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Hyperthermic Intraperitoneal Chemotherapy in Germany | Best Hospitals, Doctors, Prices | Bookinghealth

Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Germany

HIPEC procedure in Germany | Information about hospital in Germany and doctors | Rankings | Clinics | Prices | Send request to the hospital

Best hospitals and doctors for HIPEC surgery in Germany

Leading hospitals

Cost for treatment

Multimodality treatment of appendix cancer with cytoreductive surgery and HIPEC
51827
Multimodality treatment of colon cancer with cytoreductive surgery and HIPEC
51859
Multimodality treatment of duodenal cancer with cytoreductive surgery and HIPEC
51956
Multimodality treatment of gastrointestinal carcinoid tumors with cytoreductive surgery and HIPEC
51948
Multimodality treatment of mesothelioma with cytoreductive surgery and HIPEC
51792
Multimodality treatment of ovarian cancer with cytoreductive surgery and HIPEC
51818
Multimodality treatment of peritoneal carcinomatosis with cytoreductive surgery and HIPEC
44876.6
Multimodality treatment of pseudomyxoma peritonei with cytoreductive surgery and HIPEC
51935
Multimodality treatment of rectal cancer with cytoreductive surgery and HIPEC
52123
Multimodality treatment of stomach cancer with cytoreductive surgery and HIPEC
51875
General therapeutic rehabilitation
0.00
HELIOS Clinic Krefeld
Germany, Krefeld
HELIOS Clinic Krefeld
Overall rating9.7 / 10
Founded in 2014, the HELIOS Clinic Krefeld is one of the most modern medical facilities in Germany today. A team of highly qualified specialists, innovative medical equipment and comfortable accommodation conditions – the clinic has everything to make the treatment run smoothly and efficiently. Having crossed the threshold
Asklepios Hospital Barmbek Hamburg
Germany, Hamburg
Asklepios Hospital Barmbek Hamburg
Overall rating9.5 / 10
The Asklepios Hospital Barmbek Hamburg is an academic hospital of the University of Hamburg. The hospital was opened in 2005, and today it is one of the best and most modern medical centers in Europe. The priority areas of specialization of the medical facility are emergency medical care and comprehensive treatment of cancer, ur
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According to the Focus magazine, the University Hospital of Ludwig Maximilian University of Munich is regularly ranked among the best medical institutions in Germany! The hospital is the largest multidisciplinary medical facility, as well as a leading research and training center in Germany and Europe. The hospital is proud of i
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University Hospital Ulm
Germany, Ulm
University Hospital Ulm
Overall rating8.7 / 10
The University Hospital Ulm is an advanced medical complex that provides patients with high-class medical care using the very latest scientific achievements. The medical facility has been performing successful clinical activities for more than 40 years and has long earned an excellent reputation throughout Europe. The hospital r
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University Hospital Carl Gustav Carus Dresden
Germany, Dresden
University Hospital Carl Gustav Carus Dresden
Overall rating9.1 / 10
According to the reputable Focus magazine, the University Hospital Carl Gustav Carus Dresden ranks among the top five German hospitals! The hospital is the benchmark for modern high-quality medicine. Positioning itself as a maximum care medical facility, the hospital represents all medical fields. There are 26 specialized depart
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University Hospital Frankfurt am Main
Germany, Frankfurt am Main
University Hospital Frankfurt am Main
Overall rating10 / 10
According to the reputable Focus magazine, the University Hospital Frankfurt am Main ranks among the top German medical facilities! The hospital was founded in 1914 and today is a well-known German medical facility, which combines rich traditions and scientific innovations. A medical team of more than 6,500 employees cares about
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University Hospital RWTH Aachen
Germany, Aachen
University Hospital RWTH Aachen
Overall rating9.2 / 10
According to the prestigious Focus magazine, the University Hospital RWTH Aachen ranks among the top German hospitals! As a maximum care university medical facility, the hospital guarantees patients first-class medical services combined with a respectful and human attitude. The hospital integrates all the modern options for the
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University Hospital Marburg UKGM
Germany, Marburg
University Hospital Marburg UKGM
Overall rating8.6 / 10
The University Hospital Marburg UKGM offers patients modern diagnostics and comprehensive therapy at the international level. As a maximum care hospital, the medical facility specializes in all fields of modern medicine ranging from ophthalmology to traumatology and dentistry. The main areas of specialization of the hospital are
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University Hospital Halle (Saale)
Germany, Halle
University Hospital Halle (Saale)
Overall rating9.6 / 10
According to the prestigious Focus magazine, the University Hospital Halle (Saale) is one of the best medical institutions in Germany! The history of the hospital goes back more than 300 years, and during this time it has managed to gain an excellent reputation not only in Germany, but also throughout the world. The hospital pos
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University Hospital Jena
Germany, Jena
University Hospital Jena
Overall rating8.9 / 10
According to the prestigious Focus magazine, the University Hospital Jena regularly ranks among the top German medical facilities! The hospital has positioned itself as a multidisciplinary medical facility with a long history of more than 200 years. Since its foundation, the hospital has been constantly developing and modernizin
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University Hospital Heidelberg
Germany, Heidelberg
University Hospital Heidelberg
Overall rating9.8 / 10
According to Focus magazine, the University Hospital Heidelberg ranks among the top five hospitals in Germany! The hospital is one of the most advanced and reputable medical institutions not only in Germany, but throughout Europe. There are more than 43 specialized departments and 13 medical institutes, which cover all fields of
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University Hospital Hamburg-Eppendorf
Germany, Hamburg
University Hospital Hamburg-Eppendorf
Overall rating9.2 / 10
According to the Focus magazine, the University Hospital Hamburg-Eppendorf is one of the top ten hospitals in Germany! Since its foundation in 1889, the hospital has taken a leading position in the European medical arena, which it still holds today. A highly competent medical team of more than 15,300 employees takes care of the
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University Hospital Würzburg
Germany, Würzburg
University Hospital Würzburg
Overall rating9.2 / 10
According to the Focus magazine in 2019, the University Hospital Würzburg ranks among the top national German hospitals! The hospital is one of the oldest medical facilities in Germany. The centuries-old traditions of first-class treatment are combined with the very latest achievements of modern evidence-based medicine and
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University Hospital Tuebingen
Germany, Tuebingen
University Hospital Tuebingen
Overall rating9.2 / 10
According to the prestigious medical publication Focus, the University Hospital Tuebingen ranks among the top five German hospitals! The hospital was founded in 1805, therefore it is proud of its long history, unique experience, and outstanding achievements in the field of medical care, as well as research and teaching activitie
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| from Booking Health GmbH

Peritoneal cancer does not denote any specific malignant tumor. The disease often involves primary malignant neoplasms or metastases in the peritoneum from cancer of organs located in the abdominal cavity.

Content

  1. Overview
  2. Symptoms
  3. High-quality treatment in Germany
  4. Where can I undergo HIPEC surgery treatment in Germany?
  5. The cost of treatment in Germany
  6. How can I undergo HIPEC surgery treatment in Germany?

Overview

 

Peritoneal cancer is one of the most advanced types of progression of some oncological diseases. Peritoneal cancer is a medical form of the metastatic process in which tumor cells spread along the inner lining of the abdominal cavity. Its occurrence in most medical cases implies stage IV of the disease and is associated with a poor prognosis for patients. Peritoneal cancer is a secondary tumor lesion resulting from the progression of cancer of various localization. In some medical cases, the primary focus remains unidentified.

Treatment of peritoneal cancer is one of the most challenging tasks in oncology. Most often, the disease develops from the malignant neoplasms of the gastrointestinal tract, respiratory system, and female reproductive organs, such as stomach cancer, lung cancer, colon and small intestine cancer, ovarian cancer, tumors of the appendix, and pancreatic cancer.

Peritoneal cancer is an advanced medical stage of various tumors that have developed in intra-abdominal organs, such as the intestines, ovaries, appendix, stomach, pancreas, and liver. Tumors that develop directly from the tissue of the abdominal cavity (mesothelioma, pseudomyxoma) are rarely found in medical practice.

Peritoneal mesothelioma is a rare tumor. The incidence of the disease is constantly increasing and is closely related to exposure to asbestos. The tumor can affect all organs of the abdominal cavity and small pelvis and most likely affects the rectum, stomach, and ovaries.

Peritoneal pseudomyxoma is a primary tumor that usually originates in the appendix and has an average survival rate of 6 to 10 years in the case of classical medical treatment. Its main feature is that it fills the abdominal cavity with an unlimited amount of fluid, causing peritoneal effusion. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) are medical procedures that can provide quality treatment and often – a full quality recovery.

Symptoms

 

Since peritoneal cancer is not an independent disease, its medical picture is determined by the primary tumor's clinical manifestations and the actual signs of malignant lesions of the peritoneum. The most common symptoms that patients with peritoneal cancer experience are the accumulation of free fluid in the abdominal cavity, the so-called ascites. Ascites is often the only symptom in these patients. Besides, patients may experience nonspecific signs, such as significant weight loss, nausea, vomiting, severe fatigue, and weakness.

Treatment of the disease includes surgery on the primary tumor and regional metastases. Cytoreductive surgery includes peritonectomy and can be combined with the medical removal of the uterus and appendages, sigmoid colon, and gallbladder. After the surgery, the completeness of the cytoreduction score is assessed. However, even when determining the score, the possibility of dissemination cannot be completely excluded; therefore, hyperthermic intraperitoneal chemotherapy (HIPEC) is required.

High-quality treatment in Germany

 

Quality treatment approaches typically involve combination therapy, such as surgery and hyperthermic intraperitoneal chemotherapy (HIPEC).

During the surgery, the cancer-affected parts of the peritoneum are removed first. It is often necessary to remove parts of the organs near the affected peritoneum (for example, parts of the colon, stomach, or spleen). At the end of the surgery, drainage tubes are placed into the abdominal cavity. Hyperthermic intraperitoneal chemotherapy (HIPEC) is performed using a special pump through these tubes. The temperature of the solution used is about 42°C. Depending on the type of cancer, rinsing with various chemotherapy drugs is performed for 30-60 minutes, which ensures optimal contact of the chemical with all organs of the abdominal cavity while maintaining a high temperature and protecting medical personnel from contact with chemicals. After the surgery, the patient is transferred to the intensive care unit for 24 hours. The duration of stay in a hospital is about 2-3 weeks.

Drugs used for hyperthermic intraperitoneal chemotherapy (HIPEC) must have certain properties, including fast and deep penetration into the peritoneal tissues, synergy with hyperthermia, minimal systemic toxicity, and other physical factors.

Hyperthermic intraperitoneal chemotherapy (HIPEC) is one of the most effective treatment methods for many cancers. The idea behind hyperthermic intraperitoneal chemotherapy (HIPEC) is to deliver the drug directly to tumor cells on the inner lining of the abdominal cavity. Due to the extremely low effect of drugs on this area when administered intravenously or taken in the form of tablets, the delivery of heated drugs results in higher concentrations of chemotherapeutic substances in the tumor.

Another very effective combined method is using hyperthermic intraperitoneal chemotherapy simultaneously with intravenous administration of drugs for their more effective penetration into the intermediate layer of the peritoneum. These drugs also increase their activity in hyperthermia, and hyperthermic intraperitoneal chemotherapy makes the peritoneum a "temperature target".

A patient must meet certain criteria to be a candidate for hyperthermic intraperitoneal chemotherapy (HIPEC) treatment. These include:

  • Metastatic cancer should be confined to the abdomen and not spread to distant organs, which should be confirmed by a CT scan of the chest and abdomen or PET-CT.
  • The patient must be in good medical condition and not have any other comorbidities such as severe kidney disease or cardiovascular disease.

Depending on the results of the pathological examination and efficacy of surgery, additional systemic chemotherapy may be required in some cases. Therefore, each case is discussed with the participation of specialists from the fields of oncology and radiation therapy.

In general, this type of therapy still cannot be called completely harmless, even considering fewer medical side effects than conventional chemotherapy. Therefore, a preliminary medical examination and a detailed discussion of the problem the patient experiences are mandatory.

In addition to the potential benefits that hyperthermic intraperitoneal chemotherapy (HIPEC) provides regarding improving quality of life and increasing life expectancy, it is important to remember that due to the complexity of such surgery, patients may experience certain complications. To significantly reduce these risks, the preoperative assessment procedures are performed by highly trained and competent personnel in hospitals in Germany who specialize in those unique medical procedures.

At its core, hyperthermic intraperitoneal chemotherapy (HIPEC) is a treatment method aimed at recovery. Treatment is most successful when the tumor has spread only to the peritoneum and there are no metastases carried by the blood or lymph flow. However, data has been accumulated on the successful treatment with hyperthermic intraperitoneal chemotherapy (HIPEC) in the presence of metastases in the liver or the involvement of lymph nodes.

Published studies show that hyperthermic intraperitoneal chemotherapy (HIPEC) results are superior to those of conventional chemotherapy or surgery. Now, there is an increase in life expectancy and quality of life in patients who were previously considered incurable. For example, the implementation of hyperthermic intraperitoneal chemotherapy (HIPEC) in hospitals in Germany has treated ovarian cancer in the most advanced and complex forms of it. The main advantage of the hyperthermic intraperitoneal chemotherapy (HIPEC) method is that it allows a higher dose of chemotherapy drugs, increasing the chances of killing cancer. The HIPEC dose is 20 times bigger than the dose of conventional chemotherapy for stage IV cancer.

 

Where can I undergo HIPEC surgery treatment in Germany?

 

Medical tourism is becoming more and more popular these days, as medicine in Germany ensures a much better quality of peritoneal cancer treatment with surgery and hyperthermic intraperitoneal chemotherapy (HIPEC).

The following hospitals show the best success rates in peritoneal cancer treatment with surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) in Germany:

  1. HELIOS Clinic Krefeld
  2. Academic Hospital Asklepios Barmbek Hamburg
  3. University Hospital of Ludwig Maximilian University of Munich
  4. Charite Hospital Berlin
  5. University Hospital Ulm

You can find more information about the hospitals in Germany on the Booking Health website.

The cost of treatment in Germany

 

The prices in hospitals listed on the Booking Health website are relatively low. With Booking Health, you can undergo quality cancer treatment with HIPEC surgery in Germany at an affordable price.

The cost of treatment varies, as the prices depend on the hospitals, specifics of the disease, and the complexity of its treatment.

The cost of peritoneal cancer treatment with surgery and hyperthermic intraperitoneal chemotherapy HIPEC in Germany is 38,402-67,578 EUR.

You also need to consider the cost of additional medical procedures and follow-up care services. Therefore, the ultimate cost of treatment in Germany may differ from the initial price.

To make sure that the overall cost of treatment in Germany is suitable for you, contact us by leaving the request on the Booking Health website.

How can I undergo HIPEC surgery treatment in Germany?

 

It is not easy to self-organize any treatment abroad. It requires certain knowledge and experience. Thus, it is safer, easier, and less stressful to use the services of a medical tourism agency.

As the largest and most transparent medical tourism agency globally, Booking Health has up-to-date information about peritoneal cancer treatment with surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) in the best hospitals in Germany. Therefore, we will help you select the right clinic in Germany, considering your wishes for treatment.

We want to help you and take on all the troubles. You can be free of unnecessary stress while Booking Health takes care of all organizational issues regarding the treatment in hospitals in Germany. Our services are aimed at undergoing quality peritoneal cancer treatment in Germany with surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) safely and successfully.

The arrangement of quality treatment can be easy! To know more about the services we provide, leave a request on the Booking Health website, and our manager will contact you shortly.

 

Authors: 

The article was edited by medical experts, board-certified doctors Dr. Nadezhda Ivanisova and Dr. Sergey Pashchenko. For the treatment of the conditions referred to in the article, you must consult a doctor; the information in the article is not intended for self-medication!

 

Sources:

National Center for Biotechnology

Cancer Research Institute

American Cancer Society