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Chemoembolization

Due to the difficulties associated with the organization of treatment in Turkey, Switzerland and South Korea, we have currently suspended the processing of requests to these regions.

If you are interested in treatment in Germany, please leave a request and our specialists will contact you as soon as possible.

 

Cost for treatment

Treatment of liver cancer with percutaneous embolization (coiling) or chemoembolization
 from  4640
Treatment of adrenal cancer with embolization or chemoembolization
 from  23810
Treatment of bladder cancer with embolization or chemoembolization
 from  23611

University Hospital Rechts der Isar Munich

9.8/10
location_onGermany, Munich

Department of Diagnostic and Interventional Radiology

According to the prestigious FOCUS magazine, the University Hospital Rechts der Isar Munich ranks among the Germany's top medical institutions! Founded in 1834, the hospital combines long traditions and the very latest achievements of modern medicine. The medical facility includes 33 specialized departments, 20 interdiscipli
Treatment of liver cancer with percutaneous embolization (coiling) or chemoembolization
9938
Treatment of bladder cancer with embolization or chemoembolization
30467
Treatment of bladder cancer with embolization or chemoembolization
29963

Hospital Kassel

9.9/10
location_onGermany, Kassel

Department of Diagnostic and Interventional Radiology, Nuclear Medicine

The Hospital Kassel is a progressive medical facility with a huge medical team, which provides high-quality medical services in all branches of modern medicine. The hospital is part of the regional medical Gesundheit Nordhessen Holding, which unites 5 top-class medical centers, including specialized rehabilitation clinics. With
Treatment of liver cancer with percutaneous embolization (coiling) or chemoembolization
8834
Treatment of liver metastases with percutaneous embolization (coiling) or chemoembolization
8767

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Department of Adult and Pediatric Diagnostic, Interventional Radiology

According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! The hospital is one of the largest and leading university medical complexes in Europe. The hospital in Germany provides modern diagnostics and treatment of patients, a
Treatment of liver cancer with percutaneous embolization (coiling) or chemoembolization
12700
Treatment of adrenal cancer with embolization or chemoembolization
40083
Treatment of bladder cancer with embolization or chemoembolization
40002

MediClin Robert Janker Clinic

9.5/10
location_onGermany, Bonn

Department of Diagnostic and Interventional Radiology

The MediClin Robert Janker Clinic is a progressive medical facility, which has all the very latest diagnostic and treatment methods for the recovery of health of patients who suffer from cancers. The clinic was founded by renowned radiologist and surgeon Robert Janker. Today, its history has more than 80 years of successful clin
Treatment of liver cancer with percutaneous embolization (coiling) or chemoembolization
9531
Treatment of bladder cancer with embolization or chemoembolization
28837
Treatment of liver metastases with percutaneous embolization (coiling) or chemoembolization
9528

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of Adult and Pediatric Diagnostic, Interventional Radiology, Neuroradiology

According to the prestigious Focus magazine, the University Hospital Halle (Saale) ranks among the top German medical facilities! The history of the hospital has more than 300 years, and during this time it managed to earn an excellent reputation not only in Germany, but throughout the world. The hospital positions itself as a s
Treatment of liver cancer with percutaneous embolization (coiling) or chemoembolization
8804
Treatment of adrenal cancer with embolization or chemoembolization
26766
Treatment of bladder cancer with embolization or chemoembolization
26975

University Hospital Muenster

9.8/10
location_onGermany, Muenster

Department of Adult and Pediatric Diagnostic, Interventional Radiology, Neuroradiology

According to the Focus magazine, the University Hospital Muenster ranks among the top German hospitals! The hospital belongs to the most prestigious medical institutions in Germany. The hospital is distinguished by a high professionalism of its doctors, state-of-the-art technological equipment and the availability of the most ad
Treatment of liver cancer with percutaneous embolization (coiling) or chemoembolization
8911
Treatment of adrenal cancer with embolization or chemoembolization
26714
Treatment of bladder cancer with embolization or chemoembolization
26960

HELIOS University Hospital Wuppertal

9.8/10
location_onGermany, Wuppertal

Department of Neuroradiology

The HELIOS University Hospital Wuppertal is a well-known maximum care hospital and an advanced rehabilitation center in Germany. The hospital belongs to the Witten-Herdecke University and, with its 1000 beds, is the largest one in the Bergisches Land region. Within the 26 departments of the hospital, the whole spectrum of medica
Treatment of liver cancer with percutaneous embolization (coiling) or chemoembolization
8733
Treatment of adrenal cancer with embolization or chemoembolization
26797
Treatment of bladder cancer with embolization or chemoembolization
27200

University Hospital Oldenburg

10/10
location_onGermany, Oldenburg

Department of Adult and Pediatric Diagnostic, Interventional Radiology

According to the Focus magazine, the University Hospital Oldenburg ranks among the best medical facilities in Germany! The hospital offers a wide range of medical services that meet the highest medical standards. The hospital has 832 beds. The medical facility annually serves 37,000 patients on an inpatient and partially inpatie
Treatment of liver cancer with percutaneous embolization (coiling) or chemoembolization
7937
Treatment of adrenal cancer with embolization or chemoembolization
23810
Treatment of bladder cancer with embolization or chemoembolization
23892

University Hospital Saarland Homburg

9.8/10
location_onGermany, Homburg

Department of Diagnostic and Interventional Neuroradiology

The University Hospital Saarland is the largest hospital in the city of Homburg and the most important medical facility in the region. The hospital, which currently has 30 specialized departments and 20 institutes, was founded in 1947 and operates on the basis of the Saarland University. The hospital plays a leading role in medi
Treatment of liver cancer with percutaneous embolization (coiling) or chemoembolization
8558
Treatment of bladder cancer with embolization or chemoembolization
25114
Treatment of bladder cancer with embolization or chemoembolization
25367

Vivantes Neukölln Hospital Berlin

10/10
location_onGermany, Berlin

Department of Clinical and Interventional Neuroradiology

The Vivantes Neukölln Hospital is the maximum care hospital and one of the largest healthcare facilities in Berlin.  There are more than 20 specialized departments and centers, including pediatric departments. In total, the hospital has 1,200 beds. The hospital uses innovative technologies and the latest treatments, as
Treatment of liver cancer with percutaneous embolization (coiling) or chemoembolization
9184
Treatment of liver cancer with percutaneous embolization (coiling) or chemoembolization
9489
Treatment of liver metastases with percutaneous embolization (coiling) or chemoembolization
9347

Bundeswehr Academic Hospital Berlin

10/10
location_onGermany, Berlin

Department of Diagnostic and Interventional Radiology

The Bundeswehr Academic Hospital Berlin is a modern medical facility that offers first-class medical care in the field of emergency care, traumatology, urology, internal medicine, surgery, neurosurgery, neurology, nuclear medicine and other focuses. The hospital has 15 specialized departments, medical teams of which guarantee th
Treatment of liver cancer with percutaneous embolization (coiling) or chemoembolization
8417
Treatment of liver metastases with percutaneous embolization (coiling) or chemoembolization
8331

University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of Adult and Pediatric Diagnostic, Interventional Radiology, Neuroradiology

The University Hospital Ulm started its activities 35 years ago and during this time it has become one of the most prestigious medical institutions in Europe. The hospital is famous for its numerous discoveries and the world-class achievements in medicine and pharmaceuticals. The medical facility has 29 specialized departments a
Treatment of liver cancer with percutaneous embolization (coiling) or chemoembolization
9460
Treatment of bladder cancer with embolization or chemoembolization
28324
Treatment of bladder cancer with embolization or chemoembolization
28804

HELIOS Clinic Krefeld

9.7/10
location_onGermany, Krefeld

Department Adult and Pediatric Diagnostic, Interventional Radiology, Neuroradiology

Founded in 2014, the HELIOS Clinic Krefeld is one of the most modern medical facilities in Germany today. A team of highly qualified specialists, innovative medical equipment and comfortable accommodation conditions – the clinic has everything to make the treatment run smoothly and efficiently. Having crossed the threshold
Treatment of liver cancer with percutaneous embolization (coiling) or chemoembolization
8260
Treatment of liver metastases with percutaneous embolization (coiling) or chemoembolization
8248

DKD HELIOS Clinic Wiesbaden

9.13636/10
location_onGermany, Wiesbaden

Department of Diagnostic Radiology

The DKD HELIOS Clinic Wiesbaden has long made a name for itself in the international medical arena by introducing an optimal model of medical care, combining the use of the most advanced medical technologies, the experience of highly qualified doctors and impeccable quality of patient care. The medical facility first opened its
Treatment of liver cancer with percutaneous embolization (coiling) or chemoembolization
8529
Treatment of liver metastases with percutaneous embolization (coiling) or chemoembolization
8585

Hospital Neuperlach Munich

9.8/10
location_onGermany, Munich

Department of Diagnostic and Interventional Radiology

The Hospital Neuperlach Munich provides modern medical services of the highest quality. The medical center is an Academic Hospital of the Ludwig Maximilian University of Munich, and therefore it can offer its patients innovative diagnostic and therapeutic methods available only in the best German hospitals. The medical complex o
Treatment of liver cancer with percutaneous embolization (coiling) or chemoembolization
8274
Treatment of bladder cancer with embolization or chemoembolization
25304
Treatment of liver metastases with percutaneous embolization (coiling) or chemoembolization
8473

Hospital Schwabing Munich

8.5/10
location_onGermany, Munich

Department of Adult and Pediatric Diagnostic, Interventional Radiology

The Hospital Schwabing Munich is one of the oldest medical facilities in the Schwabing region with a history of over 100 years. The hospital is proud of the excellent state-of-the-art equipment, modern infrastructure, highly professional medical personnel and location in a picturesque park area. The medical complex is the academ
Treatment of liver cancer with percutaneous embolization (coiling) or chemoembolization
8608
Treatment of bladder cancer with embolization or chemoembolization
25105
Treatment of liver metastases with percutaneous embolization (coiling) or chemoembolization
8541
| from Booking Health GmbH

Content

  1. Chemoembolization in hepatocellular carcinomas
  2. Chemoembolization in other types of cancer
  3. How the chemoembolization is carried out
  4. Results and benefits of the chemoembolization
  5. Where to undergo chemoembolization

 

The transarterial chemoembolization (TACE) is the therapeutic measure that combines two mechanisms of action – local introduction of the chemotherapeutic agent and blockage of the artery that feeds the tumor with emboli. The procedure is effective in tumors with active vascularization, i.e. in the primary and metastatic liver cancer, breast cancer, lung cancer and other types of oncology. Despite being minimally invasive, chemoembolization is carried out in the Departments of Interventional Radiology, by healthcare professionals with qualifications in this sphere. Cost of treatment in leading hospitals corresponds with its clinical efficacy.

Chemoembolization in hepatocellular carcinomas

 

First, chemoembolization was implemented into the clinical practice for the treatment of intermediate or advanced stage hepatocellular carcinoma. Before implementation of this method, only palliative treatment options were available for the patients with such stages of liver cancer. Patients were treated with symptomatic medicines and their life expectancy was under 20 months. With transarterial chemoembolization, life expectancy extends significantly.

Patients with both primary hepatocellular carcinoma and metastatic liver lesions are eligible for the procedure. Metastases from colorectal tumors, sarcomas, and even ocular melanoma can be detected here as the systemic circulation carries all the blood through the liver for the detoxification.

However, in particular liver conditions patients are treated with chemoembolization with certain precautions. These are liver cirrhosis, blockage of the portal vein or bile ducts, extensive tumor spreading throughout the organ, and numerous extra-hepatic metastases. Thus, before admitting to the hospital’s Department of Interventional Radiology for performing the procedure a patient undergoes obligatory examination. After assessing the information about the patient's health, a doctor prescribes the procedure or recommends to choose another therapeutic option.

Chemoembolization in other types of cancer

 

Another sphere of medicine where TACE is used is breast cancer treatment. In this case TACE mostly serves as the regional chemotherapy, as the systemic chemotherapy for breast cancer is often associated with severe side effects. Before performing chemoembolization, a doctor collects the information about the number and location of arteries that feed the tumor, as the individual and age-related variability of the breast arteries is often present.

The selective chemoembolization of lung cancer is the suitable treatment for lung metastases, and for the primary lung tumor (non‐small cell lung cancer). TACE demonstrates efficacy in the presence of mediastinal, pleural, endobronchial and lung metastatic foci. In addition, it treats tumors that respond poorly or are not responding at all to systemic chemotherapy, as well as cannot be destroyed by means of resection, ablation or even stereotactic body radiation therapy. In particular patients, TACE (which is called TPCE, transpulmonary chemoembolization, in this case) is used for making the primary tumor more resectable. In other patients it may be used as the palliative therapeutic option.

Due to the peculiarities of blood supply, TACE is also carried out in women with cervical cancer. The procedure is efficient in locally advanced tumors that have not spread the metastases to lymph nodes or distant organs. Uterine artery chemoembolization (UACE) reduces the tumor volume and facilitates the subsequent surgery. For achieving better effect, in certain hospitals it can be followed by preoperative radiation therapy.

The information about the role of TACE in the treatment of other cancers is limited. Nevertheless, particular clinical trials and case reports specify its administration in patients with pancreatic cancer, sarcomas of bones and soft tissues, and neuroendocrine tumors (NETs).

In chemoembolization, blood flow in the vessels of the tumor is blocked, and a high dosage of the chemotherapeutic drug is injected locally.

The procedure is used in the treatment of malignant diseases – liver cancer, breast cancer, lung cancer, etc.

The best hospitals in Europe are University Hospital Halle, University Hospital Muenster, and HELIOS University Hospital Wuppertal (Germany).

Prices are as follows:

DiseaseCost
Liver cancerfrom 4,700 €
Liver metastasesfrom 4,750 €

How the chemoembolization is carried out

 

The procedure starts from introducing a small flexible catheter into the femoral artery. Being moved slowly along the blood vessel under visual guidance (fluoroscopic or tomographic one), a catheter reaches the target area (uterine artery, pulmonary artery, liver artery, etc.). 

After that, high dosage of the chemotherapeutic agent is injected through the catheter. The chemotherapeutic drug is selected individually, considering tumor type and its susceptibility. For instance, doxorubicin or cisplatin are mainly used in patients with liver malignancies, women with cervical cancer are treated with carboplatin, etc. After the drug introduction, the artery is blocked with an embolus, so that the drug stays inside the tumor and does not enter the systemic blood circulation.

In the interventional radiology hospitals, two types of emboli are used:

  1. Mixture of a chemotherapeutic drug and lipiodol. Lipiodol is a hydrophobic substance that forms blocking spheres inside the blood vessels.
  2. Embolic drug-eluting beads. These are microspheres with better pharmacokinetic profile. In using these occluding agents, the chemotherapeutic drug is released slowly, which contributes to long-lasting antitumor effect.

Results and benefits of the chemoembolization

 

Due to the double mechanism of action, high selectivity, and minimal invasiveness, chemoembolization is characterized by:

  1. Good tolerance, there is no need for long-term recovery (as the procedure does not require thoracotomy or other invasive interventions).
  2. Administration of higher doses of chemotherapeutic drugs as compared to the conventional systemic chemotherapy.
  3. Absence of typical for the systemic chemotherapy side effects.
  4. High efficacy, even in tumors that are resistant to the systemic chemotherapy, do not respond to stereotactic body radiation therapy and are inoperable.
  5. Efficacy in tumors of any size, including unresectable neoplasms; possibility of tumor shrinkage and its subsequent surgical removing.
  6. Possibility of combining with other therapeutic options, such as tumor ablation or radiation therapy.

In most cases, TACE itself is not the curative procedure, but it is included in modern treatment protocols of leading hospitals as it is able to extend life expectancy and provide patients with symptoms improvement.

Where to undergo chemoembolization

 

Regardless of the tumor type, chemoembolization is performed in the Departments of Interventional Radiology, after the obligatory preliminary examination and consultations with healthcare professionals. Many cancer patients do not have this innovative and high-technology treatment option in their native countries. Such patients may receive medical services in hospitals abroad with the help of Booking Health.

On the Booking Health website patients can find reliable and detailed information about hospitals and doctors that specialize in TACE, cost of treatment and prices for related services, available appointments, etc. As prices in the different hospitals may differ significantly, a patient may compare the cost of treatment in few suitable healthcare facilities and choose the most favourable price.

Booking Health specialists guide the patient during all stages of trip and undergoing medical program:

  • Choosing the hospital based on its specialization and success rates
  • Establishing communication with your doctor, elaborating the preliminary medical program for undergoing TACE
  • Providing favorable cost of treatment, without additional coefficients for foreign patients (saving up to 50%)
  • Booking the appointment on the necessary date
  • Monitoring of the medical program by independent Booking Health specialists
  • Communication with the hospital after TACE completion
  • Control of invoices and return of unspent funds
  • Organization of additional examinations after TACE completion
  • Booking accommodation and airline tickets, transfer organization
  • Services of interpreter

To start planning your treatment, please, leave the request on the Booking Health website. A patient case manager or medical advisor will contact you the same day to discuss the TACE procedure.

Authors: Dr. Nadezhda IvanisovaDr. Farrukh Ahmed




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