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Female Infertility: Treatment of the Disease

Due to the difficulties associated with the organization of treatment in Turkey, Switzerland, South Korea and India, we are not currently processing requests to these regions.

If you are interested in treatment in Germany, please leave a request and our specialists will contact you as soon as possible.

 

Cost for treatment

Testing and Diagnosis for Female Infertility
522
In vitro fertilization (IVF) long protocol
2629.84
In vitro fertilization (IVF) short protocol
2296.8

PAN Clinic Cologne

9.8/10
location_onGermany, Cologne

Department of Reproductive Medicine

The PAN Clinic Cologne is a multidisciplinary medical facility that combines advanced medicine, excellent quality of patient care and a high level of comfort. Founded in 1999, the clinic is located in the very heart of Cologne. During this time, the medical complex has gained long clinical experience, but at the same time it has
Testing and Diagnosis for Female Infertility
3225.96
In vitro fertilization (IVF) long protocol
20266.64
In vitro fertilization (IVF) short protocol
13870.05

University Hospital Tuebingen

9.2/10
location_onGermany, Tuebingen

Department of Adult and Pediatric Gynecology, Mammology, Obstetrics

According to the prestigious medical publication Focus, the University Hospital Tuebingen ranks among the top five German hospitals! The hospital was founded in 1805, therefore it is proud of its long history, unique experience, and outstanding achievements in the field of medical care, as well as research and teaching activitie
Testing and Diagnosis for Female Infertility
3265.63
Diagnostic laparoscopy of female infertility
7994.05
Laparoscopic dissection of adhesions in secondary female infertility
8299.94

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Department of Adult and Pediatric Gynecology, Mammology

According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! The hospital is one of the largest and leading university medical complexes in Europe. The hospital in Germany provides modern diagnostics and treatment of patients, a
Testing and Diagnosis for Female Infertility
4357.65
Diagnostic laparoscopy of female infertility
10893.24
Laparoscopic dissection of adhesions in secondary female infertility
11013.3

University Hospital Heidelberg

9.8/10
location_onGermany, Heidelberg

Department of Adult and Pediatric Gynecological Endocrinology, Reproductive Medicine

According to Focus magazine, the University Hospital Heidelberg ranks among the top five hospitals in Germany! The hospital is one of the most advanced and reputable medical institutions not only in Germany, but throughout Europe. There are more than 43 specialized departments and 13 medical institutes, which cover all fields of
Testing and Diagnosis for Female Infertility
0
In vitro fertilization (IVF) long protocol
0
In vitro fertilization (IVF) short protocol
0

University Hospital Rechts der Isar Munich

9.8/10
location_onGermany, Munich

Department of Gynecology, Mammology and Obstetrics

The University Hospital Rechts der Isar Munich was founded in 1834. It combines long traditions with the very latest advances in modern medicine. The medical facility includes 33 specialized departments and 20 interdisciplinary centers, where patients can receive top-class medical care in all medical fields. The hospital annuall
Testing and Diagnosis for Female Infertility
3299.04
Diagnostic laparoscopy of female infertility
7994.05
Laparoscopic dissection of adhesions in secondary female infertility
8310.38

University Hospital Duesseldorf

9.5/10
location_onGermany, Duesseldorf

Department of Adult and Pediatric Gynecology, Obstetrics and Mammology

According to the authoritative Focus magazine, the University Hospital Duesseldorf ranks among the top Germany hospitals! The hospital is an excellent example of a combination of high-quality health care, research and teaching activities. With more than 50,000 inpatients and about 300,000 outpatients every year, the hospital is
Testing and Diagnosis for Female Infertility
3406.57
Diagnostic laparoscopy of female infertility
8488.9
Laparoscopic dissection of adhesions in secondary female infertility
8829.25

University Hospital Muenster

9.8/10
location_onGermany, Muenster

Department of Adult and Pediatric Gynecology, Obstetrics

According to the Focus magazine, the University Hospital Muenster ranks among the top German hospitals! The hospital belongs to the most prestigious medical institutions in Germany. The hospital is distinguished by a high professionalism of its doctors, state-of-the-art technological equipment and the availability of the most ad
Testing and Diagnosis for Female Infertility
3246.84
In vitro fertilization (IVF) long protocol
19098.4
In vitro fertilization (IVF) short protocol
13147.6

University Hospital of Ludwig Maximilian University of Munich

10/10
location_onGermany, Munich

Department of Reproductive Medicine

According to the Focus magazine, the University Hospital of Ludwig Maximilian University of Munich is regularly ranked among the best medical institutions in Germany! The hospital is the largest multidisciplinary medical facility, as well as a leading research and training center in Germany and Europe. The hospital is proud of i
Testing and Diagnosis for Female Infertility
3445.2
In vitro fertilization (IVF) long protocol
21517.35
In vitro fertilization (IVF) short protocol
14362.82

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of Reproductive Medicine and Andrology

According to the prestigious Focus magazine, the University Hospital Halle (Saale) ranks among the top German medical facilities! The history of the hospital has more than 300 years, and during this time it managed to earn an excellent reputation not only in Germany, but throughout the world. The hospital positions itself as a s
Testing and Diagnosis for Female Infertility
3160.18
In vitro fertilization (IVF) long protocol
18843.66
In vitro fertilization (IVF) short protocol
13104.8

University Hospital RWTH Aachen

8.9/10
location_onGermany, Aachen

Department of Adult and Pediatric Gynecological Endocrinology, Reproductive Medicine

According to the prestigious Focus magazine, the University Hospital RWTH Aachen ranks among the top German hospitals! As a maximum care university medical facility, the hospital guarantees patients first-class medical services combined with a respectful and human attitude. The hospital integrates all the modern options for the
Testing and Diagnosis for Female Infertility
3435.8
In vitro fertilization (IVF) long protocol
21582.08
In vitro fertilization (IVF) short protocol
14191.6

Medipol Mega University Hospital Istanbul

8/10
location_onTurkey, Istanbul

Department of Reproductive Medicine

Testing and Diagnosis for Female Infertility
2855.34
In vitro fertilization (IVF) long protocol
23452.42
In vitro fertilization (IVF) short protocol
13830.91

Hospital Neuperlach Munich

9.8/10
location_onGermany, Munich

Department of Gynecology, Gynecologic Oncology, Urogynecology, Mammology and Obstetrics

The Hospital Neuperlach Munich provides modern medical services of the highest quality. The medical center is an Academic Hospital of the Ludwig Maximilian University of Munich, and therefore it can offer its patients innovative diagnostic and therapeutic methods available only in the best German hospitals. The medical complex o
Testing and Diagnosis for Female Infertility
2974.35
Diagnostic laparoscopy of female infertility
7390.62
Laparoscopic dissection of adhesions in secondary female infertility
7581.67

Memorial Bahcelievler Hospital Istanbul

9.2/10
location_onTurkey, Istanbul

Department of Reproductive Medicine

The Memorial Bahçelievler Hospital Istanbul is an advanced multidisciplinary medical center that began its clinical practice in 2018. It is part of the world famous Memorial Healthcare Group. The hospital was designed in accordance with the very latest standards of modern architecture with the aim of providing top-class m
Testing and Diagnosis for Female Infertility
2908.58
In vitro fertilization (IVF) long protocol
23674.79
In vitro fertilization (IVF) short protocol
13414.36

Memorial Atasehir Hospital Istanbul

9.3/10
location_onTurkey, Istanbul

Department of Reproductive Medicine

The Memorial Atasehir Hospital Istanbul is a private medical complex, within the walls of which the patient is expected to receive excellent medical care and responsive care. The medical complex is part of the Memorial Healthcare Group, which consists of 14 hospitals that provide a wide range of services. The hospital began its
Testing and Diagnosis for Female Infertility
2940.95
In vitro fertilization (IVF) long protocol
23651.82
In vitro fertilization (IVF) short protocol
13440.46

Memorial Sisli Hospital Istanbul

9.2/10
location_onTurkey, Istanbul

Department of Reproductive Medicine

The Memorial Sisli Hospital Istanbul is the largest and leading medical complex in Turkey, which meets the highest standards of medical care when providing the advanced diagnostics and treatment using the very latest methods. The hospital is part of the Memorial Health Group – it was the first project of this provider of m
Testing and Diagnosis for Female Infertility
2831.33
In vitro fertilization (IVF) long protocol
23368.9
In vitro fertilization (IVF) short protocol
13322.48

Rabin Medical Center Petah Tikva

8.9/10
location_onIsrael, Petah Tikva

Department of Reproductive Medicine

The Rabin Medical Center Petah Tikva has the status of one of the largest and reputable multidisciplinary Israeli hospitals. Since its establishment, the center has proven itself as the founder of new standards in medical care and has become a leader in the use of innovative medical technologies at the international level. It su
Testing and Diagnosis for Female Infertility
2834.46
In vitro fertilization (IVF) long protocol
23662.26
In vitro fertilization (IVF) short protocol
13331.88
| from Booking Health GmbH

Infertility is the absence of a pregnancy within 12 months of regular sexual life. This diagnosis is initially made for a married couple, since at the time of establishing the fact of the absence of a pregnancy, it is still unknown who has diseases of the reproductive system organs that prevent conception: a man, a woman, or both spouses. According to the diagnostic results, female infertility can be identified, which is more common than male infertility. This state, however, is not forever. Most women can get pregnant after receiving medical attention from doctors. If you have trouble getting pregnant, you can undergo your diagnostics and treatment abroad. You are welcome to visit the Booking Health website to find out the prices and compare the cost of treatment at different Centers for Reproductive Medicine. We will help you choose a hospital and arrange your treatment abroad.

Content

  1. Causes
  2. Diagnostics
  3. Conservative treatment
  4. Surgical treatment
  5. Assisted reproductive technologies
  6. Where to undergo your diagnostics and treatment?

Causes

 

To choose strategies for the treatment of female infertility, it is necessary to first determine the reasons for the disease in order to cure or control it. The most common causes are the following:

  • ovulation disorders due to a hormonal imbalance cause 25% of cases of female infertility; 
  • endometriosis causes infertility in 15% of cases;
  • pelvic adhesions cause infertility in 12% of cases;
  • fallopian tube obstruction causes infertility in 11% of cases;
  • diseases of the uterus cause infertility in 11% of cases;
  • hyperprolactinemia is the reason for infertility in 7% of cases.

According to the mechanism of development, the two leading reasons for infertility are hormonal imbalances that interfere with the maturation of the egg, as well as tubal and peritoneal factors (pelvic adhesions and fallopian tube obstruction), which prevent the transport of the egg. The uterine factor that implies a violation of the attachment of a fertilized egg in the uterus is much less common.

Diagnostics

 

Diagnostics of infertility is no less important than its treatment. If the cause of reproductive dysfunction is established, it can usually be eliminated or compensated for.

A diagnostic examination is required for both partners. In the structure of infertility among married couples, female infertility accounts for 37%, male infertility accounts for 8%, and in 35% of cases, diseases of the reproductive system organs may be detected in both spouses. In other cases, the reasons for infertility remain unclear because both spouses are clinically healthy but the woman still cannot get pregnant. With the development of medicine, the proportion of both female and male infertility of unknown origin continues to decline as more and more causes of infertility may be discovered during the diagnostics.

A man undergoes a spermogram and a MAR test. These tests can determine the quantity, concentration, mobility, and structure of spermatozoa and the degree of their damage by antibodies (to exclude immune infertility). If the results of these tests are normal, any additional examination is not required.

Women can undergo their diagnostics using the following methods:

  • a gynecological examination, vaginal flora smears, bacterial smears, and smears for oncocytology from the cervix of the uterus;
  • hormone blood tests;
  • a hysterosalpingography, which is a contrast-enhanced X-ray examination of the uterus and fallopian tubes to assess their patency;
  • an ultrasound scan of the pelvic organs.

The above-listed tests are usually enough to identify the reasons for infertility. Occasionally, they may remain unexplained. In this case, a woman will need additional examinations, such as genetic and immunologic tests, blood coagulation tests, and a hysteroscopy (an endoscopic examination of the uterus).

Conservative treatment

 

The most common type of infertility is due to endocrine disorders. Hormonal imbalances can be corrected with medicines, or ovulation can be achieved for several cycles in a row so that a woman can get pregnant.

Methods of treatment of infertility with hormone therapy depend on the identified cause:

  • patients with hypothyroidism (thyroid dysfunction) undergo thyroid hormone replacement therapy;
  • patients with hyperprolactinemia take dopamine receptor antagonists;
  • patients with luteal phase defects are treated with progesterone;
  • patients with excess adrenal function take low doses of glucocorticoids to suppress it. 

When endocrine disorders cannot be eliminated or compensated for, doctors switch to the use of ovulation induction medications. They prescribe women antiestrogens, which are taken as pills. If no ovulation occurs after three cycles, or if a pregnancy does not occur after six cycles, gonadotropins (FSH and LH preparations) may be used to stimulate the ovaries. 

Surgical treatment

 

Basically, surgical treatment can be performed for the following two types of infertility:

  • tubal and peritoneal factors (fallopian tube obstruction and pelvic adhesions);
  • uterine factor (anomalies in the development of the uterus, intrauterine synechiae, or uterine fibroids).

Doctors in developed countries perform surgery to restore the patency of the fallopian tubes with laparoscopic techniques. This is a minimally invasive operation, after which women recover in 2 weeks.

Operations on the uterus are performed mainly during a hysteroscopy. These are endoscopic interventions that are done from the inside of the uterus with thin, long instruments under the control of a tiny video camera.

Assisted reproductive technologies

 

Women whose infertility has not been corrected with surgery or conservative therapy are candidates for artificial insemination. If, based on the results of the diagnostics, doctors conclude that getting pregnant with other methods is unlikely, a patient can be immediately referred to IVF.

The essence of the treatment is drug stimulation of the ovaries. The ovaries are then punctured to obtain eggs. They are fertilized with the husband's sperm. Within a few days, the embryos are grown on a nutrient medium. One or more embryos are then transferred to the uterus, and the rest are frozen. If unsuccessful, they can be transferred in the next cycle, avoiding repeated ovarian stimulation.

Where to undergo your diagnostics and treatment?

 

If you cannot conceive a child after 12 months of trying, and over the age of 35, after 6 months of trying, you should seek medical attention from specialists in reproductive medicine. You can undergo your diagnostics and treatment abroad at one of the best hospitals in the world. In developed countries, you will receive top-class medical services. You can find out the cost of treatment and compare prices on the Booking Health website. We will take care of all the arrangements for your treatment abroad on your preferred dates.

There are a few reasons for you to use the services of foreign doctors: 

  • high-precision diagnostics that allow doctors to determine the reasons for infertility in most patients;
  • up to 80% of women can get pregnant after conservative therapy; 
  • the effectiveness of surgical treatment of infertility reaches 70%;
  • doctors use the latest assisted reproductive technologies, providing a pregnancy rate of up to 50% or more per embryo transfer (for women under the age of 38);
  • the use of special IVF protocols that help women get pregnant over the age of 40, even in the presence of somatic diseases and hormonal disorders;
  • the use of preimplantation screening, with which genetic and chromosomal abnormalities in the embryo may be detected even before its transfer to the uterus, allowing doctors to choose a genetically healthy embryo;
  • patients receive additional treatment to reduce the risk of a spontaneous abortion. 

You are welcome to visit the Booking Health website to choose a hospital. You can sort medical centers by the cost of treatment, rating, reviews, or nearest free appointment date. When you make your treatment appointment through Booking Health, prices will be lower than when you contact the hospital directly. The cost of treatment will be reduced due to the absence of taxes for foreign patients. The specialists at the Booking Health company will provide you with a full package of travel arrangement services.

 

Authors: 

The article was edited by medical experts, board-certified doctors Dr. Nadezhda Ivanisova and Dr. Vadim Zhiliuk. For the treatment of the conditions referred to in the article, you must consult a doctor; the information in the article is not intended for self-medication!

 

Sources:

Medical News Today

UpToDate

Healthline




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