University Hospital Cologne
Department of Oncology, Hematology, Clinical Infectology, Clinical Immunology, Hemostaseology, Internal Intensive Care (26185)
Specialized in: oncology, hematology, clinical infectology, clinical immunology, hemostaseology, internal intensive care
About the department
The Department of Oncology, Hematology, Clinical Infectology, Clinical Immunology, Hemostaseology, General Intensive Care at the University Hospital Cologne offers the full range of diagnostics and treatment in these medical fields. All areas of clinical practice are represented by a specially trained highly competent team of doctors who use their experience and skills to ensure the most favorable treatment outcome. The department is headed by Prof. Dr. med. Michael Hallek.
The department focuses on the treatment of malignant blood diseases, lymphatic diseases, infections, including HIV infection, immunodeficiencies, bleeding disorders, etc. Also, the department’s doctors have excellent qualifications in the field of blood stem cell transplantation.
One of the department’s priorities is the treatment of blood malignancies and solid tumors. Any oncopathology requires an integrated and interdisciplinary approach. Consequently, the department works in close cooperation with the Comprehensive Cancer Center Cologne, which brings together the best experts from Germany. In addition to the classical spectrum of therapy, for example, chemotherapy, radiation therapy, antibody therapy, etc. patients are also offered innovative treatment options. One of these advanced techniques is CAR T-cell therapy. The essence of this new therapeutic approach is that the body’s own protective cells (T cells) are genetically modified to recognize and destroy cancer cells. The first stage of the treatment procedure is the collection of the patient's T-cells (leukapheresis). Then the selected cells are processed in the laboratory (selection, transduction and expansion). The final stage is the infusion of genetically modified CAR T-cells into the patient’s bloodstream. CAR T-cells recognize CD19-positive cells in the body, after which they activate, multiply and attack CD19-positive cancer cells. CAR T-cell therapy is an innovative cellular immunotherapy, which is currently available only in the advanced medical centers in developed countries.
The service range of the department includes:
- Diagnostics and treatment of malignancies of the gastrointestinal tract (esophagus, stomach, intestines)
- Diagnostics and treatment of lung cancer
- Diagnostics and treatment of sarcomas
- Diagnostics and treatment of acute leukemias (AML, ALL) and myelodysplastic syndromes
- Diagnostics and treatment of chronic lymphocytic leukemia
- Diagnostics and treatment of Hodgkin's lymphoma
- Diagnostics and treatment of multiple myeloma
- Diagnostics and treatment of non-Hodgkin lymphoma
- Blood stem cell transplantation
- Clinical infectology
- Diagnostics and treatment of all infections (special focus on the treatment of patients with HIV infection, tuberculosis)
- Clinical immunology
- Rheumatoid arthritis
- Psoriatic arthritis
- Ankylosing spondylitis
- Systemic lupus erythematosus
- Systemic scleroderma
- Sjogren's syndrome
- Diagnostics and treatment of all bleeding disorders, including hemophilia A and B, von Willebrand syndrome, thrombophilia, hemorrhagic diathesis, etc.
- General intensive care
- Classic intensive care
- Intensive care for severe forms of pneumonia, sepsis and septic multiple organ failure, especially in immunocompromised patients
- Extracorporeal membrane oxygenation
- Other medical services
- 1978 - 1985 Study of Medicine at the Universities of Regensburg, Munich and Paris.
Academic and Professional Background
- Since 2007, Director of the Comprehensive Cancer Center Cologne-Bonn based at the Universities of Cologne and Bonn.
- Since 2003 Head of the Department of Oncology, Hematology, Clinical Infectology, Clinical Immunology, Hemostaseology, General Intensive Care at the University Hospital Cologne.
- 1999 - 2003 C3 Professorship for Internal Medicine, Ludwig Maximilian University of Munich.
- 1998 - 2005 Leader, Clinical Research Group GSF, Helmholtz Institute, Munich.
- 1995 - 2003 Senior Physician at the University Hospital of Ludwig Maximilian University of Munich.
- 1994 - 2005 Leader of the Working Group on Gene Therapy, Gene Center, Ludwig Maximilian University of Munich.
- 1992 - 1995 Assistant Physician, University Hospital Innenstadt.
- 1990 - 1992 Fellow, Dana Farber Cancer Institute, Harvard Medical School, Boston, USA.
- 1985 - 2003 Various internships abroad; training in Pharmacology, Internal Medicine, Hematology and Oncology at the University Hospital Rechts der Isar Munich and the University Hospital of Ludwig Maximilian University of Munich.
Positions in Scientific Societies and Committees (selected)
- Since 2018 Chairman of the Scientific Committee of the European School of Hematology, Paris, France.
- Since 2016 Chairman and since 2018 Managing Chairman of the German Society for Hematology and Medical Oncology (DGHO).
- Since 2014 Member of the Scientific Advisory Board of the German Medical Association.
- 2014 - 2017 Member of the Scientific Committee of the American Society of Hematology (ASH).
- 2014 - 2015 Chairman of the Board of the German Society of Internal Medicine (DGIM).
- 2014 President of the German Cancer Congress 2014.
- 2013 - 2016 Member of the Senate Commission on the Main Issues of Clinical Trials of the German Research Foundation (DFG).
- Since 2011 Editor of Oncology Research and Treatment.
- Since 2000 Member of the International Working Group for the Study of Chronic Lymphocytic Leukemia.
- 1996 Founder and Leader of the German Research Group on Chronic Lymphocytic Leukemia.
Awards and Honorary Memberships (selected)
- 2018 Johann Georg Zimmermann Medal.
- 2017 Arthur Burkhardt Prize.
- 2017 Award for Achievements in Cancer Research (Deutscher Krebspreis).
- 2016 Walter Siegenthaler Gold Medal.
- 2013 Binet Rai Medal.
- 2012 Paul Martini Award.
- Since 2011 Member of the National Academy of Sciences Leopoldina.
- Since 2008 Many awards from the Comprehensive Cancer Center Cologne-Bonn.
- 1999 Artur Pappenheim Prize of the German Society for Hematology and Oncology.
Department of Oncology, Hematology, Clinical Infectology, Clinical Immunology, Hemostaseology, Internal Intensive Care.
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