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Diagnostic and treatment of Moyamoya disease

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Cost for treatment

Moyamoya disease diagnostics
 from  535
Treatment of moyamoya disease with a shunt overlay with interponate
 from  7215
Neurological rehabilitation Phase C
 from  540

University Hospital of Ludwig Maximilian University of Munich

10/10
location_onGermany, Munich

Department of Adult and Pediatric Neurosurgery

According to the Focus magazine, the University Hospital of Ludwig Maximilian University of Munich is regularly ranked among the best medical institutions in Germany! The hospital is the largest multidisciplinary medical facility, as well as a leading research and training center in Germany and Europe. The hospital is proud of i
Moyamoya disease diagnostics
2074
Treatment of moyamoya disease with a shunt overlay with interponate
22041

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Department of Adult and Pediatric Neurosurgery

According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! The hospital is one of the largest and leading university medical complexes in Europe. The hospital in Germany provides modern diagnostics and treatment of patients, a
Moyamoya disease diagnostics
2604
Treatment of moyamoya disease with a shunt overlay with interponate
28820

University Hospital Freiburg

9.7/10
location_onGermany, Freibung

Department of Adult and Pediatric Neurosurgery

The University Hospital Freiburg is famous for its rich history and is one of the oldest and most prestigious medical facilities in Germany (one of the three best medical institutions in the country). The hospital was based on the Faculty of Medicine of the Albert Ludwig University of Freiburg, which celebrated its 550th anniver
Moyamoya disease diagnostics
2012
Treatment of moyamoya disease with a shunt overlay with interponate
21739

University Hospital Frankfurt am Main

10/10
location_onGermany, Frankfurt am Main

Department of Adult and Pediatric Neurosurgery

According to the reputable Focus magazine, the University Hospital Frankfurt am Main ranks among the top German medical facilities! The hospital was founded in 1914 and today is a well-known German medical facility, which combines rich traditions and scientific innovations. A medical team of more than 6,500 employees cares about
Moyamoya disease diagnostics
1998
Treatment of moyamoya disease with a shunt overlay with interponate
19333

University Hospital Würzburg

9.2/10
location_onGermany, Würzburg

Department of Adult and Pediatric Neurosurgery

According to the Focus magazine in 2019, the University Hospital Würzburg ranks among the top national German hospitals! The hospital is one of the oldest medical facilities in Germany. The centuries-old traditions of first-class treatment are combined with the very latest achievements of modern evidence-based medicine and
Moyamoya disease diagnostics
1911
Treatment of moyamoya disease with a shunt overlay with interponate
19218

University Hospital Bonn

9.2/10
location_onGermany, Bonn

Department of Neurosurgery

According to the authoritative Focus magazine, the University Hospital Bonn ranks among the top ten medical facilities in Germany! The hospital was opened on January 1, 2001, although in fact it inherits the medical facility, which operated at the Faculty of Medicine of the University of Bonn. The hospital in Germany combin
Moyamoya disease diagnostics
2029
Treatment of moyamoya disease with a shunt overlay with interponate
21547

University Hospital Carl Gustav Carus Dresden

9.1/10
location_onGermany, Dresden

Department of Adult and Pediatric Neurosurgery

According to the prestigious Focus magazine, the University Hospital Carl Gustav Carus Dresden is among the top three hospitals in Germany! The hospital is the embodiment of the standards of modern high-quality medicine. Since the hospital positions itself as a maximum care medical facility, it represents all medical fields. The
Moyamoya disease diagnostics
2358
Treatment of moyamoya disease with a shunt overlay with interponate
25699

University Hospital Erlangen

9.1/10
location_onGermany, Erlangen

Department of Adult and Pediatric Neurosurgery, Spinal Surgery

According to the Focus magazine, University Hospital Erlangen ranks among the best medical facilities in Germany! The hospital is one of the leading healthcare facilities in Bavaria and offers top-class medical care distinguished by the close intertwining of clinical activities with research and training of medical students. The
Moyamoya disease diagnostics
1948
Treatment of moyamoya disease with a shunt overlay with interponate
20442

University Hospital Hamburg-Eppendorf

9.2/10
location_onGermany, Hamburg

Department of Adult and Pediatric Neurosurgery

According to the Focus magazine, the University Hospital Hamburg-Eppendorf ranks among the top ten hospitals in Germany! Since its foundation in 1889, the hospital has taken a leading position in the European medical arena and still occupies it until today. A highly competent medical team of more than 11,000 employees takes care
Moyamoya disease diagnostics
2287
Treatment of moyamoya disease with a shunt overlay with interponate
25633

University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of Neurosurgery

The University Hospital Ulm started its activities 35 years ago and during this time it has become one of the most prestigious medical institutions in Europe. The hospital is famous for its numerous discoveries and the world-class achievements in medicine and pharmaceuticals. The medical facility has 29 specialized departments a
Moyamoya disease diagnostics
2055
Treatment of moyamoya disease with a shunt overlay with interponate
20621

University Hospital Heidelberg

9.8/10
location_onGermany, Heidelberg

Department of Adult and Pediatric Neurosurgery

According to the Focus magazine, the University Hospital Heidelberg ranks among the top five hospitals in Germany! The hospital is one of the most advanced and reputable medical institutions not only in Germany, but throughout Europe. There are more than 43 specialized departments and 13 medical institutes, which cover all field
Moyamoya disease diagnostics
0
Treatment of moyamoya disease with a shunt overlay with interponate
0

University Hospital Essen

9.6/10
location_onGermany, Essen

Department of Adult and Pediatric Neurosurgery

According to the authoritative Focus magazine the University Hospital Essen ranks among the top German hospitals! With 27 specialized departments and 24 institutes, the hospital in Germany is a maximum care medical facility. The hospital has 1,300 beds for inpatient treatment. A highly qualified medical team of more than 6,000 e
Moyamoya disease diagnostics
1892
Treatment of moyamoya disease with a shunt overlay with interponate
19473

University Hospital Jena

8.9/10
location_onGermany, Jena

Department of Adult and Pediatric Neurosurgery

According to the prestigious Focus magazine, the University Hospital Jena regularly ranks among the top German medical facilities! The hospital has positioned itself as a multidisciplinary medical facility with a long history of more than 200 years. Since its foundation, the hospital has been constantly developing and modernizin
Moyamoya disease diagnostics
2044
Treatment of moyamoya disease with a shunt overlay with interponate
22096

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of Neurosurgery

According to the prestigious Focus magazine, the University Hospital Halle (Saale) ranks among the top German medical facilities! The history of the hospital has more than 300 years, and during this time it managed to earn an excellent reputation not only in Germany, but throughout the world. The hospital positions itself as a s
Moyamoya disease diagnostics
1938
Treatment of moyamoya disease with a shunt overlay with interponate
19374

University Hospital Marburg UKGM

8.6/10
location_onGermany, Marburg

Department of Adult and Pediatric Neurosurgery

The University Hospital Marburg UKGM offers patients modern diagnostics and comprehensive therapy at the international level. As a maximum care hospital, the medical facility specializes in all fields of modern medicine ranging from ophthalmology to traumatology and dentistry. The main areas of specialization of the hospital are
Moyamoya disease diagnostics
1825
Treatment of moyamoya disease with a shunt overlay with interponate
17941

University Hospital Rechts der Isar Munich

9.8/10
location_onGermany, Munich

Department of Adult and Pediatric Neurosurgery

According to the prestigious FOCUS magazine, the University Hospital Rechts der Isar Munich ranks among the Germany's top medical institutions! Founded in 1834, the hospital combines long traditions and the very latest achievements of modern medicine. The medical facility includes 33 specialized departments, 20 interdiscipli
Moyamoya disease diagnostics
2061
Treatment of moyamoya disease with a shunt overlay with interponate
21639
| from Booking Health GmbH

About the disease

Moyamoya disease, also known as Moyamoya syndrome, is a pediatric condition, when carotid arteries become thickened and are not able to supply sufficient amount of blood to the brain vessels. As a result, child does not receive enough oxygen-rich blood and there is increased risk of clot formation in the brain. Such risk exists because the brain, trying to compensate for the lack of blood supply, creates new blood vessels, which start to clot together. The most dangerous complication of Moyamoya disease is a stroke, which can be caused by such cerebrovascular disorder, as this syndrome.

According to Boston Children's Hospital,  Moyamoya disease is a rare condition, affecting only several hundred children worldwide annually. Most commonly this disease is diagnosed at the age of 7, although in rare cases it can first manifest itself in adulthood after many years of unnoticed progression.

Moyamoya disease is believed to be caused by genetic defects. Some of the children with this condition also have Down syndrome and other congenital conditions. It is more common in girls. In some children the first indicator of Moyamoya disease is a brain hemorrhage, while in others - mini stroke. Nonetheless, this syndrome develops very slowly and before there is a real danger of stroke, child has pronounced symptoms of this disease, which usually allows the doctor to carry out diagnosis on time.   

Symptoms

  • Recurrent headaches
  • Slurred speech
  • Fatigue
  • Weakness on right/left side of the body
  • Seizures
  • Nausea
  • Blurred vision
  • Irritability
  • Changes in behaviour

Diagnosis

  • MRI is the most commonly used diagnostic measure for this type of disease. it creates the image of the brain, which allows the doctor to see if there is an excessive number of blood vessels.
  • CT scan is a more precise imaging test, which creates the three-dimensional image of the brain and determines if there is insufficient supply of oxygen-rich blood through carotid arteries.
  • Angiogram is also an imaging test, which shows the carotid artery and helps doctor determine the extent of its narrowing and thickness.

Treatment

Surgery is the only possible treatment for this disease, as it is impossible to fully stop the process of artery narrowing by anti-clotting drugs or any other blockers. Most often, medications in this case are used only to prepare the child for surgery, which aims to restore normal blood flow to the brain.

  • Arterial bypass surgery restores the blood flow by joining blood vessel from the scalp directly to the brain.
  • Shunt overlay with interpolation is a surgery, during which hollow tube is placed in the brain to redirect the blood flow and normalize the supply of oxygen-rich blood to the brain. 

Authors: Dr. Nadezhda Ivanisova, Dr. Sergey Pashchenko




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