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Hyperthermic Intraperitoneal Chemotherapy | Best Hospitals | Prices | Clinics | Booking Health

Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

HIPEC procedure | Highly qualified medical professionals and best hospitals for hipec | Clinics | Surgery Cost | Send request to the hospital

Best hospitals and doctors for Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

Leading hospitals

Cost for treatment

Multimodality treatment of appendix cancer with cytoreductive surgery and HIPEC
51827
Multimodality treatment of colon cancer with cytoreductive surgery and HIPEC
51859
Multimodality treatment of duodenal cancer with cytoreductive surgery and HIPEC
51956
Multimodality treatment of gastrointestinal carcinoid tumors with cytoreductive surgery and HIPEC
51948
Multimodality treatment of mesothelioma with cytoreductive surgery and HIPEC
39790
Multimodality treatment of ovarian cancer with cytoreductive surgery and HIPEC
23949
Multimodality treatment of peritoneal carcinomatosis with cytoreductive surgery and HIPEC
44876.6
Multimodality treatment of pseudomyxoma peritonei with cytoreductive surgery and HIPEC
51935
Multimodality treatment of rectal cancer with cytoreductive surgery and HIPEC
52123
Multimodality treatment of stomach cancer with cytoreductive surgery and HIPEC
51875
General therapeutic rehabilitation
0.00
HELIOS Clinic Krefeld
HELIOS Clinic Krefeld
Overall rating9.7 / 10
Founded in 2014, the HELIOS Clinic Krefeld is one of the most modern medical facilities in Germany today. A team of highly qualified specialists, innovative medical equipment and comfortable accommodation conditions – the clinic has everything to make the treatment run smoothly and efficiently. Having crossed the threshold
According to the Focus magazine, the University Hospital of Ludwig Maximilian University of Munich is regularly ranked among the best medical institutions in Germany! The hospital is the largest multidisciplinary medical facility, as well as a leading research and training center in Germany and Europe. The hospital is proud of i
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University Hospital Ulm
University Hospital Ulm
Overall rating8.7 / 10
The University Hospital Ulm is an advanced medical complex that provides patients with high-class medical care using the very latest scientific achievements. The medical facility has been performing successful clinical activities for more than 40 years and has long earned an excellent reputation throughout Europe. The hospital r
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According to the reputable Focus magazine, the University Hospital Carl Gustav Carus Dresden ranks among the top five German hospitals! The hospital is the benchmark for modern high-quality medicine. Positioning itself as a maximum care medical facility, the hospital represents all medical fields. There are 26 specialized depart
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According to the reputable Focus magazine, the University Hospital Frankfurt am Main ranks among the top German medical facilities! The hospital was founded in 1914 and today is a well-known German medical facility, which combines rich traditions and scientific innovations. A medical team of more than 6,500 employees cares about
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According to the prestigious Focus magazine, the University Hospital RWTH Aachen ranks among the top German hospitals! As a maximum care university medical facility, the hospital guarantees patients first-class medical services combined with a respectful and human attitude. The hospital integrates all the modern options for the
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The University Hospital Marburg UKGM offers patients modern diagnostics and comprehensive therapy at the international level. As a maximum care hospital, the medical facility specializes in all fields of modern medicine ranging from ophthalmology to traumatology and dentistry. The main areas of specialization of the hospital are
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According to the prestigious Focus magazine, the University Hospital Halle (Saale) ranks among the top German medical facilities! The history of the hospital has more than 300 years, and during this time it managed to earn an excellent reputation not only in Germany, but throughout the world. The hospital positions itself as a s
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University Hospital Jena
University Hospital Jena
Overall rating8.9 / 10
According to the prestigious Focus magazine, the University Hospital Jena regularly ranks among the top German medical facilities! The hospital has positioned itself as a multidisciplinary medical facility with a long history of more than 200 years. Since its foundation, the hospital has been constantly developing and modernizin
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According to Focus magazine, the University Hospital Heidelberg ranks among the top five hospitals in Germany! The hospital is one of the most advanced and reputable medical institutions not only in Germany, but throughout Europe. There are more than 43 specialized departments and 13 medical institutes, which cover all fields of
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According to the Focus magazine, the University Hospital Hamburg-Eppendorf ranks among the top ten hospitals in Germany! Since its foundation in 1889, the hospital has taken a leading position in the European medical arena and still occupies it until today. A highly competent medical team of more than 11,000 employees takes care
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According to the Focus magazine in 2019, the University Hospital Würzburg ranks among the top national German hospitals! The hospital is one of the oldest medical facilities in Germany. The centuries-old traditions of first-class treatment are combined with the very latest achievements of modern evidence-based medicine and
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According to the prestigious medical publication Focus, the University Hospital Tuebingen ranks among the top five German hospitals! The hospital was founded in 1805, therefore it is proud of its long history, unique experience, and outstanding achievements in the field of medical care, as well as research and teaching activitie
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According to the Focus magazine, the University Hospital Muenster ranks among the top German hospitals! The hospital belongs to the most prestigious medical institutions in Germany. The hospital is distinguished by a high professionalism of its doctors, state-of-the-art technological equipment and the availability of the most ad
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Peritoneal cancer, which affects the membrane lining the abdominal cavity, causes multiple foci of malignant neoplasms. Doctors do not always manage to find and remove them all. Therefore, the risk of relapse after surgical treatment remains high. To reduce it, doctors use HIPEC – hyperthermic intraperitoneal chemotherapy.

Content

  1. What is Peritoneal Cancer?
  2. What is HIPEC Surgery?
  3. How is the Procedure Performed?
  4. Where Can I Get treatment?
  5. Treatment Organization

HIPEC, hyperthermic intraperitoneal chemotherapy, is the flushing of the abdomen with a concentrated solution of chemo drugs to destroy cancerous foci on the peritoneum.

The procedure is performed after surgical treatment of cancer to reduce the risk of recurrence.

The preparation for the therapy takes 6-9 hours, during which time no food or medication is allowed. Before that, the patient undergoes an examination for 1-2 days.

The cost of treatment ranges from 45 to 60,000 euros. It is influenced by the type of oncology, the level of the clinic, age and general condition of the patient. On the Booking Health website you will find a list of clinics with current prices for treatment.

Please leave a request on the Booking Health website and attach your medical reports. A medical coordinator will contact you within 24 hours and you will discuss all your questions.

What is Peritoneal Cancer?

 

Peritoneal cancer (peritoneal carcinomatosis) is a variant of progressive, malignant abdominal tumours, which cause multiple metastases on the serous membrane of the abdominal cavity. It develops in every third patient with tumours of the pancreas, stomach and appendix. This complication develops in 10% of patients who suffer from colorectal cancer. Other localisations of the primary tumour which leads to peritoneal cancer include:

  • ovaries;
  • endometrium;
  • fallopian tubes;
  • liver;
  • gallbladder;
  • peritoneum (peritoneal mesothelioma).

There are four stages of the disease. The first stage is characterized by small metastases of up to 5mm in size. All of them are located in one area. At the second stage, the tumours are located diffusely throughout the abdomen. At the third stage, they are from 5 to 20mm in size, whilst at the fourth stage the size of foci may reach over 20mm.

What is HIPEC Surgery?

 

Surgery remains the main method used to treat patients with abdominal neoplasms. The main tumour is removed. In a case of peritoneal carcinomatosis and the spread of metastases to other organs, a cytoreductive surgery may be performed. This involves the removal of all visible tumour nodes. For this purpose, doctors resect several organs at once.

Nonetheless, the doctors cannot always detect all of the metastatic foci. In addition, many of the foci have microscopic dimensions. Therefore, the probability of cancer recurrence after cytoreductive surgery still remains high. HIPEC (hyperthermic intraperitoneal chemotherapy) serves to reduce this risk. It is used directly during the surgical intervention.

HIPEC surgery allows for the destruction of the remaining foci of tumour cells. The procedure aims to completely eradicate the tumour. If successful, a complete recovery is possible for the patient. However, even if the cancer cannot be cured, HIPEC can significantly increase life expectancy. Approximately two thirds of patients live 5 years or longer after having HIPEC surgery. The procedure also significantly decreases the severity of the symptoms of the disease.

How is the Procedure Performed?

 

HIPEC is conducted immediately after cytoreduction, that is, after the resection of organs and the destruction of all visible tumour foci.

The doctors place a drainage tube to provide outflow and inflow. Thermal sensors are used to monitor the intra-abdominal temperature. They are located in different parts of the peritoneal cavity. The abdominal skin is sutured with a temporary suture.

The next step is abdominal irrigation with a chemotherapy solution, heated to 42.5 celsius. The total perfusion is about 5 liters. The average flow rate is 700ml per minute. The perfusion is performed using a special apparatus. The average duration of the procedure is an hour and a half. Then, the doctors make a revision of the abdominal cavity. This drains and the surgical wound is sutured.

When treating peritoneal cancer, HIPEC has significant advantages over systemic chemotherapy, where drugs are taken orally or administered intravenously. The advantages are as follows:

  • pharmacokinetics – intracavitary administration of drugs can significantly increase the dose;
  • hyperthermia – heating of the drug makes it possible to increase the selective antitumor effect, increase the ablastic effect and increase the depth of penetration of the drug into the tumour tissues.

 

Where Can I Get treatment?

 

To treat cancer, patients often go to Germany.  This country achieves phenomenal successes in the fight against malignant tumours.  It successfully performs cytoreductive surgical procedures and uses intraperitoneal chemotherapy. The cost of HIPEC ranges from €23.949 to €92.474 and depends on the type of cancer, the extent to which it has spread and the level of the hospital. Here is a list of the best clinics abroad, where patients can undergo treatment:

  • Helios Clinic Krefeld. Here, The Department of Abdominal and Minimally Invasive Surgery is responsible for performing cytoreductive surgery with intraperitoneal chemotherapy. The department shows excellent results in the treatment of abdominal cancers. The cost of treatment is about 40 thousand euros.
  • Charite University Hospital. This is one of the most reputable medical institutions in Europe. The surgery combined with hyperthermic chemotherapy is performed in the Department of General, Abdominal and Vascular Surgery. Cytoreductive surgery for oncological diseases remains one of the main department’s work focuses. The cost of treatment here reaches 60 thousand euros.
  • University Hospital of Ludwig Maximilian University. This hospital is included in the ranking of the top medical facilities specializing in the treatment of abdominal cancers. The cytoreductive surgical procedures with hyperthermic chemotherapy are performed in the Department of General, Abdominal and Transplant Surgery. The treatment cost is 45 thousand euros.

Treatment Organization

 

If you have symptoms of cancer, you can become a patient at one of Germany’s clinics. Booking Health will help you to organize your treatment in one of the best clinics abroad. Our services and benefits include:

  • Selecting the best clinic specializing in cytoreductive surgery with hyperthermic intraperitoneal chemotherapy.
  • A treatment cost reduction of up to 50% by eliminating coefficients for foreign patients.
  • The possibility of undergoing treatment at a date convenient for you.
  • An establishment of communication with doctors and the administration team before the start of treatment and after the end of the program.
  • The preparation of a treatment program without repeating previously completed examinations.
  • Monitoring of the program at all its stages.
  • Funds management and the return of any unspent funds.
  • The organization of additional examinations.
  • Assistance when purchasing and the transmission of medicines.

Booking Health will provide you with a high level of service. We will booka hotel and airline tickets for you, help you to complete the necessary paperwork, meet you at the airport and take you to the clinic by car.

 

Authors: 

The article was edited by medical experts, board-certified doctors Dr. Nadezhda Ivanisova and Dr. Sergey Pashchenko. For the treatment of the conditions referred to in the article, you must consult a doctor; the information in the article is not intended for self-medication!

 

Sources:

National Center for Biotechnology

Cancer Research Institute

American Cancer Society