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Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

Due to the difficulties associated with the organization of treatment in Turkey, Switzerland, South Korea and India, we are not currently processing requests to these regions.

If you are interested in treatment in Germany, please leave a request and our specialists will contact you as soon as possible.

 

Cost for treatment

Multimodality treatment of appendix cancer with cytoreductive surgery and HIPEC
51405.3
Multimodality treatment of colon cancer with cytoreductive surgery and HIPEC
51461.85
Multimodality treatment of duodenal cancer with cytoreductive surgery and HIPEC
51328.45

HELIOS Clinic Krefeld

9.7/10
location_onGermany, Krefeld

Department of General, Abdominal and Minimally Invasive Surgery

Founded in 2014, the HELIOS Clinic Krefeld is one of the most modern medical facilities in Germany today. A team of highly qualified specialists, innovative medical equipment and comfortable accommodation conditions – the clinic has everything to make the treatment run smoothly and efficiently. Having crossed the threshold
Multimodality treatment of appendix cancer with cytoreductive surgery and HIPEC
60153.15
Multimodality treatment of colon cancer with cytoreductive surgery and HIPEC
60196.65
Multimodality treatment of duodenal cancer with cytoreductive surgery and HIPEC
60066.15

University Hospital of Ludwig Maximilian University of Munich

10/10
location_onGermany, Munich

Department of General, Abdominal and Transplant Surgery

According to the Focus magazine, the University Hospital of Ludwig Maximilian University of Munich is regularly ranked among the best medical institutions in Germany! The hospital is the largest multidisciplinary medical facility, as well as a leading research and training center in Germany and Europe. The hospital is proud of i
Multimodality treatment of appendix cancer with cytoreductive surgery and HIPEC
68464.55
Multimodality treatment of colon cancer with cytoreductive surgery and HIPEC
68447.15
Multimodality treatment of duodenal cancer with cytoreductive surgery and HIPEC
68566.05

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Department of General, Abdominal and Vascular Surgery

According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! The hospital is one of the largest and leading university medical complexes in Europe. The hospital in Germany provides modern diagnostics and treatment of patients, a
Multimodality treatment of appendix cancer with cytoreductive surgery and HIPEC
93832.3
Multimodality treatment of colon cancer with cytoreductive surgery and HIPEC
94544.25
Multimodality treatment of duodenal cancer with cytoreductive surgery and HIPEC
93749.65

University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of General and Abdominal Surgery

The University Hospital Ulm started its activities 35 years ago and during this time it has become one of the most prestigious medical institutions in Europe. The hospital is famous for its numerous discoveries and the world-class achievements in medicine and pharmaceuticals. The medical facility has 29 specialized departments a
Multimodality treatment of appendix cancer with cytoreductive surgery and HIPEC
64624.95
Multimodality treatment of colon cancer with cytoreductive surgery and HIPEC
64137.75
Multimodality treatment of duodenal cancer with cytoreductive surgery and HIPEC
64616.25

University Hospital Carl Gustav Carus Dresden

9.1/10
location_onGermany, Dresden

Department of Abdominal and Colorectal Surgery, Hepatobiliary Surgery, Hernia Surgery, Bariatric Surgery, Endocrine Surgery, Thoracic and Vascular Surgery

According to the reputable Focus magazine, the University Hospital Carl Gustav Carus Dresden ranks among the top five German hospitals! The hospital is the benchmark for modern high-quality medicine. Positioning itself as a maximum care medical facility, the hospital represents all medical fields. There are 26 specialized depart
Multimodality treatment of appendix cancer with cytoreductive surgery and HIPEC
81781.35
Multimodality treatment of colon cancer with cytoreductive surgery and HIPEC
81640.7
Multimodality treatment of duodenal cancer with cytoreductive surgery and HIPEC
81739.3

University Hospital Frankfurt am Main

10/10
location_onGermany, Frankfurt am Main

Department of General and Abdominal Surgery

According to the reputable Focus magazine, the University Hospital Frankfurt am Main ranks among the top German medical facilities! The hospital was founded in 1914 and today is a well-known German medical facility, which combines rich traditions and scientific innovations. A medical team of more than 6,500 employees cares about
Multimodality treatment of appendix cancer with cytoreductive surgery and HIPEC
60115.45
Multimodality treatment of colon cancer with cytoreductive surgery and HIPEC
59824
Multimodality treatment of duodenal cancer with cytoreductive surgery and HIPEC
59889.25

University Hospital RWTH Aachen

9.2/10
location_onGermany, Aachen

Department of Adult and Pediatric General, Abdominal, Transplant Surgery

According to the prestigious Focus magazine, the University Hospital RWTH Aachen ranks among the top German hospitals! As a maximum care university medical facility, the hospital guarantees patients first-class medical services combined with a respectful and human attitude. The hospital integrates all the modern options for the
Multimodality treatment of appendix cancer with cytoreductive surgery and HIPEC
68228.2
Multimodality treatment of colon cancer with cytoreductive surgery and HIPEC
68441.35
Multimodality treatment of duodenal cancer with cytoreductive surgery and HIPEC
68551.55

University Hospital Marburg UKGM

8.6/10
location_onGermany, Marburg

Department of Abdominal, Thoracic and Vascular Surgery

The University Hospital Marburg UKGM offers patients modern diagnostics and comprehensive therapy at the international level. As a maximum care hospital, the medical facility specializes in all fields of modern medicine ranging from ophthalmology to traumatology and dentistry. The main areas of specialization of the hospital are
Multimodality treatment of appendix cancer with cytoreductive surgery and HIPEC
55617.55
Multimodality treatment of colon cancer with cytoreductive surgery and HIPEC
55991.65
Multimodality treatment of duodenal cancer with cytoreductive surgery and HIPEC
55460.95

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of General, Abdominal, Vascular and Endocrine Surgery

According to the prestigious Focus magazine, the University Hospital Halle (Saale) ranks among the top German medical facilities! The history of the hospital has more than 300 years, and during this time it managed to earn an excellent reputation not only in Germany, but throughout the world. The hospital positions itself as a s
Multimodality treatment of appendix cancer with cytoreductive surgery and HIPEC
59976.25
Multimodality treatment of colon cancer with cytoreductive surgery and HIPEC
60102.4
Multimodality treatment of duodenal cancer with cytoreductive surgery and HIPEC
59974.8

University Hospital Jena

8.9/10
location_onGermany, Jena

Department of General, Abdominal and Vascular Surgery

According to the prestigious Focus magazine, the University Hospital Jena regularly ranks among the top German medical facilities! The hospital has positioned itself as a multidisciplinary medical facility with a long history of more than 200 years. Since its foundation, the hospital has been constantly developing and modernizin
Multimodality treatment of appendix cancer with cytoreductive surgery and HIPEC
51405.3
Multimodality treatment of colon cancer with cytoreductive surgery and HIPEC
51461.85
Multimodality treatment of duodenal cancer with cytoreductive surgery and HIPEC
51328.45

University Hospital Heidelberg

9.8/10
location_onGermany, Heidelberg

Department of General, Abdominal and Transplant Surgery

According to Focus magazine, the University Hospital Heidelberg ranks among the top five hospitals in Germany! The hospital is one of the most advanced and reputable medical institutions not only in Germany, but throughout Europe. There are more than 43 specialized departments and 13 medical institutes, which cover all fields of
Multimodality treatment of appendix cancer with cytoreductive surgery and HIPEC
0
Multimodality treatment of colon cancer with cytoreductive surgery and HIPEC
0
Multimodality treatment of duodenal cancer with cytoreductive surgery and HIPEC
0

University Hospital Hamburg-Eppendorf

9.2/10
location_onGermany, Hamburg

Department of General, Abdominal and Thoracic Surgery

According to the Focus magazine, the University Hospital Hamburg-Eppendorf ranks among the top ten hospitals in Germany! Since its foundation in 1889, the hospital has taken a leading position in the European medical arena and still occupies it until today. A highly competent medical team of more than 11,000 employees takes care
Multimodality treatment of appendix cancer with cytoreductive surgery and HIPEC
81587.05
Multimodality treatment of colon cancer with cytoreductive surgery and HIPEC
81418.85
Multimodality treatment of duodenal cancer with cytoreductive surgery and HIPEC
81160.75

University Hospital Würzburg

9.2/10
location_onGermany, Würzburg

Department of General, Abdominal, Transplant, Vascular and Pediatric Surgery

According to the Focus magazine in 2019, the University Hospital Würzburg ranks among the top national German hospitals! The hospital is one of the oldest medical facilities in Germany. The centuries-old traditions of first-class treatment are combined with the very latest achievements of modern evidence-based medicine and
Multimodality treatment of appendix cancer with cytoreductive surgery and HIPEC
60056
Multimodality treatment of colon cancer with cytoreductive surgery and HIPEC
60216.95
Multimodality treatment of duodenal cancer with cytoreductive surgery and HIPEC
60493.9

University Hospital Tuebingen

9.2/10
location_onGermany, Tuebingen

Department of General, Abdominal, Adult and Pediatric Transplant Surgery

According to the prestigious medical publication Focus, the University Hospital Tuebingen ranks among the top five German hospitals! The hospital was founded in 1805, therefore it is proud of its long history, unique experience, and outstanding achievements in the field of medical care, as well as research and teaching activitie
Multimodality treatment of appendix cancer with cytoreductive surgery and HIPEC
64030.45
Multimodality treatment of colon cancer with cytoreductive surgery and HIPEC
64658.3
Multimodality treatment of duodenal cancer with cytoreductive surgery and HIPEC
63952.15

University Hospital Rechts der Isar Munich

9.8/10
location_onGermany, Munich

Department of Adult and Pediatric General, Abdominal, Hepatobiliary, Endocrine, Thoracic and Hernia Surgery

The University Hospital Rechts der Isar Munich was founded in 1834. It combines long traditions with the very latest advances in modern medicine. The medical facility includes 33 specialized departments and 20 interdisciplinary centers, where patients can receive top-class medical care in all medical fields. The hospital annuall
Multimodality treatment of appendix cancer with cytoreductive surgery and HIPEC
68299.25
Multimodality treatment of colon cancer with cytoreductive surgery and HIPEC
68355.8
Multimodality treatment of duodenal cancer with cytoreductive surgery and HIPEC
68496.45

University Hospital Muenster

9.8/10
location_onGermany, Muenster

Department of General, Abdominal and Transplant Surgery

According to the Focus magazine, the University Hospital Muenster ranks among the top German hospitals! The hospital belongs to the most prestigious medical institutions in Germany. The hospital is distinguished by a high professionalism of its doctors, state-of-the-art technological equipment and the availability of the most ad
Multimodality treatment of appendix cancer with cytoreductive surgery and HIPEC
59835.6
Multimodality treatment of colon cancer with cytoreductive surgery and HIPEC
60276.4
Multimodality treatment of duodenal cancer with cytoreductive surgery and HIPEC
60070.5
| from Booking Health GmbH

Peritoneal cancer, which affects the membrane lining the abdominal cavity, causes multiple foci of malignant neoplasms. Doctors do not always manage to find and remove them all. Therefore, the risk of relapse after surgical treatment remains high. To reduce it, doctors use HIPEC – hyperthermic intraperitoneal chemotherapy.

Content

  1. What is Peritoneal Cancer?
  2. What is HIPEC Surgery?
  3. How is the Procedure Performed?
  4. Where Can I Get treatment?
  5. Treatment Organization

What is Peritoneal Cancer?

 

Peritoneal cancer (peritoneal carcinomatosis) is a variant of progressive, malignant abdominal tumours, which cause multiple metastases on the serous membrane of the abdominal cavity. It develops in every third patient with tumours of the pancreas, stomach and appendix. This complication develops in 10% of patients who suffer from colorectal cancer. Other localisations of the primary tumour which leads to peritoneal cancer include:

  • ovaries;
  • endometrium;
  • fallopian tubes;
  • liver;
  • gallbladder;
  • peritoneum (peritoneal mesothelioma).

There are four stages of the disease. The first stage is characterized by small metastases of up to 5mm in size. All of them are located in one area. At the second stage, the tumours are located diffusely throughout the abdomen. At the third stage, they are from 5 to 20mm in size, whilst at the fourth stage the size of foci may reach over 20mm.

What is HIPEC Surgery?

 

Surgery remains the main method used to treat patients with abdominal neoplasms. The main tumour is removed. In a case of peritoneal carcinomatosis and the spread of metastases to other organs, a cytoreductive surgery may be performed. This involves the removal of all visible tumour nodes. For this purpose, doctors resect several organs at once.

Nonetheless, the doctors cannot always detect all of the metastatic foci. In addition, many of the foci have microscopic dimensions. Therefore, the probability of cancer recurrence after cytoreductive surgery still remains high. HIPEC (hyperthermic intraperitoneal chemotherapy) serves to reduce this risk. It is used directly during the surgical intervention.

HIPEC surgery allows for the destruction of the remaining foci of tumour cells. The procedure aims to completely eradicate the tumour. If successful, a complete recovery is possible for the patient. However, even if the cancer cannot be cured, HIPEC can significantly increase life expectancy. Approximately two thirds of patients live 5 years or longer after having HIPEC surgery. The procedure also significantly decreases the severity of the symptoms of the disease.

How is the Procedure Performed?

 

HIPEC is conducted immediately after cytoreduction, that is, after the resection of organs and the destruction of all visible tumour foci.

The doctors place a drainage tube to provide outflow and inflow. Thermal sensors are used to monitor the intra-abdominal temperature. They are located in different parts of the peritoneal cavity. The abdominal skin is sutured with a temporary suture.

The next step is abdominal irrigation with a chemotherapy solution, heated to 42.5 celsius. The total perfusion is about 5 liters. The average flow rate is 700ml per minute. The perfusion is performed using a special apparatus. The average duration of the procedure is an hour and a half. Then, the doctors make a revision of the abdominal cavity. This drains and the surgical wound is sutured.

When treating peritoneal cancer, HIPEC has significant advantages over systemic chemotherapy, where drugs are taken orally or administered intravenously. The advantages are as follows:

  • pharmacokinetics – intracavitary administration of drugs can significantly increase the dose;
  • hyperthermia – heating of the drug makes it possible to increase the selective antitumor effect, increase the ablastic effect and increase the depth of penetration of the drug into the tumour tissues.

Where Can I Get treatment?

 

To treat cancer, patients often go to Germany.  This country achieves phenomenal successes in the fight against malignant tumours.  It successfully performs cytoreductive surgical procedures and uses intraperitoneal chemotherapy. Here is a list of the best clinics abroad, where patients can undergo treatment:

  • Helios Clinic Krefeld. Here, The Department of Abdominal and Minimally Invasive Surgery is responsible for performing cytoreductive surgery with intraperitoneal chemotherapy. The department shows excellent results in the treatment of abdominal cancers. The cost of treatment is about 40 thousand euros.
  • Charite University Hospital. This is one of the most reputable medical institutions in Europe. The surgery combined with hyperthermic chemotherapy is performed in the Department of General, Abdominal and Vascular Surgery. Cytoreductive surgery for oncological diseases remains one of the main department’s work focuses. The cost of treatment here reaches 60 thousand euros.
  • University Hospital of Ludwig Maximilian University. This hospital is included in the ranking of the top medical facilities specializing in the treatment of abdominal cancers. The cytoreductive surgical procedures with hyperthermic chemotherapy are performed in the Department of General, Abdominal and Transplant Surgery. The treatment cost is 45 thousand euros.

Treatment Organization

 

If you have symptoms of cancer, you can become a patient at one of Germany’s clinics. Booking Health will help you to organize your treatment in one of the best clinics abroad. Our services and benefits include:

  • Selecting the best clinic specializing in cytoreductive surgery with hyperthermic intraperitoneal chemotherapy.
  • A treatment cost reduction of up to 50% by eliminating coefficients for foreign patients.
  • The possibility of undergoing treatment at a date convenient for you.
  • An establishment of communication with doctors and the administration team before the start of treatment and after the end of the program.
  • The preparation of a treatment program without repeating previously completed examinations.
  • Monitoring of the program at all its stages.
  • Funds management and the return of any unspent funds.
  • The organization of additional examinations.
  • Assistance when purchasing and the transmission of medicines.

Booking Health will provide you with a high level of service. We will booka hotel and airline tickets for you, help you to complete the necessary paperwork, meet you at the airport and take you to the clinic by car.

Authors: Dr. Nadezhda Ivanisova, Dr. Sergey Pashchenko

To check for the Hyperthermic Intraperitoneal Chemotherapy (HIPEC) you can submit a request on BookingHealth and our managers will find the best hospital that is specialized in Hyperthermic Intraperitoneal Chemotherapy (HIPEC) to fulfill your needs
Cost of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) treatment varies from 25208.25 to 94544.25



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