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Treatment of Parkinsons disease | ️Best clinics, Types of treatments, Treatment costs | ️ Booking Health

Diagnostic and treatment of Parkinsons disease

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Best hospitals and doctors for parkinsons disease treatment abroad

Leading hospitals

Cost for treatment

Parkinson Disease Diagnostics
1726
Diagnosis and conservative treatment of parkinsons disease
5476.82
Diagnosis of Parkinson's disease before deep brain stimulation (DBS) and implanted of neurostimulator
4252
Stem cell therapy for Parkinsons disease
20550
Surgical treatment of parkinsons disease by pallidotomy
7620.16
Treatment of Parkinsons disease with deep brain stimulation (DBS) and implantation of neurostimulator
30635.14
Neurological rehabilitation Phase C
2000
According to the reputable Focus magazine, the Hospital Nordwest Frankfurt am Main ranks among the top German medical facilities! The hospital has a reputation of a modern multidisciplinary medical center with excellent quality of services. The medical complex is an academic hospital of the Goethe University Frankfurt, thanks t
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The Catholic Clinic Koblenz-Montabaur is a modern medical facility with an excellent reputation in Germany and abroad. The medical center is an academic clinic of the University Hospital Mainz, which gives patients the opportunity to take advantage of scientific advances and innovative treatments. The clinic has the widest possi
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The Park-Clinic Weissensee Berlin is a progressive medical facility with the highest standards of medical care. The medical facility is an academic hospital of the Charite University Hospital Berlin, thanks to which the specialists have access to all medical innovations. The clinic was opened on April 1, 1997, on the former Weis
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The St. Lukas Clinic Solingen provides high-quality medical services at an international level, while the humane values ​​of Catholicism are the fundamental principle of the work of the medical staff. The clinic has been successfully practicing for over 60 years, and during this time it has managed to save thousands of human liv
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According to the prestigious Focus magazine, the Hospital Harlaching Munich ranks among the top 20 medical centers in Bavaria, and is also one of the 100 best hospitals in Germany! The medical complex provides top-class medical care, which meets modern European standards. The medical facility is an Academic Hospital of the Ludwi
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Sana Hospital Duisburg
Sana Hospital Duisburg
Overall rating9.5 / 10
The Sana Hospital Duisburg is a maximum care medical center with 678 beds and 17 specialized departments. With the very latest innovations and high quality patient care, the clinic works for the benefit of a person and their health. The hospital ranks among the leading clinics in the region. In 2013, the hospital
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The Hirslanden Clinic Meggen is a modern multidisciplinary medical facility in Switzerland, where the patient receives top-class medical care according to his individual needs and wishes. Since 2014, the clinic has been part of the prestigious Hirslanden Private Hospital Group, which has an excellent reputation in Switzerland an
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Prof. Christian Franke Neurology Clinic Munich is a highly specialized medical facility that treats patients with diseases of the nervous system. The clinic has an excellent medical and technical basis for providing professional medical care in accordance with international standards. A competent team of neurologists and nursing
Asan Medical Center is Korea’s largest medical institution, with 1,600 physicians and surgeons, 3,100 nurses, 2,680 beds, and 67 operating rooms, occupying more than four million square feet (about 371,600 square meters). A typical day at AMC sees 2,500 inpatients and 10,000 outpatients treated. The treatment of heart dise
The Vivantes Auguste-Victoria Hospital, has special expertise and received international recognition in the field of Urology, especially in the treatment of prostate cancer and also Oncology, Neurology, Cardiology and other directions. The possibilities of urological treatment include robot-assisted surgeries using the Da Vinci
An academic clinic of the university medical complex Charité, the Vivantes Humboldt Hospital is one of the largest specialized medical institutions in Berlin. The hospital is famous for its impeccable reputation in the field of traumatology, orthopedics, urology and gynecology, as well as treatment of oncological diseases
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About the disease

Parkinson’s disease is a chronic, progressive brain disease, first described in the beginning of nineteenth century by the English doctor-physician John Parkinson. It is also known as a tremor disease. Patients with Parkinson’s disease often suffer from uncontrolled limb tremor, muscles stiffness, impaired joint coordination and problem with speech. These signs usually develop after age of 55, although there are cases of Parkinson’s disease under the age of 55 years.

Tremor develops as a result of damage or destruction of neurons located in the black substance of a brain and accumulation of alpha-synuclein inside them. In healthy brain these nerve cells produce neurotransmitter dopamine. The function of dopamine is to ensure the normal work of mesocortical (responsible for motivation and emotional reactions), mesolimbic (responsible for feelings of pleasure, reward and desire) and nigrostriatal pathway (responsible for motor activity). In Parkinson’s disease the reduced production of dopamine interferes with the normal transmission of nerve impulses.

Several medications taken for a long time at high doses can cause Parkinson’s disease. These includes drugs for treatment of certain mental disorders, as well as anti-nausea medications, such as metoclopramide. The antiepileptic valproic acid may also cause some of the most well-known symptoms of Parkinson's disease. Parkinson’s disease may also be caused by an infectious or traumatic brain injury.

Symptoms

  • Tremor of hands
  • Light finger shaking
  • Minor speech disorders
  • Devastating mood
  • Loss of vital strength
  • Insomnia

Parkinson’s disease is progressive, its symptoms aggravate and worsen over time. It eventually leads to disability and total loss of motion capacity.

Tremor often starts with a slight trembling of the fingers or of even individual fingertips. In some cases tremor is accompanied by uneven movement of middle finger and thumb which looks like a person is rolling invisible pills. These symptoms may appear with other disorders of nervous system, such as discoordination. Shaking is particularly evident during the "pill rolling syndrome" which occurs mostly when the patient is stressed and devastated about something. Although tremor of limbs and joints causes considerable further inconvenience, it does not end in a total loss of vital capacity. Many patients with tremor disease suffer only from a little shaking.

Diagnosis

  • There are no specific diagnostic tests for Parkinson’s disease. That is why doctor starts examination from medical history checking and excluding concomitant pathology of the brain. Then doctor proceeds to neurological examination, including cognitive tests.
  • Transcranial sonography is the ultrasound technique that allows to assess the state of dopamine-producing cells.
  • MRI allows to exclude not connected with Parkinson’s disease brain injuries that can also cause tremor.
  • PET-scan is the most informative examination, as it reflects the functional activity of the brain cells. PET-scan can reveal the earliest stages of the disease.

Treatment

The treatment program should be individualized for each patient. The rationally selected regimen will allow to achieve good results for a long time. 

  • Lifestyle modification. Aerobic exercises and balance training will improve ability to walk and somewhat reduce tremor.
  • Drugs intake. The most effective in patients with Parkinson’s disease medication is carbidopa-levodopa. It replaces deficiency of dopamine and restores normal work of nervous pathways. Dopamine agonists are also used. This type of drugs has different from the dopamine structure, but similar effects. Anticholinergics will help to cope with tremor, this is a symptomatic treatment.
  • Deep brain stimulation (DBS) with implanted neurostimulator is the modern treatment technique, which uses neurostimulator to send electrical impulses to specific areas in the brain responsible for movement. This procedure can improve tremor and other manifestations of dyskinesia.
  • Pallidotomy is a surgery during which a surgeon removes the overactive part of the brain, which lessens the tremor and eliminates rigidity.

Authors: Dr. Nadezhda Ivanisova, Dr. Sergey Pashchenko