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Insulinoma Treatment

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Best hospitals and doctors for insulinoma treatment abroad

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The selection of doctors and clinics is carried out on the basis of annual qualification reports. The main selection criterion is the number of operations or procedures performed. It takes into account experience, reputation in the medical society, the availability of quality certificates and high specialization in a certain field.

Cost for treatment

Diagnosis of insulinoma
 from  2292
Insulinoma treatment with partial pancreas resection
 from  18689
General therapeutic rehabilitation
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Academic Hospital Neuperlach Munich

9.8/10
location_onGermany, Munich

Department of Endocrinology, Diabetology, Angiology and Internal Medicine

The Neuperlach Clinic is a modern medical facility with a high level of service. The clinic has high-tech modern equipment, making it one of the best hospitals not only in Germany but also in Europe. There are comfortable single and double rooms with shower and toilet, TV, telephone and radio. The clinic has a dining room with a
Diagnosis of insulinoma
0

University Hospital of Ludwig Maximilian University of Munich

10/10
location_onGermany, Munich

Department of Endocrinology, Rheumatology and Nephrology

According to the Focus magazine, the University Hospital of Ludwig Maximilian University of Munich is regularly ranked among the best medical institutions in Germany! The hospital is the largest multidisciplinary medical facility, as well as a leading research and training center in Germany and Europe. The hospital is proud of i
Diagnosis of insulinoma
0
Insulinoma treatment with partial pancreas resection
0

Primus Super Speciality Hospital New Delhi

9/10
location_onIndia, New Delhi

Department of Endocrinology

The Primus Super Speciality Hospital New Delhi is a modern medical facility, which is distinguished by extremely high quality and standards of medical service. The hospital is located in the heart of New Delhi, in the capital of India. During its design and construction, the most advanced medical technologies from around the wor
Diagnosis of insulinoma
2496 help2316

University Hospital Carl Gustav Carus Dresden

9.1/10
location_onGermany, Dresden

Department of Endocrinology, Diabetology and Metabolic Disorders

According to the prestigious Focus magazine, the University Hospital Carl Gustav Carus Dresden is among the top three hospitals in Germany! The hospital is the embodiment of the standards of modern high-quality medicine. Since the hospital positions itself as a maximum care medical facility, it represents all medical fields. The
Diagnosis of insulinoma
0

University Hospital Frankfurt am Main

10/10
location_onGermany, Frankfurt am Main

Department of Gastroenterology, Hepatology, Pulmonology, Allergology, Endocrinology and Diabetology

According to the reputable Focus magazine, the University Hospital Frankfurt am Main ranks among the top German medical facilities! The hospital was founded in 1914 and today is a well-known German medical facility, which combines rich traditions and scientific innovations. A medical team of more than 6,500 employees cares about
Diagnosis of insulinoma
0

University Hospital Bonn

9.2/10
location_onGermany, Bonn

Department of Gastroenterology, Hepatology, Nephrology, Infectology, Endocrinology and Diabetology

According to the authoritative Focus magazine, the University Hospital Bonn ranks among the top ten medical facilities in Germany! The hospital was opened on January 1, 2001, although in fact it inherits the medical facility, which operated at the Faculty of Medicine of the University of Bonn. The hospital in Germany combin
Diagnosis of insulinoma
0

University Hospital Jena

8.9/10
location_onGermany, Jena

Department of Nephrology, Rheumatology, Osteology and Endocrinology

According to the prestigious Focus magazine, the University Hospital Jena regularly ranks among the top German medical facilities! The hospital has positioned itself as a multidisciplinary medical facility with a long history of more than 200 years. Since its foundation, the hospital has been constantly developing and modernizin
Diagnosis of insulinoma
0

University Hospital RWTH Aachen

8.7/10
location_onGermany, Aachen

Department of Gastroenterology, Metabolic Disorders and Internal Intensive Care

According to the prestigious Focus magazine, the University Hospital RWTH Aachen ranks among the top German hospitals! As a maximum care university medical facility, the hospital guarantees patients first-class medical services combined with a respectful and human attitude. The hospital integrates all the modern options for the
Diagnosis of insulinoma
0
Insulinoma treatment with partial pancreas resection
0

University Hospital Marburg UKGM

8.6/10
location_onGermany, Marburg

Department of Gastroenterology, Endocrinology, Metabolism and Clinical Infectology

The University Hospital Marburg UKGM offers patients modern diagnostics and comprehensive therapy at the international level. As a maximum care hospital, the medical facility specializes in all fields of modern medicine ranging from ophthalmology to traumatology and dentistry. The main areas of specialization of the hospital are
Diagnosis of insulinoma
0
Insulinoma treatment with partial pancreas resection
0

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of Nephrology, Rheumatology, Endocrinology and Diabetology

According to the prestigious Focus magazine, the University Hospital Halle (Saale) ranks among the top German medical facilities! The history of the hospital has more than 300 years, and during this time it managed to earn an excellent reputation not only in Germany, but throughout the world. The hospital positions itself as a s
Diagnosis of insulinoma
0

University Hospital Rechts der Isar Munich

9.8/10
location_onGermany, Munich

Department of Gastroenterology, Hepatology, Endocrinology, Diabetology and Infectology

According to the prestigious FOCUS magazine, the University Hospital Rechts der Isar Munich ranks among the Germany's top medical institutions! Founded in 1834, the hospital combines long traditions and the very latest achievements of modern medicine. The medical facility includes 33 specialized departments, 20 interdiscipli
Diagnosis of insulinoma
0
Insulinoma treatment with partial pancreas resection
0

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Department of Endocrinology and Metabolic Disorders

According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! The hospital is one of the largest and leading university medical complexes in Europe. The hospital in Germany provides modern diagnostics and treatment of patients, a
Diagnosis of insulinoma
0
Insulinoma treatment with partial pancreas resection
0

University Hospital Duesseldorf

9.5/10
location_onGermany, Duesseldorf

Department of Endocrinology and Diabetology

According to the authoritative Focus magazine, the University Hospital Duesseldorf ranks among the top Germany hospitals! The hospital is an excellent example of a combination of high-quality health care, research and teaching activities. With more than 50,000 inpatients and about 300,000 outpatients every year, the hospital is
Diagnosis of insulinoma
0

University Hospital Muenster

9.8/10
location_onGermany, Muenster

Department of Gastroenterology, Hepatology, Endocrinology, Diabetology and Infectology

According to the Focus magazine, the University Hospital Muenster ranks among the top German hospitals! The hospital belongs to the most prestigious medical institutions in Germany. The hospital is distinguished by a high professionalism of its doctors, state-of-the-art technological equipment and the availability of the most ad
Diagnosis of insulinoma
0

University Hospital Giessen UKGM

9.5/10
location_onGermany, Giessen

Department of Endocrinology, Diabetology, Metabolic Disorders and Nutritional Medicine

The University Hospital Giessen UKGM positions itself as an ultramodern medical facility with outstanding quality of medical care. The hospital presents almost all areas of medicine, ranging from ophthalmology to traumatology and dentistry. The priorities of the hospital’s activities include surgery, neurosurgery, oncology
Diagnosis of insulinoma
0

University Hospital Essen

9.6/10
location_onGermany, Essen

Department of Endocrinology and Metabolic Disorders

According to the authoritative Focus magazine the University Hospital Essen ranks among the top German hospitals! With 27 specialized departments and 24 institutes, the hospital in Germany is a maximum care medical facility. The hospital has 1,300 beds for inpatient treatment. A highly qualified medical team of more than 6,000 e
Diagnosis of insulinoma
0

About the disease

Insulinoma is a benign tumor of the pancreas which originates in the beta cells responsible for insulin secretion. Insulinoma is the rarest cancer of endocrinal system. It also never metastases into other organs. Insulinoma derives from beta cells and secrets insulin. If the person has insulinoma, the level of blood glucose in his blood circulation is very low, because the secretion of the insulin does not function properly. If the pancreas generates too much insulin, a person may develop insulinoma. Pancreas is located in the abdomen and it produces hormones among which insulin is one of the most vital as it reduces sugar level in blood. If the level of sugar becomes too low or too high, the pancreas stops producing insulin. In case the pancreas produces too much insulin which is not proportional to the level of blood sugar, insulinoma may develop.    

The most well-known insulinoma cause is hypoglycemia, when blood sugar is low. If the case of hypoglycemia is not severe, the person feels anxiety, dizziness and hunger. If hypoglycemia is progressed, it may result in much more serious outcomes, such as coma or death.

Another insulinoma cause is the genetic predisposition. Usually people may develop insulinoma after 40 years old, because children have cells in the pancreas, which can release the excessive amount of insulin and regulate its level. Almost all insulinomas are benign, that`s why they are not as dangerous as malignant tumors.

Symptoms

  • Seizures
  • Changes in behaviour
  • Anxiety attacks
  • Weight gain
  • Dizziness
  • Sweating
  • Constant hunger
  • Headache
  • Anger
  • Speech disorder

Usually there are no symptoms during the initial phase of tumor development. After it is bigger than 50 mm, hypoglycemia symptoms become apparent. Usually it includes increased appetite and development of obesity. Even after food consumption, he still feels hunger and begins to overeat systematically. Episodes of sudden hunger can occur even at night when a person suddenly wakes up and has an urgent need to eat something. As a result the central nervous system violates its functions and a person may have an acute hypoglycemic attack. Usually the attack begins in the morning when the person did not eat for several hours. During that period glucose level starts to drop by several levels. If the hypoglycemic attack is mild, person feels only certain neurological disorders, which includes weakness and headache. The person also feels dizzy, cannot concentrate, stand up for a long time or speak in a prolonged manner, he is usually very sleepy and needs something sweet to eat.

If hypoglycemic attack is more severe, the person has absolutely opposite insulinoma symptoms. He suddenly becomes over excited and agitated, feels restlessness and euphoria, which can even result in colorful hallucinations. Euphoria may suddenly turn into unmotivated aggression, when the person starts to scream or cry without any obvious reason. Hypoglycemic attack is in most cases accompanied by tremor, cold sweat and tachycardia. If the attack progresses, the person may get into coma. The attack is usually cured with intravenous administration of glucose. After the return of consciousness patients usually do not remember anything what happened. They become very tranquil and relaxed. The attack can cause not only coma, but also a heart attack, because the heart valves during the seizure stop working properly.  In that case the patient requires immediate medical help.

Diagnosis

The diagnosis of insulinoma is usually carried out during blood tests. The blood test determines the level of glucose and insulin in the blood and if the levels are either too high or too low the patient undergoes the magnetic resonance scan or the ultrasound too see if there is tumor. If the patient was diagnosed with hypoglycemia, he also needs to undergo complex laboratory tests to understand the reason of low blood sugar level. Usually the patient needs to go through starvation to create a hypoglycemic state and to analyze the reaction of the body to it.

Sometimes doctors small doses of insulin can be injected to check body reaction.. The level of insulin in healthy people is significantly lower for those who have tumor and that`s why the insulin is introduced into blood to maintain the proportional ratio between glucose and sugar.

In some cases it is very difficult to distinguish insulinoma from the moderate case of hypoglycemia. Usually hypoglycemia is caused by alcohol or grugs abuse, that`s why the doctor always asks the patient about his drinking habits and the names of drugs he takes. Insulinoma symptoms apart from everyting resemble the symptoms of adrenal cancer as well. 

Treatment

The treatment of insulinoma usually requires surgical resection. In most cases surgery involves resection of the affected part of the pancreas. Surgery is considered to be successful, if the level of glucose and insulin normalizes. Nevertheless, there may be such post-operative complications as the necrosis of the pancreas which means that the cells of the pancreas become dead. Surgery can also result in peritonitis and in that case the patient requires another operation.

If insulinoma is inoperable which may happen if its size is too big or location inaccessible, doctors apply conservative treatment. Thus type of treatment applies drugs that can prevent the development of hypoglycemia by introducing adrenaline into the body. In the initial stages of conservative treatment the patient is usually recommended to intake high amounts of carbohydrates.

If insulinoma is malignant, in addition to surgery doctors may administrate several courses of chemotherapy. Radiofrequency intervention is usually not applied for the insulinoma treatment.

People who have underwent surgery later need to be regularly examined by neurologist and an endocrinologist. They also need to have their blood test taken every month to screen the level of glucose and insulin in blood. Patients usually have to balance their diet, which should include vegetables and fruits. They must also avoid sweets and fatty food.




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