, in Germany, you will have an opportunity to participate in experimental liver fibrosis treatment.

Booking Health will help you find a clinic that specializes in fibrosis and relevant liver diseases. Booking Health will also take care of all organizational issues so that you can fully focus on restoring your health.

If you need any additional information about the treatment of liver fibrosis, send a request on the Booking Health website, and a medical advisor will contact you.

Authors: Dr. Nadezhda IvanisovaDr. Farrukh Ahmed




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