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Treatment of Ovarian cancer

Due to the difficulties associated with the organization of treatment in Turkey, Switzerland, South Korea and India, we are not currently processing requests to these regions.

If you are interested in treatment in Germany, please leave a request and our specialists will contact you as soon as possible.

 

Cost for treatment

Ovarian Cancer Diagnostics
 from  733
Surgical treatment of ovarian cancer with laparoscopic salpingo-oophorectomy
 from  4163
Surgical treatment of ovarian cancer with extension to the pelvic organs and lymph nodes by hysterectomy, salpingo-oophorectomy and lymphadenectomy
 from  10295

University Hospital Tuebingen

9.2/10
location_onGermany, Tuebingen

Department of Adult and Pediatric Gynecology, Mammology, Obstetrics

According to the prestigious medical publication Focus, the University Hospital Tuebingen ranks among the top five German hospitals! The hospital was founded in 1805, therefore it is proud of its long history, unique experience, and outstanding achievements in the field of medical care, as well as research and teaching activitie
Ovarian Cancer Diagnostics
2931
Surgical treatment of ovarian cancer with laparoscopic salpingo-oophorectomy
12971
Surgical treatment of ovarian cancer with extension to the pelvic organs and lymph nodes by hysterectomy, salpingo-oophorectomy and lymphadenectomy
28450

Leverkusen Clinic

10/10
location_onGermany, Leverkusen

Department of Gynecology, Urogynecology, Mammology and Obstetrics

The Leverkusen Clinic is a progressive provider of high-quality diagnostic and therapeutic services in Germany. The medical facility is an Academic Hospital of the University of Cologne, and also maintains close cooperation with the Rhine Research Center. The medical facility houses 12 specialized departments, as well as numerou
Ovarian Cancer Diagnostics
2889
Surgical treatment of ovarian cancer with laparoscopic salpingo-oophorectomy
12469
Surgical treatment of ovarian cancer with extension to the pelvic organs and lymph nodes by hysterectomy, salpingo-oophorectomy and lymphadenectomy
26901

University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of Obstetrics, Adult and Pediatric Gynecology

The University Hospital Ulm started its activities 35 years ago and during this time it has become one of the most prestigious medical institutions in Europe. The hospital is famous for its numerous discoveries and the world-class achievements in medicine and pharmaceuticals. The medical facility has 29 specialized departments a
Ovarian Cancer Diagnostics
2931
Surgical treatment of ovarian cancer with laparoscopic salpingo-oophorectomy
13059
Surgical treatment of ovarian cancer with extension to the pelvic organs and lymph nodes by hysterectomy, salpingo-oophorectomy and lymphadenectomy
28525

University Hospital Rechts der Isar Munich

9.8/10
location_onGermany, Munich

Department of Gynecology, Mammology, Obstetrics and Perinatal Medicine

According to the prestigious FOCUS magazine, the University Hospital Rechts der Isar Munich ranks among the Germany's top medical institutions! Founded in 1834, the hospital combines long traditions and the very latest achievements of modern medicine. The medical facility includes 33 specialized departments, 20 interdiscipli
Ovarian Cancer Diagnostics
3034
Surgical treatment of ovarian cancer with laparoscopic salpingo-oophorectomy
13188
Surgical treatment of ovarian cancer with extension to the pelvic organs and lymph nodes by hysterectomy, salpingo-oophorectomy and lymphadenectomy
28381

University Hospital Carl Gustav Carus Dresden

9.1/10
location_onGermany, Dresden

Department of Adult and Pediatric Gynecology, Mammology and Obstetrics

According to the prestigious Focus magazine, the University Hospital Carl Gustav Carus Dresden is among the top three hospitals in Germany! The hospital is the embodiment of the standards of modern high-quality medicine. Since the hospital positions itself as a maximum care medical facility, it represents all medical fields. The
Ovarian Cancer Diagnostics
3515
Surgical treatment of ovarian cancer with laparoscopic salpingo-oophorectomy
15924
Surgical treatment of ovarian cancer with extension to the pelvic organs and lymph nodes by hysterectomy, salpingo-oophorectomy and lymphadenectomy
35419

University Hospital Frankfurt am Main

10/10
location_onGermany, Frankfurt am Main

Department of Adult and Pediatric Gynecology, Obstetrics and Mammology

According to the reputable Focus magazine, the University Hospital Frankfurt am Main ranks among the top German medical facilities! The hospital was founded in 1914 and today is a well-known German medical facility, which combines rich traditions and scientific innovations. A medical team of more than 6,500 employees cares about
Ovarian Cancer Diagnostics
2916
Surgical treatment of ovarian cancer with laparoscopic salpingo-oophorectomy
12188
Surgical treatment of ovarian cancer with extension to the pelvic organs and lymph nodes by hysterectomy, salpingo-oophorectomy and lymphadenectomy
26487

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Department of Adult and Pediatric Gynecology, Mammology

According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! The hospital is one of the largest and leading university medical complexes in Europe. The hospital in Germany provides modern diagnostics and treatment of patients, a
Ovarian Cancer Diagnostics
3915
Surgical treatment of ovarian cancer with laparoscopic salpingo-oophorectomy
18104
Surgical treatment of ovarian cancer with extension to the pelvic organs and lymph nodes by hysterectomy, salpingo-oophorectomy and lymphadenectomy
40442

University Hospital Heidelberg

9.8/10
location_onGermany, Heidelberg

Department of Obstetrics, Adult and Pediatric Gynecology

According to the Focus magazine, the University Hospital Heidelberg ranks among the top five hospitals in Germany! The hospital is one of the most advanced and reputable medical institutions not only in Germany, but throughout Europe. There are more than 43 specialized departments and 13 medical institutes, which cover all field
Ovarian Cancer Diagnostics
0
Surgical treatment of ovarian cancer with laparoscopic salpingo-oophorectomy
0
Surgical treatment of ovarian cancer with extension to the pelvic organs and lymph nodes by hysterectomy, salpingo-oophorectomy and lymphadenectomy
0

University Hospital of Ludwig Maximilian University of Munich

10/10
location_onGermany, Munich

Department of Obstetrics, Adult and Pediatric Gynecology

According to the Focus magazine, the University Hospital of Ludwig Maximilian University of Munich is regularly ranked among the best medical institutions in Germany! The hospital is the largest multidisciplinary medical facility, as well as a leading research and training center in Germany and Europe. The hospital is proud of i
Ovarian Cancer Diagnostics
3243
Surgical treatment of ovarian cancer with laparoscopic salpingo-oophorectomy
13595
Surgical treatment of ovarian cancer with extension to the pelvic organs and lymph nodes by hysterectomy, salpingo-oophorectomy and lymphadenectomy
30313

University Hospital Erlangen

9.1/10
location_onGermany, Erlangen

Department of Adult and Pediatric Gynecology, Mammology, Obstetrics

According to the Focus magazine, University Hospital Erlangen ranks among the best medical facilities in Germany! The hospital is one of the leading healthcare facilities in Bavaria and offers top-class medical care distinguished by the close intertwining of clinical activities with research and training of medical students. The
Ovarian Cancer Diagnostics
2997
Surgical treatment of ovarian cancer with laparoscopic salpingo-oophorectomy
13142
Surgical treatment of ovarian cancer with extension to the pelvic organs and lymph nodes by hysterectomy, salpingo-oophorectomy and lymphadenectomy
28553

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of Gynecology and Mammology

According to the prestigious Focus magazine, the University Hospital Halle (Saale) ranks among the top German medical facilities! The history of the hospital has more than 300 years, and during this time it managed to earn an excellent reputation not only in Germany, but throughout the world. The hospital positions itself as a s
Ovarian Cancer Diagnostics
2980
Surgical treatment of ovarian cancer with laparoscopic salpingo-oophorectomy
12148
Surgical treatment of ovarian cancer with extension to the pelvic organs and lymph nodes by hysterectomy, salpingo-oophorectomy and lymphadenectomy
26619

University Hospital Hamburg-Eppendorf

9.2/10
location_onGermany, Hamburg

Department of Gynecology and Mammology

According to the Focus magazine, the University Hospital Hamburg-Eppendorf ranks among the top ten hospitals in Germany! Since its foundation in 1889, the hospital has taken a leading position in the European medical arena and still occupies it until today. A highly competent medical team of more than 11,000 employees takes care
Ovarian Cancer Diagnostics
3480
Surgical treatment of ovarian cancer with laparoscopic salpingo-oophorectomy
15853
Surgical treatment of ovarian cancer with extension to the pelvic organs and lymph nodes by hysterectomy, salpingo-oophorectomy and lymphadenectomy
35294

University Hospital Würzburg

9.2/10
location_onGermany, Würzburg

Department of Adult and Pediatric Gynecology, Mammology and Obstetrics

According to the Focus magazine in 2019, the University Hospital Würzburg ranks among the top national German hospitals! The hospital is one of the oldest medical facilities in Germany. The centuries-old traditions of first-class treatment are combined with the very latest achievements of modern evidence-based medicine and
Ovarian Cancer Diagnostics
2960
Surgical treatment of ovarian cancer with laparoscopic salpingo-oophorectomy
12197
Surgical treatment of ovarian cancer with extension to the pelvic organs and lymph nodes by hysterectomy, salpingo-oophorectomy and lymphadenectomy
26481

University Hospital RWTH Aachen

8.9/10
location_onGermany, Aachen

Department of Gynecology, Mammology and Obstetrics

According to the prestigious Focus magazine, the University Hospital RWTH Aachen ranks among the top German hospitals! As a maximum care university medical facility, the hospital guarantees patients first-class medical services combined with a respectful and human attitude. The hospital integrates all the modern options for the
Ovarian Cancer Diagnostics
3152
Surgical treatment of ovarian cancer with laparoscopic salpingo-oophorectomy
13636
Surgical treatment of ovarian cancer with extension to the pelvic organs and lymph nodes by hysterectomy, salpingo-oophorectomy and lymphadenectomy
29876

University Hospital Duesseldorf

9.5/10
location_onGermany, Duesseldorf

Department of Adult and Pediatric Gynecology, Obstetrics and Mammology

According to the authoritative Focus magazine, the University Hospital Duesseldorf ranks among the top Germany hospitals! The hospital is an excellent example of a combination of high-quality health care, research and teaching activities. With more than 50,000 inpatients and about 300,000 outpatients every year, the hospital is
Ovarian Cancer Diagnostics
3222
Surgical treatment of ovarian cancer with laparoscopic salpingo-oophorectomy
13845
Surgical treatment of ovarian cancer with extension to the pelvic organs and lymph nodes by hysterectomy, salpingo-oophorectomy and lymphadenectomy
30125

University Hospital Muenster

9.8/10
location_onGermany, Muenster

Department of Adult and Pediatric Gynecology, Obstetrics

According to the Focus magazine, the University Hospital Muenster ranks among the top German hospitals! The hospital belongs to the most prestigious medical institutions in Germany. The hospital is distinguished by a high professionalism of its doctors, state-of-the-art technological equipment and the availability of the most ad
Ovarian Cancer Diagnostics
2834
Surgical treatment of ovarian cancer with laparoscopic salpingo-oophorectomy
12301
Surgical treatment of ovarian cancer with extension to the pelvic organs and lymph nodes by hysterectomy, salpingo-oophorectomy and lymphadenectomy
26575
| from Booking Health GmbH

Сontent

  1. Symptoms
  2. Diagnosis making
  3. Treatment options
  4. Surgery
  5. Chemotherapy
  6. Transarterial chemoembolization for ovarian cancer
  7. Why is HIPEC for ovarian cancer used?
  8. Clinical trials
  9. Ovarian cancer screening
  10. Why undergo treatment in hospitals abroad?
  11. The cost of treatment abroad
  12. Undergoing treatment abroad with Booking Health

 

Ovarian cancer occurs quite often in developed countries and includes a large and diverse group of ovarian malignant tumors. This disease is characterized by a complex diagnosis making and high mortality, since at the early stages it is asymptomatic. As a rule, it is detected at advanced stages, when patients have ascites and an increase in the abdomen in size, which most people pay attention to.

Ovarian cancer is diagnosed with transvaginal ultrasound scan, CT scan, and MRI.

Stage 4 ovarian cancer is cancer that spreads to lymph nodes and distant organs.

The most common methods of ovarian cancer treatment are surgery and chemotherapy, radiation therapy, hormone and targeted therapy.

Cost of treatment with laparoscopic surgery starts at €4,163. Price for surgery and HIPEC starts at €17,413. Cost of chemotherapy starts at €1,358.

Best hospitals in Europe are:

  • University Hospital Rechts der Isar Munich
  • University Hospital of Ludwig Maximilian University of Munich
  • Helios Hospital Berlin-Buch
  • University Hospital Frankfurt am Main
  • Clinic of Advanced Biological Medicine Frankfurt am Main

Symptoms

 

At the early stages, the symptoms of ovarian cancer are similar to those ones of benign tumors, i.e. they are virtually absent. Often, even large-size ovarian tumors do not bring any discomfort to the patient and do not cause menstrual irregularities.

Symptoms of ovarian cancer, such as bloating or discomfort in the lower abdomen, heaviness, difficulty urinating and defecating, constipation, pain, leg swelling, and thrombosis (caused by compression of the pelvic vein by the tumor), indicate a significant tumor size and a high probability of metastasizing. Due to the late treatment start, patients with ovarian cancer have a tumor that reached a significant size.

In addition to visiting the gynecologist regularly, indirect symptoms will also help to identify the development of ovarian cancer, affecting the hormonal background of the patient.

Considering the "secrecy" of ovarian cancer and the lack of regular preventive examinations, almost 80% of ovarian cancer cases are diagnosed at advanced stages.

Diagnosis making

 

It is important to understand that making the diagnosis and screening for the disease are not the same thing. Screening includes the assessment of potential indicators of the disease and is performed in healthy people in order to identify disease risks. Diagnostics establishes or excludes the presence of the disease and is carried out based on patient complaints or clinical manifestations (symptoms).

Tests and studies used for diagnostics in women with ovarian cancer include:

  • Gynecological examination
  • Transvaginal ultrasound scan
  • CT scan or MRI of the abdomen 
  • General urine analysis, complete blood count and biochemical blood test, blood test for tumor markers
  • Chest X-ray (allows assessing the spreading of the tumor process to the lungs)
  • In the case of a family history of ovarian cancer or breast cancer – genetic counseling and a genetic test to identify gene mutations
  • Taking a tissue sample for histological examination at the preoperative stage (diagnostic laparoscopy) or intraoperatively (at the time of tumor removal)

The prognosis depends on many factors, including the stage of the diagnosed tumor, the general health state of a patient with ovarian cancer, and response to therapeutic measures.

Treatment options

 

Currently, there are different treatment options for ovarian cancer.

Ovarian cancer treatment is most often conducted with the help of surgery. Chemotherapy for ovarian cancer treatment implies the use of its systemic type. The scheme of chemotherapy administration may vary, with the specific therapeutic regimen for every stage of the disease. Most often, chemotherapy is combined with targeted therapy. Targeted therapy implies using medications with the specific action on cancer cells in administration of which healthy cells remain intact.

Radiation therapy is rarely used for ovarian cancer treatment because there’s not enough evidence of the efficacy of its usage, although it can be used with palliative aims.

Surgery

 

Undoubtedly, the main method of treatment for patients with ovarian cancer at the early stages is the surgical one. The surgical intervention for the treatment for ovarian cancer should be the most complete. It includes removal of the uterus with fallopian tubes and ovaries on both sides in combination with resection of the greater omentum.

The operation can be performed both by means of laparotomy and from the laparoscopic approach if the spreading of the process and the small size of the tumor allow it.

If during diagnostic laparoscopy it is detected that a patient has a widespread tumor process, a biopsy of the tumor is performed. It is followed by the administration of preoperative polychemotherapy, taking into account the tumor histotype. Polychemotherapy aims to reduce the volume of tumor and achieve partial regression or shrinkage of the tumor. That will create conditions for the subsequent radical surgical treatment. In addition, laparoscopy can be used in the future as a "second-look" operation to monitor the state of clinical remission after the performed treatment.

Laparoscopy is much more sparing for the patient. Thus, the laparoscopic approach can be successfully used at all stages of examination and treatment of patients with ovarian cancer, both for diagnosis making and treatment.

Chemotherapy

 

All patients with ovarian cancer who have undergone surgery need additional chemotherapy. Chemotherapy is indicated in the following cases:

  • Before the surgical intervention, in order to improve its effectiveness and reduce the volume of surgery
  • In the case when it is impossible to remove the tumor, which significantly increases the survival rate
  • At the third or fourth stage of the disease, or after undergoing partial (palliative) surgery, in order to suppress the growth of the tumor
  • With radical removal, in order to reduce the risk of metastasizing and development of relapses

After surgical treatment of ovarian cancer has been performed, chemotherapy treatment should be started in almost all cases. Usually, it includes 3-4 courses, but it can be prolonged if necessary. Immediately after the operation, the woman must undergo the first course of treatment. The next ones are scheduled in 2 months and 6 months after the operation. If necessary, it is possible to undergo chemotherapy courses every six months.

Transarterial chemoembolization for ovarian cancer

 

Today, treatment for ovarian cancer is almost impossible without chemotherapy. But we all know that intravenous therapy not only destroys cancer cells but also negatively affects the entire body. Fortunately, medicine is constantly evolving, introducing additional high-tech methods of treating malignant pathologies.

One of them is transarterial chemoembolization for ovarian cancer.

This method allows for the precise delivery of the chemotherapy drug to the tumor through special "microspheres" that accumulate the chemotherapy drug in their structure.

Ovarian cancer is intensively supplied with arterial blood. Therefore, during transarterial chemoembolization for ovarian cancer, the drug is injected purposefully into the arterial vessel feeding the tumor. In transarterial chemoembolization for ovarian cancer, the blood flow is partially blocked with the help of these substances, creating a trap and stopping the supply of the tumor. During about 7-14 days, the chemotherapy drug is "washed off" into the tumor, providing a prolonged therapeutic effect of transarterial chemoembolization for ovarian cancer, due to which the malignant neoplasm shrinks.

Why is HIPEC for ovarian cancer used?

 

Many oncological pathologies that develop in the abdominal cavity or close to it affect the peritoneum (abdominal membrane). Cancer cells are often found there when tumors are originating in proximity. It relates to ovarian cancer as well, at its advanced stages.

In HIPEC for ovarian cancer (hyperthermic intraperitoneal chemotherapy):

  • Hyperthermia (heating of the chemotherapy drugs before entering the body) increases the killing impact of the selected chemotherapeutic substance on ovarian cancer cells
  • The heat itself has a powerful antitumor influence
  • Many tumor manifestations that the patient with ovarian cancer might have can be controlled

However, HIPEC for ovarian cancer isn’t indicated to patients with metastatic lesions beyond the abdominal region. HIPEC for ovarian cancer treatment isn’t used when there’s no possibility of all metastases destruction.

Clinical trials

 

Treatment of ovarian cancer becomes more successful every year thanks to elaboration of more effective and safer medicines in long-term and multicenter international clinical trials. A phase 1 of a clinical trial examines the safety and tolerability of an investigational drug in healthy volunteers. During the subsequent phases with the participation of patients, the effectiveness is determined, the safety and tolerability of the experimental therapy are clarified, including its comparison with the officially accepted standards for the treatment of the disease.

As a rule, the quality of international clinical trials is controlled by research sponsors, as well as by the international and domestic regulatory authorities.

International clinical trials are conducted in full compliance with current international rules and requirements of national legislation. To conduct clinical trials in hospitals, a consent of the ethical commissions at the medical institutions where the selected hospitals operate is required.

In order to participate in clinical trials, you need a doctor's opinion on this as well as your documented consent.

Ovarian cancer screening

 

Screening in medicine is a study (or several studies), with the help of which it is possible to identify a particular disease at an early stage when there are no symptoms yet. Screening is carried out with a certain regularity for people with medium risk or increased risk of developing a particular disease.

Ovarian cancer screening includes:

  • Transvaginal ultrasound of the ovaries (ovarian cancer is well visualized by the ultrasound waves)
  • A blood test for the tumor marker of ovarian cancer CA125 – a protein-antigen that is produced by cancer cells, therefore, its blood level increases in women with ovarian cancer

Why undergo treatment in hospitals abroad?

 

When the oncological diagnosis is detected, in four cases out of ten patients consider the option of undergoing treatment abroad. And this is reasonable, as the possibilities of European hospitals are ahead of the level of cancer centers outside the EU. In oncology hospitals in Europe, advanced methods and drugs are used for cancer treatment, surgery is at a high level, and the strict control of diagnostic and treatment protocols excludes the possibility of medical error.

Doctors in European hospitals do not perceive the diagnosis of cancer as a sentence, even when it comes to difficult cases, and the medical staff is friendly and positive.

Specialists of European hospitals are committed to teamwork. The employees are well trained and they constantly improve their knowledge and skills. Hospitals pay attention to continuous professional development, which allows specialists to achieve great results when prescribing anticancer care.

In addition, foreign hospitals have quality management systems implemented and certified. Medical technology is only modern and safe, and this is obvious.

Hospitalization of a new patient can be as quick as possible in order to avoid deteriorating health while waiting for treatment. Patients with severe health conditions are first offered help in foreign hospitals.

To receive a consultation about the best hospital for treatment of your diagnosis, leave a request on the Booking Health website.

The cost of treatment abroad

 

When choosing a country, it is necessary to take into account the ratio of the quality of treatment and its cost. The cost of treatment consists of hospital services (consultation of a doctor, diagnosis making, treatment, rehabilitation, and hospitalization).

To make it easier to navigate, we collected information about the cost of treatment in different countries.

The cost of treatment with chemotherapy in Germany starts at 4,301 EUR. The minimal price for treatment in Turkey is 2,477 EUR. The minimal price for treatment in India is 4,844 EUR.

The cost of treatment with CRS and HIPEC in Germany starts at 38,009 EUR. The minimal price for treatment in Turkey is 29,257 EUR. The minimal price for treatment in Israel is 64,454 EUR.

The cost of treatment with laparoscopic salpingo-oophorectomy in Germany starts at 10,744 EUR. The minimal price for treatment in Turkey is 6,971 EUR. The minimal price for treatment in India is 15,562 EUR.

Contact Booking Health to specify prices for undergoing treatment abroad for your diagnosis.

Undergoing treatment abroad with Booking Health

 

There are many peculiarities of organizing the treatment abroad. There are options out there that will save your time and money. One of them is using the services of the medical tourism agency.

Booking Health is the company with years of experience in medical tourism. Booking Health will help prepare medical documents, issue a medical visa even during the lockdown, organize the flight, accommodation, and transfer for you, and provide you with support throughout the whole duration of treatment abroad.

Booking Health will be happy to assist you in the organization of treatment abroad and provide you with hospital options that suit you in terms of financial and other matters.

Leave a request on the Booking Health website, and a medical advisor will contact you shortly.

Authors: Dr. Nadezhda IvanisovaDr. Farrukh Ahmed




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