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Ovarian Polyembryoma - Best Hospitals, Doctors, Prices - Booking Health

Treatment of Ovarian Polyembryoma

Ovarian polyembryoma | Information about hospitals and doctors | Rankings | Clinics | Prices | Send request to the hospital

Best hospitals and doctors for ovarian polyembryoma treatment abroad

Leading hospitals

Cost for treatment

Diagnostics of polyembryoma ovarian
3.385,00 
Chemotherapy of polyembryoma ovarian (1 course)
5.593,75 
Surgery treatment of polyembryoma ovarian
4.101,88 
Cancer rehabilitation
On request
The Hannover Medical School has the status of a leading German medical facility. The advanced medical technologies, highly qualified specialists, as well as productive research activities form a solid basis for top-class medical service of the world standard. The hospital is proud of its outstanding achievements in the treatment
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Luisenhospital Aachen
Luisenhospital Aachen
Overall rating9.8 / 10
The Luisenhospital Aachen is a modern health facility that offers top-class European-standard service. The medical complex is an academic hospital of RWTH Aachen University, which provides patients with access to innovations in diagnosis and treatment. The hospital first opened its doors to patients in 1967 and has been carrying
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According to the reputable Focus magazine, the Hospital Cologne-Holweide ranks among the top medical centers in North Rhine-Westphalia! The medical complex is an academic hospital of the University of Cologne, providing patients with high-quality healthcare based on the latest achievements in university medicine. The hospital ad
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According to the prestigious Focus magazine, the Hospital Harlaching Munich ranks among the top 20 medical centers in Bavaria, and is also one of the 100 best hospitals in Germany! The medical complex provides top-class medical care, which meets modern European standards. The medical facility is an Academic Hospital of the Ludwi
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The Park-Clinic Weissensee Berlin is a progressive medical facility with the highest standards of medical care. The medical facility is an academic hospital of the Charite University Hospital Berlin, thanks to which the specialists have access to all medical innovations. The clinic was opened on April 1, 1997, on the former Weis
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The Marienhaus Hospital St. Elisabeth Neuwied is an advanced health facility with an excellent reputation in the national medical arena. It is the largest medical complex in the state of Rhineland-Palatinate. The Marienhaus Hospital St. Elisabeth Neuwied is an academic hospital of Johannes Gutenberg University Mainz and an acade
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The MEDIAN Rehabilitation Clinic Schlangenbad positions itself as a modern clinic providing high-quality rehabilitation services to patients with rheumatic, gynecological and psychosomatic disorders of any complexity. The clinic was founded in the 1970s, and therefore it has a rich tradition and successful experience in patient
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The Hirslanden Clinic La Colline Geneva is a multidisciplinary medical facility, where the patient will benefit from an impeccable quality of medical service, responsive care and a humane attitude. The clinic provides both inpatient treatment and outpatient care. There are 67 beds available for hospitalization. The basis of succ
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Every year, Zurich attracts thousands of foreigners with its best Swiss clinics. One of them is Klinik Im Park that has been providing a constantly high level of medical services, professional care and friendly atmosphere for 25 years. Why exactly do patients choose Swiss clinics? The reason is that our specialists will do their
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The Meoclinic Hospital Berlin is one of Germany's most renowned multidisciplinary private hospitals offering top-class and patient-centered medical care. The hospital opened its doors to patients back in 2000 and today is deservedly proud of its vast experience. It has 28 specialized departments, each of which is responsible
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The Albertinen Hospital Hamburgwas founded in 1907 and nowadays it is one of the largest and the most advanced medical centers in Germany. The medical facility has the status of the Academic Hospital of the University of Hamburg, thanks to which it offers the most advanced diagnostic and treatment methods, which allow the doctor
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The Memorial Sisli Hospital Istanbul is the largest and leading medical complex in Turkey, which meets the highest standards of medical care when providing the advanced diagnostics and treatment using the very latest methods. The hospital is part of the Memorial Health Group – it was the first project of this provider of m
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The Memorial Bahçelievler Hospital Istanbul is an advanced multidisciplinary medical center that began its clinical practice in 2018. It is part of the world famous Memorial Healthcare Group. The hospital was designed in accordance with the very latest standards of modern architecture with the aim of providing top-class m
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Nuremberg Hospital
Nuremberg Hospital
Overall rating9 / 10
According to the reputable Focus magazine, the Nuremberg Hospital ranks among the top German medical facilities! The hospital is one of the largest, highly specialized medical centers in Europe and positions itself as the maximum care hospital. The healthcare facility is an academic hospital of the Paracelsus Medical University
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The Hirslanden Clinic Aarau enjoys the status of one of the largest and most successful private medical facilities in Bern and Zurich. The clinic is part of the Hirslanden Network known in Europe, which is a provider of first-class medical services in Switzerland. The main areas of specialization of the clinic in Aarau include c
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The Eichsfeld Hospital Heilbad Heiligenstadt is a reputable medical facility, whose patients can undergo high-quality diagnostics and treatment in accordance with European standards. The medical facility is an Academic Hospital of the University of Goettingen, so many local doctors are actively engaged in research activities and
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An ovarian polyembryoma is a rare germ cell tumor. The neoplasm is diagnosed predominantly in young women. Ovarian polyembryomas practically do not occur in their pure form. The elements of a polyembryoma are usually part of mixed tumors. The larger its proportion, the worse the prognosis, since this type of tumor is more aggressive than most types of cancer. It is a complex task to treat this cancer, and it also recurs more often. This cancer is resistant to irradiation and to many chemotherapy agents. Despite all the difficulties, doctors in German Oncology Centers successfully cope with ovarian polyembryomas.

Content

  1. Treatment principles
  2. Surgical treatment
  3. Chemotherapy
  4. Other treatment methods
  5. Why is it worth undergoing polyembryoma treatment in Germany?

Treatment principles

 

The main treatment options for patients with a newly diagnosed ovarian polyembryoma are:

  • surgery and follow-up monitoring (early stage only);
  • surgery followed by chemotherapy (the most common treatment option);
  • chemotherapy followed by surgery (if a tumor has reached a large size at the time of its detection and this needs to be reduced in order to try to remove it completely);
  • only chemotherapy (if a surgical intervention is contraindicated or the patient refuses it).

Radiation therapy is usually not used. A polyembryoma is highly resistant to radiation. Radiation therapy can sometimes be carried out in the advanced stages of the disease to relieve symptoms and reduce the risk of complications.

Surgical treatment

 

Treatment usually begins with tumor removal. Operations can be performed at any stage of an oncological disease, from the early stages to the advanced ones. However, the extent of surgical interventions and the goals of treatment differ significantly. The disease can be cured completely in the early stages, but as the tumor process progresses, the cure becomes less and less likely, since cancer spreads through the abdominal cavity. It is almost impossible to destroy all cancer cells. Nonetheless, even in such a case, good results can be obtained: the disease can be controlled for many years by reducing the tumor mass with cytoreductive surgery and destroying the remaining cancer cells with chemotherapy agents.

There are several types of surgical interventions for patients with an ovarian polyembryoma:

Bilateral adnexectomy is the removal of the ovaries with fallopian tubes. This is the main operation at the initial stage. It is performed on all women who do not plan to conceive a baby. As a rule, surgical interventions are performed via an open rather than a laparoscopic approach. This is necessary for performing surgical staging procedures. When both ovaries are removed, a woman cannot become pregnant unless she has frozen her eggs beforehand. However, the uterus is preserved, so pregnancy is possible with the help of IVF. Embryos are transferred into the uterus from a woman's own frozen or donated oocytes.

Unilateral adnexectomy is another surgical opinion. The removal of two ovaries is more effective, since in this case the risk that the tumor recurs is reduced. However, such an operation entails two problems: infertility and premature menopause. Since the majority of patients are children and young women, the removal of both ovaries should be avoided whenever possible. Doctors can only remove the uterine appendages on one side. As the risk of oncology recurrence increases in this case, women need more accurate monitoring: regular tumor marker blood tests, gynecological examinations, and instrumental tests of the pelvic organs. Should any signs of recurrence be detected, a second operation can be performed to cure the cancer.

Surgical staging is a number of procedures that are performed during the operation. If surgical intervention is performed at an early stage, the goal of treatment is the complete elimination of the ovarian polyembryoma. Therefore, doctors have to make sure that they are really dealing with the early stage and that the tumor has not spread to other organs. As part of surgical staging, suspicious lymph nodes are also removed and examined. Doctors accurately examine the entire abdominal cavity, take a biopsy, smears and swabs from suspicious areas of the peritoneum.

Cytoreductive surgery is performed at an advanced stage of cancer. The aim of this intervention is to reduce the tumor mass as much as possible. Doctors remove the uterus, appendages, omentum, as well as all tumor foci detected in the abdominal cavity. Sometimes there are quite a few of them, so doctors have to partially remove the intestine, bladder, and sometimes other organs as well. After the removal of the tumors, a reconstructive stage of the operation is performed to restore the damaged organs.

Depending on the extent, cytoreduction can be:

  • complete cytoreduction that involves the removal of all visible tumors;
  • optimal cytoreduction that involves the removal of all tumors larger than 1 cm;
  • suboptimal cytoreduction, after which at least one tumor larger than 1 cm remains.

Suboptimal cytoreduction is actually an unsuccessful operation, since if tumor foci larger than 1 cm remain, the survival rates of patients are approximately the same as in the case of chemotherapy alone, without any surgical intervention. Optimal cytoreduction significantly increases life expectancy as it is more effective than drug therapy. The best results can be achieved with complete cytoreduction.

Chemotherapy

 

The second most important treatment method for an ovarian polyembryoma is chemotherapy. This is prescribed to most patients with a polyembryoma, except at a very early stage of the disease. Doctors use different chemotherapy regimens, such as PEP, PEI, TIP, and VeIP. The choice of the regimen is determined by the goal of therapy, the stage of the disease, the response to previous treatment, and the health status of a woman.

Chemotherapy can be used in the following cases:

  • chemotherapy after surgery is the most common option, as the use of drugs allows doctors to destroy the remaining cancer cells in the body and lower the likelihood of recurrence;
  • chemotherapy before surgery can be used for advanced polyembryomas, as doctors can shrink the tumors to improve the chances of achieving a complete cytoreduction with follow-up surgery;
  • chemotherapy can be used as the main treatment method for those for whom surgery is contraindicated (but if there are no medical contraindications, it is advisable to perform surgical treatment even at the advanced stage, since it increases the survival rate of patients);
  • chemotherapy can be used to treat recurrence if it is impossible to perform a second operation to remove the tumor.

Most women respond to initial treatment. However, in the future, the tumor may return, in which case the therapy must be repeated. The further treatment regimen depends on the timing of the onset of recurrence. If the tumor has recurred in a year or more, doctors may use the same chemotherapy regimen that has been successfully tried before. However, in the early recurrence that occurs less than 6 months later, the chances of success with the same drugs are low. Therefore, doctors use second-line therapy. They use drugs from other pharmacological groups. If there is no response to treatment, third-line therapy and so on may be used until the result is achieved.

Other treatment methods

 

If other treatment methods do not work, doctors may try non-standard methods to control oncological diseases:

High-dose chemotherapy with a stem cell transplant. This technique is currently being studied in clinical trials. Doctors use high doses of drugs to destroy all cancer cells in the body. This is followed by a donor stem cell transplant, which restores impaired hematopoiesis and activates a "graft-versus-tumor" effect.

Targeted therapy and immunotherapy. Drugs from different pharmacological groups are still being tested in clinical trials and are not part of a standard treatment. Patients who are not responding to conventional chemotherapy may be eligible to participate in these trials.

Radiation therapy. This treatment option has low efficiency for a polyembryoma, but doctors in developed countries use innovative options of radiation therapy, which are more accurate and sparing for surrounding tissues. They help to deliver more radiation to the tumor to overcome radioresistance. Doctors often use radiation therapy not to destroy the primary tumor, but to control metastases, for example, in the brain.

Chemoembolization. This therapeutic procedure can be used for metastatic liver lesions. This is a minimally invasive procedure that is performed from the inside of the blood vessels. Doctors use tiny microspheres containing chemotherapy agents to block the arteries that supply the tumor. As a result, the metastatic tumor dies due to the lack of blood supply, and the remaining cancer cells in the liver are destroyed by drugs that are released from the microspheres over several weeks.

Why is it worth undergoing polyembryoma treatment in Germany?

 

German hospitals offer modern equipment, innovative methods, and drugs. The high level of qualification of German doctors is beyond doubt. When you get medical services in this country, you can count on the best results with minimal health risks.

There are several reasons for you to undergo your ovarian polyembryoma treatment in a German hospital:

  • the possibility of a complete cure of cancer at an early stage;
  • preservation of the reproductive function for young women;
  • highly accurate intraoperative diagnostics to determine the exact stage of an ovarian polyembryoma and choose the best treatment tactics;
  • successful cytoreductive operations even at the advanced stages of the ovarian polyembryoma;
  • when performing cytoreductive operations, doctors mostly manage to achieve a complete cytoreduction, which significantly improves the prognosis for patients;
  • cancer can be cured or controlled with drugs for many years if the tumor is detected at the advanced stage;
  • doctors use the most effective combinations of chemotherapy drugs that have proven themselves in clinical trials.

You are welcome to use the Booking Health service to go to Germany to undergo your ovarian polyembryoma treatment in one of the best clinics in the world. On our website, you can find the cost of treatment in Germany, compare prices in different hospitals, and book your treatment at the best price. The Booking Health staff will help you to find the best German hospital and take care of all travel arrangements. The cost of treatment in Germany will be lower for you due to the lack of additional taxes for foreign patients. If you make your treatment appointment through our service, the initial price will be final: this will not increase even if additional medical procedures are required, as their cost will be covered by insurance.

 

Authors: 

The article was edited by medical experts, board-certified doctors Dr. Nadezhda Ivanisova and Dr. Sergey Pashchenko. For the treatment of the conditions referred to in the article, you must consult a doctor; the information in the article is not intended for self-medication!

 

Sources:

MedlinePlus

Verywell Health

Science Direct