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Treatment of Zollinger–Ellison Syndrome

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Cost for treatment

Diagnosis of Zollinger–Ellison syndrome
 from  8800
Diagnosis and conservative treatment of Zollinger–Ellison syndrome
 from  2673
Surgical treatment of Zollinger–Ellison syndrome
 from  8641

University Hospital Duesseldorf

8.5/10
location_onGermany, Duesseldorf

Department of Gastroenterology, Hepatology and Infectology

According to the authoritative Focus magazine, the University Hospital Duesseldorf ranks among the top Germany hospitals! The hospital is an excellent example of a combination of high-quality health care, research and teaching activities. With more than 50,000 inpatients and about 300,000 outpatients every year, the hospital is
Diagnosis of Zollinger–Ellison syndrome
26807
Diagnosis and conservative treatment of Zollinger–Ellison syndrome
9396
Surgical treatment of Zollinger–Ellison syndrome
25550

University Hospital of Ludwig Maximilian University of Munich

10/10
location_onGermany, Munich

Department of Gastroenterology and Hepatology

According to the Focus magazine, the University Hospital of Ludwig Maximilian University of Munich is regularly ranked among the best medical institutions in Germany! The hospital is the largest multidisciplinary medical facility, as well as a leading research and training center in Germany and Europe. The hospital is proud of i
Diagnosis of Zollinger–Ellison syndrome
27013
Diagnosis and conservative treatment of Zollinger–Ellison syndrome
9468
Surgical treatment of Zollinger–Ellison syndrome
25883

University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of Gastroenterology and Hepatology

The University Hospital Ulm started its activities 35 years ago and during this time it has become one of the most prestigious medical institutions in Europe. The hospital is famous for its numerous discoveries and the world-class achievements in medicine and pharmaceuticals. The medical facility has 29 specialized departments a
Diagnosis of Zollinger–Ellison syndrome
25151
Diagnosis and conservative treatment of Zollinger–Ellison syndrome
9066
Surgical treatment of Zollinger–Ellison syndrome
24394

University Hospital Frankfurt am Main

10/10
location_onGermany, Frankfurt am Main

Department of Gastroenterology, Hepatology, Pulmonology, Allergology, Endocrinology and Diabetology

According to the reputable Focus magazine, the University Hospital Frankfurt am Main ranks among the top German medical facilities! The hospital was founded in 1914 and today is a well-known German medical facility, which combines rich traditions and scientific innovations. A medical team of more than 6,500 employees cares about
Diagnosis of Zollinger–Ellison syndrome
8800
Diagnosis and conservative treatment of Zollinger–Ellison syndrome
8594
Surgical treatment of Zollinger–Ellison syndrome
23114

University Hospital Heidelberg

9.8/10
location_onGermany, Heidelberg

Department of Gastroenterology, Hepatology and Infectology

According to the Focus magazine, the University Hospital Heidelberg ranks among the top five hospitals in Germany! The hospital is one of the most advanced and reputable medical institutions not only in Germany, but throughout Europe. There are more than 43 specialized departments and 13 medical institutes, which cover all field
Diagnosis of Zollinger–Ellison syndrome
0
Diagnosis and conservative treatment of Zollinger–Ellison syndrome
0
Surgical treatment of Zollinger–Ellison syndrome
0

University Hospital Würzburg

9.2/10
location_onGermany, Würzburg

Department of Gastroenterology, Hematology, Oncology, Hepatology, Infectology, Rheumatology and Clinical Immunology

According to the Focus magazine in 2019, the University Hospital Würzburg ranks among the top national German hospitals! The hospital is one of the oldest medical facilities in Germany. The centuries-old traditions of first-class treatment are combined with the very latest achievements of modern evidence-based medicine and
Diagnosis of Zollinger–Ellison syndrome
22349
Diagnosis and conservative treatment of Zollinger–Ellison syndrome
8065
Surgical treatment of Zollinger–Ellison syndrome
22762

University Hospital Bonn

9.2/10
location_onGermany, Bonn

Department of Gastroenterology, Hepatology, Nephrology, Infectology, Endocrinology and Diabetology

According to the authoritative Focus magazine, the University Hospital Bonn ranks among the top ten medical facilities in Germany! The hospital was opened on January 1, 2001, although in fact it inherits the medical facility, which operated at the Faculty of Medicine of the University of Bonn. The hospital in Germany combin
Diagnosis of Zollinger–Ellison syndrome
26844
Diagnosis and conservative treatment of Zollinger–Ellison syndrome
9444
Surgical treatment of Zollinger–Ellison syndrome
25766

University Hospital Carl Gustav Carus Dresden

9.1/10
location_onGermany, Dresden

Department of Gastroenterology and Hepatology

According to the prestigious Focus magazine, the University Hospital Carl Gustav Carus Dresden is among the top three hospitals in Germany! The hospital is the embodiment of the standards of modern high-quality medicine. Since the hospital positions itself as a maximum care medical facility, it represents all medical fields. The
Diagnosis of Zollinger–Ellison syndrome
31508
Diagnosis and conservative treatment of Zollinger–Ellison syndrome
10608
Surgical treatment of Zollinger–Ellison syndrome
29858

University Hospital RWTH Aachen

8.7/10
location_onGermany, Aachen

Department of Gastroenterology, Metabolic Disorders and Internal Intensive Care

According to the prestigious Focus magazine, the University Hospital RWTH Aachen ranks among the top German hospitals! As a maximum care university medical facility, the hospital guarantees patients first-class medical services combined with a respectful and human attitude. The hospital integrates all the modern options for the
Diagnosis of Zollinger–Ellison syndrome
26545
Diagnosis and conservative treatment of Zollinger–Ellison syndrome
9244
Surgical treatment of Zollinger–Ellison syndrome
25597

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Department of Hepatology and Gastroenterology

According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! The hospital is one of the largest and leading university medical complexes in Europe. The hospital in Germany provides modern diagnostics and treatment of patients, a
Diagnosis of Zollinger–Ellison syndrome
35544
Diagnosis and conservative treatment of Zollinger–Ellison syndrome
12024
Surgical treatment of Zollinger–Ellison syndrome
34252

University Hospital Hamburg-Eppendorf

9.2/10
location_onGermany, Hamburg

Department of Gastroenterology, Hepatology and Infectology

According to the Focus magazine, the University Hospital Hamburg-Eppendorf ranks among the top ten hospitals in Germany! Since its foundation in 1889, the hospital has taken a leading position in the European medical arena and still occupies it until today. A highly competent medical team of more than 11,000 employees takes care
Diagnosis of Zollinger–Ellison syndrome
31165
Diagnosis and conservative treatment of Zollinger–Ellison syndrome
10716
Surgical treatment of Zollinger–Ellison syndrome
29771

University Hospital Marburg UKGM

8.6/10
location_onGermany, Marburg

Department of Gastroenterology, Endocrinology, Metabolism and Clinical Infectology

The University Hospital Marburg UKGM offers patients modern diagnostics and comprehensive therapy at the international level. As a maximum care hospital, the medical facility specializes in all fields of modern medicine ranging from ophthalmology to traumatology and dentistry. The main areas of specialization of the hospital are
Diagnosis of Zollinger–Ellison syndrome
22594
Diagnosis and conservative treatment of Zollinger–Ellison syndrome
7987
Surgical treatment of Zollinger–Ellison syndrome
21701

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of Gastroenterology, Hepatology and Pulmonology

According to the prestigious Focus magazine, the University Hospital Halle (Saale) ranks among the top German medical facilities! The history of the hospital has more than 300 years, and during this time it managed to earn an excellent reputation not only in Germany, but throughout the world. The hospital positions itself as a s
Diagnosis of Zollinger–Ellison syndrome
23793
Diagnosis and conservative treatment of Zollinger–Ellison syndrome
8378
Surgical treatment of Zollinger–Ellison syndrome
22865

University Hospital Rechts der Isar Munich

9.8/10
location_onGermany, Munich

Department of Gastroenterology, Hepatology, Endocrinology, Diabetology and Infectology

According to the prestigious FOCUS magazine, the University Hospital Rechts der Isar Munich ranks among the Germany's top medical institutions! Founded in 1834, the hospital combines long traditions and the very latest achievements of modern medicine. The medical facility includes 33 specialized departments, 20 interdiscipli
Diagnosis of Zollinger–Ellison syndrome
26960
Diagnosis and conservative treatment of Zollinger–Ellison syndrome
9515
Surgical treatment of Zollinger–Ellison syndrome
25361

University Hospital Jena

8.9/10
location_onGermany, Jena

Department of Gastroenterology, Hepatology and Infectology

According to the prestigious Focus magazine, the University Hospital Jena regularly ranks among the top German medical facilities! The hospital has positioned itself as a multidisciplinary medical facility with a long history of more than 200 years. Since its foundation, the hospital has been constantly developing and modernizin
Diagnosis of Zollinger–Ellison syndrome
26632
Diagnosis and conservative treatment of Zollinger–Ellison syndrome
9334
Surgical treatment of Zollinger–Ellison syndrome
19981

University Hospital Muenster

9.8/10
location_onGermany, Muenster

Department of Gastroenterology, Hepatology, Endocrinology, Diabetology and Infectology

According to the Focus magazine, the University Hospital Muenster ranks among the top German hospitals! The hospital belongs to the most prestigious medical institutions in Germany. The hospital is distinguished by a high professionalism of its doctors, state-of-the-art technological equipment and the availability of the most ad
Diagnosis of Zollinger–Ellison syndrome
23930
Diagnosis and conservative treatment of Zollinger–Ellison syndrome
8549
Surgical treatment of Zollinger–Ellison syndrome
22837
| from Booking Health GmbH

About the disease

Zollinger-Ellison syndrome is a disease that leads to the formation of tumors in the pancreas and duodenum. These tumors (gastrinomas) secrete a hormone (gastrin) that causes the stomach to produce too much acid, which can lead to peptic ulcers.

Someone suffering from Zollinger-Ellison syndrome may have one or several gastrinomas. According to WebMD, if a person has just one gastrinoma, there is a chance it is malignant. A single malignant gastrinoma can spread to other organs, making it extremely dangerous. People with Zollinger-Ellison syndrome may also develop tumors in the pituitary and parathyroid glands.

Zollinger-Ellison syndrome is generally considered to be a rare disorder. According to Medical News Today, this condition affects approximately one person in a million. It is more common among people aged 20-50, and slightly more prevalent in men. Although the exact cause of Zollinger-Ellison syndrome has not yet been identified, it is thought to be caused by a genetic predisposition or gene mutation. If a parent has Zollinger-Ellison syndrome, there is a 50% risk that the child will inherit this condition.

Symptoms

  • Abdominal pain
  • Diarrhea
  • Nausea
  • Weakness
  • Fatigue
  • Weight loss
  • Burning sensation in the abdomen

Diagnosis

  • During a general examination, the doctor will ask the patient about their family’s medical history whether they have suffered from any of the symptoms, listed above.
  • A blood test can establish whether gastrin levels are too high. This test may need to be repeated after some time, as the levels of gastrin may change.
  • Imaging tests, such as an endoscopy, MRI or CT scan, can determine whether there are any tumors in the pancreas or duodenum. These tests can also rule out other conditions, which could be causing similar symptoms.

Treatment

  • Conservative treatment, including medications that control the acidity in the stomach, is likely to be the first course of action.
  • Surgical resection, whereby tumors and peptic ulcers are removed, may also be necessary.
  • Patients of this disorder need to be examined on a regular basis, to prevent the development of new tumors or peptic ulcers.

Authors: Dr. Vadim ZhiliukDr. Sergey Pashchenko




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